Hirsch, US
Andrea Hirsch, New York, NY US
Patent application number | Description | Published |
---|---|---|
20140244442 | METHOD FOR AUTOMATICALLY FILLING A VIRTUAL SHOPPING CART WITH ITEMS - A method of automatically filling a Virtual shopping cart with items. Users automatically fill their Virtual shopping carts with a Predetermined List of Items that are required or recommended to create or complete a Product(s). The Method allows Users to automatically fill their Virtual or online shopping cart(s) with selected items in one easy step. Users can customize a List of Items and then automatically fill their Virtual shopping carts with the customized List of Items in one step. The Invention comprises of the Method of automatically filling a Virtual shopping cart in one step with a Predetermined List of Items, which may be complete or customized, for purchase, comprising of the following steps: Displaying a Predetermined List of Items and information about the items; Allowing a User to customize the group of items; Adding the complete or customized group of items to a Virtual shopping cart in one step. | 08-28-2014 |
Bernard S. Hirsch, Dallas, TX US
Patent application number | Description | Published |
---|---|---|
20140267582 | PRIVACY SETTING FOR MEDICAL COMMUNICATIONS SYSTEMS - A communication arrangement including a room having at least one communication device therein, the at least one communication device receiving in-room images, in-room video and/or in-room audio within the room. The communication arrangement also includes a communication system for transmitting the in-room images, in-room video and/or in-room audio from within the room to a location remote from the room. The communication system has a privacy setting that, when activated, prevents viewing of the in-room images or in-room video and/or hearing of the in-room audio from within the room at the location remote from the room and communicates to the location remote from the room that the privacy setting is activated. | 09-18-2014 |
Brooke Elizabeth Bishop Hirsch, Broomfield, CO US
Patent application number | Description | Published |
---|---|---|
20120009212 | CONJUGATES UTILIZING PLATFORM TECHNOLOGY FOR STIMULATING IMMUNE RESPONSE - Templated conjugates created from naturally-occurring protein sequences found in pathogens, such as viruses, are disclosed. The sequences are “templated” into a consensus coiled-coil sequence in order to form a two-stranded antigen suitable for immunization of a subject. | 01-12-2012 |
20120014972 | INFLUENZA VIRUS COMPOSITIONS AND METHODS FOR UNIVERSAL VACCINES - The disclosure relates at least in part to embodiments of compositions and methods including vaccines for protection against multiple serologically distinct strains of influenza virus. This disclosure provides significant advances and addresses important needs in the influenza vaccine field. | 01-19-2012 |
20140154282 | CONJUGATES UTILIZING PLATFORM TECHNOLOGY FOR STIMULATING IMMUNE RESPONSE - Templated conjugates created from naturally-occurring protein sequences found in pathogens, such as viruses, are disclosed. The sequences are “templated” into a consensus coiled-coil sequence in a platform in order to form a two-stranded antigen suitable for immunization of a subject. | 06-05-2014 |
Bruce Hirsch, Port Washington, NY US
Patent application number | Description | Published |
---|---|---|
20090014232 | Multi-layered, peelable hygienic cover for a stethoscope - A disposable stethoscope cover that covers at least the surface of the diaphragm is disclosed. The cover contacts a patient during use and reduces transmittal of microorganisms. The cover is in the form of a flexible sheet having a top and a bottom surface. The sheet has an adhesive material on a portion of the surface thereof that secures the sheet to the surface of the diaphragm. The sheet further includes at least one wing extending from the sheet. The wing has an adhesive on at least one surface thereof for securing the wing to the sheet when the wing is folded over at least a portion of a tube section of the stethoscope. | 01-15-2009 |
Candice Nicole Hirsch, Saint Paul, MN US
Patent application number | Description | Published |
---|---|---|
20140283214 | MAIZE SUGARY ENHANCER SEQUENCES - The sugary enhancer phenotype in maize results from the absence of expression of a nucleotide sequence located on Chromosome 2. Methods for screening, selecting or identifying plants containing the sequence and for estimating the sucrose content in maize plants are disclosed. Genetically modified plants having altered expression of the nucleotide sequence are provided. | 09-18-2014 |
Daniel S. Hirsch, Savage, MN US
Patent application number | Description | Published |
---|---|---|
20120062917 | MASS CUSTOMIZATION OF ARTICLES HAVING DIMENSIONAL AND/OR ANIMATED IMAGES - Mass customization of articles with a customized composite or dimensional image created from one or more custom images, such as photographs, text, and the like. The customized composite image is automatically generated by interlacing, or otherwise combining, the one or more custom or personalized images, and is automatically placed or imposed in a digital template to form a print ready file. The print file is then digitally printed on a substrate and a lens is married thereto such that the composite image is viewable through the lens. Alternatively, the print ready file, or at least the customized composite image, is printed directly on the back of a lens such that the composite image is viewable through the lens. | 03-15-2012 |
David Hirsch, Tampa, FL US
Patent application number | Description | Published |
---|---|---|
20120246045 | SYSTEM AND METHOD FOR USING AN ANALOGY IN THE MANAGEMENT OF PERSONAL FINANCES - A system for presenting a user's financial status captures a user's financial, demographic and goal information and calculates the user's financial status based upon their goals. The system then translates the user's financial status into an analogy that the user is apt to understand better than financial terms. The user is presented with their financial status in terms of the analogy such as a score. One such analogy is a football game, in which the user's financial status is translated and portrayed/displayed in terms of a football game, winning (attaining his or her goals) or losing (not doing well at attaining the goals), etc. | 09-27-2012 |
20120246046 | SYSTEM AND METHOD FOR USING AN ANALOGY IN THE MANAGEMENT OF ASSETS - A system for categorizing and presenting a user's assets captures a user's asset data, demographic and risk information and maps the user's asset data to a formation of an analogy such as a football analogy. The system then presents the asset data in a graphical representation of the analogy in a format that the user is apt to understand better than raw financial terms. One such analogy is a football game, in which the user's asset data is translated and portrayed/displayed in terms of players in positions within a football formation. | 09-27-2012 |
Denise Hirsch US
Patent application number | Description | Published |
---|---|---|
20110311563 | Synthetic Antigenic Peptides and Lipopeptides Derived from Mycobacterium Avium Subsp. Paratubuerculosis - The current invention relates to the diagnosis and treatment of diseases resulting from infections by | 12-22-2011 |
Dick Hirsch, Phoenix, AZ US
Patent application number | Description | Published |
---|---|---|
20100090816 | Computer Screen Blanking Systems - A system for detecting vehicular motion to blank a computer screen. The system includes filtering the motion to determine whenever the motion is consistent with vehicular motion. The system includes communicating the vehicular motion to a computer. The system includes blanking the screen of the computer whenever detecting vehicular motion and blanking the screen of the computer whenever the motion detector is not attached the portable computer. | 04-15-2010 |
Donald Ivan Hirsch, Cottage Grove, MN US
Patent application number | Description | Published |
---|---|---|
20080311403 | LAMINATION APPARATUS AND METHODS - Components for the manufacture of polymer electrolyte membrane fuel cells are provided, as well as apparatus and automatable methods for their manufacture by rotary die cutting and by lamination of various layers to form membrane electrode assemblies. A method and apparatus for performing the method are provided comprising die-cutting webs of catalyst decal materials or electrode materials to make first and second workpieces at first and second rotary die stations; holding the die-cut workpieces by action of sub-ambient air pressure to an endless perforated belt of first and second vacuum conveyors, typically before they are fully cut from the first and second webs; transporting first and second workpieces to opposing sides of a membrane in a laminating station; concurrently feeding the first and second workpieces into the laminating nip adjacent to the membrane, and laminating the first and second workpieces to the membrane. | 12-18-2008 |
20130008595 | LAMINATION APPARATUS AND METHODS - Components for the manufacture of polymer electrolyte membrane fuel cells are provided, as well as apparatus and automatable methods for their manufacture by rotary die cutting and by lamination of various layers to form membrane electrode assemblies. A method and apparatus for performing the method are provided comprising die-cutting webs of catalyst decal materials or electrode materials to make first and second workpieces at first and second rotary die stations; holding the die-cut workpieces by action of sub-ambient air pressure to an endless perforated belt of first and second vacuum conveyors, typically before they are fully cut from the first and second webs; transporting first and second workpieces to opposing sides of a membrane in a laminating station; concurrently feeding the first and second workpieces into the laminating nip adjacent to the membrane, and laminating the first and second workpieces to the membrane. | 01-10-2013 |
Fred R. Hirsch, Denver, CO US
Patent application number | Description | Published |
---|---|---|
20100196366 | Gefitnib Sensitivity-Related Gene Expression and Products and Methods Related Thereto - Disclosed is the identification, provision and use of a panel of biomarkers that predict sensitivity or resistance to EGFR inhibitors, and products and processes related thereto. In one embodiment, a method is described for selecting a cancer patient who is predicted to benefit from therapeutic administration of an EGFR inhibitor, an agonist thereof, or a drug having substantially similar biological activity as EGFR inhibitor. Also described is a method to identify molecules that interact with the EGFR pathway to allow or enhance responsiveness to EGFR inhibitors, as well as a plurality of polynucleotides or antibodies for detection of the expression of genes that are indicative of sensitivity or resistance to EGFR inhibitors, an agonist thereof, or a drug having substantially similar biological activity as EGFR inhibitors. A method to identify a compound with the potential to enhance the efficacy of EGFR inhibitors is also described. | 08-05-2010 |
20110262453 | Markers for Assessing the Susceptibility of Cancer to IGF-1R Treatment - The present invention relates to a method of predicting response of a cancer cell tissue to IGF-IR treatment. The inventors have observed a direct relationship between the expression of survivin, ErbB | 10-27-2011 |
20120177641 | Gefitnib Sensitivity-Related Gene Expression and Products and Methods Related Thereto - Disclosed is the identification, provision and use of a panel of biomarkers that predict sensitivity or resistance to EGFR inhibitors, and products and processes related thereto. In one embodiment, a method is described for selecting a cancer patient who is predicted to benefit from therapeutic administration of an EGFR inhibitor, an agonist thereof, or a drug having substantially similar biological activity as EGFR inhibitor. Also described is a method to identify molecules that interact with the EGFR pathway to allow or enhance responsiveness to EGFR inhibitors, as well as a plurality of polynucleotides or antibodies for detection of the expression of genes that are indicative of sensitivity or resistance to EGFR inhibitors, an agonist thereof, or a drug having substantially similar biological activity as EGFR inhibitors. A method to identify a compound with the potential to enhance the efficacy of EGFR inhibitors is also described. | 07-12-2012 |
20130004970 | METHODS FOR PREDICTION OF CLINICAL OUTCOME TO EPIDERMAL GROWTH FACTOR RECEPTOR INHIBITORS BY CANCER PATIENTS - Disclosed are biomarkers, methods and assay kits for the identification of cancer patients who are predicted to benefit, or not to benefit, from the therapeutic administration of an epidermal growth factor receptor (EGFR) inhibitor. The biomarkers of the present invention include detection of EGFR and HER 2 gene amplification and polysomy, EGFR protein expression, EGFR mutations, phosphorylated Akt protein expression, and various combinations of such biomarkers, as well as the combination of these biomarkers with mutations in the tyrosine kinase domain of the EGFR gene. Increased EGFR gene copy number, increased HER2 gene copy number, increased EGFR protein expression, activated AKT protein expression (phosphorylated AKT) and EGFR mutations are all associated with better outcome for cancer patients treated with EGFR inhibitors. The invention provides a diagnostic paradigm based on each of these tests and combinations of these tests to select cancer patients who will benefit from EGFR inhibitor therapy, as well as a diagnostic paradigm to select cancer patients who will not benefit from EGFR inhibitor therapy. | 01-03-2013 |
Gary Hirsch, Wilton, CT US
Patent application number | Description | Published |
---|---|---|
20130178959 | Method and System for Predicting and Measuring Event Durations and Operating Related Contests - The present invention allows event participants to predict the duration of an event before it begins, monitor the event duration, establish and record the official event duration and compare the official event duration to the participants' predictions. In the preferred embodiment of the invention, users employ a computer or mobile device interface to predict, monitor and establish the duration of a business meeting or conference call and compete to earn rewards based on the accuracy of their respective predictions and from other meeting participants. | 07-11-2013 |
Gerald Philip Hirsch, Clarksville, TN US
Patent application number | Description | Published |
---|---|---|
20100288322 | Solar to electric system - Conversion of solar heat into electrical energy is achieved using a parabolic reflector, a heat transfer medium, a high-density heat store and a thermoelectric generator. The system is useful for various forms of stationary and moving applications. Using stored heat derived from sunlight provides day and night electrical supply over many days depending on the size of the solar collector and heat store. Moving applications are achieved using a mobile heat store with attached thermoelectric generator. | 11-18-2010 |
20130154375 | Solar Home Electrification With Grid Connection - A means of providing solar powered electricity for day and nighttime use supported in part by power from the grid to allow a small generator to electrify the home or business with a small generator operating with much larger capacity. Excess solar energy is provided to the power company as needed. | 06-20-2013 |
20140076826 | THERMOELECTRIC DEVICE WITH MAKE-BEFORE-BREAK HIGH FREQUENCY CONVERTER - An improved circular multi-element semiconductor thermoelectric hybrid utilizes a make-before-break high frequency switching output component to provide nominal alternating current voltage outputs. Overall efficiency of heat conversion is improved by coupling a chiller to the thermoelectric generator where exhaust heat produces chilled liquid or air that is conveyed to the cold side of the thermoelectric device. The thermoelectric generator is used in a variety of transportation vehicles including manufactured vehicles, retrofitted vehicles and vehicle power combinations. | 03-20-2014 |
20140196274 | THERMOELECTRIC EVALUATION AND MANUFACTURING METHODS - A means for determining the electrical resistance and resistivity of thermoelectric material allows quality control at all steps in the construction of a bismuth telluride and antimony telluride thermoelectric generator. The method involves measuring negative thermoelectric voltage with no current flowing and then a measure of negative thermoelectric voltage while forcing known current through the material in the same direction as shorted to accurately determine thermoelectric resistance. A manual and automatic method of manufacturing thermoelectric rings using forcing current for in-process testing means. | 07-17-2014 |
20140208773 | THERMOELECTRIC DEVICE WITH MAKE-BEFORE-BREAK HIGH FREQUENCY CONVERTER - An improved circular multi-element semiconductor thermoelectric hybrid utilizes a make-before-break high frequency switching output component to provide nominal alternating current voltage outputs. Overall efficiency of heat conversion is improved by coupling a chiller to the thermoelectric generator where exhaust heat produces chilled liquid or air that is conveyed to the cold side of the thermoelectric device. The thermoelectric generator is used in a variety of transportation vehicles including manufactured vehicles, retrofitted vehicles and vehicle power combinations. | 07-31-2014 |
Gerald Philip Hirsch US
Patent application number | Description | Published |
---|---|---|
20100288323 | Thermoelectric evaluation and manufacturing methods - A means for determining the electrical resistance and resistivity of thermoelectric material allows quality control at all steps in the construction of a bismuth telluride and antimony telluride thermoelectric generator. The method involves measuring negative thermoelectric voltage with no current flowing and then a measure of negative thermoelectric voltage while forcing known current through the material in the same direction as shorted to accurately determine thermoelectric resistance. A manual and automatic method of manufacturing thermoelectric rings using forcing current for in-process testing means. | 11-18-2010 |
20100288326 | Solar home electrification with grid connection - A means of providing solar powered electricity for day and nighttime use supported in part by power from the grid to allow a small generator to electrify the home or business with a small generator operating with much larger capacity. Excess solar energy is provided to the power company as needed. | 11-18-2010 |
Gerald Phillip Hirsch, Clarksville, TN US
Patent application number | Description | Published |
---|---|---|
20120247847 | THERMOELECTRIC DEVICE WITH MAKE-BEFORE-BREAK HIGH FREQUENCY CONVERTER - An improved circular multi-element semiconductor thermoelectric hybrid utilizes a make-before-break high frequency switching output component to provide nominal alternating current voltage outputs. Overall efficiency of heat conversion is improved by coupling a chiller to the thermoelectric generator where exhaust heat produces chilled liquid or air that is conveyed to the cold side of the thermoelectric device. The thermoelectric generator is used in a variety of transportation vehicles including manufactured vehicles, retrofitted vehicles and vehicle power combinations. | 10-04-2012 |
20140163714 | THERMOELECTRIC EVALUATION AND MANUFACTURING METHODS - A means for determining the electrical resistance and resistivity of thermoelectric material allows quality control at all steps in the construction of a bismuth telluride and antimony telluride thermoelectric generator. The method involves measuring negative thermoelectric voltage with no current flowing and then a measure of negative thermoelectric voltage while forcing known current through the material in the same direction as shorted to accurately determine thermoelectric resistance. A manual and automatic method of manufacturing thermoelectric rings using forcing current for in-process testing means. | 06-12-2014 |
Gerald Phillip Hirsch US
Patent application number | Description | Published |
---|---|---|
20120090534 | Solid state thermoelectric power converter - High efficiency conversion of heat energy to electrical energy is achieved using a ring of metallic components and anodically sliced, reduced barriers, high purity n-type and p-type semiconductor wafers. Energy produced by heating one set of fins and cooling another set is extracted from a ring of bismuth telluride based n-type wafers and antimony telluride based p-type wafers using make-before-break control of MOSfet switch banks. Standard AC frequencies and DC output result from rectification of make-before-break high frequency switched very high currents in the ring and a DC to AC converter. Solar energy stored in porcelain fragments extends the time that solar energy can be used as the heat source for the thermoelectric generator device. | 04-19-2012 |
Heather Hirsch, Boston, MA US
Patent application number | Description | Published |
---|---|---|
20120220664 | USE OF METFORMIN IN CANCER TREATMENT AND PREVENTION - Disclosed herein is a method for treating a tumor in a subject in need thereof comprising administering an enhancing amount of metformin and a reduced amount of one or more chemotherapeutic agents. One example of an enhancing amount of metformin is about 250 mg/day. Also disclosed is a Untreated method for preventing cancer or delaying the recurrence of cancer in a subject comprising administering an effective amount of metformin to the subject. In one example of such a method, the amount of metformin is about 75 mg/day. Also disclosed is a composition comprising an enhancing amount of metformin, and a reduced amount of one or more chemotherapeutic agents and a pharmaceutically acceptable carrier. Kits comprising metformin and one or more chemotherapeutic agents are also disclosed. | 08-30-2012 |
Heather A. Hirsch, Brookline, MA US
Patent application number | Description | Published |
---|---|---|
20150051227 | PREDICTIVE BIOMARKER USEFUL FOR CANCER THERAPY MEDIATED BY A CDK INHIBITOR - The present invention provides a predictive biomarker whose expression level is useful for identifying patients responsive to a therapeutically effective dose of a CDK inhibitor. In one embodiment of the invention, the predictive biomarker is the ratio of MCL-1 to BCL-xL (MCL-1:BCL-xL ratio) and the CDK inhibitor is SCH 927965 (Dinaciclib). | 02-19-2015 |
Herman Hirsch, New York, NY US
Patent application number | Description | Published |
---|---|---|
20090055302 | System and method for integrating a convertible security with a call spread - The present invention relates to a method and system for providing a financial instrument by integrating a convertible security with a call spread to form a financial instrument having the benefits of low coupons and tax efficiencies. The call spread includes a first call option that mirrors features of the convertible security and a second call option that has a higher strike price than that of the first call option. | 02-26-2009 |
20090063327 | System and method for integrating a convertible security with a call spread - The present invention relates to a method and system for providing a financial instrument by integrating a convertible security with a call spread to form a financial instrument having the benefits of low coupons and tax efficiencies. The call spread includes a first call option that mirrors features of the convertible security and a second call option that has a higher strike price than that of the first call option. | 03-05-2009 |
James Hirsch, Springfield, OR US
Patent application number | Description | Published |
---|---|---|
20130090470 | OPTICALLY-DETECTABLE ENZYME SUBSTRATES AND THEIR METHOD OF USE - The present invention relates to compounds that are substrates for an enzyme, and upon reaction with the enzyme provide a detectable response, such as an optically detectable response. In particular, the compounds have utility in detecting the presence of a β-lactamase in a sample. In addition to the compounds, methods are disclosed for analyzing a sample for the presence of a β-lactmase, for example, as an indicator of expression of a nucleic acid sequence including a sequence coding for a β-lactmase. Kits are disclosed that include the disclosed compounds and additional components, for example, cells, antibodies, a β-lactmase or instructions for using the components in an assay. | 04-11-2013 |
James David Hirsch, Springfield, OR US
Patent application number | Description | Published |
---|---|---|
20090047692 | OPTICALLY-DETECTABLE ENZYME SUBSTRATES AND THEIR METHOD OF USE - The present invention relates to compounds that are substrates for an enzyme, and upon reaction with the enzyme provide a detectable response, such as an optically detectable response. In particular, the compounds have utility in detecting the presence of a β-lactamase in a sample. In addition to the compounds, methods are disclosed for analyzing a sample for the presence of a β-lactmase, for example, as an indicator of expression of a nucleic acid sequence including a sequence coding for a β-lactmase. Kits are disclosed that include the disclosed compounds and additional components, for example, cells, antibodies, a β-lactmase or instructions for using the components in an assay. | 02-19-2009 |
20120040380 | OPTICALLY-DETECTABLE ENZYME SUBSTRATES AND THEIR METHOD OF USE - The present invention relates to compounds that are substrates for an enzyme, and upon reaction with the enzyme provide a detectable response, such as an optically detectable response. In particular, the compounds have utility in detecting the presence of a β-lactamase in a sample. In addition to the compounds, methods are disclosed for analyzing a sample for the presence of a β-lactmase, for example, as an indicator of expression of a nucleic acid sequence including a sequence coding for a β-lactmase. Kits are disclosed that include the disclosed compounds and additional components, for example, cells, antibodies, a β-lactmase or instructions for using the components in an assay. | 02-16-2012 |
Joachim Hirsch, Colleyville, TX US
Patent application number | Description | Published |
---|---|---|
20100140363 | Air powered terminal unit and system - An air powered terminal unit comprising a housing, a fluid to air heat exchanger, an induced flow air inlet upstream of the heat exchanger, a venturi downstream of the heat exchanger, a nozzle cooperatively disposed with the venturi so as to direct a primary air jet discharged from the nozzle through the venturi, such that an air flow through the heat exchanger is induced, and an outlet downstream of the venturi for discharging a mixture of the induced flow air and the primary air. | 06-10-2010 |
20120088445 | Air distribution unit - An air distribution unit comprising a housing having a receiving chamber, said receiving chamber is in communication externally and internally of said housing, a first air exhaust duct in said housing in communication with said receiving chamber and with said exterior for exhausting air from said receiving chamber to a lower portion of the housing, a second air exhaust duct in said housing in communication with said receiving chamber and with said exterior for exhausting air from said receiving chamber to an upper portion of the housing, an air supply duct in said housing having a first end in communication with said receiving chamber and a second end in communication with said first air exhaust duct, and a damper communicating with said receiving chamber for selectively routing air from said receiving chamber to either the first air exhaust duct or said second air exhaust duct. | 04-12-2012 |
20140231045 | INDUCTION DISPLACEMENT UNIT - An induction displacement unit comprising an induction plenum comprising a plurality of first nozzles communicating with a first discharge plenum and a plurality of second nozzles communicating with a second discharge plenum, a return air plenum, a heating coil disposed between the return air plenum and the first discharge plenum, a cooling coil disposed between the return air plenum and the second discharge plenum, the induction plenum vertically disposed between the heating coil and the cooling coil, the heating coil disposed in an upper portion of the unit, the first discharge plenum disposed to induce a substantially vertical discharge, and the second discharge plenum disposed to induce a substantially horizontal discharge. | 08-21-2014 |
20140231046 | INDUCTION DISPLACEMENT UNIT - An induction displacement unit comprising an induction plenum comprising a plurality of first nozzles communicating with a first discharge plenum and a plurality of second nozzles communicating with a second discharge plenum, a return air plenum, a heating coil disposed between the return air plenum and the first discharge plenum, a cooling coil disposed between the return air plenum and the second discharge plenum, the induction plenum vertically disposed between the heating coil and the cooling coil, the heating coil disposed in an upper portion of the unit, the first discharge plenum disposed to induce a substantially vertical discharge, and the second discharge plenum disposed to induce a substantially horizontal discharge. | 08-21-2014 |
Joshua Hirsch, Brecksville, OH US
Patent application number | Description | Published |
---|---|---|
20140163426 | PERFORMANCE TEST FOR EVALUATION OF NEUROLOGICAL FUNCTION - This disclosure relates to a system and method to implement a performance test to help evaluate a patient's neurological and cognitive function. The performance test can be executed by the patient autonomously using a portable computing device, such as a tablet computer or smart phone. The portable computing device can be programmed to execute a set of modules configured to assess motor and cognitive performance, such as a manual function test module, a cognitive processing speed test module, and a movement assessment test module. The set of modules can also include a collection module to aggregate test data from the manual function test module, the cognitive processing speed test module, and the movement assessment test module. | 06-12-2014 |
Joy Hirsch, New York, NY US
Patent application number | Description | Published |
---|---|---|
20110301495 | IMAGES OF LANGUAGE-SENSITIVE NEUROCIRCUITRY AS A DIAGNOSTIC FOR AUTISM - The disclosed subject matter provides on ore more imaging techniques during passive auditory stimulation to objectively provide a diagnostic indicator of ASD. These techniques include functional MRI (fMRI), diffusion tensor imaging (DTI) and tractography, and combinations thereof. In one embodiment, a method is disclosed that uniquely provides an objective (imaging) physiological technique to diagnose early autism and to monitor progress following therapeutic intervention. | 12-08-2011 |
20120143041 | Images Of Language-Sensitive Neurocircuitry As A Diagnostic For Autism - The disclosed subject matter provides on ore more imaging techniques during passive auditory stimulation to objectively provide a diagnostic indicator of ASD. These techniques include functional MRI (fMRI), diffusion tensor imaging (DTI) and tractography, and combinations thereof. In one embodiment, a method is disclosed that uniquely provides an objective (imaging) physiological technique to diagnose early autism and to monitor progress following therapeutic intervention. | 06-07-2012 |
Julie Beth Hirsch, Branchburg, NJ US
Patent application number | Description | Published |
---|---|---|
20120225053 | COMPOSITIONS AND METHODS FOR THE PREVENTION AND TREATMENT OF CONDITIONS ASSOCIATED WITH INFLAMATION - The present invention provides methods for preventing, treating, managing and/or ameliorating a condition associated with inflammation (e.g., an inflammatory disorder) or a symptom thereof, the methods comprising administering to a subject in need thereof an effective amount of a theaflavin composition and an effective amount of one or more therapies other than such a theaflavin composition. In particular, the present invention provides methods for preventing, treating, managing and/or ameliorating a condition associated with inflammation (e.g., an inflammatory disorder) or a symptom thereof, the methods comprising administering to a subject in need thereof an effective amount of a theaflavin composition, an effective amount of a glucosamine composition, and optionally one or more other therapies. | 09-06-2012 |
Karl F. Hirsch, Sammamish, WA US
Patent application number | Description | Published |
---|---|---|
20110125608 | OPEN, NEUTRAL ELECTRONIC DISTRIBUTION SYSTEM FOR DIGITAL CONTENT PROVIDING DISTRIBUTION CHANNEL SUPPORT TO PUBLISHERS AND RETAILERS AND ABSTRACT FULFILLMENT FOR PUBLISHERS - An online service and system are provided through which digital content publishers can package, protect, market and sell their content through on-line retailers, and through which on-line retailers can both build a unique inventory of digital content with all associated marketing metadata to sell through their on-line stores and seamlessly integrate the digital content into their on-line shopping cart. The system provides publishers with abstract fulfillment such that they only have to upload the content for that product one time to a server or other device configured as an open, neutral electronic distribution platform that can provide third party verification to the publisher of a transaction between the retailer and the consumer for that publisher's product. Content selected from the server by different retailers is dynamically rebranded using the retailer-specific information corresponding to those respective retailers. | 05-26-2011 |
Keith Hirsch, Canton, MI US
Patent application number | Description | Published |
---|---|---|
20130137622 | COMPOSITION FOR DISSOLVING AND/OR INHIBITING DEPOSITION OF SCALE ON A SURFACE OF A SYSTEM - A composition for dissolving and/or inhibiting deposition of scale on a surface of a system comprises an acidic component, a wetting agent, and a corrosion inhibitor. The composition may further comprise water. The acidic component comprises an alkanesulfonic acid, e.g. methanesulfonic acid (MSA). The wetting agent comprises a surfactant. The corrosion inhibitor comprises an amphoteric surfactant. The alkanesulfonic acid is present in an amount of at least about 50 weight percent (wt %), the surfactant is present in an amount of from about 0.1 to about 30 wt %, and the amphoteric surfactant is present in an amount of from about 0.025 to about 20 wt %, each based on 100 wt % of the alkanesulfonic acid, the surfactant, and the amphoteric surfactant combined. A method of dissolving and/or inhibiting deposition of scale on the surface of the system comprises the step of contacting the surface of the system with the composition. | 05-30-2013 |
20140312264 | Colloidal Sol And Method Of Making Same - A colloidal sol and a method of making colloidal sol that is capable of controlling the resulting particle size and more specifically, using a potassium hydroxide process to obtain a colloidal sol having a single peak of average particle sizes. | 10-23-2014 |
Keith A. Hirsch, Canton, MI US
Patent application number | Description | Published |
---|---|---|
20110049052 | METHOD FOR INHIBITING THE DEPOSITION OF SILICA AND/OR SILICATE COMPOUNDS IN AQUEOUS SYSTEMS - A method inhibits the deposition of silica and/or silicate compounds on a surface in an aqueous system. The method includes the step of adding a polymer to the aqueous system. The polymer comprises the reaction product of a natural oil component and an alkylene oxide. The polymer of the subject invention has a core, comprising a fatty acid or an ester thereof, and a plurality of polymeric side chains bonded to the core. The plurality of polymeric side chains comprise alkyleneoxy groups selected from the group of ethyleneoxy groups, propyleneoxy groups, butyleneoxy groups, and combinations thereof. | 03-03-2011 |
20110049053 | METHOD FOR INHIBITING THE DEPOSITION OF SILICA AND/OR SILICATE COMPOUNDS IN AQUEOUS SYSTEMS - A method of inhibiting the deposition of silica and/or silicate compounds on a surface in an aqueous system is provided. The method comprises the step of adding a polymer to the aqueous system. The polymer comprises at least one constitutional unit (i) and at least one additional constitutional unit (ii). The constitutional unit (i) is represented by the formula: | 03-03-2011 |
20130017241 | Encapsulated Chlorine Dioxide Generator - An encapsulated chlorine dioxide generator is provided. The encapsulated generator includes a core particle that includes a metal chlorite and a solid acid. The encapsulated generator also includes a protective layer that is disposed about at least a portion of the core particle. The protective layer includes a copolymer of polyvinyl alcohol and a polyalkylene glycol. The encapsulated generator is formed in a method including the steps of forming the core particle and disposing the protective layer about the core particle. The encapsulated generator is also used in a method of cleaning an environment. The method of cleaning the environment includes the steps of providing the encapsulated generator and forming chlorine dioxide from the encapsulated chlorine dioxide generator to clean the environment. | 01-17-2013 |
Kenneth A. Hirsch, Scottsdale, AZ US
Patent application number | Description | Published |
---|---|---|
20140100773 | Method of Assistance for the Visually Impaired - A method of providing assistance for the blind or otherwise visually impaired is provided. A user utilizes a mobile device to communicate with a remote operator in the event that the user is in need of assistance in orienting themselves with their surroundings or locating and viewing objects. The mobile device connects to a remote server through a data connection, providing audio, video, and other data communication with an operator. | 04-10-2014 |
20140135035 | System for Item and Location Information Distribution - A system for item and location information distribution utilizes a mobile device, at least one wireless information node, and a data server. The information node actively broadcasts a node identification (NID) via a wireless communication signal. When a user brings the mobile device within range of the wireless communication signal, the signal is received by the mobile device, allowing it to receive the NID. The mobile device then requests data related to the node from either the data server or a locally stored database generated from data previously retrieved from the data server. Software on the mobile device may then display headings and subheadings on the screen of the mobile device. The user may select a particular heading or subheading to display the content of the associated chapter or subchapter on the screen of the mobile device. | 05-15-2014 |
Lindsey M. Hirsch, Golden Valley, MN US
Patent application number | Description | Published |
---|---|---|
20140308692 | METHOD FOR DETERMINATION OF DIETARY FIBER CONTENT BY CENTRIFUGATION - The amount of dietary fiber in a sample can be quantified by dissoluting the sample to produce a dietary fiber solution and then centrifuging the dietary fiber solution to produce a pellet and a supernatant liquid. After separating the supernatant liquid from the pellet, the pellet can be analyzed to determine a content of non-dietary fiber components in the pellet. The dietary fiber content in the pellet can be determined from the content of the non-dietary fiber components in the pellet. By using centrifugation to help isolate the dietary fiber in the sample, fiber loss may be minimized, leading to a more accurate determination of the content of dietary fiber in the sample. | 10-16-2014 |
Marc Hirsch, Roanoke, VA US
Patent application number | Description | Published |
---|---|---|
20140151596 | THERMALLY CONDUCTIVE, CORROSION RESISTANT COATINGS - A thermally conductive, corrosion resistant coating composition for use as a substrate coating. The thermally conductive, corrosion resistant coating composition comprising a waterborne polyurethane polymer, and at least one additive. Other thermally conductive, corrosion resistant coating compositions also comprise thermally conductive particles. | 06-05-2014 |
Mark Hirsch, New York, NY US
Patent application number | Description | Published |
---|---|---|
20130297468 | SYSTEMS AND METHODS FOR TRACKING TIME - Systems and methods of the present disclosure facilitate tracking time. In some embodiments, the method obtains first time information. The first time information can be obtained via a timer embedded in an application executing on a first device. The method may associate the first time information with a first task identifier and generate a timesheet based on the associated first time information, which may include a unique indication of the first task identifier. The method may display the generated timesheet on a display of a mobile device. The method may modify the generated timesheet to include a second time information, which may correspond to a second task identifier. The timesheet can be modified via the mobile device touch interface. The method may display the modified timesheet with a unique indication of the second task identifier. The method may submit, via the mobile device, the timesheet to a time tracker server. | 11-07-2013 |
Mark A. Hirsch, Vicksburg, MI US
Patent application number | Description | Published |
---|---|---|
20080236322 | Transmission range shift control with neutral position lock - A range selection control system for a transmission facilitates safe operation of a power take off. A fluid actuated range piston assembly within a range cylinder moves between low range and high range positions. Range cylinder and range piston assembly define sealed high range and low range chambers. A neutral cylinder intersects range cylinder. A fluid actuated neutral piston assembly within neutral cylinder defines a neutral chamber. Neutral piston assembly engages range control piston assembly responsive to pressurization of neutral chamber. Neutral piston assembly is received by an engagement feature of range piston assembly when range control piston assembly is in a neutral position, retaining range piston assembly there. An electrically responsive locking mechanism locks neutral piston assembly in place when range piston assembly is in the neutral position. The locking is controlled by a condition of an electrical switch indicating a transmission condition. | 10-02-2008 |
20130075224 | TRANSMISSION OVERDRIVE YOKE POSITION SENSOR FOR RANGE TRIGGER - Disclosed is an exemplary transmission clutch fork position sensor including an elongated bar and a clutch fork slidably engaging the elongated bar. A yoke bar includes a first end coupled to the clutch fork for concurrent movement therewith. A position sensor operably engages the yoke bar, and is operable for detecting a position of the yoke bar. | 03-28-2013 |
Mark J. Hirsch, Fairport, NY US
Patent application number | Description | Published |
---|---|---|
20090257787 | HSD WIRES USING FIBROUS CARBON NANOMATERIAL YARNS - A Hybrid Scavengeless Development electrophotographic printing system is provided wherein the electrode wires contain carbon nanotube yarn. The use of carbon nanotube yarn alleviates the problem of fundamental strobing image defects, because the electrodes made from the carbon nanotube yarn can be put at a higher tension to density set point, and thereby achieve fundamental resonance frequencies larger than that obtainable from steel. Additionally the yarn's strength is sufficient to withstand the typical forces it is subjected to in a Hybrid Scavengeless Development environment. | 10-15-2009 |
20140127624 | DISPENSING TONER ADDITIVES VIA CARRIER DISPENSE AND CLEAR TONER - A process is disclosed for the preparation of developer compositions comprising: providing a first developer including carrier and a first toner comprised of resin, pigment, polyolefin, a first compatibilizer, a first charge control agent, and a first metal oxide surface additive; and, adding thereto a second developer including carrier, and a second toner, second compatibilizer, a second charge control agent, and a second metal oxide surface additive. | 05-08-2014 |
Mark James Hirsch, Fairport, NY US
Patent application number | Description | Published |
---|---|---|
20140106276 | DISPENSING TONER ADDITIVES VIA CARRIER DISPENSE - The present disclosure provides a process for the preparation of developer compositions comprising: a first developer comprised of carrier and toner comprised of resin, pigment, polyolefin, compatibilizer, charge control agent, and metal oxide surface additive, and adding thereto a second developer comprised of carrier, and second compatibilizer, charge control agent, and metal oxide surface additive. The second developer can be directly dispensed into a developer housing. | 04-17-2014 |
Matthew Hirsch, Stoneham, MA US
Patent application number | Description | Published |
---|---|---|
20140263359 | POLARIZATION SAMPLE GEOMETRY - A carrier for a sample of highly polarized material includes a shell having a radially exterior surface and a radially interior surface, and a sample of highly polarized material interiorly adjacent to the radially interior surface. The shell may be substantially cylindrical, and may be constructed from a magnetic or non-magnetic material. The sample of highly polarized material may comprise a methyl rotor group material. The sample of highly polarized material may comprise pyruvic acid or an acetic acid. The sample of highly polarized material may be co-axial with the cylindrical shell. The sample of highly polarized material may be bonded or frozen to the radially interior surface of the shell. The carrier may further comprise a wad of material that forms a volume and contacts an axially proximate end of at least one of the shell or the sample. | 09-18-2014 |
20150075183 | POLARIZATION INSERT FOR A CRYOGENIC REFRIGERATOR - A method includes pneumatically expelling a sample of magnetically polarized material along a pneumatic flow path from a cryogenic environment. | 03-19-2015 |
Matthew Hirsch, Somerville, MA US
Patent application number | Description | Published |
---|---|---|
20090003515 | METHOD OF AND SYSTEM FOR VARIABLE PITCH COMPUTED TOMOGRAPHY SCANNING FOR BAGGAGE SCREENING - A method of and a system for variable pitch CT scanning for baggage screening and variable pitch image reconstruction are disclosed. The method comprises decelerating conveyor belt speed when additional time is needed to render a decision on a complex bag; accelerating conveyor belt speed to its normal speed when decisions are reached on undecided bags; generating cone-beam projection data at variable scanning pitch corresponding to variable conveyor belt speed; computing a tilt angle and a distance offset for each tilted slice using the pitch values at which the cone-beam projection data is acquired for that tilted slice; generating fan-beam projection data for each tilted slice using the tilted angle and the distance offset; generating correction projection data to compensate for the error between the source trajectory and the tilted reconstruction plane; generating the corrected fan-beam projection data by adding the correction projection data to the fan-beam projection data; reconstructing tilted slices using the corrected fan-beam projection data; and interpolating the reconstructed tilted slices into axial slices. | 01-01-2009 |
20110019056 | Bi-Directional Screen - A bidirectional screen alternately switches between a display mode showing conventional graphics and a capture mode in which the LCD backlight is disabled and the LCD displays a pinhole array or a tiled-broadband code. A large-format image sensor is placed behind the liquid crystal layer. Together, the image sensor and LCD function as a mask-based light field camera, capturing an array of images equivalent to that produced by an array of cameras spanning the display surface. The recovered multi-view orthographic imagery is used to passively estimate the depth of scene points from focus. | 01-27-2011 |
20120140131 | Content-Adaptive Parallax Barriers for Automultiscopic Display - In exemplary implementations of this invention, two LCD screens display a multi-view 3D image that has both horizontal and vertical parallax, and that does not require a viewer to wear any special glasses. Each pixel in the LCDs can take on any value: the pixel can be opaque, transparent, or any shade between. For regions of the image that are adjacent to a step function (e.g., a depth discontinuity) and not adjacent to a sharp corner, the screens display local parallax barriers comprising many small slits. The barriers and the slits tend to be oriented perpendicular to the local angular gradient of the target light field. In some implementations, the display is optimized to seek to minimize the Euclidian distance between the desired light field and the actual light field that is produced. Weighted, non-negative matrix factorization (NMF) is used for this optimization. | 06-07-2012 |
20130176704 | Polarization fields for dynamic light field display - In exemplary implementations of this invention, a flat screen device displays a 3D scene. The 3D display may be viewed by a person who is not wearing any special glasses. The flat screen device displays dynamically changing 3D imagery, with a refresh rate so fast that the device may be used for 3D movies or for interactive, 3D display. The flat screen device comprises a stack of LCD layers with two crossed polarization filters, one filter at each end of the stack. One or more processors control the voltage at each pixel of each LCD layer, in order to control the polarization state rotation induced in light at that pixel. The processor employs an algorithm that models each LCD layer as a spatially-controllable polarization rotator, rather than a conventional spatial light modulator that directly attenuates light. Color display is achieved using field sequential color illumination with monochromatic LCDs. | 07-11-2013 |
20140063077 | Tensor Displays - In exemplary implementations of this invention, an automultiscopic display device includes (1) one or more spatially addressable, light attenuating layers, and (2) a controller which is configured to perform calculations to control the device. In these calculations, tensors provide sparse, memory-efficient representations of a light field. The calculations include using weighted nonnegative tensor factorization (NTF) to solve an optimization problem. The NTF calculations can be sufficiently efficient to achieve interactive refresh rates. Either a directional backlight or a uniform backlight may be used. For example, the device may have (1) a high resolution LCD in front, and (2) a low resolution directional backlight. Or, for example, the device may have a uniform backlight and three or more LCD panels. In these examples, all of the LCDs and the directional backlight (if applicable) may be time-multiplexed. | 03-06-2014 |
20140300869 | Methods and Apparatus for Light Field Projection - In exemplary implementations of this invention, light from a light field projector is transmitted through an angle-expanding screen to create a glasses-free, 3D display. The display can be horizontal-only parallax or full parallax. In the former case, a vertical diffuser may positioned in the optical stack. The angle-expanding screen may comprise two planar arrays of optical elements (e.g., lenslets or lenticules) separated from each other by the sum of their focal distances. Alternatively, a light field projector may project light rays through a focusing lens onto a diffuse, transmissive screen. In this alternative approach, the light field projector may comprise two spatial light modulators (SLMs). A focused image of the first SLM, and a slightly blurred image of the second SLM, are optically combined on the diffuser, creating a combined image that has a higher spatial resolution and a higher dynamic range than either of two SLMs. | 10-09-2014 |
Matthew Louis Hirsch, Chapel Hill, NC US
Patent application number | Description | Published |
---|---|---|
20140271551 | Synthetic Adeno-Associated Virus Inverted Terminal Repeats - This invention relates to synthetic adeno-associated virus (AAV) inverted terminal repeats (ITRs) that exhibit altered activities compared to a naturally occurring AAV ITR and methods of using the same for delivery of nucleic acids to a cell or a subject. The synthetic ITRs provide a larger packaging capacity and the ability to manipulate activities such as transduction efficiency, cellular response to transduction, and transcription. | 09-18-2014 |
Michael J. Hirsch, Orlando, FL US
Patent application number | Description | Published |
---|---|---|
20100223086 | Determining A Course Of Action While Managing Resources - According to one embodiment, determining a course of action includes receiving a problem description describing an optimization problem. The optimization problem comprises resources and adversarial objects. A resource performs an action, and an adversarial object performs a reaction in response to the action. The optimization problem is decomposed into sub-problems, where each sub-problem corresponds to an adversarial object. Each sub-problem is solved to yield an optimal sub-solution. It is determined whether there are one or more resource conflicts among the sub-solutions. A resource conflict occurs if a resource is required to perform more than one action at a stage. If there are one or more resource conflicts, a fixing procedure is applied to address the resource conflicts. | 09-02-2010 |
Michael J. Hirsch, St. Petersburg, FL US
Patent application number | Description | Published |
---|---|---|
20100182969 | Optimization Strategies For Resource Management And Course Of Action Analysis - A method for allocating resources includes receiving one or more parameters associated with an object of interest. At least one of the parameters corresponds to a probability that the object of interest is participating in a predetermined situation of interest. The method also includes calculating a plurality of values, based at least in part on the parameters, and selecting, based at least in part on the calculated values, one or more operations to be performed involving the object of interest. In addition the method includes generating an instruction based at least in part on the operation to be performed transmitting the instruction to an operational resource. | 07-22-2010 |
Michael Jacob Hirsch, Oldsmar, FL US
Patent application number | Description | Published |
---|---|---|
20080319558 | Global optimization by continuous greedy randomized adaptive search procedure - Disclosed are method and apparatus for generating a global minimum value of a function representing a characteristic of a system comprising at least one object, wherein the function is based at least in part on a set of data elements within a bounded domain. At an initial randomly chosen data element, the method comprises generating a local minimum by a sequence comprising multiple iterations of a construction phase followed by a local-improvement phase. A set of local minima are generated at a set of initial randomly chosen data elements. The global minimum is the minimum of the local minima within the bounded domain. | 12-25-2008 |
20080319713 | Sensor registration by global optimization procedures - Disclosed are method and apparatus for registering multiple sensors collecting data from multiple objects. Sensor registration is decomposed into a two-step procedure. The first step corrects systematic errors. The second step assigns objects measured by one sensor to objects measured by a second sensor. Systematic errors are corrected by generating the global minimum of a systematic error function. One embodiment for generating the global minimum uses a Continuous Greedy Randomized Adaptive Search Procedure. | 12-25-2008 |
20100076726 | Sensor Registration by Global Optimization Procedures - Disclosed are method and apparatus for registering multiple sensors collecting data from multiple objects. Sensor registration is decomposed into a two-step procedure. The first step corrects systematic errors. The second step assigns objects measured by one sensor to objects measured by a second sensor. Systematic errors are corrected by generating the global minimum of a systematic error function. One embodiment for generating the global minimum uses a Continuous Greedy Randomized Adaptive Search Procedure. | 03-25-2010 |
Nicholas J. Hirsch, Wind Lake, WI US
Patent application number | Description | Published |
---|---|---|
20090060477 | FOOD WASTE DISPOSER WITH PWM BASED CONTROL OF GRINDING PROFILE - A food waste disposer has a motor driven with pulse width modulation (“PWM”). A grinding profile is controlled based on PWM values of the PWM controller driving the motor. In an aspect, controlling the grinding profile includes varying the speed of the motor based on the PWM values. In an aspect, the grinding profile is initiated after the food waste disposer is started and a PWM value exceeds a set value indicating the presence of a grinding load in a grinding section of the food waste disposer. In an aspect, it is determined that the grinding load has been sufficiently ground once the PWM value does not exceed a first set value after the grinding profile has been initiated. In an aspect, corrective action is initiated when the PWM value exceeds the set value after a predetermined period of time. | 03-05-2009 |
20140339345 | Counter Top Food Waste Disposer - A counter top food waste disposer in accordance with an aspect of the present disclosure includes a food conveying section, a motor section and a grind and discharge section disposed between the food conveying section and the motor section. In an aspect, the food waste disposer also includes a discharge area in which a container is removably receivable. When the container is received in the discharge area, during operation of the food waste disposer food waste is dischargeable from a discharge outlet of a discharge section into the container. In an aspect, a hose is removably receivable in the discharge area when the container is not present and food waste is discharged through the hose when it is received in the discharge area. In an aspect, the food waste disposer includes a water reservoir from which water can be introduced into the food waste disposer. | 11-20-2014 |
Peter G. Hirsch, Sands Point, NY US
Patent application number | Description | Published |
---|---|---|
20140279357 | Methods, Systems, and Devices for Managing Financial Toxicity - A system that analyzes toxic flow, retains the toxic flow with a dealer, and rebates all or a partial percentage of the toxic flow to liquidity providers in the market, The system allows clients and dealers can be identified by a number or code, and temporarily retains toxicity with the dealers until a predetermined amount of time and/or number of trades elapses. The dealers can then rebate back to the system any net toxicity beyond a random distribution, and the system can distribute any net toxicity beyond the random distribution to the liquidity providers. Buyers and sellers therefore receive a better price, and liquidity providers can operate with the comfort of knowing that their transactions will involve no toxicity above a random distribution. | 09-18-2014 |
Raphael Hirsch, Pittsburgh, PA US
Patent application number | Description | Published |
---|---|---|
20090214092 | METHOD OF ASSESSING A BODY PART - A method of assessing a body part includes obtaining two or more types of data through a combination of two or more of the following four imaging modalities: (1) obtaining surface topography data of the body part, (2) obtaining thermographic data of the body part, (3) obtaining range of motion data for the body part, and (4) obtaining spectral data of light reflected from the body part. The two or more types of data are integrated to allow them to be interacted with simultaneously, and the body part is assessed based on the integrated data. | 08-27-2009 |
20090216130 | METHOD OF ASSESSING LOCALIZED SHAPE AND TEMPERATURE OF THE HUMAN BODY - A method of objectively quantifying assessments of joints having arthritis for purposes of assessment, diagnosis and treatment. The objective measurements utilize known imaging modalities including 3D scanning, thermal imaging, visible and near-infrared imaging and two-dimensional imaging to quantify swelling, heat distribution, erythema, and range or motion. The objective measurements can be combined in various ways to assess the extent of the disease and can be used to adjust treatment protocols. | 08-27-2009 |
20110045507 | FSTL-1 AS A BIOMAKER OF INFLAMMATION - The invention provides methods and kits for diagnosing severity of particular types of inflammatory diseases, such as rheumatic diseases, by assessing protein levels of follistatin-like protein 1 (FSTL-1). The level of FSTL-1 protein present in the serum or synovial fluid of individuals suspected of having certain inflammatory disease (e.g, rheumatoid arthritis) is positively correlated with the severity of the disease. | 02-24-2011 |
20110274698 | Immunomodulation Of Inflammatory Conditions Utilizing Follistatin-Like Protein-1 And Agents That Bind Thereto - Follistatin-like protein (FSTL-1) is a secreted glycoprotein of unknown function, first isolated from mouse osteoblastic cells as a transforming growth factor-β1-inducible gene. The inventors have discovered that FSTL-1 is a proinflammatory mediator. As such, the invention provides for composition and methods of using agents that bind to FSTL-1 to modulate various types of inflammation (e.g., autoimmune diseases). Inhibitors and antagonists of FSTL-1, particularly antibodies or antibody fragments, may be used to treat conditions related to inflammation, such as arthritis. In addition, the inventors have discovered that FSTL-1 has a role in the Th17 pathway. Accordingly, the invention provides for compositions and methods of using agents which bind to FSTL-1 to modulate the generation of Th17 cells. Such agents are useful for delaying development of and treating diseases associated with undesired production of Th17 cells, such as autoimmune diseases. Furthermore, since FSTL-1 is a proinflammatory mediator with a role in cancer, the invention provides for compositions and methods of using a pharmaceutical composition of FSTL-1 to delay development of or treat cancer. | 11-10-2011 |
20130149712 | FOLLISTATIN-LIKE PROTEIN-1 AS A BIOMARKER FOR INFLAMMATORY DISORDERS - The present invention relates to methods and compositions for diagnosis of inflammatory disorders, and in non-limiting embodiments, of inflammatory disorders associated with elevated interleukin-1β (“IL-1β”), based on increased levels of follistatin-like protein 1 (“FSTL-1”). In particular non-limiting embodiments, the invention further provides for methods of identifying subjects with systemic onset juvenile idiopathic arthritis (“SOJIA”) who are at increased risk for developing macrophage activation syndrome (“MAS”) comprising detecting, in said subjects, hyper-increased levels of FSTL-1. In additional non-limiting embodiments, the invention provides for methods of identifying subjects with Kawasaki disease who are at increased risk of developing aortic aneurysms comprising detecting, in said subjects, hyper-increased levels of FSTL-1. | 06-13-2013 |
Raphael Hirsch, Iowa City, IA US
Patent application number | Description | Published |
---|---|---|
20130011863 | Follistatin-Like Protein-1 as a Biomarker for Sepsis - The present invention relates to methods and kits for diagnosing systemic inflammatory response syndrome or sepsis using levels of FSTL-1. | 01-10-2013 |
Robert L. Hirsch, Alexandria, VA US
Patent application number | Description | Published |
---|---|---|
20100202582 | SYSTEM AND METHOD FOR STORING ENERGY IN A NUCLEAR POWER PLANT - A method of storing heat includes moving a portion of a heated fluid from at least one reactor core to at least one tank having solid media, storing heat from the portion of the heated fluid in the solid media, and transferring the stored heat from the solid media to a fluid that can be used by a power plant to generate electrical energy. A system for storing heat in a nuclear power plant includes at least one tank comprising solid media structured and arranged to store heat and an arrangement structured and arranged to pass a first fluid through the at least one tank, transfer heat from the first fluid to the solid media, store the heat in the solid media, and transfer the heat from the solid media to a second fluid. This Abstract is not intended to define the invention disclosed in the specification, nor intended to limit the scope of the invention in any way. | 08-12-2010 |
20140334593 | SYSTEM AND METHOD FOR STORING ENERGY IN A NUCLEAR POWER PLANT - A method for storing the energy of a nuclear power plant in which the nuclear core is cooled by gases or liquid heat transfer media. The hot heat transfer liquid is stored directly in storage tanks. When needed, it is used for heating a power plant. The heat of a compressed gas heat transfer medium such as helium is stored by passing the compressed gas through tanks filled with heat-resistant solids and recovered by passing the same type of gas in a second circuit in a reverse direction. Through the hot tanks to the power plant and back. This Abstract is not intended to define the invention disclosed in the specification, nor intended to limit the scope of the invention in any way. | 11-13-2014 |
Robert S. Hirsch, Troy, NY US
Patent application number | Description | Published |
---|---|---|
20140105813 | HYDROGEN RECYCLER WITH OXYGEN REACTOR - A hydrogen recycling system for a controlled atmosphere unit operation with an exhaust vent and an inlet port includes: a hydrogen recycle unit in fluid communication with the exhaust vent and in fluid communication with the inlet port; and an oxygen reactor being located between the controlled atmosphere unit operation and said hydrogen recycle unit and in fluid communication with the controlled atmosphere unit operation and said hydrogen recycle unit. | 04-17-2014 |
20140290765 | GAS RECYCLING SYSTEM FOR A CONTROLLED ATMOSPHERE UNIT OPERATION - A gas recycling system for a controlled atmosphere furnace includes a controlled atmosphere furnace having a product entry, a product exit, a process gas inlet adjacent said product exit, and a spent gas outlet adjacent said product entry. A spent gas recycler is operationally connected to the spent gas outlet. The recycler produces a recycled process gas stream and a waste gas stream. The recycled process gas stream is returned to the controlled atmosphere furnace. The waste gas stream is returned to the controlled atmosphere furnace at a point downstream from the spent gas outlet. | 10-02-2014 |
Russel Hirsch, Cincinnati, OH US
Patent application number | Description | Published |
---|---|---|
20130295192 | METHOD TO IDENTIFY TISSUE OXYGENATION STATE BY SPECTROGRAPHIC ANALYSIS - A system and method for identifying metabolic activity within the heart muscle (myocardium). Metabolic activity is determined through spectrographic analysis of the myocardium. More particularly, oxygen saturation of the myocardium is measured through the spectrographic analysis, and metabolic activity is measured by a decrease in oxygen saturation of the myocardium over time. | 11-07-2013 |
Scott Hirsch, Boca Raton, FL US
Patent application number | Description | Published |
---|---|---|
20120260232 | SYSTEMS AND METHODS FOR A MOBILE APPLICATION DEVELOPMENT AND DEPLOYMENT PLATFORM - Systems and methods for developing, customizing, and deploying mobile device applications are provided through a mobile application development and deployment platform. Preferably, these systems and methods are implemented in an Internet based environment that allows non-technical users to build sophisticated, highly-customizable cross-platform mobile applications. The platform allows users to select, input, create, customize, and combine various content, design characteristics, and application components, such as modules, some of which make use of features and functionality associated with various mobile devices and mobile operating systems. In certain embodiments, the platform allows users to compile the mobile application for various mobile operating systems and generates a configuration file for the mobile application that can be distributed to end users for execution on various mobile devices. When the mobile application is installed on, or executed by the mobile device, the configuration file may enable the retrieval of various data associated with the mobile application. | 10-11-2012 |
20130205276 | SYSTEMS AND METHODS FOR A MOBILE APPLICATION DEVELOPMENT AND DEPLOYMENT PLATFORM - Systems and methods for developing, customizing, and deploying mobile device applications are provided through a mobile application development and deployment platform. Preferably, these systems and methods are implemented in an Internet based environment that allows non-technical users to build sophisticated, highly-customizable cross-platform mobile applications. The platform allows users to select, input, create, customize, and combine various content, design characteristics, and application components, such as modules, some of which utilize features and functionality associated with various mobile devices and mobile operating systems. In certain embodiments, the platform allows users to compile, and generate a configuration file for, the mobile application that can be distributed to end users for execution on various mobile devices and mobile operating systems. When the mobile application is installed on, or executed by the mobile device, the configuration file may enable the retrieval of various data associated with the mobile application. | 08-08-2013 |
20130205278 | SYSTEMS AND METHODS FOR A MOBILE APPLICATION DEVELOPMENT AND DEPLOYMENT PLATFORM - Systems and methods for developing, customizing, and deploying mobile device applications are provided through a mobile application development and deployment platform. Preferably, these systems and methods are implemented in an Internet based environment that allows non-technical users to build sophisticated, highly-customizable cross-platform mobile applications. The platform allows users to select, input, create, customize, and combine various content, design characteristics, and application components, such as modules, some of which utilize features and functionality associated with various mobile devices and mobile operating systems. In certain embodiments, the platform allows users to compile, and generate a configuration file for, the mobile application that can be distributed to end users for execution on various mobile devices and mobile operating systems. When the mobile application is installed on, or executed by the mobile device, the configuration file may enable the retrieval of various data associated with the mobile application. | 08-08-2013 |
20130219429 | SYSTEMS AND METHODS FOR A TELEVISION AND SET-TOP BOX APPLICATION DEVELOPMENT AND DEPLOYMENT PLATFORM - Systems and method are disclosed for creating or updating an application. An application development platform is adapted to assist a user with creating or updating an application. The platform includes tools that permit a user to determine application features for the application. A plurality of application modules associated with the application are determined. The application modules are associated with one or more customization interfaces that permit the user to customize the functionality, design and content of the application. A plurality of selections are received from the user via the one or more customization interfaces associated with the application modules. A user input is also received that identifies at least one content delivery device on which the application is to be executed. Compiled data is generated for the application based on the selections received from the user. | 08-22-2013 |
20130247005 | SYSTEMS AND METHODS FOR A MOBILE BUSINESS APPLICATION DEVELOPMENT AND DEPLOYMENT PLATFORM - Systems and methods for developing, customizing, and deploying mobile device business applications are provided through a mobile application development and deployment platform. Preferably, these systems and methods are implemented in an Internet based environment that allows non-technical users to build highly-customizable cross-platform mobile applications. The platform allows users to select, input, create, customize, and combine various content, design characteristics, database structure, and application components, such as modules, some of which allow an end user to store and access data in an end user database for business applications. In certain embodiments, the platform allows users to compile and generate a configuration file for the mobile application that can be distributed to end users for execution on various mobile devices and mobile operating systems. When the mobile application is installed on, or executed by the mobile device, the configuration file may enable the retrieval of data associated with the mobile application. | 09-19-2013 |
20130283305 | SYSTEMS AND METHODS FOR A TELEVISION AND SET-TOP BOX APPLICATION DEVELOPMENT AND DEPLOYMENT PLATFORM - Systems and method are disclosed for providing a viewer environment on a television device. An authentication component permits a viewer to access a profile on a television device having a network connection, wherein the profile includes personalization data for customizing a viewer environment. The personalization data is derived, at least in part, from the viewer's interaction with the viewer environment. Access to the profile is granted in response to determining that the login credentials received from the viewer are valid. One or more customization aspects to be incorporated into the viewer environment are determined based on the personalization data in the profile. Data is provided for rendering the viewer environment on the television device of the viewer in a manner that includes the customization aspects associated with the personalization data. | 10-24-2013 |
20130305218 | SYSTEMS AND METHODS FOR A SPECIALIZED APPLICATION DEVELOPMENT AND DEPLOYMENT PLATFORM - Systems and methods for developing, customizing, and deploying applications for devices are provided through a application development and deployment platform. Preferably, these systems and methods are implemented in an Internet based environment that allows non-technical users to build sophisticated, highly-customizable cross-platform applications. The platform allows users to select, input, create, customize, and combine various content, design characteristics, and application components, such as modules, some of which utilize features and functionality associated with various devices capable of running applications, operating systems, and app-enabled accessories. In certain embodiments, the platform allows users to compile and generate a configuration file for the application that can be distributed to end users for execution on various devices and operating systems. When the application is installed on, or executed by the device, the configuration file may enable the retrieval of various data associated with the application. | 11-14-2013 |
20140109046 | SYSTEMS AND METHODS FOR A VOICE- AND GESTURE-CONTROLLED MOBILE APPLICATION DEVELOPMENT AND DEPLOYMENT PLATFORM - Systems and methods for developing, customizing, and deploying mobile device applications through voice and/or gesture interactions are provided through a mobile application development and deployment platform. Preferably, these systems and methods are implemented in an Internet based environment that allows non-technical users to build sophisticated, highly-customizable cross-platform mobile applications. The platform allows users to use voice and/or gesture interactions to select, input, create, customize, and combine various content, design characteristics, and application components, such as modules, some of which utilize features and functionality associated with various mobile devices and mobile operating systems. In certain embodiments, the platform allows users to compile the mobile application for various mobile operating systems and generates a configuration file for the mobile application that can be distributed to end users for execution on various mobile devices. When the mobile application is installed on, or executed by the mobile device, the configuration file may enable the retrieval of various data associated with the mobile application. | 04-17-2014 |
20140281886 | SYSTEMS AND METHODS FOR CREATING OR UPDATING AN APPLICATION USING WEBSITE CONTENT - The disclosure herein relates to systems and methods for creating or updating applications using website content. An input may be received that identifies website content to be utilized in creating or updating an application. One or more application modules may to be derived from the website content. The website content may be analyzed in accordance with a rule set to detect website features associated with the website. The website features may be incorporated into the one or more application modules. The application modules may then be compiled into an application such as a mobile application or HTML 5 application. | 09-18-2014 |
20140282371 | SYSTEMS AND METHODS FOR CREATING OR UPDATING AN APPLICATION USING A PRE-EXISTING APPLICATION - The disclosure herein relates to systems and methods for creating or updating applications using content from a pre-existing application, and in particular, utilizing content of a pre-existing application to create or update mobile applications and web applications including HTML 5 applications. An input may be received that identifies a pre-existing application to be utilized in creating or updating an application. One or more application modules may be derived from the content of the pre-existing application. The application content may be analyzed in accordance with a rule set to detect application features associated with the pre-existing application. The application features may be incorporated into the one or more application modules. The application modules may then be compiled into an application such as a mobile application or HTML 5 application. | 09-18-2014 |
20150089339 | SYSTEMS AND METHODS FOR CREATING OR UPDATING AN APPLICATION USING WEBSITE CONTENT - The disclosure herein relates to systems and methods for creating or updating applications using website content. An input may be received that identifies website content to be utilized in creating or updating an application. One or more application modules may be derived from the website content. The website content may be analyzed in accordance with a rule set to detect website features associated with the website. The website features may be incorporated into the one or more application modules. The application modules may then be compiled into an application such as a mobile application or HTML 5 application. | 03-26-2015 |
Seth Stuart Hirsch, Chevy Chase, MD US
Patent application number | Description | Published |
---|---|---|
20140279640 | SYSTEMS, METHODS AND APPARATUSES FOR IDENTIFYING PERSON OF INTEREST - The present disclosure describes systems, methods, and apparatuses for identifying a person of interest. An exemplary method may comprise storing external data received from a variety external sources into a parameterized table, creating a first set of category views on the parameterized table, creating a second set of category views based at least in part on data to be derived from a traveler's personal information to be received, receiving the traveler's personal information generated by an input device and determining whether the traveler is a person of interest by evaluating the personal information against one or more pre-defined profiles using the first and second sets of category views. Each of the one or more pre-defined profiles may comprise one or more rules and a threshold value for determining a likelihood for the traveler to be matched in each of the one or more pre-defined profiles. | 09-18-2014 |
Steven B. Hirsch, Middleburg, VA US
Patent application number | Description | Published |
---|---|---|
20100040400 | KEYBOARD AND KEYS - In a preferred form, a keyboard has a single row of eight multi-position keys or groups of key elements with the letters arranged in a standard QWERTY keyboard configuration. The eight keys or key element groups correspond to the eight fingers used when touch typing; each finger operates one key, and that key contains all the letters that the finger normally accesses when touch typing on a standard QWERTY keyboard. With this design, no finger has to move to a different key or key element group while typing. In certain forms, when depressed at different locations on its key face, each key either moves straight down, or down while tilting slightly about one of a plurality of axes. Three-position keys have two tilt axes and six-position keys have five tilt axes. The switches utilize contacts located on the bottom of the switches which may be conductive or nonconductive. | 02-18-2010 |
Steven N. Hirsch, Burlington, VT US
Patent application number | Description | Published |
---|---|---|
20110314238 | COMMON MEMORY PROGRAMMING - A method for unidirectional communication between tasks includes providing a first task having access to an amount of virtual memory, blocking a communication channel portion of said first task's virtual memory, such that the first task cannot access said portion, providing a second task, having access to an amount of virtual memory equivalent to the first task's virtual memory, wherein a communication channel portion of the second task's virtual memory corresponding to the blocked portion of the first task's virtual memory is marked as writable, transferring the communication channel memory of the second task to the first task, and unblocking the communication channel memory of the first task. | 12-22-2011 |
Thomas Steven Hirsch, Bedford, MA US
Patent application number | Description | Published |
---|---|---|
20100235896 | Instrument access control system - A system for centrally managing a set of network-connected laboratory instruments is disclosed. For example, the system includes a centralized database that includes information about the instruments in the system and about the authorized users of the system. In particular, the centralized database indicates which users are authorized to use each of the instruments in the system. The database may also include information about the operations that each user is authorized to perform using the instruments and information indicating whether tests performed by each instrument must be signed using one or more electronic signatures. The system may recognize a number of “roles,” each of which is associated with a particular set of rights, and may assign one or more roles to each user. Instruments and other elements of the system may access the centralized database over a network to enforce the user rights represented by the information in the database. | 09-16-2010 |
William Hirsch, Laconia, NH US
Patent application number | Description | Published |
---|---|---|
20090266392 | Crutch cushion, crutch system and kit - A crutch cushion, a crutch cushion kit and crutch system that includes the crutch cushion. The crutch cushion includes a body having rear, front, right side, left side, top and bottom surfaces, and a hollow chamber proximate to the bottom surface. The top surface slopes downward from the front surface to the rear surface. The right and left side surfaces each have a substantially concave shape. The bottom surface has an oblong opening proximate to and dimensioned to be smaller than a dimension of the hollow chamber. | 10-29-2009 |