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Hirao

Ichiro Hirao, Tokyo JP

Patent application numberDescriptionPublished
20110306653STABILIZATION METHOD OF FUNCTIONAL NUCLEIC ACID - This invention is intended to enhance and improve the resistance of a single- or double-stranded nucleic acid fragment comprising a base sequence of a functional nucleic acid to degradation by nucleolytic enzymes in a simple and cost-effective manner. The single- or double-stranded nucleic acid fragment comprises, ligated to at least one end thereof, hairpin-shaped DNA comprising: (A) a nucleic acid region comprising 2 to 5 arbitrary nucleotides; (B) a nucleic acid region comprising a “gna” or “gnna” base sequence, wherein each “n” represents “g”, “t”, “a”, or “c”, a base analogue, or a modified base; and (C) a nucleic acid region comprising a base sequence complementary to the nucleic acid region (A), sequentially from the 5′ end toward the 3′ end.12-15-2011

Koichi Hirao, Shiga JP

Patent application numberDescriptionPublished
20110311430PROCESS FOR PRODUCTION OF PRECURSOR FIBER FOR PREPARING CARBON FIBER HAVING HIGH STRENGTH AND HIGH ELASTIC MODULUS - The present invention provides a process for producing a precursor fiber which can provide a carbon fiber having high strength and high elastic modulus. The process of the present invention comprises a step where an aqueous solution of amphoteric molecule is prepared; a step where carbon nanotube is added to the aqueous solution of the amphoteric molecule so that the carbon nanotube is dispersed therein to prepare a dispersion of carbon nanotube; a step where the carbon nanotube dispersion is mixed with a polyacrylonitrile polymer and rhodanate or zinc chloride to prepare a spinning dope; a step where a coagulated yarn is prepared from the spinning dope by a wet or dry-wet spinning method; and a step where the coagulated yarn is drawn to give a precursor fiber for carbon fiber.12-22-2011
20110311444IMAGING DIAGNOSTIC AGENT AND EXTRACORPOREAL DIAGNOSTIC AGENT FOR INCURABLE NEUROLOGICAL DISEASES - Disclosed are a curcumin derivative or a salt thereof, which contains a fluorine atom, represented by formula (I):12-22-2011

Lauren A. Hirao, Philadelphia, PA US

Patent application numberDescriptionPublished
20090304627SMALLPOX DNA VACCINE AND THE ANTIGENS THEREIN THAT ELICIT AN IMMUNE RESPONSE - The present invention relates to DNA vaccines that are capable of generating a protective immune response in mammals against a pox virus, and comprises at least one DNA plasmid capable of expressing a plurality of VACV MV antigens, and at least one DNA plasmid capable of expressing a plurality of VACV EV antigens. Also, the present invention relates to methods of inducing a protective immune response in a mammal to pox virus, including a neutralizing antibody response, comprising: injecting into tissue of said mammal said DNA vaccine.12-10-2009

Michiko Hirao, Kanagawa JP

Patent application numberDescriptionPublished
20110306653STABILIZATION METHOD OF FUNCTIONAL NUCLEIC ACID - This invention is intended to enhance and improve the resistance of a single- or double-stranded nucleic acid fragment comprising a base sequence of a functional nucleic acid to degradation by nucleolytic enzymes in a simple and cost-effective manner. The single- or double-stranded nucleic acid fragment comprises, ligated to at least one end thereof, hairpin-shaped DNA comprising: (A) a nucleic acid region comprising 2 to 5 arbitrary nucleotides; (B) a nucleic acid region comprising a “gna” or “gnna” base sequence, wherein each “n” represents “g”, “t”, “a”, or “c”, a base analogue, or a modified base; and (C) a nucleic acid region comprising a base sequence complementary to the nucleic acid region (A), sequentially from the 5′ end toward the 3′ end.12-15-2011

Takashi Hirao, Itami-Shi JP

Patent application numberDescriptionPublished
20120034474JOINED PRODUCT - A joined product according to the present invention is a joined product including a cemented carbide sintered compact serving as a first material to be joined and a cBN sintered compact or a diamond sintered compact serving as a second material to be joined. The first material to be joined and the second material to be joined are joined by a joining material that forms a liquid phase at a temperature exceeding 800° C. and lower than 1000° C. and that is placed between the first material to be joined and the second material to be joined. The first material to be joined and the second material to be joined are joined by resistance heating and pressing at a pressure of 0.1 to 200 MPa.02-09-2012

Takayuki Hirao, Orangeburg, NY US

Patent application numberDescriptionPublished
20110209896FEP PELLET - An FEP pellet having a volatile content of 0.2% by weight or less. The FEP pellet satisfies the following requirements (i) and (ii) when used to form a insulating material coating a core wire by extrusion coating at a coating speed of 2,800 ft/min.: (i) an adhesive strength between the insulating material and said core wire of 0.8 kg or more; and (ii) an average number of cone-breaks in the insulating material of one or less per 50,000 feet of the coated core wire.09-01-2011

Wagner Yukio Hirao, Troy, MI US

Patent application numberDescriptionPublished
20080236908ELECTRIC POWERTRAIN SYSTEM WITH PLANETARY DRIVE - An electric drive unit for a vehicle wheel includes an electric motor that powers a planetary drive having a first stage gear set and a second stage gear set. Each of the first and second stage gear sets includes a sun gear that is driven by a motor output shaft. Each of the first and second stage gear sets also includes a plurality of planet gears that are in meshing engagement with a respective one of the sun gears. The first and second stage gear sets share a common ring gear. A planet carrier of the second stage gear set provides driving output to a wheel shaft that drives the vehicle wheel.10-02-2008
20120021863HYPOID GEAR SET FOR DRIVE AXLE - A hypoid gear set for a vehicle drivetrain includes a pinion gear in meshing engagement with a ring gear. The hypoid gear set has a negative pinion offset. The hypoid pinion and ring gears provide a predetermined gear ratio that can be varied up to a fifty percent faster ratio within a single carrier packaging envelope defined by a maximum ring gear diameter.01-26-2012

Yoshinori Hirao, Kanagawa JP

Patent application numberDescriptionPublished
20120058511MUTANT MICROORGANISM AND METHOD FOR PRODUCING PEPTIDE USING THE SAME - The present invention provides a method for producing the peptides comprising: 03-08-2012