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Hofland
Adriaan Hofland, Zwolle NL
| Patent application number | Description | Published |
|---|---|---|
| 20100048812 | WATER-DISPERSIBLE, AIR-DRYING URALKYD RESINS - A water-dispersible, air-drying uralkyd resin comprising the reaction product of a) of at least one fatty acid modified polyester polyol comprising components i) at least one unsaturated C | 02-25-2010 |
| 20110064933 | AQUEOUS EMULSION COATING COMPOSITION COMPRISING AN AUTOXIDISABLE FATTY ACID MODIFIED POLYESTER - An aqueous coating composition comprising an autoxidisable fatty acid modified polyester resin having ≧40 wt % of fatty acid residues; a Tg in the range of from −70 to +20° C.; an acid value less than 40 mg KOH/g; a Mw in the range of from 5,000 to 125,000 g/mol; >5 wt % of ring structures; and said composition having a co-solvent content less than 20 wt % by weight of solids; a solids content >38 wt %; and when in the form of the film having a telegraphing value of less than 35 gloss units. | 03-17-2011 |
Gerard W. Hofland, Hoogmade NL
| Patent application number | Description | Published |
|---|---|---|
| 20100260891 | Dehydration Method - The present invention relates to a method of dehydrating pieces of intact plant or animal tissue, said pieces containing at least 30 wt. % of water, the method comprising (i) contacting the pieces of intact tissue with a pressurised gas to reduce the water content of the pieces by at least 50%, said pressurised gas having a pressure of at least 0.5×P | 10-14-2010 |
Gerard Willem Hofland, Hoogmade NL
| Patent application number | Description | Published |
|---|---|---|
| 20080213380 | Process for the Preparation of Encapsulates Through Precipitation - A process for the preparation of encapsulates, employs: a pumpable emulsion having (i) a continuous phase containing a solvent and a matrix-forming solute dissolved in the solvent and (ii) a dispersed phase; an extractant including supercritical, subcritical or liquefied gas; the solvent being substantially more soluble in the extractant than the matrix-forming solute and the process including the successive steps of: a) combining the pumpable emulsion with the extractant under mixing conditions; b) allowing the formation of particulate encapsulates in which the dispersed phase is encased in a solid matrix of the matrix-forming solute; c) collecting the encapsulates and separating them from the extractant. The present processes is particularly suitable for producing particles containing active ingredients that are very sensitive, whose activity is adversely affected by exposure to oxygen, light, moisture, heat and/or friction. | 09-04-2008 |
| 20110171349 | MICROENCAPSULATE AND PROCESS FOR THE MANUFACTURE THEREOF - The present invention relates to a microencapsulate comprising microcapsules having a diameter of 0.1 μm to 25 μm, said microcapsules comprising: —a core particle having a diameter of 90 nm to 23 μm and containing at least 3% of the active component by weight of said core particle; and—a coating that fully envelops the core particle and containing at least 20 wt. % of a hydrophobic polymer selected from cellulosic ethers, cellulosic esters, zein, shellac, gluten, polylactide, hydrophobic starch derivatives, polyvinyl acetate polymers, polymers or copolymers derived from an acrylic acid ester and/or a methacrylic acid ester and combinations thereof; wherein the core particle contains a release trigger component and/or the coating contains a release trigger component, said release trigger component being selected from: —a water-swellable polymer having a water-uptake capacity at 37° C. and pH 7.0 of less than 20 wt. % and a water-uptake capacity at 37° C. and pH 2.0 of at least 50 wt. %; an—an edible salt having a water solubility at 37° C. and a pH of 7.0 of less than 1 mg/ml and a water solubility at 37° C. and a pH of 2.0 of at least 5 mg/ml; The microencapsulate of the present invention does not release the encapsulated active component when incorporated in water-containing foodstuffs, beverages, nutritional compositions or pharmaceutical compositions. Following ingestion, however, the active component is released rapidly. | 07-14-2011 |
Gerard Willem Hofland, Weesp NL
| Patent application number | Description | Published |
|---|---|---|
| 20100184744 | METHOD OF PREPARING A PHARMACEUTICAL CO-CRYSTAL COMPOSITION - The present invention relates to a method of preparing a pharmaceutical co-crystal composition, said method comprising the steps of: a. simultaneously contacting a supercritical or liquefied gas with solid particles of a pharmaceutically active component and with solid particles of a co-builder to form a co-crystallisation medium containing dissolved pharmaceutically active component and dissolved co-builder as well as solid particles of the pharmaceutically active component and solid particles of the co-builder; b. transforming the solid particles of the pharmaceutically active component and the solid particles of the co-builder into co-crystals of said pharmaceutically active component and said co-builder by keeping the supercritical or liquefied gas in a supercritical or liquid state until at least 80 wt. % of the pharmaceutically active component is incorporated in the crystal matrix of said co-crystals; and c. separating said co-crystals from the supercritical or liquefied gas wherein at least a fraction of the pharmaceutically active component and at least a fraction of the co-builder remain in an undissolved state during the co-crystallisation. The present method enables easy preparation of a pharmaceutical co-crystal composition containing virtually no solvent residue and can suitably be used to prepare co-crystals of highly labile pharmaceutically active components. | 07-22-2010 |
Gregg S. Hofland, Parker, CO US
| Patent application number | Description | Published |
|---|---|---|
| 20110125407 | Apparatus and Method for Integrating Survey Parameters into a Header - A method, apparatus and system for acquiring seismic data is disclosed that in one aspect receives a seismic signal detected by at least one sensor in response to a seismic energy signal generated by a source at a selected location at a data acquisition unit in data that is in data communication with the sensor, receives at least one parameter of the source and/or receiver at the data acquisition unit; and generates a data block at the data acquisition unit having data representative of the received seismic signal and a header that contains data representative of the at least one parameter of the source and/or receiver. It is emphasized that this abstract is provided to comply with the rules requiring an abstract which will allow a searcher or other reader to quickly ascertain the subject matter of the technical disclosure. It is submitted with the understanding that it will not be used to interpret or limit the scope or meaning of the claims. | 05-26-2011 |
Hans Hofland, Research Triangle Park, NC US
| Patent application number | Description | Published |
|---|---|---|
| 20120128612 | AZOLE ANTIFUNGAL COMPOSITIONS - The present invention relates generally to antifugal compositions. In an embodiment, the antifungal compositions are effective for application to nails and surrounding skin, and comprise at least one volatile solvent, at least one film forming substance, and at least one pyrimidone derivative of formula I, such as albaconazole. These compositions are capable of treating an infection caused by fungi, such as onychomychosis. | 05-24-2012 |
Hans Hofland, Palo Alto, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20110305646 | FATTY ACID MONOGLYCERIDE COMPOSITIONS - The present invention relates to a method of treating a fungal condition caused by | 12-15-2011 |
| 20120115909 | TAZAROTENE DERIVATIVES - The presently described subject matter relates to new derivatives of tazarotene that also exhibit retinoid activity, pharmaceutical compositions comprising the derivatives, method of treating skin disorders with the pharmaceutical compositions, and process of making the derivatives. | 05-10-2012 |
Hans E.j. Hofland, Foster City, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20090196914 | LIPOSOMAL L-CARNITINE - The present invention provides liposomal L-carnitine formulations and methods for the treatment of intermittent claudication. The formulation is optimized with respect to L-carnitine transport through skin in vitro. Preferably, the formulation is a topical cream for the administration of the drug directly on the muscle group that is most affected by the poor local blood flow. | 08-06-2009 |
Leendert Johannes Hofland, Rotterdam NL
| Patent application number | Description | Published |
|---|---|---|
| 20100093614 | Novel Composition for Tumor Growth Control - The invention describes a pharmaceutical composition comprising at least compound selected from the group of demethylating agents and HDAC inhibitors and at least one somatostatin analog or dopamine agonist for the treatment of a tumor which expresses a somatostatin and/or dopamine receptor. | 04-15-2010 |