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Hiroyuki Nishii

Hiroyuki Nishii, Osaka JP

Patent application numberDescriptionPublished
20100098756ORAL DISINTEGRATING TABLET - An oral disintegrating tablet containing (1) D-mannitol, (2) an active ingredient, (3) one or more disintegrating agents selected from the group consisting of crospovidone and carmellose, and (4) one or more lubricants selected from the group consisting of sodium stearyl fumarate and sucrose esters of fatty acids. The oral disintegrating tablet of the present invention has some excellent properties of (1) allowing easy production in a common facility without necessitating a specialized pharmaceutical technique, (2) having an appropriate strength that does not breakdown in the process of distribution, (3) having a fast disintegrating ability in the oral cavity, and (4) also having excellent ingestion feel such as greatly reduced bitterness or gritty feel; therefore, the tablet can be suitably used as a dosage form that is suitable for aged individuals, children, and seriously ill patients.04-22-2010
20110027692PROTON-CONDUCTIVE POLYMER ELECTROLYTE MEMBRANE, METHOD OF MANUFACTURING THE PROTON-CONDUCTIVE POLYMER ELECTROLYTE MEMBRANE, AND MEMBRANE-ELECTRODE ASSEMBLY AND POLYMER ELECTROLYTE FUEL CELL USING THE PROTON-CONDUCTIVE POLYMER ELECTROLYTE MEMBRANE - A method of manufacturing a proton-conductive polymer electrolyte membrane using polyvinyl alcohol (PVA) as a base material and having excellent proton conductivity and methanol blocking properties is provided. The method includes: heat-treating a precursor membrane including PVA and a water-soluble polymer electrolyte having a proton conductive group to proceed crystallization of the PVA; and chemically crosslinking the heat-treated precursor membrane with a crosslinking agent reactive with the PVA, to form a polymer electrolyte membrane in which a crosslinked PVA is a base material and protons are conducted through the electrolyte retained in the base material. The content of a water-soluble polymer except the PVA and the water-soluble polymer electrolyte in the precursor membrane is in a weight ratio of less than 0.1 with respect to the PVA.02-03-2011
20110039185ELECTROLYTE MEMBRANE FOR POLYMER ELECTROLYTE FUEL CELL AND METHOD OF MANUFACTURING THE SAME - An electrolyte membrane (02-17-2011

Patent applications by Hiroyuki Nishii, Osaka JP

Hiroyuki Nishii, Ibaraki-Shi JP

Patent application numberDescriptionPublished
20100273260CELL CULTURE SUBSTRATE AND PROCESS FOR PRODUCING THE SAME AND METHOD FOR CULTURING CELLS - The present invention relates to a cell culture substrate in which a polymer chain having a hydrophilic skeleton is grafted onto a surface of polystyrene or poly(ε-caprolactone) having a water contact angle of from 75° to 100°. This cell culture substrate has excellent efficiency of cell culture without the necessity of immobilization and adsorption of a cell adhesion substance on a surface of a substrate.10-28-2010
20110027362TABLET HAVING IMPROVED ELUTION PROPERTIES - The present invention provides a tablet having improved dissolution property, which comprises (+)-3-{1-[3-(trifluoromethoxy)benzyl]piperidin-4-yl}-4-phenyl-3,4-dihydro-2(1H)-quinazolinone or a pharmaceutically acceptable salt thereof as an active component, and a production method thereof.02-03-2011

Patent applications by Hiroyuki Nishii, Ibaraki-Shi JP

Hiroyuki Nishii, Ootake-Shi JP

Patent application numberDescriptionPublished
20090209707IMPACT RESISTANCE IMPROVER, THERMOPLASTIC RESIN COMPOSITION, SHAPED ARTICLE AND METHOD FOR PRODUCING GRAFT COPOLYMER - Disclosed is a thermoplastic resin composition having excellent impact resistance at a low temperature, while maintaining high transparency; this thermoplastic resin composition is obtained by compounding an impact resistance improver into a thermoplastic resin, the impact resistance improver being composed of a graft copolymer which is obtained by polymerizing a vinyl monomer component in the presence of a polymer mixture containing a polymer having butadiene units as an essential component and a polymer having styrene units as an essential component, the polymer mixture containing 45 to 65% by mass of the butadiene units and 35 to 55% by mass of the styrene units.08-20-2009

Hiroyuki Nishii, Ibaraki JP

Patent application numberDescriptionPublished
20090186083METHOD FOR STABILIZATION OF ISOXAZOLE COMPOUND07-23-2009

Hiroyuki Nishii, Takatsuki JP

Patent application numberDescriptionPublished
20080311212CRYSTALLINE ISOXAZOLE DERIVATIVE AND PHARMACEUTICAL PREPARATION THEREOF - Crystalline 3-[(1S)-1-(2-fluorobiphenyl-4-yl)ethyl]-5-{[amino(morpholin-4-yl)methylene]amino}-isoxazole that exhibits the following angle of diffraction (2θ) and relative intensity in a powder X-ray diffraction pattern, is very easy to handle and stable in a process of its formulation into a pharmaceutical preparation.12-18-2008