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Herr, US

Adam Herr, Portland, OR US

Patent application numberDescriptionPublished
20100122208Panoramic Mapping Display - An interactive software application employs visual confirmation of location information to construct visual routes on a map without the need for separate location-measuring devices. This enables the recording of tours of interiors or other locations where conventional location data such as from a GPS system is unavailable, and the use of even inaccurate or arbitrary maps. The preferred embodiment uses panoramic or immersive motion picture tracks because they contain the most comprehensive amount of information about the location. In drawing the routes of the movies on a floor plan, the user starts with the image of a location to confirm the starting point, then establishes keypoints along the way, locking selected time points of the movies to spatial locations in the map. Other controls change the shape of the routes on the map, or the rate of travel between the keypoints. The result is an interactive, comprehensive tour of a space that can be packaged as an interactive project for distribution locally or as a web service.05-13-2010

Adam Herr, Forest Grove, OR US

Patent application numberDescriptionPublished
20100050221Image Delivery System with Image Quality Varying with Frame Rate - An image delivery system responds to limits of bandwidth by changing the resolution of the delivered image according to the frame rate required. For a motion picture image, the resolution is reduced in order to maintain the frame rate, and if the image is paused, a maximum image resolution is loaded instead during the time the image is not being updated. For immersive imaging systems, there is a similar adjustment of resolution according to frame rate and the bandwidth requirements, and the user is free to look around, either inside a motion picture at reduced resolution or a paused image at a higher resolution. This higher resolution is typically seen in a movable region of interest window extracted from the larger immersive image.02-25-2010

Adam W. Herr, Forest Grove, OR US

Patent application numberDescriptionPublished
20110292058NON-VOLATILE STORAGE FOR GRAPHICS HARDWARE - Methods and systems may provide for an apparatus having a graphics processing unit (GPU) and a non-volatile memory dedicated to the GPU. If a request for content is detected, a determination may be made as to whether the non-volatile memory contains the content.12-01-2011

Amanda C. Herr, St. Louis, MO US

Patent application numberDescriptionPublished
20100248963Encapsulation of Herbicides to Reduce Crop Injury - Methods of reducing injury to crop foliage and achieving weed control using encapsulated acetamide herbicides are described. Herbicidal microcapsules comprising herbicide core material and a shell wall encapsulating the core material are also described. The microcapsules provide reduced crop injury through controlled herbicide release.09-30-2010

Amy E. Herr, Oakland, CA US

Patent application numberDescriptionPublished
20100196941Multi-Analyte Analysis of Saliva Biomarkers as Predictors of Periodontal and Pre-Implant Disease - The present invention relates to methods of measuring biomarkers to determine the probability of a periodontal and/or peri-implant disease. More specifically, the invention provides a panel of biomarkers that, when used in combination, can allow determinniation of the probability of a periodontal and/or peri-implant disease state with extremely high accuracy.08-05-2010
20110177618Multi-Directional Microfluidic Devices and Methods - Multi-directional microfluidic devices and methods for using the same are provided. Aspects of the invention include microfluidic devices that are configured to subject a sample to two or more directionally distinct flow fields, and include a separation medium and a binding medium, where the binding medium is in fluid communication with the separation medium. Also provided are methods of using the devices as well as systems and kits that include the devices. The devices, systems and methods find use in a variety of different applications, including diagnostic and validation assays.07-21-2011
20120135541MULTI-DIRECTIONAL MICROFLUIDIC DEVICES COMPRISING A PAN-CAPTURE BINDING REGION AND METHODS OF USING THE SAME - Microfluidic devices and methods for using the same are provided. Aspects of the invention include microfluidic devices that include a separation medium and a pan-capture binding medium. The microfluidic devices are configured to subject a sample to two or more directionally distinct electric fields. Also provided are methods of using the devices as well as systems and kits that include the devices. The devices, systems and methods find use in a variety of different applications, including diagnostic and validation assays.05-31-2012

Patent applications by Amy E. Herr, Oakland, CA US

Andrew B. Herr, Cincinnati, OH US

Patent application numberDescriptionPublished
20100317536CRYSTAL STRUCTURE OF HUMAN GPVI AND APPLICATIONS THEREOF - A crystal comprising the collagen binding domain of human GPVI is provided and defined by structural atomic coordinates. Employing computer modeling based on the crystal structure, including methods for identifying inhibitors of GPVI collagen binding activity, methods for screening libraries of compounds for potential to bind to the GPVI collagen binding domain, and methods of identifying a compound useful for the treatment of a GPVI-mediated disorder, are also provided.12-16-2010
20110189260USE OF ZINC CHELATORS TO INHIBIT BIOFILM FORMATION - A method is provided for inhibiting formation of a biofilm of bacteria, the method including contacting the bacteria with an effective amount of at least one zinc chelator, wherein the bacteria contain at least one zinc adhesion module, whereby formation of the biofilm is inhibited. A method for inhibiting biofilm formation on a device and a topical pharmaceutical composition for the inhibition of biofilm formation are also provided.08-04-2011
20120135880Crystal of Human Glycoprotein VI Collagen Binding Domain - A crystal comprising the collagen binding domain of human GPVI is provided and defined by structural atomic coordinates. Employing computer modeling based on the crystal structure, including methods for identifying inhibitors of GPVI collagen binding activity, methods for screening libraries of compounds for potential to bind to the GPVI collagen binding domain, and methods of identifying a compound useful for the treatment of a GPVI-mediated disorder, are also provided.05-31-2012

Patent applications by Andrew B. Herr, Cincinnati, OH US

Anna Y. Herr, Ellicott City, MD US

Patent application numberDescriptionPublished
20100033206METHOD AND APPARATUS FOR BALLISTIC SINGLE FLUX QUANTUM LOGIC - In one embodiment, the disclosure relates to a single flux quantum (SFQ) signal transmission line powered by an AC power source. The AC power source supplies power to a transformer having a primary winding and a secondary winding. The primary winding receives the AC signal and the secondary winding communicates the signal to the SFQ transmission line. The transmission line can optionally include an input filter circuit for receiving the incoming SFQ pulse. The filter circuit can have a resistor and an inductor connected in parallel. In an alternative arrangement, the filter circuit can comprise of an inductor. A first Josephson junction can be connected to the filter circuit and to the secondary winding. The Josephson junction triggers in response to the incoming SFQ pulse and regenerates a pulse signal in response to a power discharge from the secondary winding.02-11-2010
20100207657Method and Apparatus for Ballistic Single Flux Quantum Logic - In one embodiment, the disclosure relates to a single flux quantum (SFQ) signal transmission line powered by an AC power source. The AC power source supplies power to a transformer having a primary winding and a secondary winding. The primary winding receives the AC signal and the secondary winding communicates the signal to the SFQ transmission line. The transmission line can optionally include an input filter circuit for receiving the incoming SFQ pulse. The filter circuit can have a resistor and an inductor connected in parallel. In an alternative arrangement, the filter circuit can comprise of an inductor. A first Josephson junction can be connected to the filter circuit and to the secondary winding. The Josephson junction triggers in response to the incoming SFQ pulse and regenerates a pulse signal in response to a power discharge from the secondary winding.08-19-2010
20100237899Method and Apparatus for Ballistic Single Flux Quantum Logic - In one embodiment, the disclosure relates to a single flux quantum (SFQ) signal transmission line powered by an AC power source. The AC power source supplies power to a transformer having a primary winding and a secondary winding. The primary winding receives the AC signal and the secondary winding communicates the signal to the SFQ transmission line. The transmission line can optionally include an input filter circuit for receiving the incoming SFQ pulse. The filter circuit can have a resistor and an inductor connected in parallel. In an alternative arrangement, the filter circuit can comprise of an inductor. A first Josephson junction can be connected to the filter circuit and to the secondary winding. The Josephson junction triggers in response to the incoming SFQ pulse and regenerates a pulse signal in response to a power discharge from the secondary winding.09-23-2010
20110267878Josephson Magnetic Random Access Memory System and Method - One aspect of the present invention includes a Josephson magnetic random access memory (JMRAM) system. The system includes an array of memory cells arranged in rows and columns. Each of the memory cells includes an HMJJD that is configured to store a digital state corresponding to one of a binary logic-1 state and a binary logic-0 state in response to a word-write current that is provided on a word-write line and a bit-write current that is provided on a bit-write line. The HMJJD is also configured to output the respective digital state in response to a word-read current that is provided on a word-read line and a bit-read current that is provided on a bit-read line.11-03-2011

Brian D. Herr, Rhinebeck, NY US

Patent application numberDescriptionPublished
20090019098FILE SYSTEM MOUNTING IN A CLUSTERED FILE SYSTEM - A method effectively preventing a requesting node from unfencing and mounting a file system subsequent to a failure in a cluster file system having a plurality of active nodes. The method comprising first upgrading one active node in the cluster to function as a cluster manager node. The cluster manager is in communication with all nodes. The cluster manager is assigned manager responsibilities, in part, comprising first receiving an active status request from the node requesting to mount a file system. The cluster manager first queries the quorum nodes to determine whether each node considers the cluster manager to still have cluster management responsibilities for the file system. If a majority of quorum nodes consider the cluster manager to still have cluster management responsibilities for the file system then the cluster manager responds to the requesting node's active status request. Thereafter, the requesting node proceeds with mounting the file system.01-15-2009

Patent applications by Brian D. Herr, Rhinebeck, NY US

Charles F. Herr, Amherst, NY US

Patent application numberDescriptionPublished
20120014788DIFFUSER USING DETACHABLE VANES - A system, in certain embodiments, includes a plurality of detachable, three-dimensional diffuser vanes attached to a diffuser plate of a centrifugal compressor. In certain embodiments, the detachable, three-dimensional diffuser vanes may be attached to the diffuser plate using threaded fasteners. In addition, dowel pins may be used to align the detachable, three-dimensional diffuser vanes with respect to the diffuser plate. However, in other embodiments, the detachable, three-dimensional diffuser vanes may include a tab configured to fit securely within a groove in the diffuser plate. In addition, the tabs of the detachable, three-dimensional diffuser vanes may include indentions that mate with extensions extending from the diffuser plate, wherein the tabs may slide into slots between the extensions and the grooves of the diffuser plate.01-19-2012
20120014801DIFFUSER HAVING DETACHABLE VANES WITH POSITIVE LOCK - A system, in certain embodiments, includes a centrifugal compressor diffuser that includes an elliptical plate including multiple vane receptacles disposed about an axis of the plate and multiple detachable vanes attached to the plate. Each vane receptacle includes a first two dimensional (2D) projection along a plane of the elliptical plate and each detachable vane includes a second two dimensional (2D) projection along a base portion of the vane, where each detachable vane is disposed in a respective vane receptacle with the first and second 2D projections blocking movement of the detachable vane in at least a first axial direction relative to the elliptical plate. In certain embodiments, the first and second 2D projections may include a first tab to fit in a recess between a pair of second tabs, respectively, or vice versa. However, in other embodiments, the first and second 2D projections may include alternative mating surfaces.01-19-2012

Daniel J. Herr, Twinsburg, OH US

Patent application numberDescriptionPublished
20090236534Pixelated Scintillation Detector and Method of Making Same - A scintillation detector may include a pixelated scintillation crystal mechanically and optically coupled to a position sensitive photodetector, such as a position sensitive photomultiplier tube (PSPMT). The pixelated scintillation crystal may be coupled to the position sensitive photodetector without using a window between the crystal and photodetector. According to one method of constructing the scintillation detector, a solid scintillation crystal may be coupled to the position sensitive photodetector and cut while coupled to the photodetector to form the pixelated scintillation crystal.09-24-2009
20110253290PIXELATED SCINTILLATION DETECTOR AND METHOD OF MAKING SAME - A scintillation detector may include a pixelated scintillation crystal mechanically and optically coupled to a position sensitive photodetector, such as a position sensitive photomultiplier tube (PSPMT). The pixelated scintillation crystal may be coupled to the position sensitive photodetector without using a window between the crystal and photodetector. According to one method of constructing the scintillation detector, a solid scintillation crystal may be coupled to the position sensitive photodetector and cut while coupled to the photodetector to form the pixelated scintillation crystal.10-20-2011
20120043458RUGGEDIZED TOOL AND DETECTOR DEVICE - A tool comprising a tool body having an opening defined by interior walls extending into the tool body and a casing disposed within the opening. The tool further includes a scintillator material disposed within the casing and a first compressive member disposed within the tool body at a first axial location. The first axial location extends for a fraction of a total axial length of the casing and exerts a first radially compressive force at the first axial location.02-23-2012

Patent applications by Daniel J. Herr, Twinsburg, OH US

Daniel P. Herr, South Windsor, CT US

Patent application numberDescriptionPublished
20100191548Computer Method and System for Administering Investment Account - A computerized method for administering an investment account having an income or withdrawal guarantee and long term care guarantee includes the steps of establishing an investment account having an account balance, allocating a first portion of the account balance to fund a periodic long term care benefit having a long term care benefit guarantee, allocating a second portion of the account to fund a periodic income or withdrawal benefit having an income or withdrawal benefit guarantee, determining an amount of a periodic long term care benefit available for payment of a long term care benefit claims under the long term care benefit guarantee, and determining an amount of a periodic income or withdrawal benefit available for distribution under the income or withdrawal benefit guarantee. The long term care benefit guarantee may include an acceleration of benefits guarantee and an extension of benefits guarantee. A computer system which includes a processor and a program for causing the processor to perform certain steps is also disclosed.07-29-2010

David Herr, Golden, CO US

Patent application numberDescriptionPublished
20100217497USER INPUT FOR VEHICLE CONTROL - A user input for controlling acceleration of a vehicle. The user input has a movable member capable of deflection by a user such that a degree of deflection corresponds to a specified velocity commanded by the user. The correspondence between the degree of deflection and the specified velocity may include a plurality of zones, each zone characterized by a distinct sensitivity that may be capable of customization for a specific user. The user input may also include a neutral position of the movable member, wherein a substantially sudden motion of the movable member to the neutral position causes a slewed slowing of the vehicle.08-26-2010

David Herr, Compton, NH US

Patent application numberDescriptionPublished
20080319627USER INPUT FOR VEHICLE CONTROL - A user input for controlling acceleration of a vehicle. The user input has a movable member capable of deflection by a user such that a degree of deflection corresponds to a specified velocity commanded by the user. The correspondence between the degree of deflection and the specified velocity may include a plurality of zones, each zone characterized by a distinct sensitivity that may be capable of customization for a specific user. The user input may also include a neutral position of the movable member, wherein a substantially sudden motion of the movable member to the neutral position causes a slewed slowing of the vehicle.12-25-2008

David A. Herr, Apex, NC US

Patent application numberDescriptionPublished
20110047276ACCEPT AND RECEIVE ENHANCEMENTS - A server issues an enhanced accept and receive call to a client computer. The enhanced accept and receive call requires the server to subsequently receive a block of data from the client computer in order to establish a session connection between the client computer and a server resource. In response to the block of data from the client computer failing to be received by the server, the server prevents the session connection from being pushed onto an accept queue on the server until the server executes a corrective process.02-24-2011

Deron R. Herr, San Diego, CA US

Donald Herr, Lancaster, PA US

Patent application numberDescriptionPublished
20120082840THERMALLY REVERSIBLE HOT MELT ADHESIVE COMPOSITION CONTAINING MULTIFUNCTIONAL DIENE AND DIENOPHILE COMPOUNDS - The invention relates to a thermally reversible hot melt adhesive that is isocyanate-free, moisture independent, crosslinkable and thermally reversible. The thermally reversible hot melt adhesive may be repeatedly heated and cooled without negatively affecting the performance of the adhesive. The thermally reversible composition may also be used as a primer layer. The thermally reversible hot melt adhesive and primer are particularly well suited for end use applications such as packaging, graphic arts, construction, footwear, textiles, general assembly, automotive and consumer goods.04-05-2012

Donald E. Herr, Doylestown, PA US

Patent application numberDescriptionPublished
20100155247RADIATION-CURABLE RUBBER ADHESIVE/SEALANT - A radiation-curable adhesive/sealant composition comprises a radiation-curable rubber resin, one or more photoinitiators or photosensitizers, and optionally, one or more inorganic or organic fillers.06-24-2010
20100168279THERMALLY CURABLE EPOXY-AMINE BARRIER SEALANTS - This invention is a barrier composition comprising a resin or resin/filler system that is capable of being cured at low temperature while still maintaining superior barrier performance. This composition comprises (a) an aromatic compound having meta-substituted epoxy functionalities; (b) a multifunctional aliphatic amine; (c) optionally, one or more fillers; (d) optionally one or more adhesion promoters; (c) optionally, a phenolic cure accelerator.07-01-2010

Patent applications by Donald E. Herr, Doylestown, PA US

George Herr, Canton, MI US

Patent application numberDescriptionPublished
20080229602TEMPERATURE SENSITIVE DIPSTICK - A fluid level indicator for determining the level of fluid in a container includes a dipstick that is entered into the fluid in the container and withdrawn from the fluid, a billet of thermochromic material having a reference temperature, a billet length extending along a portion of the dipstick, and a fluid level range marking on the dipstick along the length of the billet.09-25-2008
20110306464Power-Off Downshift Engagement Dampening - A method for controlling a power-off downshift in a powershift transmission includes disengaging the current gear, synchronizing engine speed and a speed of the target gear layshaft by increasing a torque capacity of the target gear clutch, disengaging the clutch, engaging the target gear, and reengaging the clutch.12-15-2011

Hugh Herr, Somerville, MA US

Patent application numberDescriptionPublished
20120136459ACTIVE ANKLE FOOT ORTHOSIS - An Active Ankle Foot Orthosis (AAFO) is provided where the impedance of an orthotic joint is modulated throughout the walking cycle to treat ankle foot gait pathology, such as drop foot gait. During controlled plantar flexion, a biomimetic torsional spring control is applied where orthotic joint stiffness is actively adjusted to minimize forefoot collisions with the ground. Throughout late stance, joint impedance is minimized so as not to impede powered plantar flexion movements, and during the swing phase, a torsional spring-damper (PD) control lifts the foot to provide toe clearance. To assess the clinical effects of variable-impedance control, kinetic and kinematic gait data were collected on two drop foot participants wearing the AAFO. It has been found that actively adjusting joint impedance reduces the occurrence of slap foot, allows greater powered plantar flexion, and provides for less kinematic difference during swing when compared to normals.05-31-2012

Hugh Miller Herr, Somerville, MA US

Patent application numberDescriptionPublished
20100114329HYBRID TERRAIN-ADAPTIVE LOWER-EXTREMITY SYSTEMS - Hybrid terrain-adaptive lower-extremity apparatus and methods that perform in a variety of different situations by detecting the terrain that is being traversed, and adapting to the detected terrain. In some embodiments, the ability to control the apparatus for each of these situations builds upon five basic capabilities: (1) determining the activity being performed; (2) dynamically controlling the characteristics of the apparatus based on the activity that is being performed; (3) dynamically driving the apparatus based on the activity that is being performed; (4) determining terrain texture irregularities (e.g., how sticky is the terrain, how slippery is the terrain, is the terrain coarse or smooth, does the terrain have any obstructions, such as rocks) and (5) a mechanical design of the apparatus that can respond to the dynamic control and dynamic drive.05-06-2010

James Herr, San Jose, CA US

Patent application numberDescriptionPublished
20100225294INRUSH CURRENT CONTROL SYSTEM WITH SOFT START CIRCUIT AND METHOD - A method of and system for controlling the inrush current generated in a MOSFET of an inrush current control system, wherein the MOSFET includes a source, gate and drain. The dV/dt at the drain of the MOSFET is controlled so as to set the inrush current level as a function of dV/dt, independent of current limit without requiring a separate capacitor connected between the gate and drain of the MOSFET so that the MOSFET can turn on and off more quickly.09-09-2010

Jay Herr, Morgantown, PA US

Patent application numberDescriptionPublished
20120126595GLIDING ROCKING CHAIR AND OTTOMAN - A furniture system includes a chair and an ottoman. The chair, includes a seat, a seatback, first and second armrests, first and second base structures, and at least one chair linkage system. The seat moves relative to the first and second base structures according to the at least one linkage system. The chair includes a recess that stores the ottoman. The ottoman includes a top structure and at least one base structure. The top structure transitions between a first mode and a second mode. In the first mode, the top structure is positioned at a first angle relative to the at least one base structure and moves relative to the at least one base structure. In the second mode, the top structure is positioned at a second angle relative to the at least one base structure and remains fixed relative to the at least one base structure.05-24-2012

Jeremy C. Herr, Elkins Park, PA US

Patent application numberDescriptionPublished
20080320385Graphical Object Insertion During Preparation of Production Data for a Print Job Using a Still Image Proxy of a Page Description Language Image File - Production data is prepared for a print job wherein the production data includes an electronic document defined by a page description language (PDL). The electronic document is stored in a PDL image file. First, a still image proxy of the PDL image file is created, Next, one or more graphical objects are inserted into an image display of the still image proxy and properties of the inserted graphical objects are recorded. The recorded properties of the inserted graphical objects are then used to revise or rebuild the PDL image file so as to match the PDL image file to the inserted graphical objects.12-25-2008
20120075673Preparation of production data for a print job using a still image proxy of a page description language image file - An automated, computer-implemented method is provided for preparing production data for a print job. The production data includes an electronic document defined by a page description language (PDL). The electronic document is stored in a PDL image file. The production data for the print job is prepared via a processor. A still image proxy is created of the PDL image file. Information about electronic manipulations of an image display of the still image proxy is received and recorded. The information about the manipulations is used, via the processor, to revise the PDL image file so as to match the PDL image file to the manipulations made to the image display of the still image proxy, thereby preparing an edited PDL image file which is the electronic document for the print job.03-29-2012

Jeremy C. Herr, Jenkintown, PA US

Patent application numberDescriptionPublished
20100214612Computer program product for preparation of production data for a print job using a still image proxy of a page description language image file - A computer program product prepares production data for a print job. The production data includes an electronic document defined by a page description language (PDL). The electronic document is stored in a PDL image file. The production data for the print job is prepared via a processor. The computer program product has computer-readable media encoded with instructions for execution by the processor to create a still image proxy of the PDL image file, electronically manipulate an image display of the still image proxy and record information about the manipulations, and use the information about the manipulations to revise the PDL image file so as to match the PDL image file to the manipulations made to the image display of the still image proxy.08-26-2010

Patent applications by Jeremy C. Herr, Jenkintown, PA US

John Herr, Bellefonte, PA US

Patent application numberDescriptionPublished
20110252800ALUMINIUM COMBUSTION POWER SYSTEM - An engine that oxidizes aluminum with water to produce electrical and/or mechanical power. The engine can include a fuel made at least partly from aluminum powder that flows like liquid under high pressure. The engine can also include a steam supply system, a combustor, a fuel feed system, a fuel injection system, and a water supply system.10-20-2011

John C. Herr, Charlottesville, VA US

Patent application numberDescriptionPublished
20080274117Validation of Tssk Family Members and Tsks as Male Contraceptive Targets - The present invention relates to a family of testis specific kinases (the TSSK family) and a substrate (TSKS) of TSSK, nucleic acid sequences encoding those kinases and substrate, and antibodies and antagonists against the kinases and substrate, methods of regulating these proteins, and their use as contraceptive targets.11-06-2008
20080318250Compositions and Methods for Identifying Sperm for Forensic Applications - Methods and compositions for identifying and isolating sperm cells from samples containing multiple cell types are described. The methods and compositions employ antibodies that specifically bind to sperm-specific antigens located on or internal to the sperm plasma membrane. A reporter molecule may be conjugated to the antibodies to aid in the detection of sperm. The antibodies may be targeted to sperm-specific antigens in the head and/or tail of sperm to facilitate the identification and isolation of sperm cells from forensic samples prepared from sexual assault evidence. Purified DNA from the isolated sperm cells can be amplified by polymerase chain reaction to assist forensic analysis in sexual assault cases.12-25-2008
20090136962DIAGNOSTIC MARKERS FOR CANCER - The present invention provides compositions and methods useful for diagnosing cancer and for monitoring the progression and treatment of cancer, as well as targets for treating cancer. The invention provides sperm and testis associated antigens, such as the protein CABYR, as biomarkers and as targets for chemotherapy.05-28-2009
20090214552Novel Egg Receptors for Sperm Proteins - The present invention relates to novel egg membrane protein receptors and to methods of inhibiting the interaction of sperm proteins with egg proteins. The invention further relates to methods of preventing and inhibiting sperm-egg binding, sperm-egg fusion, and fertilization. The invention further relates to the egg membrane proteins MET and ZEP.08-27-2009
20100183617COMPOSITIONS AND METHODS FOR REGULATING SAS1R - The present invention provides compositions and methods useful for regulating fertilization and for use as a contraceptive based on the discovery herein of an oocyte specific protein, SAS1R (Sperm Acrosomal SLLP1 Receptor), which is a sperm protein receptor. Six SAS1R variants, including the full length SAS1R, were identified. mSLLP1 and SAS1R co-localized to oocytes and to acrosomes of acrosome-reacted sperm. Interactions between mSLLP1 and SAS1R were demonstrated by far-western analysis, in a yeast two-hybrid system under stringent selection conditions, and by immunoprecipitation of SAS1R by anti-mSLLP1 as well as the converse. Purified recombinant SAS1R was found to have protease activity, to inhibit fertilization in-vitro, and to induce an immune response in females. Together, the results suggest SAS1R is a proteolytically active, oocyte and early embryo specific oolemmal metalloprotease receptor for the sperm intra-acrosomal ligand SLLP1 and is a target for regulating fertilization and as a contraceptive.07-22-2010

Patent applications by John C. Herr, Charlottesville, VA US

Lawrence N. Herr, Coupland, TX US

Patent application numberDescriptionPublished
20080266994LEVEL DETECT CIRCUIT - A detect circuit may be used to detect one or more characteristics corresponding to the fuse being programmed. When the one or more characteristics of the fuse being programmed reach the desired states or values, the programming of the fuse is discontinued. Thus, the programming duration for each fuse is customized for each fuse. As a result, for some embodiments, there may be fewer fuses that have been over-programmed. In addition, for some embodiments, the range of impedances of the programmed fuses have a narrower distribution of impedances due to the use of the detect circuit.10-30-2008
20090075428ELECTROMAGNETIC SHIELD FORMATION FOR INTEGRATED CIRCUIT DIE PACKAGE - Electromagnetic shielding for an integrated circuit packaged device. The method includes forming shielding structures by forming openings in an encapsulated structure. The openings are filled with conductive material that surrounds at least one die. The encapsulated structure may include a plurality of integrated circuit die. A layered redistribution structure is formed on one side of the encapsulated structure.03-19-2009
20100027360INTEGRATED CIRCUIT HAVING AN ARRAY SUPPLY VOLTAGE CONTROL CIRCUIT - An integrated circuit comprises a plurality of memory cells and an array supply voltage control circuit. The plurality of memory cells are organized in rows and columns. A row comprises a word line and all of the memory cells coupled to the word line. A column comprises a bit line pair and all of the memory cells coupled to the bit line pair. The array supply voltage control circuit is coupled to the plurality of memory cells. The array supply voltage control circuit is for receiving a power supply voltage and for providing a reduced power supply voltage to memory cells of a selected column during a write operation in response to a voltage differential on the bit line pair of the selected column.02-04-2010
20100181629METHOD OF FORMING AN INTEGRATED CIRCUIT - A method includes forming a source, a drain, and a disposable gate (07-22-2010
20110003435ELECTROMAGNETIC SHIELD FORMATION FOR INTEGRATED CIRCUIT DIE PACKAGE - Electromagnetic shielding for an integrated circuit packaged device. The method includes forming shielding structures by forming openings in an encapsulated structure. The openings are filled with conductive material that surrounds at least one die. The encapsulated structure may include a plurality of integrated circuit die. A layered redistribution structure is formed on one side of the encapsulated structure.01-06-2011

Patent applications by Lawrence N. Herr, Coupland, TX US

Matthew E. Herr, Chandler, IN US

Michael D. Herr, Huntersville, NC US

Patent application numberDescriptionPublished
20090313156Adaptive daily spending limits - A computer-implemented system and method are provided for adapting the spending limit of a debit instrument in a networked computer system, particularly a daily spending limit. The method comprises determining or receiving notification of whether an electronic request to approve a debit instrument transaction was declined for exceeding a withdrawl limit or a spending limit, determining transactional risk associated with the debit instrument transaction using computer-implemented criteria, and adapting the spending limit of the debit instrument after the determination of transactional risk. Computer-implemented criteria are used to assess the transactional risk associated with a particular debit instrument transaction.12-17-2009

Ouentin P. Herr, Ellicott City, MD US

Patent application numberDescriptionPublished
20090322374METHOD AND APPARATUS FOR CONTROLLING QUBITS WITH SINGEL FLUX QUANTUM LOGIC - In one embodiment, the disclosure relates to a method and apparatus for controlling the energy state of a qubit by bringing the qubit into and out of resonance by coupling the qubit to a flux quantum logic gate. The qubit can be in resonance with a pump signal, with another qubit or with some quantum logic gate. In another embodiment, the disclosure relates to a method for controlling a qubit with RSFQ logic or through the interface between RSFQ and the qubit.12-31-2009

Richard D. Herr, Berkeley, CA US

Patent application numberDescriptionPublished
20090238383LOUDSPEAKER SYSTEM AND METHOD FOR PRODUCING SYNTHESIZED DIRECTIONAL SOUND BEAM - A loudspeaker system has a plurality of relatively small transducer elements configured in a closely spaced transducer array such that their acoustic outputs combine to produce a focused beam of sound in front of the array that is substantially uniform about the beams radiation axis. The transducer array lies in a plane and has a perimeter that approximates a circle, and will have fill-factor with respect to a circle circumscribing the array of at least approximately 70%. In one variation of the loudspeaker system, the transducer array is constructed in smaller transducer array modules that are operatively fitted together to produce a larger array.09-24-2009

Robert J. Herr, Voorheesville, NY US

Patent application numberDescriptionPublished
20120122837INHIBITORS OF FATTY ACID BINDING PROTEIN - The present invention relates to novel heterocyclic compounds as Fatty Acid Binding Protein (“FABP”) inhibitors, pharmaceutical compositions comprising the heterocyclic compounds and the use of the compounds for treating or preventing a cardiovascular disease, a metabolic disorder, obesity or an obesity-related disorder, diabetes, dyslipidemia, a diabetic complication, impaired glucose tolerance or impaired fasting glucose.05-17-2012

Robert Jason Herr, Voorheesville, NY US

Patent application numberDescriptionPublished
20080214448Compounds, Methods and Formulations for the Oral Delivery of a Glucagon-Like Peptide (Glp)-1 Compound or a Melanocortin-4 Receptor (Mc4) Agonist Peptide - The present invention relates to novel compounds, methods, and formulations useful for the oral delivery of a GLP-1 compound or an MC4 agonist peptide.09-04-2008
20090170861Pyridazinone Derivatives Useful as Glucan Synthase Inhibitors - In its many embodiments, the present invention provides -substituted pyridazinone compounds as glucan synthase inhibitors, methods of preparing such compounds, pharmaceutical including one or more of such compounds, methods of preparing pharmaceutical formulations including one or more such compounds or one or more such compounds along with other antifungal agents, and methods of treatment, prevention, inhibition, or amelioration of one or more fungal infections associated with glucan synthase using such compounds or pharmaceutical compositions.07-02-2009
20090239798Compounds, Methods and Formulations for the Oral Delivery of a Glucagon-Like Peptide (Glp)-1 Compound or a Melanocortin-4 Receptor (Mc4) Agonist Peptide - The present application relates to novel compounds, methods and formulations useful for the oral delivery of a glucagon like peptide-1 compound or a melanocortin 4 receptor agonist peptide.09-24-2009
20100120876COMPOUNDS, METHODS AND FORMULATIONS FOR THE ORAL DELIVERY OF A GLUCAGON-LIKE PEPTIDE (GLP-1) COMPOUND OR A MELANOCORTIN-4 RECEPTOR (MC4) AGONIST PEPTIDE - The present invention relates to novel compounds, methods, and formulations useful for the oral delivery of a GLP-1 compound or an MC4 agonist peptide.05-13-2010
20100204207Compounds and Methods for Treating Dyslipidemia - Compounds of Formula (I): wherein n, m, p, q, Y, R1, R2, R3a, R3b, R4, R5, and R6 are as defined herein and their pharmaceutical compositions and methods of use are disclosed.08-12-2010
20110190205Compounds, Methods and Formulations for the Oral Delivery of a Glucagon-Like Peptide (Glp)-1 Compound or a Melanocortin-4 Receptor (Mc4) Agonist Peptide - The present application relates to novel compounds, methods and formulations useful for the oral delivery of a glucagon like peptide-1 compound or a melanocortin 4 receptor agonist peptide.08-04-2011

Patent applications by Robert Jason Herr, Voorheesville, NY US

Robert Jason Herr, Voortheesville, NY US

Patent application numberDescriptionPublished
20110312995BRIDGED AND FUSED HETEROCYCLIC ANTIDIABETIC COMPOUNDS - This invention provides for certain bridged and fused heterocyclic compounds of the formula (I) or a pharmaceutically acceptable salt, ester solvate or prodrug thereof wherein: L is: (II) and the other variables are defined herein; the inventive compounds are agonists of the G-protein coupled receptor 40 (GPR40, also known as free fatty acid receptor FFAR). This invention further relates to pharmaceutical compositions containing these compounds, and the use of these compounds to regulate insulin levels in a mammal. The compounds may be used, for example in the prevention and treatment of Type 2 diabetes mellitus and in the prevention and treatment of conditions related to Type 2 diabetes mellitus, such as insulin resistance, obesity and lipid disorders.12-22-2011

Stefan Herr, Greenvilee, SC US

Patent application numberDescriptionPublished
20110135477Method and Apparatus for Increasing Lift on Wind Turbine Blade - A lift generating apparatus for a wind turbine rotor blade comprising a first sidewall and an opposing second sidewall coupled together at a leading edge and at a trailing edge. The lift generating apparatus includes at least one forward blade extension coupled to the rotor blade to define a first airflow channel between the forward blade extension and the rotor blade. The lift generating apparatus also includes at least one aft blade extension coupled to the rotor blade to define a second airflow channel between the aft blade extension and the rotor blade.06-09-2011

Stephen D. Herr, Richmond, VA US

Patent application numberDescriptionPublished
20110108064METHODS AND SYSTEMS FOR MOVEMENT OF AN AUTOMAIC CLEANING DEVICE USING VIDEO SIGNAL - A method of cleaning an area using an automatic cleaning device may include receiving, from a video camera, information associated with an edge located on a surface, determining, by an automatic cleaning device, a position of the automatic cleaning device on the surface relative to the edge and using the received information to move the automatic cleaning device from the determined position along a path so that the automatic cleaning device cleans the surface along the path. The path may be substantially parallel to the edge, and the edge may be located a distance from a reference point on the automatic cleaning device during movement of the automatic cleaning device.05-12-2011
20110112714METHODS AND SYSTEMS FOR MOVEMENT OF ROBOTIC DEVICE USING VIDEO SIGNAL - A method of navigating an area using a mobile robotic device may include receiving, from a video camera, information associated with an edge located on a surface, determining, by a mobile robotic device, a position of the mobile robotic device on the surface relative to the edge and using the received information to move the mobile robotic device from the determined position along a path. The path may be substantially parallel to the edge, and may be located a distance from a reference point on the mobile robotic device during movement of the mobile robotic device.05-12-2011

Vince Herr, Overland Park, KS US

Patent application numberDescriptionPublished
20110167903ROTARY POSITIVE DISPLACEMENT FLOWMETER - A rotary positive displacement flowmeter of the type utilizing two displacement rotors and a blocking rotor with the blocking rotor having a single recess and the displacement rotor cylinders being of substantially similar size as the blocking rotor, resulting in a uniform flowpath through the flowmeter with alignment of the rotor axes in a 180 degree plane.07-14-2011