Hollfelder
Florian Hollfelder, Cambridge GB
Patent application number | Description | Published |
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20100210479 | METHOD OF SYNTHESIS AND TESTING OF COMINATORIAL LIBRARIES USING MICROCAPSULES - Methods for use in the synthesis and identification of molecules which bind to a target component of a biological system or modulate the activity of a target are described. | 08-19-2010 |
20120010098 | SELECTION BY COMPARTMENTALISED SCREENING - The invention describes a method for the identification of compounds which bind to a target component of a biochemical system or modulate the activity of the target, by compartmentalizing the compounds into microcapsules together with the target, such that only a subset of the repertoire is represented in multiple copies in any one microcapsules; and identifying the compound which binds to or modulates the activity of the target. The invention enables the screening of large repertoires of molecules which can serve as leads for drug development. | 01-12-2012 |
20120010107 | SELECTION BY COMPARTMENTALISED SCREENING - The invention describes a method for the identification of compounds which bind to a target component of a biochemical system or modulate the activity of the target, by compartmentalizing the compounds into microcapsules together with the target, such that only a subset of the repertoire is represented in multiple copies in any one microcapsules; and identifying the compound which binds to or modulates the activity of the target. The invention enables the screening of large repertoires of molecules which can serve as leads for drug development. | 01-12-2012 |
Hans-Peter Hollfelder, Furth DE
Patent application number | Description | Published |
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20120070241 | TOOL HAVING DETACHABLY CLAMPED CUTTING BODY - The invention relates to a tool, in particular a revolving tool for machining, in particular metal cutting, workpieces, comprising a carrier body, a cutting body arranged detachably on the carrier body, and a clamping bracket for the positionally accurate fixation of the cutting body relative to the carrier body, wherein the cutting body is pressed against a supporting surface on the carrier body in a planar manner. According to the invention, the clamping bracket is integral with the carrier body and connected to the carrier body by way of a material joint. Furthermore, the cutting body is supported in the direction of the material joint on a face supporting surface of the clamping bracket, wherein the supporting surface is arranged on the carrier body at an acute angle (α) with respect to the face supporting surface of the clamping bracket and oriented in the direction of the material joint. | 03-22-2012 |
Nadine Hollfelder, Stuttgart DE
Patent application number | Description | Published |
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20130344577 | LIQUID CRYSTAL BASED SENSOR DEVICES FOR DETECTING TOXINS, BACTERIA AND THEIR ACTIVITIES - A liquid crystal based sensor device for detecting analytes. A method of manufacturing liquid crystal based sensor devices for detecting analytes. A method for at least one of (i) detecting analytes with a liquid crystal based sensor device; (ii) detecting the activity of analytes; and (iii) detecting screening compounds binding to analytes and/or modifying their activity. | 12-26-2013 |