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Hoeben
Dagmar Theo Coleta Maria Hoeben, Mol BE
| Patent application number | Description | Published |
|---|---|---|
| 20080280922 | Intermittent Dosing Regimen For Overweight and Obese Subjects - The present invention concerns an intermittent dosing regimen for the treatment of obesity or the reduction of body weight wherein a pharmaceutical composition containing an apoB secretion/MTP inhibitor is administered to a subject in need thereof for a period of time, then withheld for a period of time, and again administered for a period of time. The intermittent regimen may be repeated depending on the response in the subject that is being sought. | 11-13-2008 |
Robert C. Hoeben, Leiden NL
| Patent application number | Description | Published |
|---|---|---|
| 20090023196 | Stocks of replication-deficient adenovirus - Presented are ways to address the problem of replication-competent adenovirus in adenoviral production for use with, for example, gene therapy. Packaging cells having no overlapping sequences with a selected vector are suited for large scale production of recombinant adenoviruses. A system for use with the invention produces replication-defective adenovirus. The system includes a primary cell containing a nucleic acid based on or derived from adenovirus and an isolated recombinant nucleic acid molecule for transfer into the primary cell. The isolated recombinant nucleic acid molecule is based on or derived from an adenovirus, has at least one functional encapsidation signal and at least one functional Inverted Terminal Repeat, and lacks overlapping sequences with the nucleic acid of the cell. Otherwise, the overlapping sequences would enable homologous recombination leading to replication-competent adenovirus in the primary cell into which the isolated recombinant nucleic acid molecule is to be transferred. | 01-22-2009 |
| 20100240737 | ENZYME-PRODRUG THERAPY FOR PROSTHETIC JOINT REPAIR - The invention relates to the use of gene therapy in the treatment of aseptic loosening of orthopaedic prostheses and discloses methods of refixing such prostheses without open revision surgery. In particular, it provides adenoviral vectors and prodrugs for simultaneous, separate or sequential use in the destruction of interface tissue allowing subsequent recementing of loose prostheses in a minimally invasive manner. | 09-23-2010 |
Robert Cornelis Hoeben, Leiden NL
| Patent application number | Description | Published |
|---|---|---|
| 20100278863 | Reoviruses - The present invention provides a reverse genetics system for viruses belonging to the Reoviridae (i.e. Reoviruses), various uses thereof, genetically modified Reoviruses, Reovirus selection/production and propagation systems, medicaments and vaccines. | 11-04-2010 |
Wilhelmus Frederik Hoeben, Eindhoven NL
| Patent application number | Description | Published |
|---|---|---|
| 20090014624 | PORTABLE ILLUMINATION DEVICE - The present invention relates to a portable illumination device ( | 01-15-2009 |
Wilhelmus Frederik Laurens Maria Hoeben, Eindhoven NL
| Patent application number | Description | Published |
|---|---|---|
| 20080198009 | Security Lighting System and Method, and Control Unit Therefore - The present invention provides a security lighting system and method, that are intended to dispel and/or affect unwanted humans or animals ( | 08-21-2008 |
| 20100047138 | REACTIVE OXYGEN SPECIES GENERATOR, WASHING DEVICE AND WASHING METHOD - The invention relates to a reactive oxygen species (ROS) generator ( | 02-25-2010 |
Wilhelmus Johannes Franciscus Hoeben, Deurne NL
| Patent application number | Description | Published |
|---|---|---|
| 20100093507 | DEVICE HAVING A ROTATIONAL ELEMENT FOR FORMING SLEEVE-LIKE FOIL ENVELOPES - The invention relates to a device for forming sleeve-like foil envelopes from a continuous flat strip of a sleeve-like foil material, comprising supply means ( | 04-15-2010 |