Holden, GB
Andrew Holden, Lancashire GB
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20110230590 | POLYMERIC MATERIALS - Granules or pellets comprising polymeric materials such as polyaryletherketones and ceramic materials may be prepared and used to make a variety of different parts of components for use in medical applications, by melt-processing. The ceramic material may be a bioactive glass and/or a controlled-release glass, and may include less than 20 mole % sodium oxide and/or be water soluble. | 09-22-2011 |
Benjamin J. Holden, Herts GB
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20090173346 | DOSE COUNTER - This application discloses a dose counter for use in connection with a device adapted for metered dispensing of a medication. The dose counter has a first count indicator that has a first indicia bearing surface, with the first count indicator being rotatable about a first axis. The dose counter also has a second count indicator that has a second indicia bearing surface, with the second count indicator being rotatable about a second axis. The second axis is disposed at an obtuse angle with respect to the first axis, and the first and second indicia bearing surfaces align at a common viewing area to collectively present at least a portion of a medication dosage count. | 07-09-2009 |
20130291861 | DOSE COUNTER - A dose counter for use in connection with a device adapted for metered dispensing of a medication is described. The dose counter has a first count indicator that has a first indicia bearing surface, with the first count indicator being rotatable about a first axis. The dose counter also has a second count indicator that has a second indicia bearing surface, with the second count indicator being rotatable about a second axis. The second axis is disposed at an obtuse angle with respect to the first axis, and the first and second indicia bearing surfaces align at a common viewing area to collectively present at least a portion of a medication dosage count. | 11-07-2013 |
Carren Holden, Bristol GB
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20100004769 | METHOD OF DESIGNING A STRUCTURE - A method of designing a structure, such as an airfoil section. A first set of candidate designs is generated in a first optimisation process, each candidate design comprising a set of M design variables associated with an M-dimensional design space. A subset of the first set of candidate designs is selected. The selected subset of candidate designs is analysed by proper orthogonal decomposition or principal component analysis to generate an N-dimensional design space defined by N design variables, N being less than M. A second set of one or more candidate designs is then generated in a second optimisation process, each candidate design comprising a set of N design variables associated with the N-dimensional design space. | 01-07-2010 |
20100318327 | METHOD OF DESIGN OPTIMISATION - A method of design optimization includes: a) producing a first computer model of a first geometry, the first computer model including: i) a set of nodes; and ii) a set of construction points each having a position defined by a local co-ordinate system; b) producing a computational fluid dynamics (CFD) mesh from the first computer model; c) using the CFD mesh to produce a measure of the fluid dynamic performance of the first geometry, such as drag count or lift coefficient; d) producing a new computer model of a new geometry by: i) moving one or more of the nodes; and ii) recalculating the positions of the construction points in response to movement of the one or more nodes; e) producing a computational fluid dynamics (CFD) mesh from the new computer model; f) using the CFD mesh to produce a measure of the fluid dynamic performance of the new geometry, such as drag count or lift coefficient; and g) identifying an optimal geometry using the fluid dynamic performance measurements of the first and new geometries produced in steps c and f. | 12-16-2010 |
Christopher James Holden, London GB
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20130125301 | TOILET - A toilet, wherein: the toilet has an aperture ( | 05-23-2013 |
David Holden, Greater Manchester GB
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20100129669 | FIRE RESISTANT GLAZING - The incorporation of polyvalent metal ions into a silicate based interlayer in a laminated fire resistant glazing produced using a cast in place process provides an improvement in the properties of those glazings. The preferred metal ions are aluminium ions and zirconium ions. The preferred polyvalent metal compounds are those which are disclosed in EP 1206349 and WO 2004/014813. | 05-27-2010 |
David Holden, Wigan GB
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20110183145 | METHOD FOR THE PRODUCTION OF FIRE RESISTANT GLAZINGS - Fire resistant glazings having improved properties comprising a silicate based interlayer which contains from 35% to 43% by weight of water may be produced using a cast in place process. The amount of water in the interlayer is reduced by concentrating the silicate solution or by introducing silica in the form of a silica sol. Preferably a mixture of an aqueous sol and an organosol is used. Polyhydroxy compounds and saccharides may be incorporated into the interlayer to improve the properties thereof and to reduce the water content. The silicate based formulations are pourable and can be used in a cast in place production process and subsequently cured to form an optically clear interlayer. | 07-28-2011 |
20120061008 | Method for the Production of Fire Resistant Glazing - Fire resistant glazings having improved properties comprising a silicate based interlayer which contains from 35% to 43% by weight of water may be produced using a cast in place process. The amount of water in the interlayer is reduced by concentrating the silicate solution or by introducing silica in the form of a silica sol. Preferably a mixture of an aqueous sol and an organosol is used. Polyhydroxy compounds and saccharides may be incorporated into the interlayer to improve the properties thereof and to reduce the water content. The silicate based formulations are pourable and can be used in a cast in place production process and subsequently cured to form an optically clear interlayer. | 03-15-2012 |
20140360652 | Method for the Production of Fire Resistant Glazings - Fire resistant glazings having improved properties comprising a silicate based interlayer which contains from 35% to 43% by weight of water may be produced using a cast in place process. The amount of water in the interlayer is reduced by concentrating the silicate solution or by introducing silica in the form of a silica sol. Preferably a mixture of an aqueous sol and an organosol is used. Polyhydroxy compounds and saccharides may be incorporated into the interlayer to improve the properties thereof and to reduce the water content. The silicate based formulations are pourable and can be used in a cast in place production process and subsequently cured to form an optically clear interlayer. | 12-11-2014 |
David Holden, Derbyshire GB
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20100147894 | LOCK-OUT DEVICE AND METHOD - A method and device to insure that a particular dispensing package ( | 06-17-2010 |
20110073622 | METERING AND DISPENSING CLOSURE - A metering and dispensing closure for a container wherein two rotatable disks rotate in conjunction with a stationary cap member to afford accurate measuring of a powder material and dispensing of it. The disks and the container cap afford a consistent measuring of the powder material, as well as provide a variety of drive members which can be utilized with the dispensing closure. | 03-31-2011 |
20110220684 | METERING AND DISPENSING CLOSURE - A metering and dispensing closure for a container. A rotor and a movable member rotate in conjunction with a cap member to afford accurate measuring of a powder material and dispensing of it. The rotor, the movable member, and the container cap afford a consistent measuring of the powder material, as well as provide a variety of drive members which can be utilized with the dispensing closure. | 09-15-2011 |
20130062347 | METERING AND DISPENSING CLOSURE - A metering and dispensing closure for a container wherein two rotatable disks rotate in conjunction with a stationary cap member to afford accurate measuring of a powder material and dispensing of it. The disks and the container cap afford a consistent measuring of the powder material, as well as provide a variety of drive members which can be utilized with the dispensing closure. | 03-14-2013 |
20130098945 | METERING AND DISPENSING CLOSURE - A metering and dispensing closure for a container. A rotor and a movable member rotate in conjunction with a cap member to afford accurate measuring of a powder material and dispensing of it. The rotor, the movable member, and the container cap afford a consistent measuring of the powder material, as well as provide a variety of drive members which can be utilized with the dispensing closure. | 04-25-2013 |
20150329348 | LOCK-OUT DEVICE AND METHOD - A method and device to insure that a particular dispensing package ( | 11-19-2015 |
David J. Holden, Derbyshire GB
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20120298700 | LIQUID DISPENSNG CONTAINER AND METHOD - A liquid dispenser including a container that has an interior adapted to support a fluid. The liquid dispenser includes an air vent that is coupled to the container, and a balloon that is disposed in the container and in fluid communication with the air vent to provide fluid communication between the interior and an exterior of the container. The balloon is movable from an undeployed state to a deployed state in response to a pressure change between the interior and the exterior of the container. The balloon in the undeployed state is incapable of fluid communication between the interior and the exterior of the container, and the balloon in the deployed state has a position in which the balloon establishes fluid communication between the exterior of the container and the interior of the container. | 11-29-2012 |
David William Holden, Berkshire GB
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20080274139 | Attenuated microorganisms for the treatment of infection - The present invention pertains to a | 11-06-2008 |
David William Holden, Wigan GB
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20090317618 | Fire Resistant Glazing - Fire resistant glazings comprise a fire resistant interlayer based upon a silicate waterglass are characterised by the incorporation of aluminium ions. The aluminate is incorporated as a solution which has been partially neutralised using hydroxycarboxylic acid which is preferably citric acid. The incorporation of aluminium provides glazings have improved fire resistance and impact properties. | 12-24-2009 |
20120076966 | LAMINATED GLAZING - A fire-resistant laminated glazing comprising at least two glazing panes and at least one transparent intumescent interlayer between the glazing panes, said glazing panes being separated by a spacer extending at least partially around their peripheries so as to define a cavity to contain said interlayer, wherein the spacer comprises a shim for controlling the separation between the glazing panes to a predetermined distance and a rubber portion at least partially enclosing the shim, and wherein the interlayer comprises an alkali metal silicate. | 03-29-2012 |
20120205600 | FIRE RESISTANT GLAZINGS - A stable aqueous solution for the production of fire resistant glazings comprising: at least one alkali metal silicate; and an aqueous solution of at least one alkali-soluble anion of an acidic or amphoteric oxide and/or a complex thereof; and/or at least one alkali-soluble hydroxide, and/or alkali-soluble complex of elements selected from the group consisting of lithium, magnesium and calcium. | 08-16-2012 |
20120208921 | FIRE RESISTANT GLAZING - A transparent fire resistant glazing comprising an intumescent interlayer, wherein the intumescent interlayer comprises an alkali metal silicate and a foam improvement additive, wherein the foam improvement additive comprises a polymer and/or oligomer and/or salts thereof, wherein said polymer, oligomer and/or salts thereof each contain at least one organic moiety having at least one hydrogen-bondable functional group covalently attached thereto. | 08-16-2012 |
David William Holden, London GB
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20090280141 | Streptococcal Genes - Peptides derived from | 11-12-2009 |
20110229515 | IDENTIFICATION OF GENES - A method for identifying a microorganism having a reduced adaptation to a particular environment comprising the steps of: | 09-22-2011 |
David William Holden, Greater Manchester GB
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20120292824 | Fire Resistant Glazings - Bilayer materials are produced by drying a solution of an alkali metal silicate upon the surface of a flexible backing material until a flexible silicate film is produced. The film may be separated from the backing material and incorporated into laminated fire resistant glazings. The alkali metal silicate solution preferably comprise a surfactant. The bilayers may be transported or stored before the flexible silicate film is separated and incorporated into a glazing. | 11-22-2012 |
David William Holden, Orrell GB
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20150056456 | FIRE RESISTANT GLAZINGS - An aqueous mixture for the production of fire resistant glazings comprising: at least one alkali metal silicate, at least one glass, glass-ceramic and/or ceramic additive, and water, wherein the at least one glass, glass-ceramic and/or ceramic additive has at least one boron containing moiety directly or indirectly attached to a surface thereof by covalent or ionic bonding. | 02-26-2015 |
Derek John Holden, Blackburn GB
Harriet Ann Holden, Britstol GB
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20100126140 | MILLIMETRE-SCALE ENGINE - A millimetre-scale pulse jet engine comprises an engine body that defines a combustion chamber, a fuel, an air intake, and an exhaust. The fuel inlet is arranged to inject fuel directly into the combustion chamber. The air intake and the exhaust are in fluid communication with the combustion chamber, and the combustion chamber is configured such that air from the air intake and fuel from the fuel inlet cyclically combust in the combustion chamber to produce exhaust gases. | 05-27-2010 |
Harriet Ann Holden, Cambridge GB
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20110226675 | PARTICLE SEPARATORS - A particle separator stage in a particle separator includes an inflow passage of generally annular, axially facing form. In other embodiments, an asymmetric geometry is disclosed in which the major flow is taken from one side only. These features combine to allow compact, multi-stage separators to be produced. Also disclosed an arrangement in which the flow rate at a location within the separator stage is measured and used to control the flow rate there or elsewhere. | 09-22-2011 |
Ian G. Holden, Salisbury GB
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20110004867 | AUTOMATED LEVEL-BASED TARGETED TEST CONFIGURATION - An indication of a change to at least one source file associated with a software build is received via a processor. A set of test levels of a level-based testing suite are sequentially processed, where each test level subsequently processed includes tests with decreasing qualitative testing information relative to tests associated with previously-processed test levels. For each processed test level, at least one test is selected that tests the change to the at least one source file associated with the software build, test coverage relative to a target risk level for the software build is determined for each selected test, and test selection is terminated upon determining that the test coverage for the selected tests at least meets the target risk level for the software build. | 01-06-2011 |
20120192159 | AUTOMATED LEVEL-BASED TARGETED TEST CONFIGURATION - An indication of a change to at least one source file associated with a software build is received via a processor. A set of test levels of a level-based testing suite are sequentially processed, where each test level subsequently processed includes tests with decreasing qualitative testing information relative to tests associated with previously-processed test levels. For each processed test level, at least one test is selected that tests the change to the at least one source file associated with the software build, test coverage relative to a target risk level for the software build is determined for each selected test, and test selection is terminated upon determining that the test coverage for the selected tests at least meets the target risk level for the software build. | 07-26-2012 |
Ian G. Holden, Wiltshire GB
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20120260255 | Dynamic Test Scheduling - According to one embodiment of the present invention, a system dynamically schedules performance of tasks, and comprises a computer system including at least one processor. The system determines resources required or utilized by each task for performance of that task on a target system, and compares the determined resources of the tasks to identify tasks with similar resource requirements. The identified tasks with similar resource requirements are scheduled to be successively performed on the target system. Embodiments of the present invention further include a method and computer program product for dynamically scheduling performance of tasks in substantially the same manner described above. | 10-11-2012 |
John Holden, Purley-On-Thames GB
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20130324110 | METHOD OF PROCESSING NETWORK CONFIGURATION DATA - A method and system for comparing network configuration data stored in a wireless communication network with parameters that depend on the physical configuration of the network is provided. Subscriber wireless communication devices operating in the network provide measurement data. From the measurement data, at least one first parameter is selected or derived, the first parameter depending on the physical configuration of the network. From network configuration data stored in the wireless communication network, at least one second parameter that corresponds to the at least one first parameter is selected. Any discrepancy between the values of the first and second parameters is then identified. Analysis of the discrepancies may reveal errors or omissions in the stored network configuration data, such as missing entries in the neighbors table for a cell site. Faults in the physical network may also be revealed. | 12-05-2013 |
Martin Holden, Grantchester GB
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20150028196 | FIELD ASYMMETRIC ION MOBILITY SPECTROMETRY FILTER - Ion filter for FAIMS fabricated using the LIGA technique. The ion filter is manufactured using a metal layer to form the ion channels and an insulating support layer to hold the structure rigidly together after separation of the metal layer into two electrodes. | 01-29-2015 |
Matthew Holden, Oxford GB
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20100032627 | FORMATION OF BILAYERS OF AMPHIPATHIC MOLECULES - A method of forming bilayers of amphipathic molecules uses droplets of aqueous solution in a hydrophobic medium such as oil. A layer of amphipathic molecules such as a lipid is formed around the surfaces of the droplets. This may be achieved by providing the lipid in the oil and leaving the droplets for a time sufficient to form the layer. The droplets are brought into contact with one another so that a bilayer of the amphipathic molecules is formed as an interface between the contacting droplets. The bilayers may be used for a wide range of studies. The technique has numerous advantages including providing a long lifetime for the bilayers, allowing study of small volumes and allowing the construction of chains and networks of droplets with bilayers in between to study complex systems. | 02-11-2010 |
20130146815 | FORMATION OF BILAYERS OF AMPHIPATHIC MOLECULES - A method of forming bilayers of amphipathic molecules uses droplets of aqueous solution in a hydrophobic medium such as oil. A layer of amphipathic molecules such as a lipid is formed around the surfaces of the droplets. This may be achieved by providing the lipid in the oil and leaving the droplets for a time sufficient to form the layer. The droplets are brought into contact with one another so that a bilayer of the amphipathic molecules is formed as an interface between the contacting droplets. The bilayers may be used for a wide range of studies. The technique has numerous advantages including providing a long lifetime for the bilayers, allowing study of small volumes and allowing the construction of chains and networks of droplets with bilayers in between to study complex systems. | 06-13-2013 |
Paula Thomson Holden, Wiltshire GB
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20100266639 | Expression system - An immunogenic reagent which produces an immune response which is protective against | 10-21-2010 |
Paula Thomson Holden, Salisbury GB
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20130164823 | Expression System - An immunogenic reagent which produces an immune response which is protective against | 06-27-2013 |
Paul Stephen Holden, Sheffield GB
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20080200586 | Dental/Surgical Sealants Including Shapeable Particles - A sealant composition, suitable for surgical or dental use, comprises a sealant and, dispersed therein, one or more particles of a material which is prestressed and/or capable of undergoing expansion or contraction. | 08-21-2008 |
Peter Geoffrey Holden, Cirencester GB
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20090072130 | Rotary Encoder Apparatus and Method - Rotary encoder apparatus is described that comprises an encoder scale or ring and an encoder scale reader. The encoder scale includes an incremental scale and one or more reference marks. The encoder scale reader comprises at least a first readhead and a second readhead that each produce a reference mark signal when passed over a reference mark of the encoder scale. The apparatus also comprises a reference position setter for determining, as the encoder scale reader is rotated relative to the encoder scale, at least one angularly repeatable reference position of the encoder scale relative to the encoder scale reader using a first reference mark signal produced by the first readhead and second reference mark signal subsequently produced by the second readhead. | 03-19-2009 |
Philip Holden, Edinburgh GB
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20150350439 | REMOTE ASSISTANCE CUSTOMER INFORMATION - A customer operating a device requests remote assistance from a remote assistance center. A remote assistance interface executing on the device interacts with a remote assistance manager to provide the customer with information relevant to receiving remote assistance in a time and manner acceptable to the customer and based on customer navigation and selection of options associated with the information. | 12-03-2015 |
Roger Holden, Bristol GB
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20080319557 | Program-Controlled Process - A drilling machine drills at a multiplicity of target locations on a component. Two robots, calibrated with calibration data, move the component in a 6-D coordinate system. A metrology system ascertains the position of the component relative to the drilling machine. The movement of the robots is effected by means of commands generated by means of off-line programming. The component is moved relative to the drilling machine to a target position, ready for drilling, by means of a closed-loop process in which the differences in position between the expected position (the target position) and the actual position (as viewed by the metrology system) are corrected. | 12-25-2008 |
Steven Hedley Holden, Cumbria GB
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20120129748 | DOSAGE FORM DETERGENT PRODUCTS - A method of producing a dosage form detergent product, comprises the steps of: (a) producing an open-mouthed pouch by forming a water-soluble, synthetic plastics film into a mould cavity defining said pouch, (b) introducing a particulate first detergent composition into the pouch, (c) forming a recess in the upper surface of the particulate first detergent composition, (d) introducing into said recess a pre-formed, shape-retaining second detergent component with an at least substantially planar face positioned to be exposed from the particulate first detergent component, and (e) sealing a water-soluble film over the mouth of the pouch and against said exposed face of the pre-formed detergent product. | 05-24-2012 |
Timothy Holden, Cambridge GB
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20100087470 | Buprenorphine-Wafer for Drug Substitution Therapy - The present invention relates to oral pharmaceutical dosage forms comprising buprenorphine with the dosage form releasing buprenorphine instantly upon oral, preferably sublingual, application of the dosage form. The present invention also relates to the use of such dosage forms for treating pain in a human or animal or for drug substitution therapy in drug-dependent human subjects. | 04-08-2010 |
20150025102 | Buprenorphine-Wafer for Drug Substitution Therapy - The present invention relates to oral pharmaceutical dosage forms comprising buprenorphine with the dosage form releasing buprenorphine instantly upon oral, preferably sublingual, application of the dosage form. The present invention also relates to the use of such dosage forms for treating pain in a human or animal or for drug substitution therapy in drug-dependent human subjects. | 01-22-2015 |
20150328143 | Buprenorphine-Wafer for Drug Substitution Therapy - The present invention relates to oral pharmaceutical dosage forms comprising buprenorphine with the dosage form releasing buprenorphine instantly upon oral, preferably sublingual, application of the dosage form. The present invention also relates to the use of such dosage forms for treating pain in a human or animal or for drug substitution therapy in drug-dependent human subjects. | 11-19-2015 |