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Hollenbach, US
Andrew D. Hollenbach, New Orleans, LA US
| Patent application number | Description | Published |
|---|---|---|
| 20080248467 | System for pulling out regulatory elements using yeast - Disclosed are methods for identifying molecular interactions between DNA sequences and proteins in vivo. The methods of the invention employ known or suspected DNA-binding proteins and genomic DNA in a plasmid library. Interacting molecules direct the expression of a reporter gene, the expression of which is then assayed. Also disclosed are genetic constructs useful in practicing the methods of the invention. | 10-09-2008 |
| 20090298083 | Phospho-Specific Anti-Pax3 Antibodies - Pax3, a member of the paired class homeodomain family of transcription factors and an essential protein for early skeletal muscle development, was shown to be phosphorylated in proliferating mouse primary myoblasts. Furthermore, Ser205, Ser201 and Ser209 were identified as the only sites of phosphorylation on Pax3 in proliferating mouse primary myoblasts. Phosphorylation of Ser205 was shown to be required for the efficient phosphorylation of Ser201 and/or Ser209. Site-specific antibodies were made to each of these three sites when phosphorylated. These three sites are also present and phosphorylated in the Pax3-FOXO1 fusion protein, and phosphorylation of these sites may play a role in ARMS. Thus, these new antibodies may be used in studying the regulation of nerve and muscle development and differentiation and in finding therapeutic solutions for certain disorders, including Waardenburg syndrome and childhood solid muscle tumor alveolar rhabdomyosarcoma (ARMS). | 12-03-2009 |
Andrew D. Hollenbach US
| Patent application number | Description | Published |
|---|---|---|
| 20080248958 | System for pulling out regulatory elements in vitro - Disclosed are methods for identifying molecular interactions between proteins and DNA sequences in vitro. All of the methods of the invention employ known or suspected DNA-binding proteins and genomic DNA from a stable library. Interacting molecules direct the expression of a reporter gene, the expression of which is then assayed. Also disclosed are genetic constructs useful in practicing the methods of the invention. | 10-09-2008 |
Daniel F. Hollenbach, Oak Ridge, TN US
| Patent application number | Description | Published |
|---|---|---|
| 20090302983 | MAGNETIC FIELD SIMULATOR AND RELATED METHODS FOR SIMULATING THE EARTH'S MAGNETIC FIELD - Apparatus and methods for simulating the Earth's magnetic field. The apparatus includes a spherical structure having a rotational axis and a molten metal therewithin. A support is coupled to the spherical structure so that the spherical structure is rotatable about a rotational axis. Rotation of the spherical structure generates inertial forces in the molten metal. The apparatus may include one or more magnetometers operatively coupled to an outer surface of the spherical structure for measuring a magnetic field generated by the spherical structure. | 12-10-2009 |
John H. Hollenbach, Vienna, VA US
| Patent application number | Description | Published |
|---|---|---|
| 20090062590 | Process for separating a heavy oil feedstream into improved products - This invention relates to a process for separating a heavy hydrocarbon stream to produce at least one permeate product stream and at least one retentate product stream. The process utilizes an ultrafiltration process to designed to maximize the quality of the permeate and retenate product streams as well as process embodiments which improve permeate production quantities as well as improve the quality of the product streams obtained by the separations process. In preferred embodiments, the process includes configuration and operational parameters to maximize permeate yield and selectivity. | 03-05-2009 |
Ned Hollenbach, Murfreesboro, AR US
| Patent application number | Description | Published |
|---|---|---|
| 20100043271 | SCOPE MOUNTING SYSTEM - A scope mounting system having one or more components formed of a zinc alloy, preferably an alloy of zinc, aluminum, magnesium and copper. In one form, the component is formed of an alloy of zinc with about 3.5 to 4.3 weight percent aluminum, about 0.02 to 0.05 weight percent magnesium, and about 2.5 to 3.0 weight percent copper. The scope mounting system preferably includes one or more components, such as a base and/or rings, at least one of the components being formed by casting. | 02-25-2010 |
Ned J. Hollenbach, Murfreesboro, AR US
| Patent application number | Description | Published |
|---|---|---|
| 20090133311 | UNIVERSAL SCOPE MOUNTING SYSTEM - A universal scope mounting system for a firearm includes an integral base/lower ring half component having a base panel portion and a split ring portion extending therefrom, and defining a plurality of mounting holes for receiving mounting screws to attach the base/lower ring half component to a firearm. The system also includes an upper ring half component for attachment to the base/lower ring half component to engage a scope within a receiver opening defined therebetween. The mounting holes of each base/lower ring half component define two or more different mounting hole configurations, permitting universal application to firearms having different scope mounting hole arrangements. | 05-28-2009 |
| 20100269396 | UNIVERSAL SCOPE MOUNT - A system and method for mounting a telescopic sight or “scope” to a firearm. The system is convertible or universal, in that it includes interchangeable mounting plate inserts allowing the mounting plate to be installed onto two or more different types of firearms having differing mounting hole configurations. | 10-28-2010 |
Paul Hollenbach, Castro Valley, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20100086518 | TREATMENT OF MELANOMA - Methods of treating melanoma include administering a compound of Structure I, a tautomer of the compound, a pharmaceutically acceptable salt of the compound, a pharmaceutically acceptable salt or the tautomer, or a mixture thereof to a subject. The compound, tautomer, salt of the compound, salt of the tautomer, or mixture thereof may be used to prepare medicaments for treating metastatic cancer. The variable A has the values defined herein. | 04-08-2010 |
Stanley J. Hollenbach, South San Francisco, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20080254036 | COMBINATION ANTICOAGULANT THERAPY WITH A COMPOUND THAT ACTS AS A FACTOR XA INHIBITOR - The present invention is directed to methods of using combination therapies containing [2-({4-[(dimethylamino)iminomethyl]phenyl}carbonylamino)-5-methoxyphenyl]-N-(5-chloro(2-pyridyl))carboxamide for the treatment of thrombotic disease(s) and pharmaceutical compositions thereof. | 10-16-2008 |
| 20110015128 | UNIT DOSE FORMULATION OF ANTIDOTES FOR FACTOR XA INHIBITORS AND METHODS OF USING THE SAME - The present invention relates unit dose formulations of antidotes to anticoagulants targeting factor Xa. Disclosed herein are methods of stopping or preventing bleeding in a patient that is currently undergoing anticoagulant therapy with a factor Xa inhibitor. | 01-20-2011 |