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Honghua
Honghua Li, Monmouth Junction, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20100297622 | Method for high-throughput gene expression profile analysis - The present invention embraces a method for high-throughput gene profiling with high specificity and sensitivity. With this system, >1000 mRNA species can be co-amplified using gene-specific primers from a single cell. The primers are designed to amplify sequences of desirable length, which are in different exons. The exons can be either adjacent and separated by a large intron or include more than two exons. The amplified sequences are then analyzed by microarray with probes hybridizing to neighboring exons. | 11-25-2010 |
Honghua Yang, Cherry Hill, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20100291580 | BIOMARKERS FOR TRICHOGENICITY - Biomarkers for identifying trichogenic cells have been identified. The biomarkers include microRNA as wells as mRNA and proteins. Certain biomarkers are upregulated in trichogenic cells compared to non-trichogenic cells; whereas, other biomarkers are down-regulated in trichogenic cells compared to non-trichogenic cells. The cells can be dermal cells, epidermal cells, or a combination thereof. Preferably the cells are mammalian, more preferably the cells are human. One embodiment provides a method for selecting trichogenic cells by assaying the cells for expression of one or more biomarkers for trichogenicity, and selecting the cells having increased expression of the one or more biomarkers relative to a control, wherein increased expression of the a biomarker in the cells is indicative of trichogenicity. Preferably, the one or more biomarkers are selected from the group consisting of hsa-miR-200c, hsa-miR-205, hsa-miR-200a*, hsa-miR-200a, hsa-miR-141, hsa-miR-182, DEPDC1, hFLEG1, ESM1, TOME-1, THBD and combinations thereof. | 11-18-2010 |
Honghua Zhou, Jiangxi CN
| Patent application number | Description | Published |
|---|---|---|
| 20100054575 | Analysis method for 5-differential complete blood cell based on visual image - An analysis method for five-differential complete blood cell based on visual image is provided. The analysis method for five-differential complete blood cell is carried out in two channels. The method includes: counting blood cells by typical cytometry to obtain the amount of blood cells; identifying and counting the blood cells by image recognition to obtain the percent of each kind of blood cells; then calculating the results from the two channels to obtain the number of each kind of blood cells. | 03-04-2010 |