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Hoeflich
Klaus Hoeflich, San Mateo, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20090098135 | COMBINATIONS OF PHOSPHOINOSITIDE 3-KINASE INHIBITOR COMPOUNDS AND CHEMOTHERAPEUTIC AGENTS, AND METHODS OF USE - Combinations of PI3K inhibitor compounds having Formulas I and II and chemotherapeutic agents, including stereoisomers, geometric isomers, tautomers, metabolites and pharmaceutically acceptable salts thereof, are useful for treating hyperproliferative disorders such as cancer. Methods of using such combinations for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed. | 04-16-2009 |
Klaus Hoeflich, South San Francisco, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20110223619 | COMBINATIONS OF PHOSPHOINOSITIDE 3-KINASE INHIBITOR COMPOUNDS AND CHEMOTHERAPEUTIC AGENTS, AND METHODS OF USE - Combinations of PI3K inhibitor compounds having Formulas I and II and chemotherapeutic agents, including stereoisomers, geometric isomers, tautomers, metabolites and pharmaceutically acceptable salts thereof, are useful for treating hyperproliferative disorders such as cancer. Methods of using such combinations for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed. | 09-15-2011 |
Klaus P. Hoeflich, Millbrae, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20100034836 | COMPOSITIONS AND METHODS FOR THE DIAGNOSIS AND ALLEVIATION OF TUMOR - The present invention is directed to methods of determining the presence of certain tumor-associated kinase polypeptides in a biological sample, and to compositions useful for the diagnosis and treatment of tumors in mammals | 02-11-2010 |
| 20110086837 | COMBINATIONS OF A PI3K INHIBITOR AND A MEK INHIBITOR - The invention relates methods of treating a patient with locally advanced or metastatic solid tumors with a combination of an inhibitor of phosphatidylinositol 3-kinase (PI 3-kinase or PI3K) and an inhibitor of mitogen activated protein kinase (MEK) described herein. | 04-14-2011 |
Klaus P. Hoeflich, San Mateo, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20080220471 | Vectors and Methods Using Same - The present invention is directed to vectors and to methods of using same. | 09-11-2008 |