Henry, GB
Adam David Henry, Cottingham GB
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20140142352 | BUTANOL PURIFICATION - Provided herein are processes for adjusting a fermentation medium to reduce the activity of one or more carboxylic acids. The processes comprise (a) providing a recombinant microorganism comprising an engineered butanol biosynthetic pathway, (b) contacting the recombinant microorganism with a fermentation medium whereby butanol is produced and wherein the fermentation medium comprises one or more carboxylic acids, and (c) adjusting the fermentation medium to reduce the activity of the one or more carboxylic acids. Also provided are processes for reducing the activity of one or more carboxylic acids in a feed. The processes comprise (a) providing a feed from a fermentation vessel, wherein the feed comprises a composition produced by a recombinant microorganism comprising an engineered butanol biosynthetic pathway, wherein the composition comprises butanol, water, and one or more carboxylic acids; and (b) adjusting the feed, wherein adjusting the feed reduces the activity of the one or more carboxylic acids. | 05-22-2014 |
Alastair James Henry, Middlesex GB
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20100036091 | ANTIBODY-BASED DIAGNOSTICS AND THERAPEUTICS - Compositions and methods relating to sclerostin binding agents, such as antibodies and polypeptides capable of binding to sclerostin, are provided. | 02-11-2010 |
Alistair J. Henry, Middlesex GB
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20110097342 | BINDING AGENTS - Compositions and methods relating to epitopes of sclerostin protein, and sclerostin binding agents, such as antibodies capable of binding to sclerostin, are provided. | 04-28-2011 |
20110305702 | EPITOPES - Compositions and methods relating to epitopes of sclerostin protein, and sclerostin binding agents, such as antibodies capable of binding to sclerostin, are provided. | 12-15-2011 |
Alistair James Henry, Slough GB
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20150219635 | Method for Identifying Compounds of Therapeutic Interest - The present invention relates to an improved method for drug discovery. In particular the present invention provides a method of identifying compounds capable of binding to a functional conformational state of a protein of interest or protein fragment thereof, said method comprising the steps of: (a) Binding a function-modifying antibody to the target protein of interest or a fragment thereof to provide an antibody-constrained protein or fragment, wherein the antibody has binding kinetics with the protein or fragment which are such that it has a low dissociation rate constant, (b) Providing a test compound which has a low molecular weight, (c) Evaluating whether the test compound of step b) binds the antibody constrained protein or fragment, and (d) Select a compound from step c) based on the ability to bind to the protein or fragment thereof. | 08-06-2015 |
Alistair James Henry, Middlesex GB
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20090304713 | BINDING AGENTS - Compositions and methods relating to epitopes of sclerostin protein, and sclerostin binding agents, such as antibodies capable of binding to sclerostin, are provided. | 12-10-2009 |
20130203968 | ANTIBODY-BASED DIAGNOSTICS AND THERAPEUTICS - Compositions and methods relating to sclerostin binding agents, such as antibodies and polypeptides capable of binding to sclerostin, are provided. | 08-08-2013 |
Alistair James Henry, Berkshire GB
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20110262443 | Epitopes Of Il-17a And Il-17f And Antibodies Specific Thereto - The present invention relates neutralising epitopes of IL-17A and IL-17F and antibodies which bind those epitopes. The present invention also relates to the therapeutic uses of the antibody molecules and methods for producing them. | 10-27-2011 |
Alistar James Henry, Slough GB
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20140193403 | Epitopes of IL-17A and IL-17F and Antibodies Specific Thereto - The present invention relates neutralising epitopes of IL-17A and IL-17F and antibodies which bind those epitopes. The present invention also relates to the therapeutic uses of the antibody molecules and methods for producing them. | 07-10-2014 |
20150315272 | Epitopes of IL-17A and IL-17F And Antibodies Specific Thereto - The present invention relates neutralising epitopes of IL-17A and IL-17F and antibodies which bind those epitopes. The present invention also relates to the therapeutic uses of the antibody molecules and methods for producing them. | 11-05-2015 |
Andrew H. Henry, Ely GB
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20090094715 | METHODS OF USE OF ANTIBODIES WITH REDUCED IMMUNOGENICITY OR TOXICITY - Humanized antibodies which bind the NR-LU-13 antigen, conjugates containing such antibodies, and their use in pretargeting methods and conventional antibody therapy and immunodiagnosis are provided. | 04-09-2009 |
Christiani Jeya Kumar Henry, Oxford GB
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20110293816 | PRODUCT TO REDUCE GLYCEMIC RESPONSE OF CARBOHYDRATE BASED FOODS - The invention relates to the use of flour containing a mixture of pulverized edible parts of Okra plant species, | 12-01-2011 |
20130189411 | METHOD FOR PROCESSING FOOD PRODUCT AND FOOD PRODUCT THEREOF - The invention relates to a method for processing at least one food product. For example, the invention relates to a process of preparing cooked food products, for example fried food products with reduced oil content. A two-step process is performed on the food product before cooking or frying. The food product is first contacted with a first composition comprising at least one divalent cation (e.g. Ca2+ and/or Mg2+) and at least one acid (e.g. carboxylic acid). After removing from the first composition, the food product is contacted with a second composition comprising okra, a part thereof, or an extract thereof, and at least one hydrocolloid. The invention also relates to the compositions used as well as to the food product or at least one such fried food product with reduced oil content. | 07-25-2013 |
20130295266 | REDUCED SODIUM COMPOSITION - The present invention provides a reduced sodium composition comprising at least one potassium salt, at least one sodium salt, at least one emulsifier and at least one thickening agent. For example, the reduced sodium composition comprises at least: one potassium salt, at least one sodium salt, glycerol monostearate and maltodextrin as well as to its method of preparation. The reduced sodium composition is used for enhancing the flavour of food, as a food seasoning, food condiment and/or food additive and provides a healthier alternative to the consumer, in particular where reducing the sodium in the diet is beneficial for health. | 11-07-2013 |
David Henry, Edinburgh GB
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20150062530 | APPARATUS AND METHOD FOR RETINAL MEASUREMENT - Embodiments of the present invention provide a retinal densitometer, comprising an illumination unit for outputting bleaching illumination for photo-bleaching an eye and reflectance illumination at one or more wavelengths for determining reflectance of the eye at the one or more wavelengths, an imaging device arranged to output image data corresponding to an image of the eye at the one or more wavelengths of reflectance illumination, and a control unit arranged to control the illumination unit and the imaging device to output the bleaching illumination, the reflectance illumination at the one or more wavelengths and to output image data according to a predetermined sequence. | 03-05-2015 |
Dean Henry, Birmingham GB
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20090222359 | Stock Monitoring - System(s) and method(s) for stock monitoring are provided. Stock monitoring system(s) may include e.g., a housings one or more doors disposed in or on the housing, a sensor for sensing the condition of the door(s) and providing a door closed signal indicative of the door(s) having been closed by a user; one or more containers for stock items, located within the housing, the or each container having associated therewith a weight sensor for providing a weight signal indicative of the current weight of the container, and control circuitry, coupled for communication with the weight sensor(s). Method(s) may include, e.g., receiving a door closed signal; receiving one or more weight signals; and determining, for the or each container, the number of stock items removed from the container(s) by the user, from the weight signal(s) occurring during a predetermined sensing period, the predetermined sensing period being dependent upon the door closed signal. | 09-03-2009 |
20100282840 | STOCK MONITORING - System(s) and method(s) for stock monitoring are provided. Stock monitoring system(s) may include, e.g., a housing, one or more doors disposed in or on the housing, a sensor for sensing the condition of the door(s) and providing a door closed signal indicative of the door(s) having been closed by a user; one or more containers for stock items, located within the housing, the or each container having associated therewith a weight sensor for providing a weight signal indicative of the current weight of the container, and control circuitry, coupled for communication with the weight sensor(s). Method(s) may include, e.g., receiving a door closed signal; receiving one or more weight signals; and determining, for the or each container, the number of stock items removed from the container(s) by the user, from the weight signal(s) occurring during a predetermined sensing period, the predetermined sensing period being dependent upon the door closed signal. | 11-11-2010 |
Dean Charles Henry, Solihull GB
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20160071052 | STOCK MONITORING - A stock monitoring system, for monitoring items of stock in one or more storerooms for stock items. The system includes a portable device (e.g. PDA), the portable device including a first processor and, coupled thereto, a first wireless transceiver for short-range communication, the portable device being adapted to receive user inputs from a first user. A second wireless transceiver is coupled to the first processor, the second wireless transceiver being adapted for long-range wireless communications (e.g. 3G) with a remote system. The first processor is operable for receiving a user ID of a second user, and receiving one or more further inputs, at least a first input being received via the first wireless transceiver and including item data corresponding to an item, and at least a second user input being from the first user and associating the item with the second user. The first processor is operable for transmitting to the remote system via the second wireless transceiver, at least the item data, associated with the user ID. The system may further comprising an intermediate unit, the intermediate unit including a second processor and, coupled thereto, a reader and a wireless transmitter, the reader and/or wireless transmitter being adapted for short-range communication. The second processor may be operable, upon reading the user ID from an ID card of the second user by the reader, for transmitting the user ID user via the wireless transmitter, e.g. for a predetermined period. The first processor may be operable for receiving a user ID of a second user via the first wireless transceiver. Receiving the first input may comprises receiving the item data following placing of the portable device in the vicinity of a tag, the tag being mounted on or associated with the item and embodying encoded item data corresponding to the item. The reader, wireless transmitter and/or the first wireless transceiver may comprise a near field communication (NFC) device, and the tag may comprise a NFC RFID tag. A method, portable device and intermediate unit are also disclosed. | 03-10-2016 |
Frank Henry, London GB
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20150374183 | TOILET BRUSH - The toilet brush includes a handle and a brush head, wherein the brush head is detachably connectable to the handle and includes bristles that are soluble or disintegrable in water. | 12-31-2015 |
Manus Henry, Oxford GB
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20120137754 | Determining Concentrations of Components of a Mixture - Systems and methods for determining concentrations of components of a multiphase fluid. A first flowmeter receives a fluid flow and generates measurements of the fluid flow. After at least partially separating the fluid flow into mixtures of its components, second and third flowmeters generate measurements of the mixtures. A data processing apparatus operatively coupled to the flowmeters receives the measurements and determines concentrations of the components of the fluid flow. In an embodiment, the measurements are mass flow and density readings. | 06-07-2012 |
Matthew Henry, Sussex GB
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20160105745 | ACOUSTIC APPARATUS AND OPERATION - A portable acoustic warning device which projects a specific acoustic waveform towards a target, creating a narrow beam of sound that is highly selective, minimising exposure to users and bystanders, whilst enabling a controlled dosage of sound to be applied to the target. The design of the device is tailored to this waveform thus achieving a very high degree of directivity. It is not intended for communicating verbal messages. This waveform achieves maximum intensity at the target whilst using a relatively low sound pressure level; meaning that the exposure levels can be controlled to ensure they are within existing health and safety legislation. A laser range finder limits the sound level at the target to a pre-determined level. An integrated camera is used to aid aiming. Video footage is recorded with use; along with the sound level at the target, exposure duration, time, date and GPS coordinates. | 04-14-2016 |
Nicholas J. Henry, Woodford Halse Northamptonshire GB
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20150083735 | COMPOSITE MATERIALS - A composite material comprises of at least first and second layers, each comprising a polymeric matrix material and wound tows for reinforcement. The tows are wound in opposite directions in each of the first and second layers such that overlapping tows form crossover regions. The wound tows in the second layer are arranged such that the crossover regions are formed to be laterally offset from the crossover regions in the first layer. | 03-26-2015 |
Sean Henry, Warwickshire GB
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20110123182 | EXPOSURE AND WHITE BALANCE OF PHOTOGRAPHIC DIGITAL CAMERAS - A target is provided for setting the exposure and white balance of a photographic digital camera. The target comprises a target surface that has a pre-determined reflectance for all wavelengths of visible light, and the target surface is provided with a target feature upon which the camera is able to focus while the target surface entirely fills a viewfinder of the camera. | 05-26-2011 |
Sean Justin Blair Henry, Warwickshire GB
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20110170276 | PHOTOGRAPHIC LIGHTING APPARATUS - A photographic lighting apparatus is adapted to rest upon a support surface, and comprises an operative panel having a light reflective and/or light transmissive wall, and a support member which supports the operative panel in an inclined orientation relative to the support surface. Such photographic lighting apparatus may be used as a light reflector or a light diffuser and is of particular utility for lighting the subject of a photograph from below. | 07-14-2011 |
Stephen Henry, Barrow-In-Furness GB
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20110155459 | CONNECTION SYSTEM AND METHOD FOR SUBSEA CABLES IN SEVERE ENVIRONMENTS - A technique facilitates the reliable connection of cables in subsea environments. A cablehead system is designed to reliably connect cables to subsea components while providing long term protection of the connection in potentially harsh, subsea environments. The cablehead system comprises a cable clamp housing which may be coupled to a bulkhead assembly by a cavity housing which provides space for routing of internal communication lines. One or more additional protective components are incorporated into the cablehead system to ensure a reliable connection and to further protect the internal communication lines from exposure to the surrounding environment. | 06-30-2011 |
Steven Henry, Darwen GB
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20080214730 | Solid Pigment Concentrates - Solid pigment concentrate comprising at least one pigment and a dispersant comprising a polyamine backbone and one or more hydrophobic pendent groups, characterized in that the concentrate further comprises a non-ionic 5 surface active agent comprising polyoxyalkylene groups. The polyamine backbone can for instance comprise polyalkylene imine building blocks. | 09-04-2008 |
Theodore B. Henry, Plymouth GB
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20130031644 | AUTONOMOUS LUX REPORTER SYSTEM AND METHODS OF USE - Disclosed are systems for expression of an autonomous lux reporter system in a vertebrate cell, such as mammalian or fish cell. In some examples the lux reporter system is operably connected to a pollutant-inducible DNA response element. Also disclosed are transgenic zebrafish, carrying pollution-inducible response elements, and methods of using such zebrafish to monitor pollutants. | 01-31-2013 |
William Henry, London GB
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20150057249 | Vesicular Formulations - The present invention relates to vesicular formulations for the treatment of rosacea. It also relates to a method of treating rosacea comprising administering a vesicular formulation according to the invention. | 02-26-2015 |
20150086524 | OPTIMISED SUBCUTANEOUS THERAPEUTIC AGENTS - Methods and dosage formulations are provided for subcutaneous administration in which therapeutic agents are modified to increase the hydrophilicity and molecular dimensions in relation to the native state of the therapeutic agent, in which the Cmax:Caverage ratio is lower than the Cmax:Caverage ratio of the agent when delivered intravenously. | 03-26-2015 |
20150125407 | Vesicular Formulations, Uses and Methods - The present invention relates to vesicular formulations for use in the topical administration of a biologically active agent, methods of administering a biologically active agent, a combined preparation comprising a vesicular formulation and a kit comprising a vesicular formulation. | 05-07-2015 |
20150132349 | Vesicular Formulations, Kits and Uses - The present invention relates to compositions containing vesicular formulations, kits, methods of preparation thereof or uses thereof. The present invention provides improved combinations of formulations, for topical use. | 05-14-2015 |
William Henry, Trumpington GB
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20110277870 | NEEDLELESS INJECTOR DRUG CAPSULE AND A METHOD FOR FILLING THEREOF - A method for tilling needleless injector capsules with liquid drug, whereby dissolved gas within the drug is replaced by a less soluble gas in order to reduce the inclusion of gas bubbles, or to prevent the growth of bubbles during storage and thereby prevent breakage of the capsules. | 11-17-2011 |
20120253273 | NEEDLELESS INJECTOR DRUG CAPSULE AND A METHOD FOR FILLING THEREOF - A method for tilling needleless injector capsules with liquid drug, whereby dissolved gas within the drug is replaced by a less soluble gas in order to reduce the inclusion of gas bubbles, or to prevent the growth of bubbles during storage and thereby prevent breakage of the capsules. | 10-04-2012 |
William Henry, County Bucks GB
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20120100171 | HAPTEN-CARRIER CONJUGATES WITH BACTERIAL TOXINS HAVING A SIGNAL PEPTIDE AS CARRIER AND THEIR USE IN IMMUNOGENIC COMPOSITIONS - This invention relates to immunogenic compositions for inducing an immune response against an antigen of interest. In particular, the invention provides immunogenic compositions comprising an antigen-carrier conjugate, wherein the carrier is a bacterial toxin that contains a signal peptide. The invention also provides methods of generating immunogenic compositions with enhanced immunogenicity, comprising adding a signal peptide to the bacterial carrier in an antigen-carrier conjugate, such as a hapten-carrier conjugate. The invention also provides methods for inducing an immune response to a hapten in a subject using these immunogenic compositions. | 04-26-2012 |
William Henry, Cambridge GB
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20130338578 | NEEDLELESS INJECTOR DRUG CAPSULE AND A METHOD FOR FILLING THEREOF - A method for tilling needleless injector capsules with liquid drug, whereby dissolved gas within the drug is replaced by a less soluble gas in order to reduce the inclusion of gas bubbles, or to prevent the growth of bubbles during storage and thereby prevent breakage of the capsules. | 12-19-2013 |
William Henry, Haddenham GB
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20100197621 | METHODS OF REDUCING THE PROLIFERATION AND VIABILITY OF MICROBIAL AGENTS - The invention relates to formulations of an antimicrobial agent, a lipid, and optionally a surfactant, and uses thereof for reducing the proliferation and viability of microbial agents. | 08-05-2010 |
20100249027 | CRF CONJUGATES WITH EXTENDED HALF-LIVES - The present invention relates to conjugates of CRF that have been modified to include a moiety that protects CRF from degradation and prolongs the half-life of CRF. The CRF conjugates of the invention have an increased half-life which results in a dose-sparing effect and less frequent administration | 09-30-2010 |
20110183906 | FACTOR IX CONJUGATES WITH EXTENDED HALF-LIVES - The present invention relates to conjugates of Factor IX that have been modified to include a biocompatible polymer moiety. The Factor IX conjugates are substantially free of contamination by Factor IXa. The Factor IX conjugates have improved pharmacokinetic properties, such as increased half-life, which results in dose sparing and less frequent administration. | 07-28-2011 |
20120232034 | VESICULAR FORMULATIONS - Disclosed herein are vesicular formulations that include one or more phospholipids and one or more surfactants and in certain embodiments the use of such formulations for the delivery of fatty acids for the treatment of disorders such as, fatty acid metabolic disorders, including essential fatty acid deficiency; pain or inflammation or osteoarthritis, more specifically for the treatment of deep tissue pain; asthma, bronchospasm, atherothrombatic cardiovascular disorders, avenous thrombatic disorders, inflammatory dermatoses disorders (e.g., atopic eczema, dishydrotic hand eczema, plaque type psoriasis, seborrheic eczema, and acne vulgaris), and dysmenorrhea. | 09-13-2012 |
20120245107 | METHODS OF REDUCING THE PROLIFERATION AND VIABLILITY OF MICROBIAL AGENTS - The invention relates to formulations of an antimicrobial agent, a lipid, and optionally a surfactant, and uses thereof for reducing the proliferation and viability of microbial agents. | 09-27-2012 |
20130129698 | CONJUGATED BLOOD COAGULATION FACTOR VIIA - The present invention provides a biocompatible polymer conjugated to FVIIa via one or more cysteine residues, suitably via a linker across a reduced disulphide bond in FVIIa, and pharmaceutical compositions comprising such conjugated forms of FVIIa. | 05-23-2013 |
20130150302 | CONJUGATED BLOOD COAGULATION FACTOR VIII - The present invention provides a biocompatible polymer conjugated to FVIII via one or more cysteine residues, suitably via a linker across a reduced disulphide bond in FVIII, and pharmaceutical compositions comprising such conjugated forms of FVIII. | 06-13-2013 |
20140100191 | Vesicular Formulations - Disclosed herein are vesicular formulations that include one or more phospholipids and one or more surfactants and in certain embodiments the use of such formulations for the delivery of fatty acids for the treatment of disorders such as, fatty acid metabolic disorders, including essential fatty acid deficiency; pain or inflammation or osteoarthritis, more specifically for the treatment of deep tissue pain; asthma, bronchospasm, atherothrombatic cardiovascular disorders, avenous thrombatic disorders, inflammatory dermatoses disorders (e.g., atopic eczema, dishydrotic hand eczema, plaque type psoriasis, seborrheic eczema, and acne vulgaris), and dysmenorrhea. | 04-10-2014 |