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Hoey, US

Gee Sun Hoey, Fremont, CA US

Patent application numberDescriptionPublished
20100329827LINEAR VACUUM ROBOT WITH Z MOTION AND ARTICULATED ARM - There is described apparatus and methods for transporting and processing substrates including wafers as to efficiently produce at reasonable costs improved throughput as compared to systems in use today. A linear transport chamber includes linear tracks and robot arms riding on the linear tracks to linearly transfer substrates along the sides of processing chambers for feeding substrates into a controlled atmosphere through a load lock and then along a transport chamber as a way of reaching processing chambers. A four-axis robot arm is disclosed, capable of linear translation, rotation and articulation, and z-motion.12-30-2010

John G. Hoey, Elmer, NJ US

Patent application numberDescriptionPublished
20100209936Novel recombinant 15-kDa polypeptide and use of same in detecting human infection with Bartonella henselae - Disclosed are the cloning and expression of a novel antigen of 08-19-2010
20110053189Type IV secretion system proteins in sero-detection of Anaplasma phagocytophium - Disclosed are two (2) proteins in the Type IV Secretion System (TIVSS) in 03-03-2011
20110076699Hemolysin and its protein fragments in sero-detection of anaplasma phagocytophilum - Disclosed is the cloning, expression and purification of a hemolysin protein and its protein fragments in 03-31-2011
20110143377Protein fragments of virB10 and sero-detection of anaplasma phagocytophium - Disclosed are cloning and expression of a plurality of protein fragments of virB10, a Type IV Secretion System (TIVSS) in 06-16-2011
20110306062Babesia microti genomic clones containing novel antigens useful in the diagnosis of babesios - Disclosed are the cloning and expression of novel antigens in 12-15-2011

Justin Michael Hoey, Fargo, ND US

Patent application numberDescriptionPublished
20090053507CONVERGENT-DIVERGENT-CONVERGENT NOZZLE FOCUSING OF AEROSOL PARTICLES FOR MICRON-SCALE DIRECT WRITING - A Convergent-Divergent-Convergent nozzle apparatus for direct-write applications is described. The tip apparatus includes at least three nozzles concentrically positioned in series. In a non-limiting embodiment, a first nozzle has a converging taper, a second nozzle extends from the first nozzle with a diverging taper, and a third nozzle extends from the second nozzle and has a converging taper. The nozzles are positioned in series and are coaxial, and can be formed from either separate components or a monolithic structure. Such an arrangement has permitted direct writing of aerosolized particle streams in line widths from 3.7-8 μm in width prior to sintering. Further refinements to the apparatus and processing parameters may result in line widths of 1 μm or less. Aerosolized particles may comprise conductor or semiconductor precursors that may be processed into microelectronic conductors or semiconductors, respectively. The particles may also comprise nanostructures or nanoparticles.02-26-2009

Michael Hoey, Maplewood, NJ US

Patent application numberDescriptionPublished
20120035088LUBRICANT COMPOSITION HAVING IMPROVED ANTIWEAR PROPERTIES - The instant invention provides a lubricant composition having improved four-ball antiwear properties. The lubricant composition includes a base oil and one or more alkylethercarboxylic acid corrosion inhibitor(s) having the formula:02-09-2012

Michael Hoey US

Patent application numberDescriptionPublished
20110313312Tissue Discrimination and Applications in Medical Procedures - A system and method for discriminating tissue types, controlling the level of therapy to tissue, and determining the health of a known tissue by measuring the characteristics of an electrical signal applied to a conductive element located within or by the tissue. Additionally, the system and method may be used for determining whether the conductive tip of a pedicle probe or pedicle screw is located in one of cortical bone, cancellous bone, and cortical bone near a boundary with soft tissue, whether the conductive tip of a cannula is located adjacent to one of nerve tissue and annulus tissue, and whether the conductive tip of a cathode is located adjacent to one of nerve tissue and prostate gland tissue.12-22-2011

Michael Dennis Hoey, Maplewood, NJ US

Patent application numberDescriptionPublished
20090011966Lubricating Oil Composition - A lubricating oil composition having a total base number of more than 15 mg KOH/g, as determined by ASTM D2896, and including at least 40 mass % of an oil of lubricating viscosity; at least one detergent; and at least one compound of the formula (I) and/or formula (II):01-08-2009

Michael F. Hoey US

Patent application numberDescriptionPublished
20100049081Tissue Discrimination and Applications in Medical Procedures - A system and method for discriminating tissue types, controlling the level of therapy to tissue, and determining the health or a known tissue by measuring the characteristics an electrical signal applied to conductive element located within or by the tissue. Additionally, the system and method may be used for determining whether the conductive tip of a pedicle probe or pedicle screw is located in one of cortical bone, cancellous bone, and cortical bone near a boundary with soft tissue, whether the conductive tip of a cannula is located adjacent to one of nerve tissue and annulus tissue, and whether the conductive tip of a cathode is located adjacent to one of nerve tissue and prostate gland tissue.02-25-2010

Michael F. Hoey, Shoreview, MN US

Patent application numberDescriptionPublished
20080300593Method of Ablating Tissue - An electrocautery device is disclosed. In accordance with one aspect of the invention, the electrocautery electrode/tip is provided with a hollow, conductive tube terminating at its distal end in a ball point type tip. Fluid, preferably conductive fluid, is applied to the proximal end of the hollow electrode/tip, and expelled from the distal end thereof during electrocautery. The ball point distal tip allows the distal tip to be directly applied to the tissue and “rolled” or slid along the tissue. This allows the distal tip to be moved across the tissue without dragging or snagging on the tissue. In addition, the conductive fluid expelled from the distal tip further lubricates the distal tip as it moves across the tissue. If conductive fluid is used, the conductive fluid emanating from the electrode/tip conducts the RF electrocautery energy away from the distal tip so that it is primarily the fluid, rather than the distal tip that actually accomplishes the cauterizing of tissue. That is, the fluid serves as a “virtual” electrocautery electrode. Since it is the fluid, rather than the distal tip that cauterizes, coagulates and ablates, no burns or perforations are made to the tissue, reducing the amount of debris at the site. Also, the flow of fluid through the electrode/tip tends to keep the distal tip clean and cool.12-04-2008
20090189618METHOD, SYSTEM, AND APPARATUS FOR LIQUID MONITORING, ANALYSIS, AND IDENTIFICATION - Embodiments of liquid monitoring, analysis, and identification are described generally herein. Other embodiments may be described and claimed.07-30-2009
20100076299Inducing Desirable Temperature Effects On Body Tissue Using Alternate Energy Sources - A system for inducing desirable temperature effects on body tissue, the body tissue being disposed about a lumen. The system includes an elongate catheter having a proximal end and a distal end with an axis therebetween with an energy delivery portion for transmission of energy. A tissue analyzer configured to characterize the body tissue in the lumen proximate the energy delivery portion and an energy source coupled to the energy delivery portion transmitting tissue treatment energy, wherein the energy is non-RF energy. A processor coupled to the tissue analyzer and energy source, the processor configured to determine an appropriate treatment energy for the characterized body tissue so as to mildly heat the body tissue with the energy delivery portion without ablating.03-25-2010
20100168743Tuned RF energy for selective treatment of atheroma and other target tissues and/or structures - A catheter and catheter system can use energy tailored for remodeling and/or removal of target material along a body lumen, often of atherosclerotic material of a blood vessel of a patient. An elongate flexible catheter body with a radially expandable structure may have a plurality of electrodes or other electrosurgical energy delivery surfaces to radially engage atherosclerotic material when the structure expands. An atherosclerotic material detector system may measure and/or characterize the atherosclerotic material and its location, optionally using impedance monitoring.07-01-2010
20110130708Directional Delivery of Energy and Bioactives - Systems and methods are disclosed for the treatment of a target tissue by directionally delivering energy and/or bioactive materials to achieve a therapeutic effect. A balloon catheter system having a balloon portion and a plurality of electrodes may be energized to selectively deliver energy, bioactive materials, or a combination thereof to target tissue including tissues disposed about a lumen. The tissue may be targeted by applying energy, making tissue impedance analysis, and further selectively energizing electrodes through the use of an energy source with a controller.06-02-2011

Patent applications by Michael F. Hoey, Shoreview, MN US

Thomas J. Hoey, Amherst, NH US

Patent application numberDescriptionPublished
20090150989USER AUTHENTICATION - A device, method, and system disclosed herein may be used to integrate and control authentication and passwords among various applications and platforms. The exemplary method may obtain a service ticket from a key distribution center of the key distribution center authentication process and generate a random key. A port between the client and the service may be created and utilized to transmit the service ticket and the random key to a service from the client. The random key may replace a password provided by the user. The random key in the password field of the service logon is transmitted to the service. The service authenticates the random key in the password field with the stored random key in the cache of the service. Once authenticated the service ticket is validated.06-11-2009
20090150991PASSWORD GENERATION - A device, method and system for authentication by a user are disclosed herein. The exemplary method may authenticate a user password entered by a user. User specific attributes may be accessed and used to produce a generated password. The generated password may be produced using an algorithm and the user attributes. The generated password may be used to log onto a resource for the user.06-11-2009

Tim Hoey, Hillsborough, CA US

Patent application numberDescriptionPublished
20100169990COMPOSITIONS AND METHODS FOR TREATING AND DIAGNOSING CANCER - The present invention relates to compositions and methods for characterizing, treating and diagnosing cancer. In particular, the present invention provides a cancer stem cell profile, as well as novel stem cell cancer markers useful for the diagnosis, characterization, prognosis and treatment of cancer and in particular the targeting of solid tumor stem cells.07-01-2010
20100316637Compositions and Methods for Diagnosing and Treating Cancer - An isolated antibody that specifically binds to an extracellular domain of human DLL4 and affects growth of a tumor comprising cancer stem cells is described. Also described is a method of treating cancer comprising administering a therapeutically effective amount of an anti-DLL4 antibody.12-16-2010

Timothy Hoey, Hillsborough, CA US

Patent application numberDescriptionPublished
20080317760Compositions and Methods for Diagnosing and Treating Cancer - Monoclonal antibodies that specifically bind to an extracellular domain of human Jagged 1 and inhibit growth of a tumor comprising cancer stem cells are described. Also described is a method of treating cancer that comprises administering a therapeutically effective amount of a monoclonal anti-Jagged 1 antibody.12-25-2008
20100317098Compositions and Methods for Diagnosing and Treating Cancer - The present invention relates to compositions and methods for characterizing, diagnosing, and treating cancer. In particular the invention provides the means and methods for the diagnosis, characterization, prognosis and treatment of cancer and specifically targeting cancer stem cells. The present invention provides a soluble FZD receptor comprising an extracellular domain of a human FZD receptor that inhibits growth of tumor cells. The present invention still further provides a soluble receptor comprising a Fri domain of a human FZD receptor that binds a ligand of a human FZD receptor and said soluble receptor is capable of inhibiting tumor growth. The present invention still further provides a method of treating cancer comprising administering a soluble FZD receptor comprising for example, either an extracellular domain of a human FZD receptor or a Fri domain of a human FZD receptor, in an amount effective to inhibit tumor growth.12-16-2010
20110195065Compositions and Methods for Diagnosing and Treating Cancer - The present invention relates to compositions and methods for characterizing, diagnosing, and treating cancer. In particular the invention provides the means and methods for the diagnosis, characterization, prognosis and treatment of cancer and specifically targeting cancer stem cells. The present invention provides an antibody that specifically binds to a non-ligand binding region of the extracellular domain of a human NOTCH receptor and inhibits growth of tumor cells. The present invention further provides a method of treating cancer, the method comprising administering a therapeutically effective amount of an antibody that specifically binds to a non-ligand binding region of the extracellular domain of a human NOTCH receptor protein and inhibits growth of tumor cells.08-11-2011
20110311552NOTCH1 RECEPTOR BINDING AGENTS AND METHODS OF USE THEREOF - Means and methods for the diagnosis, characterization, prognosis and treatment of cancer, specifically targeting cancer stem cells are disclosed Provided is an antibody that specifically binds to a non-ligand binding membrane proximal region of the extracellular domain of a human Notch receptor and inhibits tumor growth, and a method of treating cancer comprising administering said antibody to a subject.12-22-2011

Patent applications by Timothy Hoey, Hillsborough, CA US

Timothy C. Hoey, Hillsborough, CA US

Patent application numberDescriptionPublished
20110165162Methods for Treating Cancers Comprising K-ras Mutations - Methods of inhibiting tumor growth, methods of treating cancer, and methods of reducing the frequency of cancer stem cells in a tumor are described. Particularly, the methods are directed to tumors or cancers that comprise a K-ras mutation. The methods described comprise administering a DLL4 antagonist (e.g., an antibody that specifically binds the extracellular domain of human DLL4) to a subject. Related polypeptides and polynucleotides, compositions comprising the DLL4 antagonists, and methods of making the DLL4 antagonists are also described.07-07-2011

Timothy Charles Hoey, Hillsborough, CA US

Patent application numberDescriptionPublished
20100104574Frizzled-Binding Agents and Uses Thereof - Novel anti-cancer agents, including, but not limited to, antibodies, that bind to human frizzled receptors are provided. Novel epitopes within the human frizzled receptors which are suitable as targets for anti-cancer agents are also identified. Methods of using the agents or antibodies, such as methods of using the agents or antibodies to inhibit Wnt signaling and/or inhibit tumor growth are further provided.04-29-2010
20100111958Notch-Binding Agents and Antagonists and Methods of Use Thereof - The present invention relates to Notch-binding agents and Notch antagonists and methods of using the agents and/or antagonists for treating diseases such as cancer. The present invention provides antibodies that specifically bind to a non-ligand binding region of the extracellular domain of one or more human Notch receptor, such as Notch2 and/or Notch3, and inhibit tumor growth. The present invention further provides methods of treating cancer, the methods comprising administering a therapeutically effective amount of an antibody that specifically binds to a non-ligand binding region of the extracellular domain of a human Notch receptor protein and inhibits tumor growth.05-06-2010
20110318341FRIZZLED-BINDING AGENTS AND USES THEREOF - Novel anti-cancer agents, including, but not limited to, antibodies, that bind to human frizzled receptors are provided. Novel epitopes within the human frizzled receptors which are suitable as targets for anti-cancer agents are also identified. Methods of using the agents or antibodies, such as methods of using the agents or antibodies to inhibit Wnt signaling and/or inhibit tumor growth are further provided.12-29-2011