Inventors list

Assignees list

Classification tree browser

Top 100 Inventors

Top 100 Assignees


Holmquist, US

Arnold L. Holmquist, San Diego, CA US

Patent application numberDescriptionPublished
20100041971IMPLANTABLE ANALYTE SENSOR - An implantable analyte sensor including a sensing region for measuring the analyte and a non-sensing region for immobilizing the sensor body in the host. The sensor is implanted in a precisely dimensioned pocket to stabilize the analyte sensor in vivo and enable measurement of the concentration of the analyte in the host before and after formation of a foreign body capsule around the sensor. The sensor further provides a transmitter for RF transmission through the sensor body, electronic circuitry, and a power source optimized for long-term use in the miniaturized sensor body.02-18-2010

Barton Holmquist, Eagle, NE US

Patent application numberDescriptionPublished
20090215987PEPTIDE AMIDATION PROCESS - The invention provides a process for amidating a desired peptide comprising cleaving a substrate polypeptide at a X08-27-2009

Patent applications by Barton Holmquist, Eagle, NE US

Brett Holmquist, West Hills, CA US

Patent application numberDescriptionPublished
20110226945METHODS FOR DETECTING DIHYDROXYVITAMIN D METABOLITES BY MASS SPECTROMETRY - Provided are methods of detecting the presence or amount of a dihydroxyvitamin D metabolite in a sample using mass spectrometry. The methods generally comprise ionizing a dihydroxyvitamin D metabolite in a sample and detecting the amount of the ion to determine the presence or amount of the vitamin D metabolite in the sample. In certain preferred embodiments the methods include immunopurifying the dihydroxyvitamin D metabolites prior to mass spectrometry. Also provided are methods to detect the presence or amount of two or more dihydroxyvitamin D metabolites in a single assay.09-22-2011

Brett Holmquist, Mission Viejo, CA US

Patent application numberDescriptionPublished
20090137056METHODS FOR DETECTING DIHYDROXYVITAMIN D METABOLITES BY MASS SPECTROMETRY - Provided are methods of detecting the presence or amount of a dihydroxyvitamin in D metabolite in a sample using mass spectrometry. The methods generally comprise ionizing a dihydroxyvitamin D metabolite in a sample and detecting the amount of the ion to determine the presence or amount of the vitamin D metabolite in the sample. In certain preferred embodiments the methods include immunopurifying the dihydroxyvitamin D metabolites prior to mass spectrometry. Also provided are methods to detect the presence or amount of two or more dihydroxyvitamin D metabolites in a single assay.05-28-2009
20110133068VITAMIN D METABOLITE DETERMINATION UTILIZING MASS SPECTROMETRY FOLLOWING DERIVATIZATION - The invention relates to the detection of vitamin D metabolites. In a particular aspect, the invention relates to methods for detecting derivatized vitamin D metabolites by mass spectrometry.06-09-2011
20110133069METHODS FOR DETECTING DIHYDROXYVITAMIN D METABOLITES BY MASS SPECTROMETRY - Provided are methods of detecting the presence or amount of a dihydroxyvitamin D metabolite in a sample using mass spectrometry. The methods generally comprise ionizing a dihydrorxyvitamin D metabolite in a sample and detecting the amount of the ion to determine the presence or amount of the vitamin D metabolite in the sample. In certain preferred embodiments the methods include immunopurifying the dihydroxyvitamin D metabolites prior to mass spectrometry. Also provided are methods to detect the presence or amount of two or more dihydroxyvitamin D metabolites in a single assay.06-09-2011
20110220785METHODS FOR DETECTING VITAMIN D METABOLITES BY MASS SPECTROMETRY - Provided are methods of detecting the presence or amount of a vitamin D metabolite in a sample using mass spectrometry. The methods generally comprise ionizing a vitamin D metabolite in a sample and detecting the amount of the ion to determine the presence or amount of the vitamin D metabolite in the sample. Also provided are methods to detect the presence or amount of two or more vitamin D metabolites in a single assay.09-15-2011
20110226944VITAMIN D METABOLITE DETERMINATION UTILIZING MASS SPECTROMETRY FOLLOWING DERIVATIZATION - The invention relates to the detection of vitamin D metabolites. In a particular aspect, the invention relates to methods for detecting derivatized vitamin D metabolites by mass spectrometry.09-22-2011

Patent applications by Brett Holmquist, Mission Viejo, CA US

Christopher Holmquist, Wilmington, DE US

Patent application numberDescriptionPublished
20110136804Nicotinic Acetylcholine Receptor Ligands 101 - Nicotinic acetylcholine receptor ligands of Formula I06-09-2011

Christopher R. Holmquist, Wilmington, DE US

Patent application numberDescriptionPublished
20090012127Thiophene-2-Carboxamide Derivatives as Alpha 7 Nicotinic Receptor Modulators - Compounds of Formula (I) wherein E, A and R1 are as described in the specification, pharmaceutically-acceptable salts, methods of making, pharmaceutical compositions containing and methods for using the same.01-08-2009

Eric B. Holmquist, South Windsor, CT US

Patent application numberDescriptionPublished
20090090182MEASURING ROTOR IMBALANCE VIA BLADE CLEARANCE SENSORS - A system and method can be utilized to determine an out of balance condition of a rotor having a plurality of blades. The system monitors a clearance between the blades and an associated housing. By looking at a center of that clearance information, a determination can be made of the magnitude of imbalance of the rotor.04-09-2009
20100288045MEASURING ROTOR IMBALANCE VIA BLADE CLEARANCE SENSORS - A system and method can be utilized to determine an out of balance condition of a rotor having a plurality of blades. The system monitors a clearance between the blades and an associated housing. By looking at a center of that clearance information, a determination can be made of the magnitude of imbalance of the rotor.11-18-2010

Patent applications by Eric B. Holmquist, South Windsor, CT US

Kurt Holmquist, Lutz, FL US

Patent application numberDescriptionPublished
20090012455DIALYSIS SYSTEM HAVING SUPPLY CONTAINER AUTOCONNECTION - A dialysis system includes a dialysis instrument including at least one pump actuator; a disposable cassette operable with the at least one pump actuator, a plurality of supply lines connected to the disposable cassette, each supply line including a supply line connector and a supply line tip protector; a plurality of dialysis fluid containers, the dialysis fluid containers each including a solution line having a solution line connector and a solution line tip protector; and an auto-connection mechanism including a solution line connector holder, a supply line connector holder, one of the holders fixed, the other of the holders moveable, and a moveable tip protector remover.01-08-2009
20100053330SECURITY SYSTEM USING LADAR-BASED SENSORS - A security sensor system comprises one or more laser detection and ranging (LADAR) sensors configured for accumulation of three-dimensional image data. In one embodiment, the one or more LADAR sensors each comprise a LADAR device, such as a MEMS device, configured to transmit a plurality of laser pulses, and a microprocessor operatively coupled to the LADAR device. One or more data storage devices is operatively coupled to the microprocessor and configured to store the three-dimensional image data, as well as predetermined protected area boundary and fixed object definitions. A GPS receiver can be operatively coupled to the microprocessor and a GPS antenna. The microprocessor is configured to perform a LADAR image analysis that compares the three-dimensional image data with the protected area boundary and fixed object definitions to identify one or more potential intruders.03-04-2010
20100134285METHOD OF SENSOR DATA FUSION FOR PHYSICAL SECURITY SYSTEMS - A method of sensor data fusion in a physical security system of a monitored area is provided. The method comprises receiving data inputs from one or more sensors in the physical security system, with the monitored area being overlaid with a grid defining a plurality of locations. The method further comprise selecting one or more potential paths of one or more potential intruders through the monitored area using an iterative process, which takes into consideration a sequence of sensor inputs and assumed limitations on the mobility of the one or more potential intruders. A confidence metric is then produced for each selected potential path.06-03-2010
20100229366DIALYSIS METHOD HAVING SUPPLY CONTAINER AUTOCONNECTION - A method for connecting a plurality of solution line connectors to a plurality of supply line connectors of a dialysis system includes: translating a tip protector remover in a first direction towards the plurality of supply line connectors to remove a plurality of solution line tip protectors from the plurality of solution line connectors; locking the tip protector remover to each of a plurality of supply line tip protectors connected to the plurality of supply line connectors; translating the tip protector remover in a second direction towards the plurality of solution line connectors to remove the plurality of supply line tip protectors from the supply line connectors; translating the tip protector remover in a third direction different from the first and second directions; translating one of the plurality of solution line connectors and the plurality of supply line connectors the other of the solution line connectors and the supply line connectors to connect each of the solution line connectors to one of the supply line connectors.09-16-2010
20110021231SYSTEM AND METHOD OF AUTOMATICALLY MAINTAINING A LINE-OF-SIGHT COMMUNICATION CHANNEL - One exemplary embodiment is directed to a method of automatically maintaining a line-of-sight communication channel. The method comprises determining information about each communication resource that is accessible in a region through which a mobile system is moving. The method further comprises determining information about the mobile system. The method further comprises performing a line-of-sight (LOS) analysis for each of the communication resources based at least in part on a respective location and a respective elevation for the respective communication resource and the current location of the mobile system and a current elevation for the mobile system. The method further comprises determining if a new communication link should be established with at least one of the communication resources based at least on the LOS analyses that were performed and establishing the new communication link if it is determined that the new communication link should be established.01-27-2011

Patent applications by Kurt Holmquist, Lutz, FL US

Tabitha L. Holmquist, Seattle, WA US

Patent application numberDescriptionPublished
20080300035Clear Path Electronic Game - A clear path electronic game is described in which one or more vessels are placed adjacent a mines of various sizes on rows of a grid. The game player then activates one mine at a maximum size to shoot a projectile at another mine. The mine shooting the projectile is removed. When the projectile hits the mine, the mine either grows or is removed from the grid. In response to the mine on the row adjacent one of the vessels being removed, the vessel is moved in its row across the former location of the removed mine. The vessel continues to move in the row off of the grid unless there is another mine in the row. Points are awarded for removing vessels and mines. Play ends when all maximum size mines are removed and when there are not vessels of the first type that has been removed from the grid.12-04-2008