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Helenius
Ari Helenius, Zurich CH
| Patent application number | Description | Published |
|---|---|---|
| 20100272706 | ANTIVIRALS - This invention provides methods for inhibiting or treating infection by viruses, in particular pox viruses by modulating a kinase, in particular by inhibiting a host cell kinase, involved in mediating viral infection. Methods to identify, validate, and classify the cellular proteins required by viruses during infection of host cells in order to select agents which can inhibit viral infection are described herein. Using a systems biology approach the virus/host cell interaction is studied from initial attachment of the incoming virus to the cell surface, to entry, transcription, replication, biosynthesis, and assembly of progeny particles. The method employs a siRNA screening platform and uses gene silencing to map the ‘viral infectome’—a compilation of cellular proteins that the virus needs to establish infection and drive the infectious cycle. Charting the infectome provides information on the viral biology by the identification of host cell proteins involved in viral infection and allows the development of novel anti-viral drugs that prevent the viruses from establishing productive infection in cells. | 10-28-2010 |
David Helenius, Leominster, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100221380 | Expandable cavity for injection molding tool - An injection molding tool having a first section moveable with respect to a second section. In a first position, the first section contacts the second section along a parting line and forms a cavity. An expandable cavity part is moveably mounted with respect to the second section. In a closed condition, the expandable cavity part is in a retracted or molding position. The expandable cavity part can be moved away from the molding position or the closed condition to a release position or an expanded condition with allows access to molded part or other article. A core pin is either moveably mounted with respect to the expandable cavity part or is in a fixed position with respect to the expandable cavity part. | 09-02-2010 |
| 20100323051 | Lock for core assembly for injection molding tool - An injection molding tool having a core assembly with a shaft that is lockably or securedly mounted within a bore of a plate or within another suitable lock element. Rotational or other suitable movement of the lock results in or translates into axial movement of and/or axial forces apply to the core assembly. A guide ring assembly has a center ring with a non-circular bore and a correspondingly shaped core assembly, to prevent rotational movement of the core assembly with respect to the guide ring assembly. | 12-23-2010 |
Jonne Helenius, Dresden DE
| Patent application number | Description | Published |
|---|---|---|
| 20110207214 | NOVEL TOOLS FOR THE PRODUCTION OF GLYCOSYLATED PROTEINS IN HOST CELLS - The invention improves glycoprotein production and protein glycosylation engineering in eukaryotes, specifically the production of human-like complex or hybrid glycosylated proteins in lower eukaryotes such as yeasts. The invention provides glycosylation modified eukaryotic host cells capable of producing glycosylation optimized proteins useful as immunoglobulins and other therapeutic proteins, and provides cells capable of producing glycoproteins having glycan structures similar to glycoproteins produced in human cell. The invention further provides proteins with human-like glycan structures and novel compositions thereof producible by these cells. | 08-25-2011 |
Juha Helenius, Pori FI
| Patent application number | Description | Published |
|---|---|---|
| 20100135850 | AIR DISINFECTION DEVICE - A dry disinfection device comprising at least a process chamber ( | 06-03-2010 |
Kalle Helenius, Lieto As. FI
| Patent application number | Description | Published |
|---|---|---|
| 20110061968 | Sound Attenuator for Low Frequencies, Method for Manufacturing Sound Attenuator for Low Frequencies and System for Attenuating Low Frequencies for Example In Air-Conditioning Ducts of Paper Mills - A sound attenuator for low frequencies in an air-conditioning duct of paper mills includes a sound attenuator frame insertable in the air-conditioning duct. At least one attenuator member operating according to the plate resonator principle has a first resonator plate, a framework, whereto the first resonator plate is attached by its inner surface, and a second plate, which is essentially parallel to the first resonator plate. The second plate is attached to the framework by its inner surface, whereby the second plate, the framework and the first resonator plate delimit at least one attenuator unit. The first resonator plate, attached to the framework, is a steel plate and is attached to the framework by laser welding and the framework comprises a pressure balancing opening. | 03-17-2011 |
Mauri Helenius, Helsinki FI
| Patent application number | Description | Published |
|---|---|---|
| 20110174348 | AUTOMATED HAND-WASHING DEVICE - An automated hand-washing device includes a case-like housing having two openings (A), into which the user can introduce the hands for disinfection and automated spraying of an antispetic solution operating without hand contact through spray nozzles, from where the antispetic solution jet is directed precisely to the correct spot; the fingertips, the fingers and part of the palm. The openings (A) are oval, vertically elongated ellipses and they contain substantially equally shaped recesses, which urge the hands into the correct position for the period of disinfection. | 07-21-2011 |