| Patent application number | Description | Published |
| 20080237039 | EXTRACELLULAR POTENTIAL SENSING ELEMENT, DEVICE FOR MEASURING EXTRACELLULAR POTENTIAL, APPARATUS FOR MEASURING EXTRACELLULAR POTENTIAL AND METHOD OF MEASURING EXTRACELLULAR POTENTIAL BY USING THE SAME - A sensing element for measuring extracellular potential including a substrate, a well provided in a substrate, a guide section provided on the wall of the well, and a detective electrode formed at a lower surface of the substrate. The guide section is for guiding drug. The well is provided at the bottom with a depression, and a first throughhole penetrating through the depression and the lower surface of the substrate. The well is for mixing a subject cell, a culture solution and the drug together. The above-configured sensing element accurately measures a change generated by a subject cell. | 10-02-2008 |
| 20080257726 | EXTRACELLULAR POTENTIAL SENSING ELEMENT, DEVICE FOR MEASURING EXTRACELLULAR POTENTIAL, APPARATUS FOR MEASURING EXTRACELLULAR POTENTIAL AND METHOD OF MEASURING EXTRACELLULAR POTENTIAL BY USING THE SAME - A sensing element for measuring extracellular potential including a substrate, a well provided in a substrate, a guide section provided on the wall of the well, and a detective electrode formed at a lower surface of the substrate. The guide section is for guiding drug. The well is provided at the bottom with a depression, and a first throughhole penetrating through the depression and the lower surface of the substrate. The well is for mixing a subject cell, a culture solution and the drug together. The above-configured sensing element accurately measures a change generated by a subject cell. | 10-23-2008 |
| 20080257727 | EXTRACELLULAR POTENTIAL SENSING ELEMENT, DEVICE FOR MEASURING EXTRACELLULAR POTENTIAL, APPARATUS FOR MEASURING EXTRACELLULAR POTENTIAL AND METHOD OF MEASURING EXTRACELLULAR POTENTIAL BY USING THE SAME - A sensing element for measuring extracellular potential including a substrate, a well provided in a substrate, a guide section provided on the wall of the well, and a detective electrode formed at a lower surface of the substrate. The guide section is for guiding drug. The well is provided at the bottom with a depression, and a first throughhole penetrating through the depression and the lower surface of the substrate. The well is for mixing a subject cell, a culture solution and the drug together. The above-configured sensing element accurately measures a change generated by a subject cell. | 10-23-2008 |
| 20080293128 | SENSOR OF PYROPHOSPHATE AND SNP TYPING SENSOR USING THE SAME - A sensor of pyrophosphate which can detect pyrophosphate conveniently with high sensitivity in a method for measuring pyrophosphate in SNP typing utilizing a primer extension reaction is provided. | 11-27-2008 |
| 20090035846 | DEVICE FOR MEASURING EXTRACELLULAR POTENTIAL AND METHOD OF MANUFACTURING DEVICE - A device for measuring an extracellular potential of a test cell includes a substrate having a well formed in a first surface thereof and a first trap hole formed therein. The well has a bottom. The first trap hole includes a first opening formed in the bottom of the well and extending toward a second face of the substrate, a first hollow section communicating with the first opening via a first connecting portion, and a second opening extending reaching the second surface and communicating with the first hollow section via a second connecting portion. The first connecting portion has a diameter smaller than a maximum diameter of the first hollow section, greater than a diameter of the second connecting portion, and smaller than a diameter of the test cell. The device can retain the test cell securely and accept chemicals and the test cell to be put into the device easily. | 02-05-2009 |
| 20090211922 | ELECTRODE PLATE FOR ELECTROCHEMICAL MEASUREMENTS, APPARATUS FOR ELECTROCHEMICAL MEASUREMENTS HAVING THE ELECTRODE PLATE FOR ELECTROCHEMICAL MEASUREMENTS, AND METHOD OF THE QUANTITATIVE DETERMINATION OF A TARGET SUBSTANCE USING THE ELECTRODE PLATE FOR ELECTROCHEMICAL MEASUREMENTS - An electrode plate for electrochemical measurements capable of measuring the concentration of a target substance included in a sample solution with favorable accuracy and high sensitivity is provided | 08-27-2009 |
| 20090239033 | DIAPHRAGM AND DEVICE FOR MEASURING CELLULAR POTENTIAL USING THE SAME, MANUFACTURING METHOD OF THE DIAPHRAGM - A diaphragm is formed by etching a substrate. This substrate has a first surface provided with a depression by isotropic dry etching, and a second surface opposite the first surface. Furthermore, a through-hole is formed from the depression to the second surface by anisotropic dry etching. The depression and the through-hole are formed by using one resist mask. The depression has a hemispherical shape or a semi-elliptical spherical shape. | 09-24-2009 |
| 20090275852 | EXHALED BREATH ANALYSIS METHOD - Handling of the condensate collecting vessel in conventional breath analysis apparatuses having a cold condensation mechanism is complicated, and time consuming. | 11-05-2009 |
| 20100101965 | METHOD FOR DETECTING OR QUANTIFYING TARGET SUBSTANCE USING APPARATUS FOR ELECTROCHEMICAL MEASUREMENTS, APPARATUS FOR ELECTROCHEMICAL MEASUREMENTS, AND ELECTRODE PLATE FOR ELECTROCHEMICAL MEASUREMENTS - To provide an electrode plate for electrochemical measurements that enables detecting and quantifying the concentration of a target substance contained in a sample solution with rapidity and favorable sensitivity using an apparatus for electrochemical measurements is objected to. | 04-29-2010 |
| 20100113981 | SKIN INCISION INSTRUMENT AND METHOD FOR INCISING SKIN WITH THE SAME - Provided are skin incision instrument to efficiently incise minimal portions and a method for incising skin with the skin incision instrument. The skin incision instrument according to the present invention comprises a holder, a needle, a needle drive unit, a skin expander, and a reader, wherein the needle and the skin expander are mounted at an end of the holder, the needle drive unit is mounted in the holder, the needle drive unit is capable of forming an incision portion in a skin caused to contact the end of the holder by moving the needle, the skin expander is capable of expanding skin at both sides of the linear incision portion away from the linear incision portion in a direction to expand the linear incision portion, and the reader determines position of the skin expander by rotating the skin expander around the needle in order to adjust an angle to 45 degrees or more and 90 degrees or less wherein the angle is a smaller angle among angles formed by the representative line connecting both ends of the linear incision portion and the direction to expand skin at both sides of the linear incision portion with the skin expander, and minimal portions are efficiently incised. | 05-06-2010 |
| 20100116068 | METHOD FOR COLLECTING GASEOUS SAMPLE - The present invention of collecting gaseous sample employs the sealable container, the inlet mounted at a part of the container, the outlet mounted at the other part of the container, the atomizing electrode mounted in the container, the primary refrigerator mounted at adjacent to the atomizing electrode, the opposite electrode mounted in the container, the acicular capture electrode mounted at adjacent to the opposite electrode, and the secondary refrigerator mounted at adjacent to the capture electrode. Charged microparticles are prepared by chilling gaseous sample and producing condensate of the same. Such charged microparticles are collected by the capture electrode with static electricity, and they are condensed by chilling them. This method prevents the capture electrode from spreading solution thereon. | 05-13-2010 |
| 20100133122 | INSTRUMENT AND SYSTEM FOR PHARMACOLOGIC MEASUREMENT AND WELL VESSEL USED THEREIN - An instrument is provided for pharmacologic measurement capable of detecting a very small and short time change in electric signal caused by a pharmacologic action of a biologic specimen with quickness and a high sensitivity by steeply decreasing an external disturbance component mixed into the system while dropping/exchange of medicinal solutions is conducted in a batch mode. The pharmacologic measurement instrument detects a change in electric signal caused by a pharmacologic action or electrophysiologic action of a biologic specimen, and includes an electrically conductive box having an opening section at the top surface thereof and a well vessel disposed in the opening section thereof, wherein the well vessel includes a base having recesses in which the biologic specimens are put; measurement electrodes formed on the bottom surfaces of the respective recesses; and reference electrodes electrically insulated from the respective measurement electrodes, and the reference electrodes together with the electrically conductive box electrostatically shields the well vessel. | 06-03-2010 |
| 20100137742 | SKIN INCISION INSTRUMENT AND METHOD FOR INCISING SKIN WITH THE SAME - Provided are skin incision instrument to efficiently incise minimal portions and a method for incising skin with the skin incision instrument. The skin incision instrument according to the present invention comprises a holder, a needle, a needle drive unit, two or more skin expander sets, and a reader, wherein the skin expander sets comprise a first skin expander and a second skin expander; the first skin expander and the second skin expander are capable of expanding skin at both sides of the linear incision portion away from the linear incision portion and expanding the linear incision portion in a direction to expand the linear incision portion; and, minimal portions are efficiently incised by selecting a single skin expander set from two or more of the skin expander set based on the direction of the linear incision portion, such that an angle is adjusted to 45 degrees or more and 90 degrees or less wherein the angle is formed by the direction of the linear incision portion read by the reader and the direction to expand the skin by the single skin expander set. | 06-03-2010 |
| 20100147682 | PROBE FOR MEASURING ELECTRIC POTENTIAL OF CELL - A probe for measuring an electric potential of a cell includes a plate having a surface having a first cavity provided therein, and a sensor element provided in the first cavity. A second cavity is provided in the bottom surface of the first cavity. The first flow passage having first and second openings is provided in the plate. The first and second openings of the first flow passage open to the second cavity and outside the plate, respectively. The sensor element includes a thin plate, and a supporting substrate provided around the thin plate and in the first cavity of the plate. The thin plate has a through-hole therein having a first opening and a second opening communicating with the second cavity of the plate. The first flow passage allows fluid to flow therein. A sucking device is coupled with the second opening of the first flow passage as to suck the fluid flowing in the first flow passage. This probe can measure an electric potential of a cell floating in solution as it is in this environment. | 06-17-2010 |
| 20100206959 | CHEMICAL SUBSTANCE CONCENTRATION METHOD - An electrostatic spraying device for use in a chemical substance concentrating method, where the device includes a vessel, an injection port, a cooling part, an atomizing electrode section, and a unit for recovery of the chemical substance in the counter electrode section. Furthermore, the chemical substance concentration method includes the steps of: injecting a sample gas; producing a first condensate liquid from the sample gas; producing first charged fine particles from the first condensate liquid; producing second charged fine particles by mixing the first charged fine particles with the sample gas; and recovering the first charged fine particles and the second charged fine particles. According to a series of the operation described above, the chemical substances in the sample gas can be concentrated in a simple and efficient manner. | 08-19-2010 |
| 20100213070 | ARTIFICIAL LIPID MEMBRANE FORMING METHOD AND ARTIFICIAL LIPID MEMBRANE FORMING APPARATUS - An object of the present invention is to provide a method for easily forming an artificial lipid membrane in a short period of time and an artificial lipid membrane forming apparatus suitable for carrying out such method. | 08-26-2010 |
| 20100216891 | AROMATIC ANTIHYPERTENSIVE AGENT, AND METHOD FOR LOWERING BLOOD PRESSURE IN MAMMALS - The present invention provides an antihypertensive agent having a superior antihypertensive action, and a method for lowering blood pressure in mammals by inhalation of such an antihypertensive agent through the nostril. | 08-26-2010 |
| 20100241150 | SKIN INCISION INSTRUMENT AND METHOD FOR INCISING SKIN WITH THE SAME - Provided are skin incision instrument to efficiently incise minimal portions and a method for incising skin with the skin incision instrument. The skin incision instrument according to the present invention comprises a holder, a needle, a needle drive unit, a skin expander, and a reader, wherein the needle and the skin expander are mounted at an end of the holder, the needle drive unit is mounted in the holder, the needle drive unit is capable of forming an incision portion in a skin caused to contact the end of the holder by moving the needle, the skin expander is capable of expanding skin at both sides of the linear incision portion away from the linear incision portion in a direction to expand the linear incision portion, and the reader determines position of the skin expander by rotating the skin expander around the needle in order to adjust an angle to 45 degrees or more and 90 degrees or less wherein the angle is a smaller angle among angles formed by the representative line connecting both ends of the linear incision portion and the direction to expand skin at both sides of the linear incision portion with the skin expander, and minimal portions are efficiently incised. | 09-23-2010 |
| 20100268259 | SKIN INCISION INSTRUMENT AND METHOD FOR INCISING SKIN WITH THE SAME - Provided are skin incision instrument to efficiently incise minimal portions and a method for incising skin with the skin incision instrument. The skin incision instrument according to the present invention comprises a holder, a needle, a needle drive unit, two or more skin expander sets, and a reader, wherein the skin expander sets comprise a first skin expander and a second skin expander; the first skin expander and the second skin expander are capable of expanding skin at both sides of the linear incision portion away from the linear incision portion and expanding the linear incision portion in a direction to expand the linear incision portion; and, minimal portions are efficiently incised by selecting a single skin expander set from two or more of the skin expander set based on the direction of the linear incision portion, such that an angle is adjusted to 45 degrees or more and 90 degrees or less wherein the angle is formed by the direction of the linear incision portion read by the reader and the direction to expand the skin by the single skin expander set. | 10-21-2010 |
| 20110083793 | METHOD FOR FORMING ARTIFICIAL LIPID MEMBRANE - An object of the present invention is to provide a method for stably forming an artificial lipid membrane while suppressing the leakage and evaporation of an electrolytic solution. | 04-14-2011 |