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Hitoshi Nobumasa

Hitoshi Nobumasa, Kanagawa JP

Patent application numberDescriptionPublished
20100029503ANALYSIS CHIP AND ANALYSIS METHOD - This invention is directed to an analysis chip comprising a substrate having a surface on which a selective binding substance is immobilized; a cover member adhered to the substrate; and particles movably contained or injected in a void between the substrate and the cover member; wherein the surfaces of the particles are coated with a surfactant. By this invention, generation of bubbles which inhibit the selective reaction between the test substance and the immobilized selective binding substance is suppressed, thereby reducing the deviation of data, suppressing the lowering of sensitivity, and promoting the reproducibility of the measurement.02-04-2010
20110098185COMPOSITION AND METHOD FOR DETERMINING OF ESOPHAGEAL CANCER - This invention relates to a composition, kit, or DNA chip for use in diagnosis of esophageal cancer, which comprises a plurality of polynucleotides selected from the group consisting of polynucleotides whose expression levels are varied in esophageal cancer tissues obtained from esophageal cancer patients when compared with cancer-free esophageal tissues obtained from esophageal cancer patients, mutants thereof, and fragments thereof, and to a method for detecting esophageal cancer using the composition, kit, or DNA chip.04-28-2011

Patent applications by Hitoshi Nobumasa, Kanagawa JP

Hitoshi Nobumasa, Kamakura JP

Patent application numberDescriptionPublished
20110015097SUPPORT CARRYING AN IMMOBILIZED SELECTIVE BINDING SUBSTANCE - A support carrying an immobilized selective binding substance, that the support surface has a polymer containing the structural unit represented by the following General Formula (1) in an amount of 10% or more with respect all monomer units, and a selective binding substance is immobilized on the support surface by binding to the carboxyl group formed thereon via a covalent bond:01-20-2011
20110028347SUPPORT CARRYING AN IMMOBILIZED SELECTIVE BINDING SUBSTANCE - A support carrying an immobilized selective binding substance, that the support surface has a polymer containing the structural unit represented by the following General Formula (1) in an amount of 10% or more with respect all monomer units, and a selective binding substance is immobilized on the support surface by binding to the carboxyl group formed thereon via a covalent bond:02-03-2011

Hitoshi Nobumasa, Shiga JP

Patent application numberDescriptionPublished
20090270267Composition and method for diagnosing esophageal cancer and metastasis of esophageal cancer - This invention relates to a composition, kit, or DNA chip comprising polynucleotides and antibodies as probes for detecting, determining, or predicting the presence or metastasis of esophageal cancer, and to a method for detecting, determining, or predicting the presence or metastasis of esophageal cancer using the same.10-29-2009
20100009347Kit and method for detecting urothelial cancer - This invention relates to a method for detecting in vitro a urothelial cancer, comprising measuring CXCL1 protein, or expression of a gene encoding the protein, in a biological sample from a subject, and to a kit for diagnosing a urothelial cancer comprising an antibody or nucleic acid probe, which is capable of binding specifically to the CXCL1 protein or a gene encoding the protein, respectively.01-14-2010
20100152055Composition and method for diagnosing kidney cancer and for predicting prognosis for kidney cancer patient - This invention relates to a composition, kit, DNA chip, and use thereof for detecting, diagnosing, and predicting metastasis of kidney cancer and/or for predicting the prognosis for kidney cancer, comprising one or a plurality of polynucleotides selected from the group consisting of polynucleotides, mutants thereof or fragments thereof, the expression levels of which vary in kidney cancer cells from a patient with a poor prognosis when compared with that in kidney cancer cells from a patient with a good prognosis; or antibodies or fragments thereof that bind specifically to polypeptides, mutants thereof or fragments thereof, the expression levels of which vary in the similar manner.06-17-2010

Patent applications by Hitoshi Nobumasa, Shiga JP

Hitoshi Nobumasa, Ohtsu-Shi JP

Patent application numberDescriptionPublished
20090297733SUBSTRATE FOR LAB-ON-A-CHIP - A lab-on-chip substrate includes a resin having a silicon content of 10% or less by weight as its base material and a hydrophilic polymer covalently bound onto the surface thereof by high-energy ray irradiation suitable for a protein-processing chip. The lab-on-chip substrate is resistant to washing and usable for an extended period of time without adsorption of proteins on the base material surface, i.e., a protein electrophoretic polymeric chip having a microchannel allowing high-accuracy analysis of trace amounts of proteins because of reduction in the amount of detection noise.12-03-2009

Hitoshi Nobumasa, Otsu-Shi JP

Patent application numberDescriptionPublished
20110201520COMPOSITION AND METHOD FOR DIAGNOSING ESOPHAGEAL CANCER AND METASTASIS OF ESOPHAGEAL CANCER - This invention relates to a composition, kit, or DNA chip comprising polynucleotides and antibodies as probes for detecting, determining, or predicting the presence or metastasis of esophageal cancer, and to a method for detecting, determining, or predicting the presence or metastasis of esophageal cancer using the same.08-18-2011