Ho, NY
David Ho, New York, NY US
Patent application number | Description | Published |
---|---|---|
20120121597 | FUSION PROTEINS FOR HIV THERAPY - Disclosed herein are fusion antibodies created to provide both an antigen-binding site that targets the CD4 receptor and an antigen-binding site that targets the HIV envelope. The fusion antibodies disclosed herein provide improved potency and breadth against HIV as compared to monospecific antibodies, and additionally provide high barrier against viral resistance. Also disclosed are pharmaceutical formulations and therapeutic methods utilizing such fusion proteins. | 05-17-2012 |
David D. Ho, New York, NY US
Patent application number | Description | Published |
---|---|---|
20100041740 | FLU VACCINES AND METHODS OF USE THEREOF - This disclosure is directed, inter alia, to polynucleotides, polypeptides, vectors, cells and compositions comprising the same, and their use in affecting viral pathogenesis, in particular for influenza viral infection. | 02-18-2010 |
20110086053 | Glycolipids And Analogues Thereof As Antigens For NKT Cells - This invention relates to immunogenic compounds which serve as ligands for NKT (natural killer T) cells and to methods of use thereof in modulating immune responses. | 04-14-2011 |
20120258142 | GLYCOLIPIDS AND ANALOGUES THEREOF AS ANTIGENS FOR NKT CELLS - This invention relates to immunogenic compounds which serve as ligands for NKT (natural killer T) cells and to methods of use thereof in modulating immune responses. | 10-11-2012 |
20140186378 | GLYCOLIPIDS AND ANALOGUES THEREOF AS ANTIGENS FOR NKT CELLS - This invention relates to immunogenic compounds which serve as ligands for NKT (natural killer T) cells and to methods of use thereof in modulating immune responses. | 07-03-2014 |
David D. Ho, Chappaqua, NY US
Patent application number | Description | Published |
---|---|---|
20080318204 | Highly-Sensitive Genomic Assays Employing Chimeric Bacteriophage Standards - Methods are provided for sensitively quantitating at least one pre-selected DNA sequence in a biological sample utilizing hybridization methodology, the method employing as an internal standard an infectious bacteriophage particle comprising a detectable target DNA sequence other than that present in the pre-selected DNA sequence or in DNA quantitated from the biological sample, and as an external standard, an infectious bacteriophage particle comprising at least the pre-selected DNA sequence. | 12-25-2008 |
20090060949 | Flu vaccines and methods of use thereof - This disclosure is directed, inter alia, to polynucleotides, polypeptides, vectors, cells and compositions comprising the same, and their use in affecting viral pathogenesis, in particular for influenza viral infection. | 03-05-2009 |
20140248295 | GLYCAN-MODIFIED ANTI-CD4 ANTIBODIES FOR HIV PREVENTION AND THERAPY - Disclosed herein are glycan-modified anti-CD4 monoclonal antibodies with N-linked glycans attached to the variable region. Expression vectors and cell lines useful for the production of such antibodies, and use of such antibodies for HIV prevention and therapy are also disclosed. | 09-04-2014 |
20150152167 | HIV-1-NEUTRALIZING ANTIBODY POTENCY AND BREADTH VIA CELL RECEPTOR ANCHORING USING BISPECIFIC ANTIBODIES WITH NATIVE ARCHITECTURE - In various embodiments, the present invention relates generally to using bispecific antibodies in the prevention and treatment of HIV. | 06-04-2015 |
Gingtoe Ho, Brooklyn, NY US
Patent application number | Description | Published |
---|---|---|
20110247570 | Device for Teaching a Child to Walk - A device for allowing a trainer to help a child learn to walk, comprising: a child vest adapted to be worn on the upper torso of the child, having a pair of shoulder portions covering a pair of corresponding shoulder areas of the child, when the child vest is worn; an adjustable trainer belt for securing around the waist of the trainer; and a pair of adjustable shoulder strap assemblies respectively connecting the pair of shoulder portions of the child vest to the adjustable trainer belt. The device allows the trainer, typically, an adult, to support the child without engaging the trainer's hands or the child's hands and allows the trainer to remain in a full upright position to avoid strain on the lower back. | 10-13-2011 |
Herbert L. Ho, Cornwall, NY US
Patent application number | Description | Published |
---|---|---|
20090158234 | VERTICAL SOI TRENCH SONOS CELL - A semiconductor memory device and a design structure including the semiconductor memory device embodied in a machine readable medium is provided. In particular the present invention includes a semiconductor memory device in which a vertical trench semiconductor-oxide-nitride-oxide-semiconductor (SONOS) memory cell is created in a semiconductor-on-insulator (SOI) substrate is provided that allows for the integration of dense non-volatile random access memory (NVRAM) cells in SOI-based complementary metal oxide semiconductor (CMOS) technology. The trench is processed using conventional trench processing and it is processed near the beginning of the inventive method that allows for the fabrication of the memory cell to be fully separated from SOI logic processing. | 06-18-2009 |
20140021585 | CREATING DEEP TRENCHES ON UNDERLYING SUBSTRATE - A semiconductor structure and method of fabricating the same are disclosed. In an embodiment, the structure includes a first substrate having a buried plate or plates in the substrate. Each buried plate includes at least one buried plate contact, and a plurality of deep trench capacitors disposed about the at least one buried plate contact. A first oxide layer is disposed over the first substrate. The deep trench capacitors and buried plate contacts in the first substrate may be accessed for use in a variety of memory and decoupling applications. | 01-23-2014 |
20150214244 | STRUCTURE AND PROCESS TO DECOUPLE DEEP TRENCH CAPACITORS AND WELL ISOLATION - Formation of deep trench capacitors and isolation structures are decoupled by completing the isolation structures prior to etching trenches for capacitors and forming capacitors therein or vice-versa. Such decoupling of the formation of these respective structures allows different materials to be used in the deep trench capacitors and the isolation structures such as use of low permeability or dielectric constant materials and/or low Young's modulus materials in isolation structures to provide reduced AC capacitive coupling across isolation structures and/or relief of stresses associated with use of high dielectric constant materials or metal-insulator-metal (MIM) structures in deep trench capacitors. Such decoupling also allows increased efficiency of use of reaction chambers for the deep trench capacitors and the isolation structures. | 07-30-2015 |
Herbert L. Ho, Hopewell Junction, NY US
Patent application number | Description | Published |
---|---|---|
20110042731 | STRUCTURE AND METHOD OF FORMING ENHANCED ARRAY DEVICE ISOLATION FOR IMPLANTED PLATE EDRAM - A method for forming a memory device in a semiconductor on insulator substrate is provided, in which a protective oxide that is present on the sidewalls of the trench protects the first semiconductor layer, i.e., SOI layer, of the semiconductor on insulator substrate during bottle etching of the trench. In one embodiment, the protective oxide reduces back channel effects of the transistors to the memory devices in the trench that are formed in the semiconductor on insulator substrate. In another embodiment, a thermal oxidation process increases the thickness of the buried dielectric layer of a bonded semiconductor on insulator substrate by oxidizing the bonded interface between the buried dielectric layer and at least one semiconductor layers of the semiconductor on insulator substrate. The increased thickness of the buried dielectric layer may reduce back channel effects in devices formed on the substrate having trench memory structures. | 02-24-2011 |
20120108050 | WORK FUNCTION ENGINEERING FOR EDRAM MOSFETS - Embedded DRAM MOSFETs including an array NFET having a gate stack comprising a high-K dielectric layer upon which is deposited a first metal oxide layer (CD | 05-03-2012 |
Herbert Lei Ho, New Windsor, NY US
Patent application number | Description | Published |
---|---|---|
20090283840 | METAL GATE INTEGRATION STRUCTURE AND METHOD INCLUDING METAL FUSE, ANTI-FUSE AND/OR RESISTOR - A semiconductor structure and a method for fabricating the semiconductor structure provide a field effect device located and formed upon an active region of a semiconductor substrate and at least one of a fuse structure, an anti-fuse structure and a resistor structure located and formed at least in part simultaneously upon an isolation region laterally separated from the active region within the semiconductor substrate. The field effect device includes a gate dielectric comprising a high dielectric constant dielectric material and a gate electrode comprising a metal material. The at least one of the fuse structure, anti-fuse structure and resistor structure includes a pad dielectric comprising the same material as the gate dielectric, and optionally, also a fuse, anti-fuse or resistor that may comprise the same metal material as the gate electrode. | 11-19-2009 |
20140191366 | High-K and Metal Filled Trench-Type EDRAM Capacitor with Electrode Depth and Dimension Control - Partial removal of organic planarizing layer (OPL) material forms a plug of OPL material within an aperture that protects underlying material or electronic device such as a deep trench capacitor during other manufacturing processes. The OPL plug thus can absorb any differences or non-uniformity in, for example, etch rates across the chip or wafer and preserve recess dimensions previously formed. control of a lateral component of later removal of the OPL plug by etching also can increase tolerance of overlay error in forming connections and thus avoid loss in manufacturing yield. | 07-10-2014 |
20150102463 | HIGH-K AND METAL FILLED TRENCH-TYPE EDRAM CAPACITOR WITH ELECTRODE DEPTH AND DIMENSION CONTROL - Partial removal of organic planarizing layer (OPL) material forms a plug of OPL material within an aperture that protects underlying material or electronic device such as a deep trench capacitor during other manufacturing processes. The OPL plug thus can absorb any differences or non-uniformity in, for example, etch rates across the chip or wafer and preserve recess dimensions previously formed. control of a lateral component of later removal of the OPL plug by etching also can increase tolerance of overlay error in forming connections and thus avoid loss in manufacturing yield. | 04-16-2015 |
20150145102 | Methods for Deep Trench MIM Capacitor Moat Isolation with N+ Epitaxial Semiconductor Wafer Scheme - An integrated circuit structure provides at least one metal-insulator-metal (MIM) capacitor and a moat isolation structure wherein the number of processes required is substantially minimized and the formation of the MIM capacitor and the moat isolation structure effectively decouple while the number of processes common to the moat isolation structure and the MIM capacitor are maximized. Additional required processes are non-critical and tolerant of overlay positioning error. | 05-28-2015 |
Herbert Lei Ho, Hopewell Junction, NY US
Patent application number | Description | Published |
---|---|---|
20120248522 | DRAM WITH SCHOTTKY BARRIER FET AND MIM TRENCH CAPACITOR - A semiconductor circuit and method of fabrication is disclosed. In one embodiment, the semiconductor circuit comprises a metal-insulator-metal trench capacitor in a silicon substrate. A field effect transistor is disposed on the silicon substrate adjacent to the metal-insulator-metal trench capacitor, and a silicide region is disposed between the field effect transistor and the metal-insulator-metal trench capacitor. Electrical connectivity between the transistor and capacitor is achieved without the need for a buried strap. | 10-04-2012 |
20130099354 | CAPACITOR WITH DEEP TRENCH ION IMPLANTATION - An improved semiconductor capacitor and method of fabrication is disclosed. Embodiments utilize a deep trench which is then processed by performing a pre-amorphous implant on the trench interior to transform the interior surface of the trench to amorphous silicon which eliminates the depletion region that can degrade capacitor performance. | 04-25-2013 |
Ion Ho, Rochester, NY US
Patent application number | Description | Published |
---|---|---|
20160104081 | DYNAMIC SPACE-TIME DIAGRAM FOR VISUALIZATION OF TRANSPORTATION SCHEDULE ADHERENCE - A method for generating a visual representation of transport schedule adherence in a transit system including collecting transport schedule data received by a plurality of sensors deployed in a plurality of transit vehicles of the transit system, organizing and saving the received transport schedule data to a data storage facility, and receiving a user selection for the generation of a visual representation of transport schedule adherence in the transit system. The method may further include, by a transportation system analysis module, extracting a portion of the transport schedule data from the data storage facility and using the extracted transport schedule data to generate and display a dynamic space time diagram of transport schedule adherence in response to the user selection, automatically generating aggregated statistics and inference based on the dynamic space time diagram, and automatically generating a suggestion for improving transport schedule adherence based on the aggregated statistics and inferences. | 04-14-2016 |
Johnson Ho, Glen Cove, NY US
Patent application number | Description | Published |
---|---|---|
20110319975 | Methods for Reducing Discomfort During Electrostimulation, and Compositions and Apparatus Therefor - An electrode assembly for neuro-cranial stimulation includes an electrode, a conductive gel, and an adapter including an interior compartment for positioning the electrode relative to the adapter and for receiving and retaining the conductive gel. The conductive gel contacts the electrode along an electrode-gel interface. An orifice at one end of the interior compartment and adjacent to a positioning surface of the adapter for positioning the electrode assembly against a skin surface of a user enables the conductive gel is able to contact the skin surface of the user to define a gel-skin interface, such that a minimum distance between the electrode-gel interface and the gel-skin interface is maintained between 0.25 cm and 1.3 cm. An electrode assembly mounting apparatus is provided for adjustably positioning a plurality of electrode assemblies against target positions on the cranium. | 12-29-2011 |
Johny Ho, Brooklyn, NY US
Patent application number | Description | Published |
---|---|---|
20130068638 | APPARATUS, SYSTEMS AND METHODS FOR PROVIDING PORTABLE STORAGE FOR MULTIPLE USERS - Apparatus, systems and methods for providing portable storage for multiple users are disclosed. The portable storage systems may be used to accommodate the storage needs of multiple users. The portable storage solutions provide the capability to individuals to store relatively small quantities of materials off-site for a fixed or an undetermined amount of time, and are designed such that, in most instances, the materials are returned to the user at the same or different location when they are desired. The portable storage apparatus, systems and methods are cost-effective and provide a consumer with more flexibility than standard storage options. | 03-21-2013 |
Kenneth C. Ho, Yorktown Heights, NY US
Patent application number | Description | Published |
---|---|---|
20090167948 | System and Method for Selective Image Capture, Transmission and Reconstruction - A video processing method and system for generating a foveated video display with sections having different resolutions uses a network channel for communicating video images having video sections of different resolutions, and includes a video transmission system for processing and transmitting the received video images over the network channel. The system assigns a larger portion of the network channel's bandwidth to a video section with higher resolution. Further, the system includes a video receiving system for receiving and seamlessly combining the first and second video sections of different resolutions to form an output video image on a display device, and a control unit for sending one or more video control parameters to the video transmission system to control capturing, transmitting and processing of the video images. | 07-02-2009 |
Lap Ho, New York, NY US
Patent application number | Description | Published |
---|---|---|
20110111072 | METHODS FOR PREVENTING AND TREATING NEURODEGENERATIVE DISEASES - The present invention provide a method for the prevention and treatment of a neurodegenerative disease including Alzheimer's Disease, Huntington's Disease, and Parkinson's Disease, using a grape seed extract or one or more compounds derived therefrom. In particular, the present invention provides a method to treat a patient diagnosed with, or at the risk of developing, a neurodegenerative disease by administering a pharmaceutical composition comprising a grape seed extract or one or more compounds derived therefrom to the patient in a therapeutic amount to reduce the accumulation, aggregation or deposition of amyloid beta or its oligomers, and/or to reduce the misfolding, accumulation and/or aggregation of tau proteins or other proteins. | 05-12-2011 |
Mankit Ho, West Nyack, NY US
Patent application number | Description | Published |
---|---|---|
20080223116 | Drug Release Cell and a Method for Testing the Drug Release of a Suspension in a Liquid Utilizing the Same - A drug release cell useful in testing the drug release of a product in a liquid includes a first chamber and a second chamber with a membrane positioned in between such that the first chamber is located above the membrane and the second chamber is located below the membrane. The membrane has pores sized to permit a liquid and a released product, such as an insulin suspension, disposed in the second chamber to pass therethrough. When the drug release cell is filled with liquid and product is present in the second chamber the liquid is mixed with a mixing device to circulate the liquid and disperse released media throughout the liquid. Samples are taken at predetermined times from the first chamber through a sampling port to determine the concentration of the product in the liquid. The concentration data may then be utilized to create a drug release profile. Different formulations of a product may be tested in the drug release cell and the concentration data may be utilized to create distinguishable drug release profiles for each formulation. | 09-18-2008 |
20090064768 | Devices for Determining the Release Profile of Macromolecules and Methods of Using the Same - The present invention is directed to devices useful for determining the release profile of a macromolecule from a pharmaceutical composition comprising the macromolecule and methods of using the device. Transport of a macromolecule across a semi-permeable barrier is measured as a function of time using the device, the results of which can correlate with an in vivo release of the macromolecule from a pharmaceutical composition, a bioavailability of the macromolecule, or the stability or purity of the pharmaceutical composition comprising the macromolecule. | 03-12-2009 |
Patrick C. Ho, Hilton, NY US
Patent application number | Description | Published |
---|---|---|
20130265539 | EYEWEAR - Eyewear which is suitable for routine wear and within masks which are sealed against noxious environmental gases or penetration by water is provided by a frame made up of resilient metal parts including wires to provide the frame with a shape, which facilitates the placement of the eyewear on the head of the user while limiting the movement of the eyewear when in use so as to avoid breaking the seal of a mask inside of which the eyewear is disposed when the mask is donned by the user. The eyewear has a lens holding frame for holding lenses adjacent the eyes of the user's head and connected by a bridge across the user's nose. Flexible members bent arcuately around and in conformance with the sides of the head of the user have a kink whereby to facilitate acceptance between the sides of the head and the seal of the mask with sufficient tightness against the side of the head to limit movement of the frame and the space between the seal and the head thereby avoiding breaking of the seal when the mask is in operation. | 10-10-2013 |
20130276761 | VARIABLE-COMPRESSION ENGINE ASSEMBLY - Variable-compression engine assemblies with an internal combustion device and a flywheel are presented herein. An engine assembly is disclosed which includes an output shaft and a flywheel, which includes a variable cam surface and is slidably mounted onto the output shaft and rotatable about a flywheel axis. Also included is an internal combustion device with a piston that is movable along a central axis in a cycle between refracted and extended positions. The piston engages the variable cam surface, and the central axis of the piston is spaced from the flywheel axis. The cycle includes a power stroke when the piston moves from the retracted position to the extended position whereby the piston presses against the variable cam surface and thereby rotates the flywheel, and a compression stroke when the piston moves from the extended position to the retracted position responsive to the variable cam surface. | 10-24-2013 |
20140125939 | Eyeglass Frame With Temple Region For Interchangeable Ornaments - An eyeglass frame includes a pair of temple arms thereon, each temple arm having an ornament mounting area disposed along a temple region of the frame and a first end of the mounting area and a second end of the mounting area spaced apart from the first end; each temple arm having a diameter dimension of a size sufficient to fit through a hole opening of a detachable ornament, wherein each ornament mounting area is configured to detachably secure the ornament thereon. | 05-08-2014 |
20140363227 | Article, Interchangeable Component, And System - An article configured to secure an interchangeable component or components thereon, interchangeable components, and system for securing an interchangeable component or components to an article are disclosed. An embodiment of the system includes an article, locking unit, component support member, and interchangeable component. A tool-less attachment of the interchangeable component to the article enables the interchangeable component to be easily, quickly, and securely attached to an article, moved from one article to another, and replaced with another interchangeable component quickly. | 12-11-2014 |
20150185497 | Lens Carrier - Methods and apparatus for attaching lenses to a frame includes a lens carrier having one or more eyeglass lenses installed in one or more eye wires or rims that partially or completely encircle the lens. The lenses are joined by a nose bridge. The lens carrier includes a nose bridge spacer region and optionally a clamp that reversibly engages a brow bar or frame. | 07-02-2015 |
20150185500 | Displayed Image-Optimized Lens - A pair of prescription lenses adapted for use with a near-to-eye display, includes a first lens power region adjusted to a focal distance to focus an image displayed by the near-to-eye display and a second lens power region adjusted to a focal distance substantially the same as the focal distance of the first power region; eyeglasses containing the lens pair; and a method for optimizing the visual acuity of a wearer of prescription eyeglasses when observing an image generated by a near-to-eye display. | 07-02-2015 |
20160048038 | Prescription Lenses for Smart Eyewear - An eyeglass device configured for use with a smart eyewear near-to-eye display includes a pair of lenses having a prism which directs an eye's gaze of the wearer to a first power region to focus an image displayed by the near-to-eye display of the smart eyewear and a second power region to focus an image outside or beyond the near-to-eye display of the smart eyewear; and a method for optimizing the visual acuity of a wearer of smart eyewear when observing an image generated by a near-to-eye display and an image outside or beyond the near-to-eye displayed image. | 02-18-2016 |
Shih-Yin Ho, New York, NY US
Patent application number | Description | Published |
---|---|---|
20130060771 | METHOD AND SYSTEM FOR PRESENTING COMPOSITE RISK ASSESSMENT DATA AND CLINICAL TRIAL DATA FOR PHARMACEUTICAL DRUGS - A risk metrics information platform implemented as a reimbursement risk tracker application facilitates gathering, synthesizing, and presenting risk related data to users to foster a better understanding of pricing and reimbursement market risk for pipeline compounds and marketed pharmaceutical products. In one embodiment, the reimbursement risk tracker application provides a visually intuitive dashboard to help demonstrate how different global agencies look at a drug class or a therapeutic area. In another embodiment, a clinical trial tracker similarly facilitates gathering, synthesizing, and presenting of data relating to studies and outcomes across a number of different markets to foster a better understanding of the evaluation criteria as well as the conclusions of clinical trial studies. | 03-07-2013 |
Tracy Kwei-Liang Ho, Rego Park, NY US
Patent application number | Description | Published |
---|---|---|
20130340595 | Methods, Systems, and Media for Performing Visualized Quantitative Vibrato Analysis - Methods, systems, and media for performing visualized quantitative vibrato analysis are provided. In some embodiments, a method for analyzing musical vibrato in an audio file is provided, the method comprising: receiving, using a hardware processor, a target note from a user; receiving, using the hardware processor, a time-domain signal representing a piece of music comprising a plurality of notes, wherein the plurality of notes include the target note and the target note is played with a vibrato effect; converting, using the hardware processor, the time-domain signal to a frequency-domain signal; determining, using the hardware processor, a plurality of changes in frequency and intensity of the vibrato effect over time based on the frequency-domain signal; determining, using the hardware processor, a target frequency corresponding to the target note; and displaying, on a display, data about the changes in frequency and intensity of the vibrato effect over time and data about the target frequency. | 12-26-2013 |
Winson Ho, New York, NY US
Patent application number | Description | Published |
---|---|---|
20090099950 | Index Rebalancing - This invention relates to hedge fund indexing in general and methods and systems for constructing and maintaining investable hedge fund indices in particular. | 04-16-2009 |
Winson Ho, New York City, NY US
Patent application number | Description | Published |
---|---|---|
20090099949 | Reallocation - This invention relates to hedge fund indexing in general and methods and systems for constructing and maintaining investable hedge fund indices in particular. | 04-16-2009 |
20100063920 | Exposure Based on Capacity - This invention relates to hedge fund indexing in general and methods and systems for constructing and maintaining investable hedge fund indices in particular. | 03-11-2010 |