| Patent application number | Description | Published |
|---|
| 20080200503 | Macrocylic Inhibitors Of Hepatitis C Virus - Inhibitors of HCV of formula (I). | 08-21-2008 |
| 20080214588 | Hiv Inhibiting 2-(4-Cyanophenyl)-6-Hydroxylaminopyrimidines - HIV replication inhibitors of formula (I) pharmaceutically acceptable addition salts; or stereochemically isomeric forms thereof, wherein R | 09-04-2008 |
| 20080214648 | Hiv Prodrugs Cleavable by Cd26 - The present invention provides new prodrugs which are conjugates of a therapeutic compound and a peptide wherein the conjugate is cleavable by dipeptidyl-peptidases, more preferably by CD26, also known as DPPIV (dipeptidyl aminodipeptidase IV). The present prodrugs have the formula | 09-04-2008 |
| 20080262058 | Macrocylic Inhibitors of Hepatitis C Virus - Inhibitors of HCV replication of formula (I) | 10-23-2008 |
| 20080269322 | Substituted Aminophenylsulfonamide Compounds as Hiv Protease Inhibitor - The present invention concerns substituted aminophenylsulfonamide compounds, their use as protease inhibitors, in particular as broad-spectrum HIV protease inhibitors, processes for their preparation as well as pharmaceutical compositions and diagnostic kits comprising them. The present invention also concerns combinations of the present substituted aminophenylsulfonamide compounds with another anti-retroviral agent. It further relates to their use in assays as reference compounds or as reagents. | 10-30-2008 |
| 20080287488 | Use of a Sulfonamide Compound For Improving the Pharmacokinetics of a Drug - A method for improving the pharmacokinetics of drugs, which are metabolized by cytochrome P450 monooxygenase is disclosed. More specifically it relates to a method for improving the pharmacokinetics of retroviral protease inhibitors and in particular for improving the pharmacokinetics of human immunodeficiency virus (HIV) protease inhibitors. A pharmaceutical composition and its use in the manufacture of a medicament for the inhibition or treatment of an HIV infection or AIDS in a human being are also part of the invention. | 11-20-2008 |
| 20080306061 | Aminophenylsulfonamide Derivatives as Hiv Protease Inhibitor - The present invention concerns substituted aminophenylsulfonamide compounds and derivatives, their use as protease inhibitors, in particular as broadspectrum HIV protease inhibitors, processes for their preparation as well as pharmaceutical compositions and diagnostic kits comprising them. The present invention also concerns combinations of the present substituted aminophenylsulfonamide compounds and derivatives with another anti-retroviral agent. It further relates to their use in assays as reference compounds or as reagents. | 12-11-2008 |
| 20090062311 | MACROCYLIC INHIBITORS OF HEPATITIS C VIRUS - Inhibitors of HCV replication of formula (I) | 03-05-2009 |
| 20090105302 | Macrocylic Inhibitors of Hepatitis C Virus - Inhibitors of HCV replication of formula (I) | 04-23-2009 |
| 20090118312 | Macrocylic Inhibitors of Hepatitis C Virus - Compounds of the formula I: | 05-07-2009 |
| 20090203743 | SMALL MOLECULE ENTRY INHIBITORS - The present invention concerns the compounds having the formula | 08-13-2009 |
| 20090247512 | MACROCYLIC INHIBITORS OF HEPATITIS C VIRUS - Inhibitors of HCV replication of formula (I) | 10-01-2009 |
| 20090281140 | Macrocyclic inhibitors of hepatitis c virus - Inhibitors of HCV replication of formula (I) | 11-12-2009 |
| 20090281141 | MACROCYCLIC INHIBITORS OF HEPATITIS C VIRUS - Inhibitors of HCV replication of formula (I) | 11-12-2009 |
| 20100022578 | MACROCYCLIC INHIBITORS OF HEPATITIS C VIRUS - Inhibitors of HCV replication of formula (I) | 01-28-2010 |
| 20100029632 | BROADSPECTRUM 2-AMINO-BENZOXAZOLE SULFONAMIDE HIV PROTEASE INHIBITORS - The present invention concerns the compounds having the formula | 02-04-2010 |
| 20100121060 | HIV INHIBITING 2-(4-CYANOPHENYL)-6-HYDROXYLAMINOPYRIMIDINES - HIV replication inhibitors of formula | 05-13-2010 |
| 20100240698 | MACROCYCLIC INHIBITORS OF HEPATITIS C VIRUS - Inhibitors of HCV of formula al | 09-23-2010 |
| 20110160468 | PROCESS FOR THE PREPARATION OF (3R,3AS,6AR)-HEXAHYDROFURO [2,3-B] FURAN-3-YL (1S,2R)-3-[[(4-AMINOPHENYL) SULFONYL] (ISOBUTYL) AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE - The present invention relates to a process for the preparation of (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl(1S,2R)-3-[[(4-aminophenyl)sulfonyl](isobutyl)amino]-1-benzyl-2-hydroxypropylcarbamate as well as novel intermediates for use in said process. (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl(1S,2R)-3-[[(4-aminophenyl)sulfonyl](isobutyl)amino]-1-benzyl-2-hydroxypropylcarbamate is particularly useful as an HIV protease inhibitor. | 06-30-2011 |
