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Holladay, US

Adam Holladay, Salt Lake City, UT US

Patent application numberDescriptionPublished
20100318911SYSTEM FOR AUTOMATED GENERATION OF AUDIO/VIDEO CONTROL INTERFACES - A system for automating generation of an audio/video (AV) control interface includes a computing device having a processor to enable a user, with a user interface of the computing device, to configure the AV system. The processor may enable the user to draw output zones to create a representation of a geographical layout of a venue in which the AV system is located. The processor may enable the user to place transmitting and receiving AV devices within the output zones that substantially represent physical locations thereof within the venue. The processor may enable the user to logically associate receiving AV device channels of receiving AV devices within an output zone. The processor assigns parameters of the associated AV devices to a control interface for user control thereof. To do so, the processor identifies controllable parameters associated with the AV devices associated with the output zone. The processor assigns a data storage structure associated with each respective controllable parameter to the control interface. The processor launches the control interface in an application window having integrated therewith the controllable parameters and a menu selection of a source AV signal.12-16-2010
20100318917NETWORKED AUDIO/VIDEO SYSTEM - A system for configuring an audio/video (AV) system includes a computing device having a processor to enable a user, with a user interface of the computing device, to configure the AV system. The processor may enable the user to draw output zones to create a representation of a geographical layout of a venue in which the AV system is located. The processor may enable the user to place transmitting and receiving AV devices within the output zones that substantially represent physical locations thereof within the venue. The processor may enable the user to logically associate receiving AV device channels of one or more receiving AV devices within an output zone. The processor may also enable the user to select which of a number of source AV signals from transmitting AV devices the user wants to route to the associated output zone. The processor routes the source AV signals from one or more transmitting AV devices over a network to the one or more receiving AV device channels, such that the one or more receiving AV device channels are processed according to the output zone as configured by the user in the user interface.12-16-2010

Jack T. Holladay, Bellaire, TX US

Patent application numberDescriptionPublished
20090032679MULTI-FOCAL INTRAOCULAR LENS SYSTEM AND METHODS - The invention pertains to methods, components, and operations of multi-focal intraocular lens systems, including range finding for driving same and for discriminating between multiple objects and varying brightness conditions. The invention also pertains to intraocular photosensors and range-finding methods to be used with intra-ocular lens systems, and components, that provide multi-focal IOL capabilities in dynamic visual environments.02-05-2009
20100152847OPTICAL ANGULAR MEASUREMENT SYSTEM FOR OPHTHALMIC APPLICATIONS AND METHOD FOR POSITIONING OF A TORIC INTRAOCULAR LENS WITH INCREASED ACCURACY - An ophthalmic system for use in performing angular measurements in relation to a patient's eye. The ophthalmic system can include an optical angular measurement device that can provide angular indicia by, for example, projecting an image of an angular measurement reticle onto a patient's eye or by superimposing an image of an angular measurement reticle onto an image of the patient's eye. The ophthalmic system can include an optical refractive power measurement device for providing desired angular orientations for ocular implants or for incisions. The ophthalmic system can be used, for example, to align a toric intraocular lens to a desired angular orientation.06-17-2010
20110013141OPHTHALMIC SURGERY MEASUREMENT SYSTEM - An ophthalmic apparatus for measuring spatial distances within a patient's eye is disclosed. The apparatus can be used to measure, for example, the capsular bag depth in an aphakic eye. The spatial measurement system can direct laser light into a patient's eye so that a portion of the light is scattered by the capsular bag. The scattered light can be directed to a detector where spots can be formed corresponding to the locations on the capsular bag from which the light was scattered. The distance from the cornea to the capsular bag can be determined based, for example, at least in part on the distance between the spots formed on the detector. In some embodiments, the apparatus can include a surgical microscope and/or a wavefront aberrometer. In some embodiments, an alignment system can be used to precisely position the apparatus relative to the patient's eye. The ophthalmic apparatus can be used for variety of ophthalmic procedures, such as predicting the postoperative position of an intraocular lens (IOL) and determining appropriate optical power for the IOL.01-20-2011
20110015541DETERMINATION OF THE EFFECTIVE LENS POSITION OF AN INTRAOCULAR LENS USING APHAKIC REFRACTIVE POWER - An ophthalmic method for determining a relationship between aphakic ocular power and estimated effective lens position (ELP) of an intraocular lens (IOL) to be implanted in a patient's eye. The method can be used to determine an estimate of the ELP of an IOL given the aphakic ocular power of the patient's eye, for example, without measurement of the corneal curvature or axial length of the patient's eye. The estimate of ELP can then be used to determine a suitable value of optical power for the IOL to be implanted in the patient's eye.01-20-2011
20110213462Multi-Focal Intraocular Lens System and Methods - The invention pertains to methods, components, and operations of multi-focal intraocular lens systems, including range finding for driving same and for discriminating between multiple objects and varying brightness conditions. The invention also pertains to intraocular photosensors and range-finding methods to be used with intra-ocular lens systems, and components, that provide multi-focal IOL capabilities in dynamic visual environments.09-01-2011
20110255056ASTIGMATIC AXIS INDEPENDENT SPATIAL FREQUENCY AND CONTRAST SENSITIVITY TARGET AND METHOD - A set of visual targets and a method for using these targets to evaluate the spatial frequency response and contrast sensitivity of the human visual system. The invention includes four choice test, six choice test, sinusoidal bulls eye and fundamental sinusoidal letters or optotype targets. The four and six choice targets feature sinusoidal gratings oriented vertically, horizontally and at angles thereto. The sinusoidal bull's eye target features concentric circular light and dark areas with brightness varying in a radial sinusoidal fashion. The fundamental sinusoidal optotype target features an optotype, such as a letter, that is made up of strokes, each of which have a width that is equal to ½ of a single sinusoidal period.10-20-2011

Patent applications by Jack T. Holladay, Bellaire, TX US

Leslie A. Holladay, Mountain View, CA US

Patent application numberDescriptionPublished
20090275877Method of Enhancing Electrotransport Polypeptide Flux By Amino Acid Substitution with Histidine - Methods of modifying polypeptide drugs in order to enhance their transdermal electrotransport flux are provided. The polypeptide is modified by substituting a histidine residue (His) for one or more glutamine (Gln), threonine (Thr) and/or asparagine (Asn) residue(s). The His for Gln substitution is particularly preferred from the standpoint of retaining biological activity of the parent polypeptide. Compositions containing the modified polypeptide, which are useful for transdermal electrotransport delivery, are also provided.11-05-2009

Mark Holladay, San Diego, CA US

Patent application numberDescriptionPublished
20110269740JAK KINASE MODULATING COMPOUNDS AND METHODS OF USE THEREOF - Provided herein are pyrrolotriazine compounds for treatment of JAK kinase, including JAK2 kinase mediated diseases. Also provided are pharmaceutical compositions comprising the compounds and methods of using the compounds and compositions.11-03-2011

Mark W. Holladay, San Diego, CA US

Patent application numberDescriptionPublished
20090030008PIPERAZINE DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS - Methods of treating an SCD-mediated disease or condition in a mammal, preferably a human, are disclosed, wherein the methods comprise administering to a mammal in need thereof a compound of formula (I):01-29-2009
20090131447COMBINATION THERAPY - This invention is directed to the use of SCD-1 inhibitors of the formula (I): where x, y, V, W, G, J, L, M, R2, R3, R5, R5a, R6, R6a, R7, R7a, R8 and R8a are defined herein, in combination with other drug therapies to treat adverse weight gain.05-21-2009
20100317659JAK KINASE MODULATING COMPOUNDS AND METHODS OF USE THEREOF - Provided herein are quinazoline compounds for treatment of JAK kinase mediated diseases, including JAK2 kinase-, JAK3 kinase- or TYK2 kinase-mediated diseases. Also provided are pharmaceutical compositions comprising the compounds and methods of using the compounds and compositions.12-16-2010
20110118245RAF KINASE MODULATOR COMPOUNDS AND METHODS OF USE THEREOF - Compounds according to formula (I), compositions and methods are provided for modulating the activity of RAF kinases, including BRAF kinase and for the treatment, prevention, or amelioration of one or more symptoms of disease or disorder mediated by RAF kinases. Formula (I): or a pharmaceutically acceptable salt, solvate, clathrate of hydrate thereof, wherein X is O or S(O)05-19-2011

Patent applications by Mark W. Holladay, San Diego, CA US

Montie W. Holladay, College Station, TX US

Patent application numberDescriptionPublished
20110094345Sucker Rod Coupling Extractor - A prior art sucker rod tong is improved to remove a coupling completely from a sucker rod assembly comprising sucker rods joined end to end by couplings. The prior art sucker rod tong has a rotatable jaw assembly and a lower backup wrench adapted to cooperate to unscrew a coupling joining first and second rods, where the coupling remains screwed to the second rod after it is unscrewed from the first rod. The improvement comprises a coupling extractor for unscrewing the coupling from the second rod so that the coupling can be replaced. The coupling extractor comprises a shaft having an extractor end portion on each end of the shaft and a shield around each extractor end portion, wherein the coupling extractor is designed and sized to fit within and to be rotated by the jaw assembly. The extractor end portion engages the inside wall of the coupling to unscrew the coupling from the second rod. The extractor end portion is preferably a tapered, left-handed spiral fluted easy-out extractor. The improvement preferably further comprises an upper backup wrench movably connected to the sucker rod tong for holding the second sucker rod when the second sucker rod is above the coupling.04-28-2011
20110094346Sucker Rod Coupling Extractor - A prior art sucker rod tong is improved to remove a coupling completely from a sucker rod assembly comprising sucker rods joined end to end by couplings. The prior art sucker rod tong has a rotatable jaw assembly and a lower backup wrench adapted to cooperate to unscrew a coupling joining first and second rods, where the coupling remains screwed to the second rod after it is unscrewed from the first rod. The improvement comprises a coupling extractor for unscrewing the coupling from the second rod so that the coupling can be replaced. The coupling extractor comprises a shaft having an extractor end portion on each end of the shaft and a shield around each extractor end portion, wherein the coupling extractor is designed and sized to fit within and to be rotated by the jaw assembly. The extractor end portion engages the inside wall of the coupling to unscrew the coupling from the second rod. The extractor end portion is preferably a tapered, left-handed spiral fluted easy-out extractor. The improvement preferably further comprises an upper backup wrench movably connected to the sucker rod tong for holding the second sucker rod when the second sucker rod is above the coupling.04-28-2011

Robert J. Holladay, Saratoga, UT US

Patent application numberDescriptionPublished
20110262556SILVER/WATER, SILVER GELS AND SILVER-BASED COMPOSITIONS; AND METHODS FOR MAKING AND USING THE SAME - We disclose a colorless composition comprising metal particles (e.g., silver nanoparticles) and water, wherein said particles comprise an interior of elemental metal (e.g., silver) and an exterior of metal oxide (e.g., one or more silver oxide(s)), wherein the metal nanoparticles are present in the water at a level of about 5-40 ppm, and wherein the composition manifests significant antimicrobial properties. Methods of use of the composition are described. The composition can be incorporated into a hydrogel with essentially no loss of antimicrobial properties. Various metal-containing compositions with unexpected biological efficacy are also disclosed.10-27-2011