Hollenbach, US
Andrew D. Hollenbach, New Orleans, LA US
Patent application number | Description | Published |
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20080248467 | System for pulling out regulatory elements using yeast - Disclosed are methods for identifying molecular interactions between DNA sequences and proteins in vivo. The methods of the invention employ known or suspected DNA-binding proteins and genomic DNA in a plasmid library. Interacting molecules direct the expression of a reporter gene, the expression of which is then assayed. Also disclosed are genetic constructs useful in practicing the methods of the invention. | 10-09-2008 |
20090298083 | Phospho-Specific Anti-Pax3 Antibodies - Pax3, a member of the paired class homeodomain family of transcription factors and an essential protein for early skeletal muscle development, was shown to be phosphorylated in proliferating mouse primary myoblasts. Furthermore, Ser205, Ser201 and Ser209 were identified as the only sites of phosphorylation on Pax3 in proliferating mouse primary myoblasts. Phosphorylation of Ser205 was shown to be required for the efficient phosphorylation of Ser201 and/or Ser209. Site-specific antibodies were made to each of these three sites when phosphorylated. These three sites are also present and phosphorylated in the Pax3-FOXO1 fusion protein, and phosphorylation of these sites may play a role in ARMS. Thus, these new antibodies may be used in studying the regulation of nerve and muscle development and differentiation and in finding therapeutic solutions for certain disorders, including Waardenburg syndrome and childhood solid muscle tumor alveolar rhabdomyosarcoma (ARMS). | 12-03-2009 |
Andrew D. Hollenbach US
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20080248958 | System for pulling out regulatory elements in vitro - Disclosed are methods for identifying molecular interactions between proteins and DNA sequences in vitro. All of the methods of the invention employ known or suspected DNA-binding proteins and genomic DNA from a stable library. Interacting molecules direct the expression of a reporter gene, the expression of which is then assayed. Also disclosed are genetic constructs useful in practicing the methods of the invention. | 10-09-2008 |
Daniel F. Hollenbach, Oak Ridge, TN US
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20090302983 | MAGNETIC FIELD SIMULATOR AND RELATED METHODS FOR SIMULATING THE EARTH'S MAGNETIC FIELD - Apparatus and methods for simulating the Earth's magnetic field. The apparatus includes a spherical structure having a rotational axis and a molten metal therewithin. A support is coupled to the spherical structure so that the spherical structure is rotatable about a rotational axis. Rotation of the spherical structure generates inertial forces in the molten metal. The apparatus may include one or more magnetometers operatively coupled to an outer surface of the spherical structure for measuring a magnetic field generated by the spherical structure. | 12-10-2009 |
20120114102 | X-RAY BACKSCATTER IMAGING OF NUCLEAR MATERIALS - The energy of an X-ray beam and critical depth are selected to detect structural discontinuities in a material having an atomic number Z of 57 or greater. The critical depth is selected by adjusting the geometry of a collimator that blocks backscattered radiation so that backscattered X-ray originating from a depth less than the critical depth is not detected. Structures of Lanthanides and Actinides, including nuclear fuel rod materials, can be inspected for structural discontinuities such as gaps, cracks, and chipping employing the backscattered X-ray. | 05-10-2012 |
20120183116 | COMPOSITE NUCLEAR FUEL PELLET - A composite nuclear fuel pellet comprises a composite body including a UO2 matrix and a plurality of high aspect ratio particies dispersed therein, where the high aspect ratio particies have a thermal conductivity higher than that of the UO2 matrix. A method of making a composite nuclear fuel pellet includes combining UO2 powder with a predetermined amount of high aspect ratio particles to form a combined powder, the high aspect ratio particles having a thermal conductivity higher than that of the UO2 powder; mixing the combined powder in a solvent to disperse the high aspect ratio particles in the UO2 powder; evaporating the solvent to form a dry mixture comprising the high aspect ratio particles dispersed in the UO2 powder; pressing the dry mixture to form a green body; and sintering the green body to form the composite fuel pellet. | 07-19-2012 |
David Allen Hollenbach, Marion, OH US
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20150153143 | Bullet Resistant Desktop - A bullet-resistant shield is described herein that attaches to existing student desks. The embodiment consists of a bullet-resistant repositionable desk top and height-adjustable bullet-resistant front shields. | 06-04-2015 |
John David Hollenbach, Raleigh, NC US
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20140278728 | System and Methods For Determining Risk of Supply Chain Disruption - Methods and systems for determining risk in a supply chain and displaying risk to a user. A supply chain is defined in a database by linking one or more driver components to a monitored component. Each driver component is associated with one or more component indicators that provide an indication of an expected availability of the driver component. Each component indicator is assigned a risk score. An expected risk value and a worst case risk value are determined for each component indicator. A risk profile is then determined based on a ratio between the expected risk values of the component indicators and the worst case risk values of the component indicators. The risk profile may then be displayed on a web page through a database portal. If the risk profile exceeds a threshold, the database may transmit a notification to a subscriber to the database. | 09-18-2014 |
John H. Hollenbach, Vienna, VA US
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20090062590 | Process for separating a heavy oil feedstream into improved products - This invention relates to a process for separating a heavy hydrocarbon stream to produce at least one permeate product stream and at least one retentate product stream. The process utilizes an ultrafiltration process to designed to maximize the quality of the permeate and retenate product streams as well as process embodiments which improve permeate production quantities as well as improve the quality of the product streams obtained by the separations process. In preferred embodiments, the process includes configuration and operational parameters to maximize permeate yield and selectivity. | 03-05-2009 |
Kate Hollenbach, Los Angeles, CA US
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20140195988 | OPERATING ENVIRONMENT COMPRISING MULTIPLE CLIENT DEVICES, MULTIPLE DISPLAYS, MULTIPLE USERS, AND GESTURAL CONTROL - Embodiments described herein includes a system comprising a processor coupled to display devices, sensors, remote client devices, and computer applications. The computer applications orchestrate content of the remote client devices simultaneously across at least one of the display devices and the remote client devices, and allow simultaneous control of the display devices. The simultaneous control includes automatically detecting a gesture of at least one object from gesture data received via the sensors. The gesture data is absolute three-space location data of an instantaneous state of the at least one object at a point in time and space. The detecting comprises aggregating the gesture data, and identifying the gesture using only the gesture data. The computer applications translate the gesture to a gesture signal, and control at least one of the display devices and the remote client devices in response to the gesture signal. | 07-10-2014 |
20150077326 | OPERATING ENVIRONMENT WITH GESTURAL CONTROL AND MULTIPLE CLIENT DEVICES, DISPLAYS, AND USERS - Embodiments described herein includes a system comprising a processor coupled to display devices, sensors, remote client devices, and computer applications. The computer applications orchestrate content of the remote client devices simultaneously across the display devices and the remote client devices, and allow simultaneous control of the display devices. The simultaneous control includes automatically detecting a gesture of at least one object from gesture data received via the sensors. The detecting comprises identifying the gesture using only the gesture data. The computer applications translate the gesture to a gesture signal, and control the display devices in response to the gesture signal. | 03-19-2015 |
Ned Hollenbach, Murfreesboro, AR US
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20100043271 | SCOPE MOUNTING SYSTEM - A scope mounting system having one or more components formed of a zinc alloy, preferably an alloy of zinc, aluminum, magnesium and copper. In one form, the component is formed of an alloy of zinc with about 3.5 to 4.3 weight percent aluminum, about 0.02 to 0.05 weight percent magnesium, and about 2.5 to 3.0 weight percent copper. The scope mounting system preferably includes one or more components, such as a base and/or rings, at least one of the components being formed by casting. | 02-25-2010 |
Ned J. Hollenbach, Murfreesboro, AR US
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20090133311 | UNIVERSAL SCOPE MOUNTING SYSTEM - A universal scope mounting system for a firearm includes an integral base/lower ring half component having a base panel portion and a split ring portion extending therefrom, and defining a plurality of mounting holes for receiving mounting screws to attach the base/lower ring half component to a firearm. The system also includes an upper ring half component for attachment to the base/lower ring half component to engage a scope within a receiver opening defined therebetween. The mounting holes of each base/lower ring half component define two or more different mounting hole configurations, permitting universal application to firearms having different scope mounting hole arrangements. | 05-28-2009 |
20100269396 | UNIVERSAL SCOPE MOUNT - A system and method for mounting a telescopic sight or “scope” to a firearm. The system is convertible or universal, in that it includes interchangeable mounting plate inserts allowing the mounting plate to be installed onto two or more different types of firearms having differing mounting hole configurations. | 10-28-2010 |
Paul Hollenbach, Castro Valley, CA US
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20100086518 | TREATMENT OF MELANOMA - Methods of treating melanoma include administering a compound of Structure I, a tautomer of the compound, a pharmaceutically acceptable salt of the compound, a pharmaceutically acceptable salt or the tautomer, or a mixture thereof to a subject. The compound, tautomer, salt of the compound, salt of the tautomer, or mixture thereof may be used to prepare medicaments for treating metastatic cancer. The variable A has the values defined herein. | 04-08-2010 |
Samuel J. Hollenbach, Baltimore, MD US
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20130077263 | Electronic Housing and Sensor Connection Arrangement - A garment includes a fabric portion, an electrode fixedly connected to the fabric portion, a receptacle fixedly connected to the fabric portion, and an electronics module releasably positioned in the receptacle. The receptacle includes a receptacle housing, an electrode lead, and a receptacle contact. The electrode lead is attached to the electrode. The electrode lead engages the receptacle contact to establish an electrical connection with the receptacle contact without being attached to the receptacle contact. The electronics module includes a module contact that engages the receptacle contact when the electronics module is positioned in the socket to establish an electrical connection between the module contact and the receptacle contact. | 03-28-2013 |
20140189928 | Garment with Receptacle and Electronic Module - A garment includes a fabric portion with an electrode connected to the fabric portion and configured to engage a torso of the wearer. A receptacle is fixedly connected to the fabric portion and includes a receptacle housing, a socket defined by the receptacle housing, and an electrode lead, the electrode lead extending through the receptacle housing and providing an electrical connection between the electrode and the socket. An electronics module is configured to be removably inserted into the socket of the receptacle and contact the electrode lead. The electronics module includes a multi-component injection molded housing including a front face having a first portion and a second portion. The first portion is comprised of a relatively soft and resilient polymer material and the second portion is comprised of a relatively hard and rigid polymer material. | 07-10-2014 |
Stanley J. Hollenbach, South San Francisco, CA US
Patent application number | Description | Published |
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20080254036 | COMBINATION ANTICOAGULANT THERAPY WITH A COMPOUND THAT ACTS AS A FACTOR XA INHIBITOR - The present invention is directed to methods of using combination therapies containing [2-({4-[(dimethylamino)iminomethyl]phenyl}carbonylamino)-5-methoxyphenyl]-N-(5-chloro(2-pyridyl))carboxamide for the treatment of thrombotic disease(s) and pharmaceutical compositions thereof. | 10-16-2008 |
20110015128 | UNIT DOSE FORMULATION OF ANTIDOTES FOR FACTOR XA INHIBITORS AND METHODS OF USING THE SAME - The present invention relates unit dose formulations of antidotes to anticoagulants targeting factor Xa. Disclosed herein are methods of stopping or preventing bleeding in a patient that is currently undergoing anticoagulant therapy with a factor Xa inhibitor. | 01-20-2011 |
20120046230 | Combination Anticoagulant Therapy With A Compound That Acts As A Factor Xa Inhibitor - The present invention is directed to methods of using combination therapies containing [2-({4-[(dimethylamino)iminomethyl]phenyl}carbonylamino)-5-methoxyphenyl]-N-(5-chloro(2-pyridyl))carboxamide for the treatment of thrombotic disease(s) and pharmaceutical compositions thereof. | 02-23-2012 |
20130315897 | Combination Anticoagulant Therapy With A Compound That Acts As A Factor Xa Inhibitor - The present invention is directed to methods of using combination therapies containing [2-({4-[(dimethylamino)iminomethyl]phenyl}carbonylamino)-5-methoxyphenyl]-N-(5-chloro(2-pyridyl))carboxamide for the treatment of thrombotic disease(s) and pharmaceutical compositions thereof. | 11-28-2013 |
20150025011 | UNIT DOSE FORMULATION OF ANTIDOTES FOR FACTOR XA INHIBITORS AND METHODS OF USING THE SAME - The present invention relates unit dose formulations of antidotes to anticoagulants targeting factor Xa. Disclosed herein are methods of stopping or preventing bleeding in a patient that is currently undergoing anticoagulant therapy with a factor Xa inhibitor. | 01-22-2015 |