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Hiroyuki Hirai

Hiroyuki Hirai, Kanagawa JP

Patent application numberDescriptionPublished
20090074671DRUG-IMMOBILIZED INORGANIC NANOPARTICLE - An object of the present invention is to provide a composite of an inorganic nanoparticle with a medicinal compound (i.e., an active substance), and to provide a method for producing the inorganic nanoparticle composite, which is highly versatile and convenient. The present invention provides an active substance-immobilized inorganic nanoparticle wherein an active substance is immobilized through physical adsorption on the surface of an inorganic nanoparticle of 1 to 500 nm in average particle size.03-19-2009
20090130022MRI CONTRAST MEDIUM CONTAINING LIPOSOMES - A liposome containing a phosphatidylcholine and a phosphatidylserine in combination as membrane components at a phosphatidylcholine:phosphatidylserine molar ratio of 3:1 to 1:2, and said liposome containing superparamagnetic particles having a mean particle size not less than 1 nm and not more than 50 nm. A means for selectively accumulating an MRI contrast medium in a lesion of a vascular disease caused by abnormal proliferation of vascular smooth muscle cells such as arteriosclerosis and restenosis after PTCA is provided.05-21-2009
20090233086METAL OXIDE MICROPARTICLES, TRANSPARENT CONDUCTIVE FILM, AND DISPERSION - The present invention provides a transparent conductive film including metal oxide microparticles having a mean particle diameter of 2 nm to 1,000 nm and silver nanowires having a minor axis diameter of 2 nm to 100 nm and an aspect ratio of 10 to 200.09-17-2009
20090242231SILVER NANOWIRE, PRODUCTION METHOD THEREOF, AND AQUEOUS DISPERSION - A method for producing a silver nanowire including heating a silver complex in a water solvent at a temperature equal to or below the boiling point of the water solvent, and the silver nanowire produced by the method.10-01-2009
20090311530SILVER NANOWIRE, PRODUCTION METHOD THEREOF, AND AQUEOUS DISPERSION - To provide a method for producing a silver nanowire, including heating a silver complex in an aqueous solvent at a temperature equal to or below the boiling point of the aqueous solvent in the presence of at least one of a hydroxyketone compound and a hydroxylamine compound, and a silver nanowire obtained by the method.12-17-2009
20110061728PROTECTIVE FILM AND FRONT SHEET FOR SOLAR CELL - Provided is a protective film having high transparency, high ultraviolet absorption ability, high weatherability and flexibility, and not being peeled from its coating layers from a plastic film even if irradiated with ultraviolet. the protective film. The protective film comprises a plastic film and a coating layer on the surface of the plastic film, wherein the coating layer comprises a binder and core-shell type zinc oxide particles dispersed in the binder, the core-shell type zinc oxide particles have an average particle size of 50 nm or less and comprises a shell having a thickness of 1.5 nm to 20 nm.03-17-2011

Patent applications by Hiroyuki Hirai, Kanagawa JP

Hiroyuki Hirai, Ashigarakami-Gun JP

Patent application numberDescriptionPublished
20090152506PROCESS FOR PRODUCING ORIENTED INORGANIC CRYSTALLINE FILM, AND SEMICONDUCTOR DEVICE USING THE ORIENTED INORGANIC CRYSTALLINE FILM - In a process for producing an oriented inorganic crystalline film, a non-monocrystalline film containing inorganic crystalline particles is formed on a substrate by a liquid phase technique using a raw-material solution which contains a raw material and an organic solvent, where the inorganic crystalline particles have a layered crystal structure and are contained in the raw material. Then, the non-monocrystalline film is crystallized by heating the non-monocrystalline film to a temperature equal to or higher than the crystallization temperature of the non-monocrystalline film so that part of the inorganic crystalline particles act as crystal nuclei.06-18-2009
20100129280BiMO PARTICLE MANUFACTURING METHOD AND PHOTOCONDUCTIVE LAYER - A method for manufacturing a BiMO particle (M is either one of Si, Ge, Ti, and Sn), in which at least one type of compound selected from the group consisting of a silicon compound, a germanium compound, a titanium compound, and a tin compound is reacted with a bismuth compound by agitating and mixing the compounds in an alkali water solution in the presence of an amino compound.05-27-2010
20100260693COSMETIC COMPOSITION - A cosmetic composition contains star-shaped zinc oxide particles each having a star shape, and containing zinc oxide as a main substance thereof.10-14-2010
20110059020LIPOSOME COMPOSITION, AND DIAGNOSTIC CONTRAST AGENT, THERAPEUTIC ENHANCER, AND PHARMACEUTICAL COMPOSITION USING THE SAME - To provide a liposome composition, which contains at least one liposome; gas entrapped in the liposome, and at least one metal oxide particle encapsulated in or adsorbed on the liposome, wherein the liposome composition satisfies a ratio B/A of 0.01 to 5, where A is a volume of the gas contained in the liposome on the basis of micro liter, and B is a mass of the at least one metal oxide particle contained in the liposome on the basis of milligram.03-10-2011
20110059024LIPOSOME COMPOSITION, AND DIAGNOSTIC CONTRAST AGENT, THERAPEUTIC ENHANCER, AND PHARMACEUTICAL COMPOSITION USING THE SAME - To provide a liposome composition, which contains at least one liposome, gas entrapped in the liposome, and at least one fullerene encapsulated in or adsorbed on the liposome.03-10-2011

Patent applications by Hiroyuki Hirai, Ashigarakami-Gun JP

Hiroyuki Hirai, Kanagawa-Ken JP

Patent application numberDescriptionPublished
20100276003LAYERED FILM AND MANUFACTURING METHOD THEREOF, PHOTOELECTRIC CONVERSION DEVICE AND MANUFACTURING METHOD THEREOF, AND SOLAR CELL APPARATUS - Using a manufacturing method which includes a process (A) for forming a particle layer of a plurality of one or more types of particles consisting mainly of a metal oxide and/or a metal hydroxide, and a process (B) for forming, using a reaction solution which includes one or more types of metal ions, a metal oxide layer consisting mainly of an oxide of the one or more types of metal ions on the particle layer so as to cover the particle layer without any cracks by a liquid phase method under a pH condition in which at least a portion of the plurality of particles remains without being dissolved by the reaction solution, a layered film having a layered structure of the particle layer and the metal oxide layer is manufactured.11-04-2010

Hiroyuki Hirai, Kawagoe-Shi JP

Patent application numberDescriptionPublished
20100015643METHOD OF QUANTITATIVE DETERMINATION OF ANTIGEN PROTEIN AND QUANTITATIVE DETERMINATION KIT THEREFOR - There is provided a method of quantitative determination using a flow cytometer, with which quantitative determination of cell surface protein can be effected more accurately than with current methods. The inventors have achieved the present invention by providing a method of quantitative determination of sites, per cell of a test sample, at which an antibody is bound to an antigen protein (sites/cell), characterized by preparing a calibration curve on the basis of fluorescent intensities obtained through measuring with a flow cytometer the amount of labeled antibodies against antigen protein which are bound to two or more groups of beads carrying known and different amounts of the antigen protein, and numeric values of the known amounts of the antigen protein, and further by measuring, with the flow cytometer, labeled antibodies against antigen protein after they have been reacted with test cells derived from a blood sample of a test subject, whereby digitalization is effected through comparison and conversion between the calibration curve and a fluorescence intensity obtained.01-21-2010

Hiroyuki Hirai, Minami-Ashigara-Shi JP

Patent application numberDescriptionPublished
20090029481Method for separating target component using magnetic nanoparticles - An object to be achieved by the present invention is to provide a method for determining the amount of a component contained in a specific lipoprotein fraction in a biological sample using an automatic analyzer, without the requirement of a step of fractionating a sample by centrifugation. The present invention provides a method for separating a target component in a biological sample, which comprises the steps of: (1) causing a biological sample to come into contact with independently dispersed magnetic nanoparticles having a particle size of 50 nm or less, which have anionic functional groups on their surfaces, so as to form an agglutinate of the magnetic nanoparticles and biomolecules capable of interacting with the magnetic nanoparticles; and (2) collecting the agglutinate by an external magnetic field.01-29-2009
20090039316DOPED-TYPE METAL SULFIDE PHOSPHOR NANOPARTICLE, DISPERSION THEREOF, AND METHOD FOR PRODUCING THE SAME - A doped-type metal sulfide phosphor nanoparticle, whose surface is modified with a surface modifier, the surface modifier being a compound of formula [I]:02-12-2009

Patent applications by Hiroyuki Hirai, Minami-Ashigara-Shi JP