Patent application number | Description | Published |
20120045433 | COMBINATION THERAPY - The present invention relates to a combination therapy of propane-1-sulfonic acid {3-[5-(4-chlorophenyl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluoro-phenyl}-amide, or a pharmaceutically acceptable salt thereof, and an topoisomerase inhibitor for treating a patient suffering from a proliferative disorder, in particular a solid tumor, for example, colorectal cancer, melanoma, and thyroid cancer. In particular, the present invention relates to such a therapy wherein the topoisomerase inhibitor is irinotecan, or a pharmaceutically acceptable salt thereof, and the disorder is colorectal cancer involving a tumor comprising b-Raf having the V600E mutation. | 02-23-2012 |
20120045434 | COMBINATION THERAPY - The present invention relates to a combination therapy of propane-1-sulfonic acid {3-[5-(4-chloro-phenyl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluoro-phenyl}-amide, or a pharmaceutically acceptable salt thereof, and an EGFR inhibitor for treating a patient suffering from a proliferative disorder, in particular a solid tumor, for example, colorectal cancer, melanoma, and thyroid cancer. | 02-23-2012 |
20120148533 | COMBINATION THERAPY - The present invention relates to a combination therapy of propane-1-sulfonic acid{3-[5-(4-chloro-phenyl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl-2,4-difluoro-phenyl]-amide}, or a pharmaceutically acceptable salt thereof, and an interferon for treating a patient suffering from a proliferative disorder, in particular a solid tumor, for example, colorectal cancer, melanoma, and thyroid cancer. In particular, the present invention relates to such a therapy wherein the interferon is peginterferon alfa-2a and the disorder is melanoma containing the V600E b-Raf mutation. | 06-14-2012 |
20130245039 | COMBINATION THERAPY FOR PROLIFERATIVE DISORDERS - Treatment of proliferative diseases with a combination of a b-Raf inhibitor and MDM2 inhibitor. | 09-19-2013 |
20130245089 | METHOD FOR ADMINISTRATION - There is provided a new dosage regimen for Compound A which maximizes anti-tumor activity while maintaining acceptable toxicity levels. | 09-19-2013 |
20140200255 | METHOD FOR ADMINISTRATION - There is provided a new dosage regimen for Compound A which maximizes anti-tumor activity while maintaining acceptable toxicity levels. | 07-17-2014 |
Patent application number | Description | Published |
20100190047 | VARIABLE VOLUME CONTAINMENT FOR ENERGY STORAGE DEVICES - A stacked energy storage device (ESD) has at least two cell segments arranged in a stack. Each cell segment may have a first electrode unit having a first active material electrode, a second electrode unit having a second active material electrode, and an electrolyte layer between the active material electrodes. Variable volume containment may be used to control the inter-electrode spacing within each cell segment. In some embodiments, one or more dynamic flexible gaskets may be included in each cell segment to seal the electrolyte within the cell segment and to deform in preferred directions. In some embodiments, hard stops may set the inter-electrode spacing of the ESD. | 07-29-2010 |
20100203384 | ELECTRODE FOLDS FOR ENERGY STORAGE DEVICES - A stacked energy storage device (ESD) has at least two conductive substrates arranged in a stack. Each cell segment may have a first electrode unit having a first active material electrode, a second electrode unit having a second active material electrode, and an electrolyte layer between the active material electrodes. Each active material electrode may have a plurality of folded sections and planar sections to increase the ESD capacity, for example, by increasing number of interfaces within each cell segment. | 08-12-2010 |
20100310923 | BI-POLAR RECHARGEABLE ELECTROCHEMICAL BATTERY - A bi-polar battery has a positive electrode unit, a negative electrode unit, at least one bi-polar electrode unit stacked therebetween, an electrolyte layer separating each adjacent electrode unit, and a gasket positioned about each electrolyte layer for creating a seal about the electrolyte layer in conjunction with the electrode units adjacent thereto. The bi-polar battery also includes a wrapper for maintaining the seals created by the gaskets. | 12-09-2010 |
Patent application number | Description | Published |
20090307126 | Multi-Currency Marketplace - A computerized method and system buying and selling in a marketplace denominated in multiple currencies. A best bid or best offer can be determined according to pecuniary advantage based upon a selected currency. An amount required to become a best bid or best offer within a set of defined currencies is also included. Some embodiments include a network of computers permitting access to a multi-currency marketplace. Prices in the multi-currency marketplace can be ranked according to a particular currency selected by a market participant. | 12-10-2009 |
20120150568 | Automated Online Sales Risk Management - The present invention contemplates a risk management system for facilitating an e-commerce transaction wherein the participants to the transaction engage in commerce using different currencies. An automated sales risk management system facilitates a transaction by providing a price of a transaction which incorporates aggregated costs related to the transaction into a price made available to the participants. A currency risk management system can receive an amount relating to a deliverable involved in a transaction and determines an aggregated cost of the transaction. Aggregated cost can include a cost of credit, a cost for exchange of currency, a cost of insurance, processing fees, or other associated costs. Insurance can be monitored and a determination can be made regarding whether a participant has adequate insurance to cover a proposed transaction. The present invention also provides for risk associated with online transactions to be categorized and transferred. | 06-14-2012 |
20120197817 | Basket Option Hedging Method - A method and system for hedging a correlation risk associated with a basket option that includes a plurality of securities that includes the step of selecting at least two of the plurality of securities and, in the next step, forming a best-of option for the at least two of the plurality of securities. Finally, the best-of option is combined with the basket option to hedge the correlation risk associated with the basket option. | 08-02-2012 |
20140344133 | Basket Option Hedging Method - A method and system for hedging a correlation risk associated with a basket option that includes a plurality of securities that includes the step of selecting at least two of the plurality of securities and, in the next step, forming a best-of option for the at least two of the plurality of securities. Finally, the best-of option is combined with the basket option to hedge the correlation risk associated with the basket option. | 11-20-2014 |
Patent application number | Description | Published |
20090023061 | Stacked constructions for electrochemical batteries - A stacked battery has at least two cell segments arranged in a stack. Each cell segment may have a first electrode unit having a first active material electrode, a second electrode unit having a second active material electrode, and an electrolyte layer between the active material electrodes. One or more gaskets may be included in each cell segment to seal the electrolyte within the cell segment. | 01-22-2009 |
20090142655 | DISH SHAPED AND PRESSURE EQUALIZING ELECTRODES FOR ELECTROCHEMICAL BATTERIES - A stacked battery has at least two cell segments arranged in a stack. Each cell segment may have a first electrode unit having a first active material electrode, a second electrode unit having a second active material electrode, and an electrolyte layer between the active material electrodes. One or more gaskets may be included in each cell segment to seal the electrolyte within the cell segment. The electrode units may be “dish shaped” and may contain a pressure equalization valve to reduce electrode unit deflection and improve pressure equalization between cell segments. The pressure equalization valve may allow a gas to diffuse through adjacent cell segments and may substantially prevent electrolyte from diffusing through. | 06-04-2009 |
20100190047 | VARIABLE VOLUME CONTAINMENT FOR ENERGY STORAGE DEVICES - A stacked energy storage device (ESD) has at least two cell segments arranged in a stack. Each cell segment may have a first electrode unit having a first active material electrode, a second electrode unit having a second active material electrode, and an electrolyte layer between the active material electrodes. Variable volume containment may be used to control the inter-electrode spacing within each cell segment. In some embodiments, one or more dynamic flexible gaskets may be included in each cell segment to seal the electrolyte within the cell segment and to deform in preferred directions. In some embodiments, hard stops may set the inter-electrode spacing of the ESD. | 07-29-2010 |
20100203384 | ELECTRODE FOLDS FOR ENERGY STORAGE DEVICES - A stacked energy storage device (ESD) has at least two conductive substrates arranged in a stack. Each cell segment may have a first electrode unit having a first active material electrode, a second electrode unit having a second active material electrode, and an electrolyte layer between the active material electrodes. Each active material electrode may have a plurality of folded sections and planar sections to increase the ESD capacity, for example, by increasing number of interfaces within each cell segment. | 08-12-2010 |
20100310923 | BI-POLAR RECHARGEABLE ELECTROCHEMICAL BATTERY - A bi-polar battery has a positive electrode unit, a negative electrode unit, at least one bi-polar electrode unit stacked therebetween, an electrolyte layer separating each adjacent electrode unit, and a gasket positioned about each electrolyte layer for creating a seal about the electrolyte layer in conjunction with the electrode units adjacent thereto. The bi-polar battery also includes a wrapper for maintaining the seals created by the gaskets. | 12-09-2010 |
20130095366 | STACKED CONSTRUCTIONS FOR ELECTROCHEMICAL BATTERIES - A stacked battery has at least two cell segments arranged in a stack. Each cell segment may have a first electrode unit having a first active material electrode, a second electrode unit having a second active material electrode, and an electrolyte layer between the active material electrodes. One or more gaskets may be included in each cell segment to seal the electrolyte within the cell segment. | 04-18-2013 |
20130101882 | STACKED CONSTRUCTIONS FOR ELECTROCHEMICAL BATTERIES - A stacked battery has at least two cell segments arranged in a stack. Each cell segment may have a first electrode unit having a first active material electrode, a second electrode unit having a second active material electrode, and an electrolyte layer between the active material electrodes. One or more gaskets may be included in each cell segment to seal the electrolyte within the cell segment. | 04-25-2013 |
20130101890 | STACKED CONSTRUCTIONS FOR ELECTROCHEMICAL BATTERIES - A stacked battery has at least two cell segments arranged in a stack. Each cell segment may have a first electrode unit having a first active material electrode, a second electrode unit having a second active material electrode, and an electrolyte layer between the active material electrodes. One or more gaskets may be included in each cell segment to seal the electrolyte within the cell segment. | 04-25-2013 |
20140370374 | VARIABLE VOLUME CONTAINMENT FOR ENERGY STORAGE DEVICES - A stacked energy storage device (ESD) has at least two cell segments arranged in a stack. Each cell segment may have a first electrode unit having a first active material electrode, a second electrode unit having a second active material electrode, and an electrolyte layer between the active material electrodes. Variable volume containment may be used to control the inter-electrode spacing within each cell segment. In some embodiments, one or more dynamic flexible gaskets may be included in each cell segment to seal the electrolyte within the cell segment and to deform in preferred directions. In some embodiments, hard stops may set the inter-electrode spacing of the ESD. | 12-18-2014 |
Patent application number | Description | Published |
20100149229 | CONTROLLING DIGITAL PRINTING - A method and system for digital printing with plural marking engines in which a controller determines which of the marking engines has first completed its initialization/warm-up cycle and begins printing on that marking engine. As additional marking engines complete their initialization/warm-up cycle, additional concurrent printing is commenced on them. | 06-17-2010 |
20100179783 | CORRECTING TILT-INDUCED CYCLIC VARIATIONS IN SIGNALS FROM RADIALLY ARRAYED SPECTROPHOTOMETER SENSORS - A correction algorithm may be applied for correcting misalignment of a radially-aligned array of sensors. Due to the tilt, signals from sensors that are further away from the media, may become slightly attenuated, while signals from sensors that are closer to the media are slightly increased. The error appears periodic and largely sinusoidal in nature around the array given the circular nature of the array of sensor elements. The algorithm determines the magnitude and phase of a sinusoidal function that best fits the wavelength data. In one embodiment, a discrete Fourier transform may be performed at the ‘frequency’ equivalent to one period around the array to determine the magnitude and phase estimate thereof. Then, a sinusoidal correction function may be generated using the magnitude and the phase in order to correct the reflectance data. | 07-15-2010 |
20100209161 | CONTROLLING SHEET REGISTRATION IN A DIGITAL PRINTING SYSTEM - A digital printing system employing tandem marking engines for duplex printing utilizing a variable dwell time in the output sheet inverter of the first marking engine to provide correct positioning of the leading edge of the inverted sheet for arrival at the entrance of the second marking to avoid the seam in the photoreceptor. | 08-19-2010 |
20120106992 | METHOD TO AUTOMATE A TRANSFER ASSIST BLADE DEVICE TIMING ADJUSTMENT - When calibrating a transfer assist blade (TAB) in a printer, toner patches are formed on a photoreceptor belt in the printer at locations between sheets of paper. The TAB is partially deployed between paper sheets to pick up toner, and then deployed normally or with a delay to mark the back sides of the sheets. A processor evaluates distances between TAB touchdown and liftoff points and leading and trailing edges of the sheets, and calibrates the TAB to optimize the TAB timing. Additionally, test prints can be generated, each having slightly varied TAB calibration settings that are stored in a non-volatile memory (NVM) table. A user enters an identification number for a test print with the best calibration settings. The processor looks up calibration settings corresponding to the entered identification number and moves NVM settings from the table into operational locations in the system NVM to calibrate the printer. | 05-03-2012 |
Patent application number | Description | Published |
20090223411 | ORGANOSILANE-NONIONIC-WATER STABLE QUATERNARY AMMONIUM COMPOSITIONS AND METHODS - Methods of applications of organosilanes optionally having a nonhydrolyzable organic group, but having one or more hydrolyzable groups, with a polyol containing at least three hydroxy groups, where any two of the hydroxy groups are separated by at least three intervening atoms by aerosolization of droplets between 0.5-8 microns are disclosed and an improved formulation comprising adding a nonionic wetting agent are disclosed. An improved aerosolization application technique and the improved formulation provide for smaller droplet size and better coverage of substrates to which the organosilanes are applied. The improved formulation has increased affinity, reduces surface tension and therefore can covalently bond more quickly. A method of treating a substrate, and the treated substrate so formed, by contacting the substrate with the improved formulation for a period of time sufficient for treatment of the substrate are disclosed. | 09-10-2009 |
20100167613 | Organosilane-Nonionic Water Stable Quaternary Ammonium Compositions and Methods - Methods of applications of organosilanes optionally having a nonhydrolyzable organic group, but having one or more hydrolyzable groups, with a polyol containing at least three hydroxy groups, where any two of the hydroxy groups are separated by at least three intervening atoms by aerosolization of droplets between 0.5-8 microns are disclosed and an improved formulation comprising adding a nonionic wetting agent are disclosed. An improved aerosolization application technique and the improved formulation provide for smaller droplet size and better coverage of substrates to which the organosilanes are applied. The improved formulation has increased affinity, reduces surface tension and therefore can covalently bond more quickly. A method of treating a substrate, and the treated substrate so formed, by contacting the substrate with the improved formulation for a period of time sufficient for treatment of the substrate are disclosed. | 07-01-2010 |