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Holterman

Chet Holterman, Embrun CA

Patent application numberDescriptionPublished
20090074730NOVEL STEM CELLS, NUCLEOTIDE SEQUENCES AND PROTEINS THEREFROM - The present invention provides novel stem cells, nucleotide sequences and proteins therefrom. More specifically, the present invention provides Pax7+/Myf5− stem cells and methods for identifying and isolating them. Also provided is a MEGF10 nucleotide sequence and protein.03-19-2009

Jan Holterman, Delden NL

Patent application numberDescriptionPublished
20110247389Device for Clamping a Tool - Disclosed is a clamping device for clamping a tool, which includes a part receiving the tool, an actuated member and an engaging member to be brought into contact with the tool. The clamping device is further provided with a transmission placed between the actuated member and the engaging member. The actuated member can be pneumatically or electrically driven, and includes for instance a pneumatic jack, an electric motor or a piezoelectric element or an electromagnet. The actuated member can also be hydraulically driven. The transmission can include a wedge-shaped member or a lever. The clamping device can be self-braking.10-13-2011

Lennart Holterman, Zoetemeer NL

Patent application numberDescriptionPublished
20110311580Settings for recombinant adenoviral-based vaccines - Described are new uses of recombinant adenoviral vectors in vaccination regimens, such as prime/boost set-ups and subsequent vaccinations and applications for gene therapy. Moreover, also described are new assays to determine the best regimen for applying the most suitable recombinant viral vector in a vaccination or gene therapy setting.12-22-2011

Lennart Holterman, Zoetermeer NL

Patent application numberDescriptionPublished
20080220014Recombinant viral-based malaria vaccines - The present invention relates to novel vaccines against malaria infections, based on recombinant viral vectors, such as alpha viruses, adenoviruses or vaccinia viruses. The recombinant viral-based vaccines can be used to immunize against different 09-11-2008
20100015176Settings for recombinant adenoviral-based vaccines - The present invention provides new uses of recombinant adenoviral vectors in vaccination regimens, such as prime/boost set-ups and subsequent vaccinations and applications for gene therapy. Moreover, the invention provides new assays to determine the best regimen for applying the most suitable recombinant viral vector in a vaccination or gene therapy setting.01-21-2010
20100172928Recombinant viral-based malaria vaccines - The present invention relates to novel vaccines against malaria infections, based on recombinant viral vectors, such as alpha viruses, adenoviruses or vaccinia viruses. The recombinant viral-based vaccines can be used to immunize against different 07-08-2010
20110150930Recombinant viral-based malaria vaccines - Described are vaccines against malarial infections, which are based on recombinant viral vectors, such as alpha viruses, adenoviruses, or vaccinia viruses. The recombinant viral-based vaccines can be used to immunize against different 06-23-2011

Patent applications by Lennart Holterman, Zoetermeer NL

Mark Holterman, Chicago, IL US

Patent application numberDescriptionPublished
20110002956MUTANT HUMAN CD80 AND COMPOSITIONS FOR AND METHODS OF MAKING AND USING THE SAME - Improved vaccines and methods of using the same are disclosed Immunosuppressive compositions for treating individuals who have autoimmune diseases or transplants and methods of using the same are disclosed.01-06-2011

Mark J. Holterman, River Forest, IL US

Patent application numberDescriptionPublished
20090232854USES OF BISPECIFIC ANTIBODY COATED DENDRITIC CELLS PULSED WITH ANTIGENS AND GM-CSF IN IMMUNE REGULATION - GM-CSF administered before immunization exerted a sustained suppressive effect against the induction of myasthenia gravis (MG). This suppression was associated with lowered serum autoantibody levels, reduced T cell proliferative responses to AChR, and an expansion in the population of FoxP3+ regulatory T cells. Manipulating DCs to expand regulatory T cells is useful for the control of autoimmune diseases such as myasthenia gravis MG.09-17-2009

Martijn Hermanus Maria Holterman, Wageningen NL

Patent application numberDescriptionPublished
20100062439Method for Detecting Cyst Nematodes - The present invention relates to a method for determining the presence of a cyst nematode in a sample comprising the steps of : providing a pair of bidirectional oligonucleotide primers or an oligonucleotide probe that hybridizes specifically, under stringent hybridization conditions, to a nucleic acid sequence encoding the SSU rRNA or LSU rRNA, or the complement or transcript thereof, of a sub genus-cluster of nematodes, said subgenus-cluster comprising cyst nematodes belonging to at least one species of nematode, and wherein said primers or probe do not hybridize to a nucleic acid sequence encoding the LSU rRNA, or the complement or transcript thereof, of cyst nematodes not part of said subgenus-cluster of cyst nematodes; providing a sample in which the presence of the cyst nematode is to be detected, and performing a nucleic acid detection assay on said sample using said pair of bidirectional oligonucleotide primers or said oligonucleotide probe.03-11-2010
20100081133Methods of Detecting Root Knot Nematodes - The present invention relates to a method of testing a sample for the presence of a 04-01-2010

Steven W. Holterman, Franklin, WI US

Patent application numberDescriptionPublished
20110198553Wedge Post Base System - A wedge post-base system for adjusting the orientation of an attached post relative to a mounting surface is disclosed. The base utilizes a two-piece structure, each piece having an angled mating surface relative to an opposing surface which allows a central axis of a post mounting collar to be altered, and thus the angle of the post itself. The resulting angle addresses the issue of mounting posts on a sloped plane. A fencing system having hinged railings and balusters as well as a railing system having a hinged upper rail are also disclosed.08-18-2011