Horrigan, US
David John Horrigan, Encinitas, CA US
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20080228041 | Method and System for Remote Diagnosis and Supervision of Complex Procedures - A network enabled method and system for better utilizing expert or licensed individuals to address or treat a greater quantity of situations at a lower cost and at greater convenience allowing numerous companies to have access to such expert or liscensed resources. This business model involves a trained assistant gathering appropriate data and transmitting it to a central or remote location where the specialist can review it and transmit a diagnosis or directions to the assistant to execute. The expert then collects the fees for the procedure and distributes proceeds to the assistant, assistants company or coordinating third party. | 09-18-2008 |
20080287912 | Method, Device And Formulation For The Treatment Of Nail Disorders - An improved method, device and formulation for the treatment of nail disorders characterized by de-lamination, thickening or crumbling of the nails. The invention consists of a tubular proboscis ( | 11-20-2008 |
20100057022 | Method and Device for the Cleaning and Medical Treatment of Extremities - The use of elastomeric gloves, slippers, finger and toe covers for the cleaning, debriding and application of medicines by utilizing the repeated self-contained flushing and pumping caused by normal appendage motion and elastomeric distortion and equalization either alone or in tandem with the auxiliary agitation from an external ultrasonic source if necessary. | 03-04-2010 |
Holly Horrigan, Needham, MA US
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20100174663 | REIT-Based Pure Property Return Indexes - The present disclosure is directed to generating REIT-based pure property return indexes. First, REIT return data is compiled from each REIT of a plurality of REITs at a predetermined frequency. Then, the generated REIT return data is de-levered and processed according to exposures to each of a plurality of target characteristics to obtain coefficients reflecting each REIT's weight in an index. Finally, an index is generated according to the REITs, the obtained coefficients, and the weights. | 07-08-2010 |
20110320327 | Backward/Forward Trading Contracts Based on REIT-Based Pure Property Return Indexes - The present disclosure is directed to a method of approximating prices in a private property market. First, REIT return data is compiled from each REIT of a plurality of REITs at a predetermined frequency. Then, the REIT return data is processed according to exposures to each of a plurality of target characteristics to obtain coefficients reflecting each REIT's weight in an index. Then, an index is generated according to the REITs, the obtained coefficients, and the weights. Finally, a second index is derived from the generated index that approximates prices in the private property market. | 12-29-2011 |
John B. Horrigan, Beverly, MA US
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20080242964 | MEDICAL LEAD DELIVERY DEVICE - The medical lead delivery device combines features of a guidewire and a stylet in order to more easily and quickly deliver a lead to or through the coronary vein of a patient's heart. The medical lead delivery device includes an elongated body, a controller, a first and second spring, and a sleeve. The elongated body includes a proximal end and a distal end. The controller is disposed at the proximal end and provides enhanced control of the distal tip of the elongated body. | 10-02-2008 |
20120323254 | MEDICAL ASSEMBLIES AND METHODS FOR IMPLEMENTATION OF MULTIPLE MEDICAL LEADS THROUGH A SINGLE ENTRY - Assemblies and methods provide for implantation of multiple medical leads to a defined space within the body, such as the epidural space, through a single entry. A catheter having multiple lumens or alternatively a single oblong lumen may be used. A distal end of the catheter enters the defined space through the single entry such that the distal ends of the multiple lumens or the oblong lumen are present in the defined space. Medical leads are introduced through the multiple lumens or the oblong lumen into the defined space. In some cases, the distal end of the catheter may be deflectable to direct the medical leads within the defined space. In other cases, sheaths may be present within each lumen of the catheter where the sheaths may be extended into the defined space and deflect to direct the medical leads that are being passed through a lumen of the sheaths. | 12-20-2012 |
Stephen Horrigan, Gaithersburg, MD US
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20130123281 | Compositions and Methods for Inhibition of TBL-1 Binding to Disease-Associated Molecules - Compositions and methods which modulate diseases and disorders related to transducin β-like protein 1 (TBL1) activity, including but not limited to cancer, inflammation, and bone related diseases. | 05-16-2013 |
20130143920 | Methods for treatment of diseases and disorders related to transducin beta-like protein 1 (TBL1) activity, including myeloproliferative neoplasia and chronic myeloid leukemia. - Methods for treatment of diseases and disorders related to transducin β-like protein 1 (TBL1) activity, including myeloproliferative neoplasia, chronic myeloid leukemia, and acute myeloid leukemia. | 06-06-2013 |
Stephen K. Horrigan, Poolesvile, MD US
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20100093611 | COMPOUNDS AND METHODS FOR TREATING OR PREVENTING AUTOIMMUNE DISEASES - Methods of treating, ameliorating, preventing, or reducing the risk of developing an auto-immune disease and/or an inflammatory condition, such as systemic lupus erythematosus, in a patient, such as a human being, using a therapeutically effective amount of an agent(s) that inhibits the activity of one or more of histone deacetylase (HDAC), I | 04-15-2010 |
Stephen K. Horrigan, Poolesville, MD US
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20080305493 | Determining Cancer-Linked Genes and Therapeutic Targets Using Molecular Cytogenetic Methods - Methods for identifying antineoplastic agents by using their ability to modify expression of specific genes or the biological activity of polypeptides encoded by such genes, wherein said genes are located in specific chromosomal regions, called amplicons, or regions of interest, and the presence of such amplified regions within a cancerous cell, are disclosed. Also described are methods for diagnosing cancerous, or potentially cancerous, conditions using these methods. Also encompassed are methods involving determining the modulated expression of the genes in these regions of interest (ROIs), or amplicons, as pharmacodynamic/pharmacogenetic/surrogate markers and/or for patient profiling prior to accrual for clinical trials/treatments based on the identification of these genes as validated gene/drug targets in various cancer tissue types. | 12-11-2008 |
20090192046 | Chemo-selective identification of therapeutics - Disclosed is the use of a therapeutic filter for simultaneous screening against multiple targets coupled with subsequent in silico drug discovery utilizing biologically active compounds for the identification and selection of gene sets having characteristic expression profiles for formation of an active compound database with subsequent identification of therapeutically effective agents by scanning and matching in said active compound database. | 07-30-2009 |