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Hetherington, US

Hoby Hetherington, Woodbridge, CT US

Patent application numberDescriptionPublished
20110260727Shim insert for high-field MRI magnets - The present invention is a portable in-bore shim coil insert suitable for correcting high-degree and high-order magnetic field inhomogeneities over a limited examination zone in a magnetic resonance assembly operating above 3 T magnetic field strengths, wherein the magnetic resonance assembly includes at least a MRI magnet having an internal bore of known configuration and volume, at least one set of gradient coils, and an arrangement of radio frequency coils. The in-bore shim coil insert and corresponding method of use is able to produce higher degree and order shimming effects on-demand (i.e., the correction of at least some 310-27-2011

Hoby P. Hetherington, Woodbridge, CT US

Patent application numberDescriptionPublished
20080258725Non iterative shimming in magnetic resonance imaging in the presence of high LIPID levels - For the brain, a variety of automated non-iterative shimming methods using phase evolution derived B10-23-2008
20090302841Surface Coil Arrays for Simultaneous Reception and Transmission with a Volume Coil and Uses Thereof - This invention provides arrays of counter rotating current surface coils for simultaneous reception and transmission with a volume coil for improved signal-to-noise ratio and radio frequency field homogeneity for in particular high-field (4-8 T) imaging of deep body regions, such as central brain structures.12-10-2009

Hugh E. Hetherington, Bozeman, MT US

Patent application numberDescriptionPublished
20090254046Injection control method and device - An injection control device having a metered/controlled injection rate proportional to the rate of withdrawal/injection, suitable for cosmetic as well as other applications is described. For example, after the cannula is advanced into an object, the cannula is withdrawn to create a tract or tunnel within the targeted area. As the cannula is withdrawn, filler material in the injection control device is uniformly deposited into the tract or tunnel via the automatic metering system. The automatic metering system incorporates a syringe activating mechanism coupled to a system which is capable of proportioning the deposition rate to the retraction/injection rate of the cannula. Accordingly, more consistent and uniform distribution of the material injected can be achieved with less cannula passes as well as requiring less dependence on the skills of the practitioner of this device.10-08-2009
20090254048Injection control device with gearing mechanism - An injection control device having a metered/controlled injection rate, that is proportional to the rate of withdrawal/injection—suitable for cosmetic as well as other applications—is described. For an injection mode, after the cannula is advanced into an object, the cannula is withdrawn to create a tract or tunnel within the targeted area. As the cannula is withdrawn, filler material in the injection control device is uniformly deposited into the tract or tunnel via the automatic metering system. The automatic metering system incorporates a syringe activating mechanism coupled to a gearing system which is capable of proportioning the deposition (or sucking) rate to the retraction/injection rate of the cannula. Accordingly, more consistent and uniform distribution (or harvesting) of material can be achieved with less cannula passes as well as requiring less dependence on the skills of the practitioner of this device.10-08-2009
20090254060Motor assembly for injection control device - A spring motor mechanism for use in an injection control device having a metered/controlled injection rate proportional to the rate of withdrawal/injection suitable for cosmetic as well as other applications is described. After the cannula is advanced into an object (person) the cannula is withdrawn to create a tract or tunnel within the targeted area. As the cannula is withdrawn, filler material in the injection control device is uniformly deposited into the tract or tunnel via the automatic metering system. As one feature, the spring motor mechanism automatically retracts the positioning guide that is used in the metering systtem. The spring motor mechanism may be replaceable or customizable, offering the user enhanced safety and convenience of operation for the injection control device.10-08-2009
20090275900Syringe for injection control device - A specially designed syringe, without the need for finger holds is described, for use in an injection control device. The specially designed syringe is tailored for easy loading and use with the injection control device. The injection control device provides a metered or controlled injection and/or extraction rate proportional to the rate of withdrawal/injection of the body of the injection control device. The automatic metering system incorporates a syringe activating mechanism coupled to a system which is capable of proportioning the deposition rate to the retraction/injection rate of the cannula. Accordingly, more consistent and uniform distribution of the material injected can be achieved with less cannula passes as well as requiring less dependence on the skills of the practitioner of this device.11-05-2009

I. Lee Hetherington, Cambridge, MA US

Patent application numberDescriptionPublished
20100121642Speech Data Retrieval Apparatus, Speech Data Retrieval Method, Speech Data Retrieval Program and Computer Usable Medium Having Computer Readable Data Retrieval Program Embodied Therein - A speech data retrieval apparatus (05-13-2010

Michael Hetherington, Williamston, MI US

Patent application numberDescriptionPublished
20090029325VIRTUAL LOCOMOTIVE SIMULATION SYSTEM AND METHOD - A complete hardware and software railroad training system gives the trainee a hands-on operators experience in a safe and productive classroom environment. The system and method combines a complete virtual simulation of a yard and the associated equipment with a cost-effective Operator Control Unit (OCU) to fully address Remote Control Operation (RCO), including equipment handing, yard familiarization, rules and safety training. A simulated locomotive training system according to the invention comprises a computer system generating a display of an avatar in a simulated railroad environment including a virtual locomotive and associated equipment. The OCU, a hand-held unit in communication with the computer system, includes one or more video-game or “game-pad” type controls, enabling a user to manipulate the avatar in the simulated railroad environment. The controls may be joystick controllers, allowing a user to navigate, view and select objects and actions in the simulated railroad environment without the user's hands having to leave the OCU. Right and left controls, each operated by one finger on each of a user's hands, respectively direct the movement of the avatar in the simulated railroad environment and change the view of the avatar in the simulated railroad environment.01-29-2009

Patent applications by Michael Hetherington, Williamston, MI US

Paul Hetherington, Brewster, NY US

Patent application numberDescriptionPublished
20090213382OPTICAL RESONANCE ANALYSIS UNIT - An array surface plasmon resonance (SPR) analysis instrument comprising a reflective SPR sensor array, a light source assembly arranged to project a collimated beam of light onto the reflective SPR sensor array to provide a reflected array image of the sensor array, and to scan the incident angle of the collimated beam of light over an angular range, and a detector assembly oriented to receive the reflected array image of the sensor array over the angular range, the detector assembly comprises a two-dimensional detector sensing element that is tilted with respect to the optical axis of the lens assembly in accordance with the Scheimpflug condition, and a lens assembly for focusing the reflected array image of said SPR sensor array onto said tilted detector sensing element. The lens assembly comprises an objective section which is arranged to produce a virtual image of the tilted reflected array at infinity, followed by an imaging section arranged to transform the virtual image of the tilted reflected array into a real tilted image on the tilted detector sensing element.08-27-2009

Paul M. Hetherington, Goldens Bridge, NY US

Patent application numberDescriptionPublished
20080314431Thermal cycler for PCR - An instrument for performing highly accurate PCR employing an assembly, a heated cover, and an internal computer, is provided. The assembly is made up of a sample block, a number of Peltier thermal electric devices, and a heat sink, clamped together. A control algorithm manipulates the current supplied to thermoelectric coolers such that the dynamic thermal performance of a block can be controlled so that pre-defined thermal profiles of sample temperature can be executed. The sample temperature is calculated instead of measured using a design specific model and equations. The control software includes calibration diagnostics which permit variation in the performance of thermoelectric coolers from instrument to instrument to be compensated for such that all instruments perform identically. The block/heat sink assembly can be changed to another of the same or different design. The assembly carries the necessary information required to characterize its own performance in an on-board memory device, allowing the assembly to be interchangeable among instruments while retaining its precision operating characteristics.12-25-2008
20100173400Thermal Cycler for PCR - An instrument for performing highly accurate PCR employing an assembly, a heated cover, and an internal computer, is provided. The assembly is made up of a sample block, a number of Peltier thermal electric devices, and a heat sink, clamped together. A control algorithm manipulates the current supplied to thermoelectric coolers such that the dynamic thermal performance of a block can be controlled so that pre-defined thermal profiles of sample temperature can be executed. The sample temperature is calculated instead of measured using a design specific model and equations. The control software includes calibration diagnostics which permit variation in the performance of thermoelectric coolers from instrument to instrument to be compensated for such that all instruments perform identically. The block/heat sink assembly can be changed to another of the same or different design. The assembly carries the necessary information required to characterize its own performance in an on-board memory device, allowing the assembly to be interchangeable among instruments while retaining its precision operating characteristics.07-08-2010

Patent applications by Paul M. Hetherington, Goldens Bridge, NY US

Richard W. Hetherington, Bend, OR US

Patent application numberDescriptionPublished
20100154326LIFT HANDLE SYSTEM FOR FENESTRATION PRODUCTS AND THE LIKE - Lifting systems and processes for building systems, including fenestration devices such as door and window units. One such system includes a fenestration device having a nailing fin and a lift handle attached to the nailing fin. The handle includes a channel disposed proximate a flange of the lift handle.06-24-2010

Patent applications by Richard W. Hetherington, Bend, OR US

Ricky C. Hetherington, Pleasanton, CA US

Patent application numberDescriptionPublished
20100293420CACHE COHERENT SUPPORT FOR FLASH IN A MEMORY HIERARCHY - System and method for using flash memory in a memory hierarchy. A computer system includes a processor coupled to a memory hierarchy via a memory controller. The memory hierarchy includes a cache memory, a first memory region of random access memory coupled to the memory controller via a first buffer, and an auxiliary memory region of flash memory coupled to the memory controller via a flash controller. The first buffer and the flash controller are coupled to the memory controller via a single interface. The memory controller receives a request to access a particular page in the first memory region. The processor detects a page fault corresponding to the request and in response, invalidates cache lines in the cache memory that correspond to the particular page, flushes the invalid cache lines, and swaps a page from the auxiliary memory region to the first memory region.11-18-2010
20100332727EXTENDED MAIN MEMORY HIERARCHY HAVING FLASH MEMORY FOR PAGE FAULT HANDLING - A computer system with flash memory in the main memory hierarchy is disclosed. In an embodiment, the computer system includes at least one processor, a memory management unit coupled to the at least one processor, and a random access memory (RAM) coupled to the memory management unit. The computer system may also include a flash memory coupled to the memory management unit, wherein the computer system is configured to store at least a subset of a plurality of pages in the flash memory during operation. Responsive to a page fault, the memory management unit may determine, without invoking an I/O driver, if a requested page associated with the page fault is stored in the flash memory and further configured to, if the page is stored in the flash memory, transfer the page into RAM.12-30-2010

Patent applications by Ricky C. Hetherington, Pleasanton, CA US

Seth Hetherington, Alpharetta, GA US

Patent application numberDescriptionPublished
20090306099Method of Screening for Drug Hypersensitivity Reaction - Methods of assessing the risk of clinical signs of hypersensitivity reaction to nucleoside antiviral compounds, including abacavir, are described. The methods include genotyping subjects for polymorphisms in the TNFα gene, the class 1 HLA genes, or a combination of both the TNFα and HLA genes.12-10-2009