Patent application number | Description | Published |
20100015244 | Nano/Macroporous Bioactive Glasses Made by Melt-Quench Methods - The methods and materials described herein provide novel and simple procedures for the preparation of nano/macroporous glasses, in which the pore structure is characterized by interconnected pores of, e.g. both hundreds of micrometers and several to tens of nanometers in size. Such materials may be used for enhanced bone regeneration, bioscaffolds, drug delivery devices, and filtration media, among other uses. For example, silica-based bone tissue scaffolds are made with a controlled nano/macroporosity, which enhances bone regeneration performance. Also provided herein are new biocompatible CaO—Na | 01-21-2010 |
20100272826 | NANO/MACROPOROUS BONE TISSUE SCAFFOLDS FOR REGENERATIVE MEDICINE - A biocompatible inorganic porous material having a three-dimensional coexistent network of interconnected macro-pores and nanopores produced by the steps of mixing an organic water-soluble polymer (e.g., polyethylene oxide or a block copolymer of ethylene oxide and propylene oxide), an alkoxysilane, and an inorganic water-soluble calcium salt in an aqueous acid solution, such that a sol-gel process of hydrolysis and polycondensation is initiated and thereby producing a gel; drying the gel to remove solvent by evaporation; and heating the gel to remove the polymer by thermal decomposition, thereby forming an inorganic porous material, which may be suitable for use as a bone tissue scaffold. | 10-28-2010 |
20110057154 | CONDUCTIVE DOPED METAL-GLASS COMPOSITIONS AND METHODS - Provided herein are conductive glass-metal compositions, as well as methods of making and using such compositions. In one example, the compositions include gold (Au) doped lithium-borate glasses shown to exhibit a transition from ionic to electronic conduction within the same sample. This is achieved via appropriate heat treatment, and particularly by heat treatment after annealing, wherein the post-annealing heat treatment is performed at temperatures below the glass transition temperature (T | 03-10-2011 |
20120094122 | FABRICATION OF NANOPOROUS GLASS FIBER FOR FLEXIBLE BIOSCAFFOLDS AND OTHER PRODUCTS - Provided herein are novel nanoporous glass fibers, and methods of preparing and using such fibers. In some embodiments, articles are made from particular glass starting materials, such as soda-lime phosphosilicate glass fabricated by melt-quench methods. The articles include nanoporous fibers that can be used alone, or sewn, woven, bundled, and otherwise incorporated to form nanoporous articles, including bioactive articles. | 04-19-2012 |
20120189844 | METHODS TO FABRICATE NANO-MACRO POROUS GLASS USING A WATER SOLUBLE PORE FORMER - Provided herein are methods for preparing nano-macroporous glass articles, such as bioscaffolds, from starting materials such as phosphosilicate glasses made by melt-quench methods, mixed with a soluble pore former such as a sugar, followed by steps of dissolving, heating, and leaching to yield a glass composition having a highly interconnected system of both macropores and large scale nanoporosity. | 07-26-2012 |
20130256627 | Sensors Incorporating Freestanding Carbon NanoStructures - Sensors for detecting IR radiation, UV radiation, X-Rays, light, gas, and chemicals. The sensors herein incorporate freestanding carbon nanostructures, such as single-walled carbon nanotubes (“SWCNT”), atomically thin carbon sheets having a thickness of about between 1 atom and about 5 atoms (“graphene”), and combinations thereof. The freestanding carbon nanostructures are suspended above a substrate by a plurality of conductors, each conductor electrically connected to the carbon nanostructure. In one method of manufacture, a resonance chamber is formed under the carbon nanostructure by etching of the substrate, yielding a sensor wherein the resonance chamber is bounded by at least the substrate and the carbon nanostructure. | 10-03-2013 |
20140075993 | Fabrication of Porous Glass Bioscaffolds By Sol-Gel and Polymer Sponge Methods - Provided herein are biocompatible scaffolds and methods of preparing such bioscaffolds. The methods provide a superior high surface area, interconnected nanomacroporous bioactive glass scaffold, by combining a sol-gel process and polymer sponge replication methods. The formation of a uniformly nanoporous and interconnected macroporous bioscaffold is demonstrated using a starting material comprising a 70 mol % SiO2—30 mol % CaO glass composition as an example. The bioscaffold includes a series of open, interconnected macropores with size from 300 to 600 μm, as desired for tissue ingrowth and vascularization. At the same time, coexisting nanopores provide high-specific surface area (>150 m2/g), which is needed for enhancing the structure's degradation rate. These bioscaffolds hold promise for applications in hard tissue engineering. | 03-20-2014 |
20150118321 | BIOACTIVE GLASS PREPARATION AND USE - A process of preparing a glass comprising: (a) heating a mixture of precursor chemicals to a melt temperature to form a melt, the melt being characterized in that quenching the melt at or above a threshold temperature results in a spinodal phase seperation, and quenching the melt below the threshold temperature results in a droplet phase seperation; and (b) quenching the melt at or above the threshold temperature in a preheated mold to form the glass composition having the spinodal phase seperation. | 04-30-2015 |