Hiles
Andrew George Hiles, London GB
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20100286454 | PROCESS FOR THE CO-PRODUCTION OF FATTY ALCOHOLS SHOWING DIFFERENT CARBON CHAIN LENGTHS - A process for the co-production of a stream of a fatty alcohol having first carbon chain lengths and a stream of a fatty alcohol having a second carbon chain lengths, said second carbon chain lengths being longer than said first carbon chain lengths, said process comprising the steps of: (a) supplying a stream comprising lower alkyl esters of fatty acids having chain lengths comprising the first and second chain lengths to a first vaporisation zone and contacting said stream with an amount of hydrogen which is sufficient to vaporise the lower alkyl esters of the fatty acids having the first carbon chain lengths into the hydrogen; (b) supplying the hydrogen and the vaporised lower alkyl esters of fatty acids having the first carbon chain lengths to a first reaction zone comprising catalyst and operating under reaction conditions to allow hydrogenation to the desired alcohol having first carbon chain lengths; (c) recovering from the first reaction zone an alcohol product stream having first carbon chain lengths and hydrogen; (d) separating the stream of fatty alcohol having the first carbon chain lengths from hydrogen; (e) supplying the unvaporised lower alkyl esters of the fatty acids having second carbon chain lengths remaining from step (a) to a second vaporisation zone; (f) contacting the unvaporised lower alkyl esters having second carbon chain lengths in the second vaporisation zone with hydrogen recovered in step (d) and an additional amount of hydrogen such that the total amount of hydrogen is sufficient to vaporise the lower alkyl esters having fatty acids of the second carbon chain lengths into the hydrogen; (g) supplying the hydrogen and the vaporised lower alkyl esters of fatty acids having second carbon chain lengths to a second reaction zone comprising catalyst and operating under reaction conditions to allow hydrogenation to the desired alcohol having second carbon chain lengths; and (h) recovering from the second reaction zone an alcohol product stream having second carbon chain lengths and hydrogen. | 11-11-2010 |
20120016163 | PROCESS FOR THE CO-PRODUCTION OF A STREAM OF A FATTY ALCOHOL HAVING A FIRST CARBON CHAIN LENGTH AND A STREAM OF A FATTY ALCOHOL HAVING A SECOND CARBON LENGTH - A process for the co-production of a stream of a fatty alcohol having first carbon chain lengths and a stream of a fatty alcohol having a second carbon chain lengths, said second carbon chain lengths being longer than said first carbon chain lengths, said process comprising the steps of: (a) supplying a stream comprising lower alkyl esters of fatty acids having chain lengths comprising the first and second chain lengths to a first vaporisation zone and contacting said stream with an amount of hydrogen recycled from step (i) which is sufficient to vaporise the lower alkyl esters of the fatty acids having the first carbon chain lengths into the hydrogen; (b) supplying the hydrogen and the vaporised lower alkyl esters of fatty acids having the first carbon chain lengths to a first reaction zone comprising catalyst and operating under reaction conditions to allow hydrogenation to the desired alcohol having first carbon chain lengths; (c) recovering from the first reaction zone an alcohol product stream having first carbon chain lengths and the hydrogen; (d) supplying the unvaporised lower alkyl esters of the fatty acids having second carbon chain lengths remaining from step (a) to a second vaporisation zone; (e) contacting the unvaporised lower alkyl esters having second carbon chain lengths in the second vaporisation zone with an amount of hydrogen sufficient to vaporise the lower alkyl esters having fatty acids of the second carbon chain lengths into the hydrogen; (f) supplying the hydrogen and the vaporised lower alkyl esters of fatty acids having second carbon chain lengths to a second reaction zone comprising catalyst and operating under reaction conditions to allow hydrogenation to the desired alcohol having second carbon chain lengths; (g) recovering from the second reaction zone an alcohol product stream having second carbon chain lengths and hydrogen; (h) separating the stream of fatty acid alcohol having the second carbon chain length from hydrogen; and (i) recycling a portion of the hydrogen recovered in step (h) to the first vaporisation zone and a portion to the second vapourisation zone. | 01-19-2012 |
Calvin L. Hiles, Ligonier, PA US
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20150352640 | TOOL HOLDER HAVING IMPROVED INTERNAL COOLANT DELIVERY - A tool holder for carrying a cutting insert wherein the cutting insert is useful for the removal of material during a material removal operation. The tool holder includes a tool holder body. The tool holder body includes a pocket adapted to carry the cutting insert, a coolant inlet in communication with a pressurized source of coolant, a coolant chamber having a central region, an upstream coolant passage having a central longitudinal upstream coolant passage axis, and a downstream coolant passage having a central longitudinal downstream coolant passage axis. The upstream coolant passage opens into the coolant chamber. The upstream coolant passage has an orientation relative to the coolant chamber so that the central longitudinal upstream coolant passage axis is offset from the central region of the coolant chamber whereby coolant flows into the coolant chamber in a tangential fashion. | 12-10-2015 |
Ian Hiles, London GB
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20080234190 | Glial mitogenic factors, their preparation and use - Disclosed is the characterization and purification of DNA encoding a numerous polypeptides useful for the stimulation of glial cell (particularly, Schwann cell) mitogenesis and treating glial cell tumors. Also disclosed are DNA sequences encoding novel polypeptides which may have use in stimulating glial cell mitogenesis and treating glial cell tumors. Methods for the synthesis, purification and testing of both known and novel polypeptides for their use as both therapeutic and diagnostic aids in the treatment of diseases involving glial cells are also provided. Methods are also provided for the use of these polypeptides for the preparation of antibody probes useful for both diagnostic and therapeutic use in diseases involving glial cells. | 09-25-2008 |
20090246867 | Glial mitogenic factors, their preparation and use - Disclosed is the characterization and purification of DNA encoding a numerous polypeptides useful for the stimulation of glial cell (particularly, Schwann cell) mitogenesis and treating glial cell tumors. Also disclosed are DNA sequences encoding novel polypeptides which may have use in stimulating glial cell mitogenesis and treating glial cell tumors. Methods for the synthesis, purification and testing of both known and novel polypeptides for their use as both therapeutic and diagnostic aids in the treatment of diseases involving glial cells are also provided. Methods are also provided for the use of these polypeptides for the preparation of antibody probes useful for both diagnostic and therapeutic use in diseases involving glial cells. | 10-01-2009 |
John Hiles, Cheshire GB
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20120095409 | SEAL MEMBER - A seal member is configured to seal a chamber of a drug delivery device which is suitable to contain a drug, wherein the seal member comprises a diaphragm. | 04-19-2012 |
20120095414 | DRUG DELIVERY DEVICE - Drug delivery device, comprising a body unit having a first opening and a second opening, a plunger arranged such that its distal end is positioned inside the body unit, wherein the plunger is moveable in the distal direction with respect to the body unit, a needle assembly, with a proximal end and a distal end comprising a needle, wherein the proximal end of the needle assembly and the distal end of the plunger are configured such that they can get into an adhesion connection. | 04-19-2012 |
20120095438 | MEDICATION DELIVERY DEVICE WITH FOLDABLE FINGER PAD - A medication delivery device is configured to deliver medication when a button element is moved, the medication delivery device having a folding finger pad. | 04-19-2012 |
20120116320 | Drug Delivery Device - Drug delivery device, comprising a body unit having a first opening and a second opening, a plunger arranged such that its distal end is positioned inside the body unit, wherein the plunger is moveable in the distal direction with respect to the body unit, a needle assembly, with a proximal end and a distal end comprising a needle, wherein the proximal end of the needle assembly and the distal end of the plunger are configured such that they can get into a vacuum connection. | 05-10-2012 |
20120123351 | Needle Assembly - A needle assembly ( | 05-17-2012 |
20120136318 | Drug Delivery Device with Retractable Needle - Drug delivery device, comprising a needle, which a distal end and a proximal end comprises an inner surface forming a channel, an outer surface, a first salient located on the outer surface. | 05-31-2012 |
20140094752 | Guide Device for Intraocular Injection - Described is a guide device for intraocular injection comprising a base plate having an inner surface and an outer surface, a handle formed on the outer surface, and a hole formed in the base plate and extending through the inner and outer surfaces. The inner surface is adapted to contact an eye ball. | 04-03-2014 |
John Hiles, South Wirral GB
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20130023832 | Drug Delivery Devices and Method of Assembly - A drug delivery device for dispensing of a dose of a medicinal product, comprising a holder ( | 01-24-2013 |
20130150786 | CODED KEYING INSERT FOR A MEDICAMENT CARTRIDGE - A keying insert for use with a cartridge assembly containing a fluid. The insert comprises a main body defining a bore that extends from a proximal end to a distal end of the main body and allows the fluid to dispense from the distal end of the cartridge through a septum. The main body includes a septum for sealing the fluid within the cartridge and a coding feature that is keyed to a cartridge holder or other dispense interface. | 06-13-2013 |
20140221924 | NEEDLE SAFETY DEVICE - Described is a needle safety device comprising a needle hub, a needle coupled to the needle hub and having a distal tip, a sleeve coupled to the needle hub, a needle shield telescopically coupled to the sleeve; and a needle disabling mechanism coupled to the needle. In a first axial position, the needle shield covers the distal tip of the needle and the needle disabling mechanism is in a first angular position. In a retracted position, the needle shield is retracted relative to the needle exposing the distal tip of the needle. In a second axial position, the needle shield is distal of the first axial position and the needle disabling mechanism is in a second angular position bending the needle. | 08-07-2014 |
John Hiles, South Wirral DE
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20130131605 | DRIVE MECHANISM FOR A DRUG DELIVERY DEVICE AND DRUG DELIVERY DEVICE - A drive member and a rotation member are rotatable with respect to a housing. The drive member comprises drive fingers, which are resilient or resiliently mounted. A slider is disposed at the drive member and is axially movable between a first position, in which the slider keeps the drive fingers constrained, and a second position, in which the drive fingers are released. A unidirectional rotational clutch engages the drive member with the rotation member. The clutch is formed by the drive fingers when the slider is in the first position. The drive member and the rotation member are disengaged when the slider is in the second position. The slider is in the first position when a unit is attached to the housing, and in the second position when the unit is removed. | 05-23-2013 |
John Hiles, South Wirral Cheshire GB
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20140352480 | Collapsible Steering Column Assembly - A collapsible steering column assembly for a vehicle comprises a shroud which surrounds a steering column shaft, a mounting bracket secured to or integral with a fixed part of the vehicle, a support bracket secured to the mounting bracket through one or more frangible connectors, a clamp mechanism which releasably secures the shroud to the support bracket, and a blocking part which is fixed in position relative to the mounting and at least in an unclamped condition of the clamp mechanism provides an additional force path between the clamp mechanism and the mounting bracket that does not pass through the support bracket. In the event that an axial load is applied to the steering assembly when the clamp mechanism is unlocked and has reached the end of its allowable travel at least some of the load is carried through the clamp mechanism and the blocking part to the mounting bracket along the additional force path. | 12-04-2014 |
Kevin Hiles, Princeton Junction, NJ US
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20120199730 | High Voltage Insulating Sleeve For Nuclear Well Logging - A well logging instrument includes an instrument housing to traverse a wellbore penetrating subsurface formations. An electrically operated energy source that emits ionizing radiation is disposed inside the housing. An insulating sleeve is disposed between the energy source and an interior wall of the housing. The insulating sleeve comprises a thin dielectric film arranged in a plurality of tightly fitting layers of dielectric material disposed adjacent to each other and successively. A thickness of each layer and a number of layers is selected to provide a dielectric strength sufficient to electrically insulate the energy source from the housing and to provide a selected resistance to dielectric failure resulting from the ionizing radiation. | 08-09-2012 |
Kevin L. Hiles, Pittstown, NJ US
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20150194871 | Method And Apparatus For Regulating High Voltage - A method for regulating output of a high voltage generator includes monitoring a voltage output of the generator and comparing it to a voltage setpoint to generate an error signal. A load on the generator is monitored to generate a load signal. The load signal is conducted to a feedforward signal generator. The feedforward signal generator is configured to produce a feedforward signal corresponding to the load and to at least one parameter related to an output impedance of the high voltage generator. The error signal is conducted to a high voltage regulation loop. The control loop output and the feedforward signal generator output are coupled to a driver for the high voltage generator. | 07-09-2015 |
Paul E. Hiles, Tomball, TX US
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20080266767 | Electronic device having interchangeable display member - A portable electronic device comprises a housing configured to releasably secure thereto one of a plurality of interchangeable display members, at least two of the plurality of display members comprising different types of display members. | 10-30-2008 |
Sarah Lindsay Hiles, Warton GB
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20130080344 | ESTIMATING PROCESS AND SYSTEM - Processes and apparatus are disclosed for determining how mature an estimate is by assessing the basis of an estimate against a scale of criteria or categories of plural relative values of maturity of estimate. Confidence levels derived for two different estimating processes for a same estimate, can be reconciled; and an estimating process can be controlled by systematically reviewing the readiness of a planned estimating process by reviewing the basis of the estimate by assessment of determined maturity level values in a document register. An estimating process can also be controlled by controlling the iterative performance of different estimate assessment and/or preparation processes dependent upon a maturity of a basis of the estimate. | 03-28-2013 |
Van Hiles, Greenwell Springs, LA US
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20140349789 | PRE-FORMED LACROSSE POCKET - An aspect of the present invention relates to a lacrosse pocket comprising a preformed composite material including an outer edge for attaching to a lacrosse head and an interior channel within the outer edge having a desired concave shape and depth, wherein the interior channel, for receiving and releasing a lacrosse ball, permanently maintains the desired concave shape and depth. | 11-27-2014 |