Hidalgo, US
Alfredo De Jesús Hidalgo, Cincinnati, OH US
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20110094979 | Product Display System for Disposable Absorbent Article Containers Having Enhanced Visibility and Recognition - A product display system for disposable absorbent article containers is provided. The product display system includes a first stacked product array including a first set of individual disposable absorbent article containers and a second stacked product array including a second set of individual disposable absorbent article containers. Each individual disposable absorbent article container contains a first and second visible graphic such that when the individual containers are stacked appropriately the combination of visible graphics forms a continuous larger visible graphic. The set of stacked product arrays maintains the continuous larger visible graphic, even when some individual containers from the product display are removed or missing. A method for enhancing the visibility and recognition of a product display system is also provided. | 04-28-2011 |
Alfredo De Jesús Hidalgo, Cincinnati, OH US
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20110094979 | Product Display System for Disposable Absorbent Article Containers Having Enhanced Visibility and Recognition - A product display system for disposable absorbent article containers is provided. The product display system includes a first stacked product array including a first set of individual disposable absorbent article containers and a second stacked product array including a second set of individual disposable absorbent article containers. Each individual disposable absorbent article container contains a first and second visible graphic such that when the individual containers are stacked appropriately the combination of visible graphics forms a continuous larger visible graphic. The set of stacked product arrays maintains the continuous larger visible graphic, even when some individual containers from the product display are removed or missing. A method for enhancing the visibility and recognition of a product display system is also provided. | 04-28-2011 |
August Hidalgo, San Francisco, CA US
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20090057548 | Electron multiplier having electron filtering - A system for detecting ions is disclosed. The system includes a detector having a plurality of dynodes arranged in an electron cascading configuration, and a power supply circuit electrically coupled to the plurality of dynodes. The plurality of dynodes include a first dynode and a second dynode. The power supply circuit is arranged to selectively adjust a potential difference between the first and second dynodes between a detection mode and a blanking mode. A method of detecting ions is also disclosed. | 03-05-2009 |
20110024620 | Dithered Multi-Pulsing Time-of-Flight Mass Spectrometer - A detection signal generated in response to incident ions accelerated at temporally-irregular intervals having an average repetition rate greater than a reference repetition rate represents detection events each having an event time and an intensity. For each detection event, respective allowed TOFs between the event time and the transient times are calculated. Using respective initial probabilities, initial apportionments of the intensity of each detection event among the allowed TOFs linked thereto are determined. For each allowed TOF, the intensity apportionments thereto are accumulated to generate an intensity accumulation linked thereto. For each detection event, respective revised probabilities are iteratively determined using the intensity accumulations linked to the allowed TOFs linked thereto, and the respective intensity is iteratively reapportioned among the allowed TOFs linked thereto using the revised probabilities to transform the detection signal to a time-of-flight spectrum. | 02-03-2011 |
August Hidalgo, Loveland, CO US
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20090020697 | Enhanced Resolution Mass Spectrometer and Mass Spectrometry Method - A mass spectrum is generated by a process in which, from a mass scan signal comprising original samples defining a peak, a subset of the original samples defining the peak is selected. One or more synthesized samples are synthesized from the subset of the original samples. The one or more synthesized samples provide a temporal resolution greater than the temporal resolution of the original samples. The one or more synthesized samples are summed with respective temporally-aligned accumulated samples to produce the mass spectrum. The accumulated samples are obtained from mass scan signals generated during respective previously-performed mass scan operations. | 01-22-2009 |
20110210240 | Enhanced Resolution Mass Spectrometer and Mass Spectrometry Method - A mass spectrum is generated by a process in which, from a mass scan signal comprising original samples defining a peak, a subset of the original samples defining the peak is selected. One or more synthesized samples are synthesized from the subset of the original samples. The one or more synthesized samples provide a temporal resolution greater than the temporal resolution of the original samples. The one or more synthesized samples are summed with respective temporally-aligned accumulated samples to produce the mass spectrum. The accumulated samples are obtained from mass scan signals generated during respective previously-performed mass scan operations. | 09-01-2011 |
August Jon Hidalgo, San Francisco, CA US
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20080296490 | TIME OF FLIGHT MASS SPECTROMETRY METHOD AND APPARATUS - A method and apparatus for performing time of flight mass spectrometry wherein the number of sums of transients taken for generating a given spectra is determined as a function of a characteristic of the incoming data for that spectrum. For instance, the number of transient measurements taken for a given spectrum output can be determined as a function of the abundance of ions in the sample or the abundance of ions corresponding to a base peak or another selected peak. In yet another embodiment, the collection of transients is terminated when a threshold signal to noise ratio is attained. | 12-04-2008 |
20080300800 | Mass Spectrometer and Method for Enhancing Resolution of Mass Spectra - A mass spectrometer comprises an ion detector, an analog-to-digital (A/D) converter, a sample adjuster, and an adder. The A/D converter is configured to generate digital samples representing an analog signal received from the ion detector during a mass scan. The adder is configured to sum the samples with corresponding unsuppressed samples representing analog signals received from the ion detector during previous mass scans, the summed samples defining a mass spectrum. The sample adjuster is configured to identify a peak defined by the samples and to suppress all but one of the samples defining the identified peak to enhance resolution of a peak in the mass spectrum. | 12-04-2008 |
20110175531 | PLASMA GENERATION DEVICE WITH SPLIT-RING RESONATOR AND ELECTRODE EXTENSIONS - A plasma generation device includes: a substrate having a first surface and a second surface; a stripline resonant ring disposed on the first surface of the substrate, and defining a discharge gap; a pair of electrode extensions connected to the stripline resonant ring at the discharge gap; a ground plane disposed on the second surface of the substrate; a gas flow element configured to flow gas between at least one of: (1) the discharge gap, and (2) the pair of electrode extensions; and a structure disposed adjacent the substrate to form an enclosure that substantially encloses at least a region including the discharge gap and the electrode extensions, the enclosure being adapted to contain a plasma. | 07-21-2011 |
Craig Hidalgo, Langhorne, PA US
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20110092952 | Shield Apparatuses and Methods For Storing Syringe Assemblies and Needle Assemblies - The present invention is directed to shield apparatuses configured to hold syringe assemblies in a manner that preserves their ease of use and convenience. In some embodiments, the syringe assemblies are detachable, and the shield apparatuses provide for convenient interchanging of the needle assemblies, as well as methods for administering injections to a patient. | 04-21-2011 |
20110178471 | Kits Comprising Syringe Assemblies - The present invention is directed to kits comprising syringe assemblies having detachable needle assemblies, as well as shield apparatuses to protect the needle assemblies. The syringe assemblies are configured to minimize the dead space after deployment of the syringe and injection of the material in the syringe into a patient's body, as well as to include detachable needle assemblies, such that different needle assemblies can be interchanged on a single syringe barrel. | 07-21-2011 |
20110202035 | Syringe Assemblies Having Detachable Needle Assemblies and Low Dead Space - The present invention is directed to syringe assemblies comprising detachable needle assemblies, that are configured in such a manner as to minimize the dead space after deployment of the syringe piston and injection of the material in the syringe into a patient's body, as well as with bevel indicators that provide guidance as to optimal angles at which to inject the needles into patients. | 08-18-2011 |
20130042425 | Applicator and Bucket for Cleaning Pads - An applicator for use in cleaning surfaces, comprising: a bottom surface; a handle disposed above the bottom surface; means for releasably attaching a pad to the bottom surface; and an actuator, accessible from the handle, for actuating the means for releasably attaching the pad to the bottom surface. The means for releasably attaching preferably has a plurality of feet which move between a first position within the applicator to a second position outside the applicator. When the feet are in the second position they can contact a cleaning pad. The feet include means (such as a hook-and-loop fastener) for gripping the cleaning pad, so that when the feet are in the second position, which is the at-rest position, they grip the cleaning pad. When the feet are moved to the first position, they release the pad, allowing for the disposal thereof without having to touch the soiled pad. | 02-21-2013 |
20130289586 | SURGICAL DEVICE - A wound closure device for closing a surgical wound includes at least one compressive clip for applying pressure to a patient's tissue. The clip includes a first clamping arm, a second clamping arm, and a flexible pin maintained between the first and second clamping arms in a press-fit relationship. Each of the first and second clamping arms has a proximal first end, an opposing distal second end and a sidewall extending therebetween. The clip has a first position in which the proximal first ends of the first and second clamping arms partially engage or do not engage each other and a second position in which the proximal first ends of the first and second clamping arms pivotally engage each other. In the second position of the clip, a compressive force generated at the proximal first ends is transferred through the first and second clamping arms to the distal second ends. | 10-31-2013 |
20130310856 | Suture Passer Guides and Related Kits and Methods - This disclosure relates to suture passer guides and related kits and methods. In certain aspects, a suture passer guide includes an elongate member and a suture positioning member that can be radially extended from a distal end region of the elongate member and rotated relative to the elongate member such that the suture positioning member can reposition a suture from a first side area of the elongate member to a second side area of the elongate member. | 11-21-2013 |
Craig A. Hidalgo, Langhorne, PA US
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20110087106 | Clamp for a Medical Probe Device - Disclosed are medical probe devices and methods for use guiding of percutaneous probes during medical procedures. The probe devices include a clamp that can secure a probe at a targeted location. The devices can be utilized to guide a probe through the probe guide to a percutaneous target. Disclosed clamps can be utilized on probe devices incorporating an ultrasound transducer. In addition, the devices can include a sterilizable shield including a sterile probe guide for use in procedures requiring a sterile field. The sterilizable shield can be a single-use shield that can prevent contamination and re-use of the shield. The devices can define a beneficial geometry conducive to use by a single operator that can be utilized for percutaneous targets near the skin surface. | 04-14-2011 |
20120041484 | MEDICAL DEVICE AND PROCEDURE FOR ATTACHING TISSUE TO BONE - The invention pertains to a method and apparatus for attaching tissue to bone. Particularly, the invention relates to bone anchors for receiving (or being pre-loaded with) sutures for connecting to soft tissue that is to be attached to bone, including tools for implanting the bone anchors and facilitating the attachment of soft tissue to bone via the bone anchors and procedures for using the same. | 02-16-2012 |
Craig Anthony Hidalgo, Langhorne, PA US
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20080201884 | Toothbrush Having Soft Tissue Cleaning Elements - An oral care implement includes a head and a plurality of cleaning elements for enhanced cleaning of the teeth and soft tissue of the oral cavity. One tooth cleaning element has a plurality of bristles adapted to clean teeth. Another cleaning element is connected to the head and has structure defining a channel. The channel is configured to direct fluid in contact with the head toward an edge of the head when the implement is moved. The head also defines a reservoir that is configured to receive a dentifrice therein. | 08-28-2008 |
David Hidalgo, Montverde, FL US
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20130189628 | Sustainable and Eco-Friendly Campfire Apparatus - The present invention provides a new and useful eco-friendly campfire apparatus. This apparatus comprises reclaimed and repurposed eco-friendly components and is believed to be useful by offering a complete set of materials needed to create a campfire which emits no toxic chemicals. The apparatus comprises a container which is a reclaimed and repurposed animal feed sack having a front wall and a back wall defining an interior therein. The container is sealed by using a sealing means which can be untreated natural twine or thread. Inside the container is a plurality of combustible materials that are generally uniformly dispersed and include reclaimed kiln-dried, natural, toxin-free, wood logs, reclaimed kindling including hickory nuts and twigs, and pine shavings. An igniting means is also provided and affixed to the exterior front wall of the apparatus. The self-contained nature of the apparatus makes it easy to transport and store when not in use. | 07-25-2013 |
Edison Hidalgo, Newark, DE US
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20090209426 | HERBICIDAL MIXTURE - A mixture of diuron with mesotrione optionally containing other herbicides such hexazinone is disclosed as useful for controlling undesired vegetation. Also disclosed is a herbicidal composition comprising diuron, mesotrione and optionally other herbicides such as hexazinone and at least one additional component selected from the group consisting of surfactants, solid diluents and liquid diluents. Further disclosed is a method of controlling undesired vegetation comprising applying to the locus of the vegetation a herbicidally effective amount of the mixture. | 08-20-2009 |
20100285959 | HERBICIDAL MIXTURES - Disclosed is a herbicidal mixture comprising (a) at least one herbicide compound selected from the pyrimidines of Formula 1, including all geometric and stereoisomers, N-oxides, and salts thereof: | 11-11-2010 |
20100317525 | HERBICIDAL MIXTURE - A mixture of diuron, hexazinone and tembotrione is disclosed as useful for controlling undesired vegetation. Also disclosed is a herbicidal composition comprising diuron, hexazinone and tembotrione, and at least one additional component selected from the group consisting of surfactants, solid diluents and liquid diluents. Further disclosed is a method of controlling undesired vegetation comprising applying to the locus of the vegetation a herbicidally effective amount of the mixture. | 12-16-2010 |
Gonzalo Hidalgo, Holly Springs, NC US
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20090138435 | TECHNIQUES FOR SEARCHING AND PRESENTING SEARCH RESULTS - Techniques for searching and presenting search results to a user are provided. A search is decomposed into sub search combinations. Logical operator ordering is maintained within each sub search combination and each sub search combination is processed to acquire a waterfall count for the resulting answer set associated with processing that sub search combination. The sub search combinations and their waterfall counts are then presented to the user for visual inspection and analysis. | 05-28-2009 |
Ismael J. Hidalgo, West Chester, PA US
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20100311082 | Stable Cell Lines and Methods for Evaluating Gastrointestinal Absorption of Chemicals - Nucleic acids and vectors for interfering with the expression of membrane efflux transport proteins in cells that express such proteins are provided. Also provided are cells and cell lines comprising such nucleic acids and vectors. Methods for screening chemicals and biomolecules for gastrointestinal absorption in animals, and kits for practicing such methods are also provided. | 12-09-2010 |
20100317049 | Stable Cell Lines and Methods for Evaluating Gastrointestinal Absorption of Chemicals - Nucleic acids and vectors for interfering with the expression of membrane efflux transport proteins in cells that express such proteins are provided. Also provided are cells and cell lines comprising such nucleic acids and vectors. Methods for screening chemicals and biomolecules for gastrointestinal absorption in animals, and kits for practicing such methods are also provided. | 12-16-2010 |
20120142008 | METHODS FOR EVALUATING GASTROINTESTINAL ABSORPTION OF CHEMICALS - Nucleic acids and vectors for interfering with the expression of membrane efflux transport proteins in cells that express such proteins are provided. Also provided are cells and cell lines comprising such nucleic acids and vectors. Methods for screening chemicals and biomolecules for gastrointestinal absorption in animals, and kits for practicing such methods are also provided. | 06-07-2012 |
Jorge E. Hidalgo, East Windsor, CT US
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20110048616 | LAMINATE ASSEMBLY SEALING METHOD AND ARRANGEMENT - An example method of sealing a laminate assembly includes preloading a laminate assembly having a plurality of laminations, pressurizing the laminate assembly, and pressurizing an enclosed volume disposed adjacent an end portion of the laminate assembly to hold the laminations in sealed positions. | 03-03-2011 |
20130312914 | LAMINATE ASSEMBLY SEALING METHOD AND ARRANGEMENT - An example laminate assembly pressurization arrangement includes a plurality of laminations arranged in a laminate stack. The plurality of laminations are movable between sealed positions and unsealed positions relative to each other. An end plate is adjacent the laminate stack. A housing is configured to establish a first volume together with the end plate. A first group of tie rods is directly secured to the end plate and is configured to move the end plate to a first position that holds the plurality of laminations in sealed positions. A second group of tie rods is directly secured to the housing. Pressurizing the first volume limits movement of the end plate away from the first position. | 11-28-2013 |
Jorge E. Hidalgo, Suffield, CT US
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20130221161 | SINGLE HINGE SPACESUIT AND VEHICLE PORT INTERFACE - An extravehicular activity system includes a vehicle having a bulkhead providing a port. The bulkhead separates an interior environment and an unenclosed exterior environment. The exterior environment is configured to be exposed to atmospheric pressure in a donning condition. A cover has a perimeter with a side of the perimeter secured to the bulkhead by a hinged joint. A spacesuit is supported on the bulkhead in the exterior environment and includes a flange providing a rear entry opening aligned with the port. A PLSS is retained in the cover and spaced from the flange in the donning condition. The PLSS is configured to be rotated about the hinged joint and into engagement with the flange in a donned condition in which the PLSS is removably secured to the flange. | 08-29-2013 |
20150068416 | LOW PROFILE LAMINATE ASSEMBLIES - An assembly has a plurality of laminate components aligned atop each other. A first endplate is at one end of the assembly of components and a second endplate is at an opposed end. The first and second endplates have outer surfaces facing away from the components. A spring force applies a compressive force to bias the first and second endplates together and, in turn, apply a force across the laminate components. The spring force is provided by a spring mounted between the outer surfaces of the first and second endplates. | 03-12-2015 |
20150176767 | CONDENSATION REDUCTION AROUND CRYOGENIC SERVICE CONNECTION - The system has a cryogenic tank and a connection for supplying a first fluid to the cryogenic tank. The fluid connection is provided with at least one valve which may be selectively opened to receive the fluid and one valve for venting. A vacuum chamber housing is positioned on an opposed side of the valve from the tank. A vacuum source is operated to remove leaking fluid from the vacuum housing while the first fluid is being supplied through the valve to the tank in order to minimize heat leaks to the transfer tube. A method is also disclosed. | 06-25-2015 |
Julie A. Hidalgo, West Islip, NY US
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20110238604 | COMPUTER-AIDED DIAGNOSTIC SYSTEMS AND METHODS FOR DETERMINING SKIN COMPOSITIONS BASED ON TRADITIONAL CHINESE MEDICINAL (TCM) PRINCIPLES - Computer-aided systems and methods are provided for determining the skin composition of a specific user according to Traditional Chinese Medicinal (TCM) principles by statistically analyzing biological and/or psychological information collected from such user, such as age, gender, bodily sensation, skin condition and complexion, sleep pattern, dietary habits, energy level, stress level, physical fitness and emotional wellness, so as to classify the skin composition of the user according to TCM principles but without employing a TCM practitioner. Preferably, the skin composition classification is indicative of Yin-Yang balance of the skin of the user or the lack thereof. The present systems and methods may further recommend to the user one or more topical skin care regimens and/or ingestible skin benefit products suitable for the skin composition of the specific user. | 09-29-2011 |
Manuel Hidalgo, Baltimore, MD US
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20090099218 | SYNTHESIS OF NOVEL TUBULIN POLYMERIZATION INHIBITORS: BENZOYLPHENYLUREA (BPU) SULFUR ANALOGS - This invention provides a series of BPU analogues; their synthesis and evaluated biological activity. BPU sulfur analogues were found to possess up to 20 fold increased potency, when compared to compound 1, in various cancerous cell lines. | 04-16-2009 |
20090221522 | METHODS TO CORRECT GENE SET EXPRESSION PROFILES TO DRUG SENSITIVITY - The present invention comprises a treatment approach based on gene set-expression signatures that systematically connects a sample to a profile from a reference database to extrapolate the most effective therapeutic agent. Further disclosed are methods to optimize combination treatments. | 09-03-2009 |
20100113491 | SYNTHESIS OF NOVEL TUBULIN POLYMERIZATION INHIBITORS: BENZOYLPHENYLUREA (BPU) SULFUR ANALOGS - A novel series of BPU analogues were synthesized and evaluated for antitumor activity. In particular, BPU sulfur analogues 6n and 7d were shown to possess up to 10-fold increased potency, when compared to compound 1, against cancer cell lines. 6n was more effective than compound 1 in causing apoptosis of MCF-7 cells. When compared to other drugs with a similar mechanism of action, 6n retained significant ability to inhibit tubulin assembly, with an IC50 of 2.1 μM. | 05-06-2010 |
20120034318 | DIAGNOSTIC METHOD USING PALB2 - The present invention provides a method for detecting mutations in the PALB2 gene in pancreatic cancer patients and in individuals having a family history of pancreatic cancer. Methods are also provided for diagnosing a predisposition to pancreatic cancer, for predicting a patient's response to pancreatic cancer therapies, and for treating pancreatic cancer, based on presence of a PALB2 mutation or abberant PALB2 gene expression in a patient. | 02-09-2012 |
Manuel M. Hidalgo, Baltimore, MD US
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20080293069 | RAPID PROGNOSTIC ASSAY FOR MALIGNANCIES TREATED WITH EPIDERMAL GROWTH FACTOR RECEPTOR - A molecular assay for determining the sensitivity or resistance of malignancies to chemotherapy prior to initiation of chemotherapy and which also allows for monitoring the therapeutic effects of the chemotherapy during treatment. The molecular assay measures tumor response to therapy with EGFR modulators and utilizes tumor mRNA as a starting material and a quantitative measurement of c-fos expression as an analytical endpoint. | 11-27-2008 |
Manuel Medina Hidalgo, Baltimore, MD US
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20110201675 | ON01910.Na ENHANCES CHEMOTHERAPEUTIC AGENT ACTIVITY IN DRUG-RESISTANT TUMORS - The invention includes compositions and methods of treatment of cancers susceptible to treatment with nucleotide analog chemotherapeutic agent, including cancers in which nucleotide analog resistant tumors have developed, including identifying a subject having cancer susceptible to treatment with a nucleotide analog chemotherapeutic agent and a mitotic disruptor/polo-like kinase (Plk) pathway inhibitor to a subject; and monitoring the subject for a reduction or stabilization of at least one sign or symptom of cancer. | 08-18-2011 |
20150209381 | ON01910.Na ENHANCES CHEMOTHERAPEUTIC AGENT ACTIVITY IN DRUG-RESISTANT TUMORS - The invention includes compositions and methods of treatment of cancers susceptible to treatment with nucleotide analog chemotherapeutic agent, including cancers in which nucleotide analog resistant tumors have developed, including identifying a subject having cancer susceptible to treatment with a nucleotide analog chemotherapeutic agent and a mitotic disruptor/polo-like kinase (PIk) pathway inhibitor to a subject; and monitoring the subject for a reduction of stabilization of at least one sign or symptom of cancer. | 07-30-2015 |
Mario Hidalgo, Phoenix, AZ US
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20130318995 | SYSTEMS AND METHODS FOR DIRECTING COOLING FLOW INTO THE SURGE PLENUM OF AN EXHAUST EDUCTOR COOLING SYSTEM - An eductor assembly comprises a primary nozzle configured to discharge turbine exhaust gas therefrom. The eductor assembly further comprises a cooler plenum having an inlet and an outlet and a surge plenum at least partially surrounding the cooler plenum and the nozzle, the surge plenum for conducting a surge flow. Cooling air flows through a vent between the cooler plenum and the surge plenum when there is no surge flow. | 12-05-2013 |
Mary Hidalgo, Costa Mesa, CA US
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20100142209 | Light Tower Diffuser - The invention provides a diffuser for a portable light tower that has an envelope of fire resistant material designed to diffuse light situated on a frame forming a generally spherical structure that can be opened and closed by use of a pulley and cable system. | 06-10-2010 |
Patches Duana Hidalgo, Woodburn, OR US
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20150250985 | WRAPS - Wraps configured to cover a user's body portion having a tube that is at least partially external the user's body and that is in fluid communication with one or more internal systems of the user's body are disclosed. The wraps may include a fabric panel sized and shaped to wrap around and cover the user's body portion. The wraps may additionally include a coupling assembly connected to the fabric panel and configured to secure the fabric panel to one or more portions of the user when the fabric panel is wrapped around the user's body portion. The wraps may further include a holder assembly configured to secure a portion of the tube to the fabric panel. | 09-10-2015 |
Rafael Enrique Hidalgo, Fort Mill, SC US
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20140265045 | Chute for Laser Sintering Systems - There is provided improved laser sintering systems that increase the powder density and reduce anomalies of the powder layers that are sintered, that measure the laser power within the build chamber for automatic calibration during a build process, that deposit powder into the build chamber through a chute to minimize dusting, and that scrubs the air and cools the radiant heaters with recirculated scrubbed air. The improvements enable the laser sintering systems to make parts that are of higher and more consistent quality, precision, and strength, while enabling the user of the laser sintering systems to reuse greater proportions of previously used but unsintered powder. | 09-18-2014 |
20140271326 | Powder Distribution for Laser Sintering Systems - There is provided improved laser sintering systems that increase the powder density and reduce anomalies of the powder layers that are sintered, that measure the laser power within the build chamber for automatic calibration during a build process, that deposit powder into the build chamber through a chute to minimize dusting, and that scrubs the air and cools the radiant heaters with recirculated scrubbed air. The improvements enable the laser sintering systems to make parts that are of higher and more consistent quality, precision, and strength, while enabling the user of the laser sintering systems to reuse greater proportions of previously used but unsintered powder. | 09-18-2014 |