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Heike

Heike Barlag, Nurnberg DE

Patent application numberDescriptionPublished
20090130658Arrangement for integrated and automated dna or protein analysis in a single-use cartridge, method for producing such a cartridge and operating method for dna or protein analysis using such a cartridge - A cartridge (card) having a system of microchannels and/or microcavities is used for automated DNA or protein analysis. In at least one embodiment, the microchannels or microcavities include geometrical structures for receiving dry reagents. For the purpose of industrial production, the cartridge is produced from a flat card support, e.g., by injection moulding. The reagents are spotted into the open channels, dried and then the channels are sealed by way of a film. A finished cartridge can thus be provided with a test sample and the fully automated measuring sequence can be initiated by inserting said cartridge into a read-out device.05-21-2009
20100155263METHOD AND SYTEM FOR DETERMINING THE CONCENTRATION OF AN ANALYTE/ENZUME COMPLEX OR OF AN ANALYTE/ENZYME CONJUGATE, ESPECIALLY FOR THE ELECTROCHEMICAL DETECTION OF THE ANALYTE, AND CORRESPONDING MEASURING DEVICE - A method follow the change in concentration of a redox-active substance, whereby suitable potentials for a reduction process or an oxidation process are applied to the working electrode of a measuring device. The potential of the working electrode is pulsed and measuring phases and relaxation phases are alternately produced, the pulse lengths of measuring phase and relaxation phase being determined in a suitable manner. A rapid relaxation of the concentration gradient is electrochemically forced so that the measurement can be carried out on simple transducer arrays. A device for carrying out the method includes a transducer array in addition to a suitable potentiostat. The transducer array can be formed of a planar metal substrate on which at least one flexible insulator is disposed, the metal surface and the insulator surface being firmly linked. The transducer array can also be formed of silicone-based CMOS structures.06-24-2010

Patent applications by Heike Barlag, Nurnberg DE

Heike Barlag, Nuremberg DE

Patent application numberDescriptionPublished
20080283397Electrochemical Transducer Array and Use Thereof - Electrochemical transducer arrays are already known from the prior art. According to the invention, the transducer array is provided with at least one flexible, planar metal substrate on which at least one flexible insulator having a firm connection between the metal surface and the insulator surface is disposed. The metal substrate and the insulator disposed thereon are structured in such a manner as to give metal areas which are electrically insulated the one from the other and which serve as sensor areas. The metal substrate used is self-contained so that the structured metal areas can be contacted from the lower side.11-20-2008
20090136922Method for carrying out an electrochemical measurement on a liquid measuring sample in a measuring chamber that can be accessed by lines, and corresponding arrangement - Especially in order to carry out the so-called enzyme-coupled DNA hybridisation test in a closed cartridge including a microfluid system, using stored dry reagents, the reagents must be dissolved in the microfluid system and transported into the measuring chamber directly before the measurement. During the dissolution of the reagents in water, air cushions that cannot reach the measuring chamber must absolutely be prevented from forming upstream of the reagent liquid. According to an embodiment of the invention, the liquid measuring sample and the liquid reagents are transported in such a way that the air cushion is directed into the waste line and the measuring sample and the reagents are then introduced into the measuring chamber without any air bubbles. In this way, measuring errors can be avoided.05-28-2009

Heike Bartsch De Torres, Ilmenau DE

Patent application numberDescriptionPublished
20100254099SILICON-CERAMIC COMPOSITE SUBSTRATE - The invention relates to a silicon-ceramic composite substrate (10-07-2010

Heike Becker, Mannheim DE

Patent application numberDescriptionPublished
20080242577Clear Rinsing Agent Containing Hydrophobically Modified Polycarboxylates - Rinse agent formulations for machine dishwashing, comprising as components: 10-02-2008
20080257190Use of Polymers Comprising Amino Groups Modified by Acid Groups for Producing Humidifying Agents or Humidifying Agent Concentrates, in Addition to Humidifying Agent Circuits for Offset Printing - The use of polymers which comprise amino groups modified with acid groups for the preparation of fountain solutions for offset printing. A process for printing by means of the offset technique, in which a fountain solution which comprises polymer which comprises amino groups modified with acid groups is used.10-23-2008
20090297884Use of hydrophobins for the surface treatment of hardened mineral building materials, natural stone, artificial stone and ceramics - Use of hydrophobins for treating the surface of cured mineral building materials, natural stone, cast stone or ceramic, a process for treating such surfaces and also surfaces of cured mineral building materials, natural stone, cast stone or ceramic that have a coating comprising hydrophobins.12-03-2009
20090305930Use of hydrophobin for hard surface soil-repellent treatment - Use of hydrophobins for soil-repellent treatment of hard surfaces, in particular in combination with a cleansing of the surface, processes for soil-repellent treatment of hard surfaces, cleansing agents for hard surfaces and also hard surfaces with a soil-repellent coating comprising hydrophobins.12-10-2009
20100004154THERMALLY SENSITIVE POLYMERIC DYE TRANSFER INHIBITOR - The invention relates to the use of thermally sensitive polymers as dye transfer inhibitors. The invention also relates to novel thermally sensitive polymers suitable as dye transfer inhibitors, and to washing compositions which comprise these polymers.01-07-2010
20100017973HYDROPHOBICALLY MODIFIED POLYALKYLENIMINES FOR USE AS DYE TRANSFER INHIBITORS - The invention relates to the use of hydrophobically modified polyalkylenimines as dye transfer inhibitors.01-28-2010

Patent applications by Heike Becker, Mannheim DE

Heike Blasko-Begoihn, Essen DE

Patent application numberDescriptionPublished
20110052522COSMETICS COMPRISING CISTUS PLANT EXTRACTS - The present invention relates to the use of an extract from 03-03-2011

Heike Brücher, Rathsweiler DE

Patent application numberDescriptionPublished
20110048509COMPOSITE EDGE FOR PRODUCING DOUBLE OR MULTIPLE PANE INSULATION GLASS OR SOLAR MODULES - This invention relates to an edge seal for manufacturing two-pane or multi-pane insulating glass or solar modules, there being provided a primary sealant and a secondary sealant.03-03-2011

Heike Brüser, Speyer DE

Patent application numberDescriptionPublished
20100310644ANTI-DANDRUFF COMPOSITIONS CONTAINING PEPTIDES - The present invention relates to the use of special peptides in composition which can be used in particular in hair and skin cosmetics, and to such peptide-containing compositions. In particular, the present invention relates to the use of such peptides as active ingredient for inhibition or treatment of dandruff which does not accumulate in the body or in the environment. Furthermore, the invention relates to the production of such compositions, to the peptides used themselves, to their production and to coding nucleotide sequences for such peptides, to dispensing systems for such peptides and to screening methods for identifying suitable further peptides.12-09-2010

Heike Dinter-Heidorn, Hannover DE

Patent application numberDescriptionPublished
20090263479FORMULATIONS FOR POORLY PERMEABLE ACTIVE PHARMACEUTICAL INGREDIENTS - The present invention relates to a pharmaceutical oral dosage form containing a poorly permeable active pharmaceutical ingredient and at least one permeability improving substance, wherein the permeability improving substance is thermostably embedded in a water-soluble matrix of a water soluble carrier, and to thermostable formulations which can be used to improve bioavailability.10-22-2009

Heike Ebendorff-Heidepriem, Adelaide AU

Patent application numberDescriptionPublished
20110045298FABRICATION OF NANOWIRES - A method of forming a nanowire is disclosed. In one embodiment, a primary preform is formed comprising at least one central region and a support structure. The primary preform is then drawn to a cane, which is then inserted into an outer portion, to form a secondary preform. The secondary preform is then drawn until the at least one central portion is a nanowire. The method can produce nanowires of far greater length than existing methods, and can reduce the likelihood of damaging the nanowire when handling.02-24-2011

Heike Ebendorff-Heidepriem, South Australia AU

Patent application numberDescriptionPublished
20090028488FABRICATION OF NANOWIRES - A method of forming a nanowire is disclosed. In one embodiment, a primary preform is formed comprising at least one central region and a support structure. The primary preform is then drawn to a cane, which is then inserted into an outer portion, to form a secondary preform. The secondary preform is then drawn until the at least one central portion is a nanowire. The method can produce nanowires of far greater length than existing methods, and can reduce the likelihood of damaging the nanowire when handling.01-29-2009
20090220785METHOD AND DEVICE FOR FORMING MICROSTRUCTURED FIBRE - A die and method for extruding an extrudable material to form an extruded member is described. In one embodiment, the die comprises a barrier member comprising a plurality of feed channels that extend through the barrier member. Furthermore, the die incorporates a passage forming member extending from the barrier member substantially in the direction of extrusion. The feed channels are arranged with respect to the passage forming member to allow the extrudable material to substantially flow about the passage forming member to form a corresponding passage in the extruded member.09-03-2009
20100237255OPTICAL FIBER SENSOR - A sensor based on optical fiber technology is described. The sensor includes an elongate core for propagating light having an excitation wavelength; an interaction region that includes a fluorescent material for excitation by the propagated light to produce fluorescent light; and an interface region defining a boundary between the elongate core and the interaction region. The elongate core of the sensor is adapted to increase an intensity of the propagated light at the interface region to increase the amount of captured fluorescent light in the elongate core.09-23-2010

Heike Euting, Bocholt DE

Patent application numberDescriptionPublished
20110092691Method For Filtering Nucleic Acids, In Particular From Fixed Tissue - The invention relates to a method for filtering nucleic acids, to a kit for carrying out the method according to the invention and to a novel use of magnetic particles for filtering a biological sample. The method according to the invention comprises the following steps: a) the sample is held in an aqueous solution; b) lysing of the sample; c) separation of cellular debris; and d) the nucleic acids are isolated from the solution, steps (a) to (c) taking place under non-chaotropic conditions.04-21-2011

Heike Faulhammer, Saint Germain En Laye FR

Patent application numberDescriptionPublished
20100105812COPOLYAMIDE, COMPOSITION CONTAINING SUCH COPOLYAMIDE AND USE THEREOF - The invention relates to a copolyamide containing at least two patterns (monomers) and of the following general formula A/(Cz diamine)·(Cw diacid) in which: z is the number of carbon atoms of the diamine and w is the number of carbon atoms of the diacid; and A is selected from a pattern obtained from an amino acid and a pattern of the general formula (Cx diamine)·(Cy diacid)04-29-2010

Heike Fischer, Meerbusch DE

Patent application numberDescriptionPublished
20080208209Device for delivering a self-expanding stent in a vessel of the body - The present invention relates to a device for delivering a self-expanding stent in a vessel of the body. The device comprises a tubular sheath which, in a distal section, keeps the stent radially compressed, and a pusher element, which is guided in the tubular sheath, in order to stabilize the stent when the sheath is pulled back. A handle is also provided, with a passage via which the pusher element is secured on the handle. The device further comprises a tubular rod which is fixedly connected to the handle and inside which the pusher element is provided, and which is provided at least in part with regularly spaced elevations and with depressions lying between the elevations. In addition, a movable element is provided which is arranged movably over the rod, distally from the handle, and whose movement in the proximal direction allows the sheath to be pulled back.08-28-2008

Heike Flösser-Müller, Ludwigshafen DE

Patent application numberDescriptionPublished
20090280075METHOD FOR INCREASING THE SUN PROTECTION FACTOR OF A COSMETIC AND/OR DERMATOLOGICAL PREPARATION - The present invention relates to a method of increasing the sun protection factor of a cosmetic and/or dermatological preparation, to the use of UV-A filters for increasing the sun protection factor of such a preparation and to specific photoprotective cosmetic and/or dermatological preparations.11-12-2009

Heike Foelster, Hamburg DE

Patent application numberDescriptionPublished
20090208437GLYCOPYRROLATE IN COSMETIC PREPARATIONS - Glycopyrronium bromide, derivatives and/or isomers thereof in combination with one or more active substances selected from a list of substances as recited in the claims and/or in the form of a W/Si emulsion, an O/W gel, a soap gel stick, and/or a surfactant-containing cleansing formula, and corresponding cosmetic preparations, in particular deodorant/antiperspirant preparations.08-20-2009

Heike Gielen-Haertwig, Monheim DE

Patent application numberDescriptionPublished
20080255068Chemical Compound and Its Use - The present application relates to a novel tetrahydroquinoline derivative, to a process for its preparation, to its use on its own or in combination for treating and/or preventing diseases and to its use for preparing medicaments, in particular as an inhibitor of the cholesterol ester transfer protein (CETP) for the treatment and/or prevention of cardiovascular disorders, in particular hypolipoproteinaemias, dyslipidaemias, hypertriglyceridaemias, hyperlipidaemias, hypercholesterolaemias and arteriosclerosis.10-16-2008
200902146754-Chromenonyl-1,4-dihydropyridinecarbonitriles and the use thereof - The present application relates to novel 4-chromenonyl-1,4-dihydropyridinecarbonitriles, processes for their preparation, pharmaceutical compositions containing them, and their use for the treatment and/or prophylaxis of diseases, especially cardiovascular disorders.08-27-2009
20100003709Crystal Structure of Enzyme and Uses Thereof - This invention relates to crystallised human neutrophil elastase and the use of its three-dimensional structure to design modulators for human neutrophil elastase.01-07-2010
20100010024USE OF1,4-DIARYL-DIHYDROPYRIMIDINE-2-ON DERIVATIVES FOR TREATING PULMONARY ARTERIAL HYPERTENSION - The present application relates to the use of 1,4-diaryldihydropyrimidin-2-one derivatives of the formula (I) for the treatment and/or prophylaxis of pulmonary arterial hypertension and other types of pulmonary hypertension, and to the use thereof for the manufacture of medicaments for the treatment and/or prophylaxis of pulmonary arterial hypertension and other types of pulmonary hypertension.01-14-2010
201000224844-Chromenonyl-1,4-dihydropyridines and their use - The present application relates to novel 4-chromenonyl-1,4-dihydropyridines, process for their preparation, their use for the treatment and/or prophylaxis of diseases, and their use for the manufacture of medicaments for the treatment and/or prophylaxis of diseases, especially cardiovascular disorders.01-28-2010
20100022537I-PHENY 1-3,4-DIHYDROPYRIMIDIN-2(1H)-ONE DERIVATIVES AND THEIR USE - This invention relates to novel heterocyclic derivatives, processes for their preparation, and their use in medicaments, especially for the treatment of chronic obstructive pulmonary diseases, acute coronary syndrome, acute myocardial infarction and heart failure development.01-28-2010
20100184788HETEROCYCLIC DERIVATIVES - The invention relates to novel heterocyclic derivatives of the general formula (I), processes for their preparation, and their use in medicaments, especially for the treatment of chronic obstructive pulmonary diseases, acute coronary syndrome, acute myocardial infarction, and heart failure development.07-22-2010

Patent applications by Heike Gielen-Haertwig, Monheim DE

Heike Glowatz, Hilden DE

Patent application numberDescriptionPublished
20100209993PERMANENT INACTIVATION OF NUCLEASES - The present invention relates to the use of reagent for permanently inactivating nucleases wherein the reagent comprises an oxidizing agent, a protein denaturant and optionally a pH adjustor and to a method for permanently inactivating nucleases using said reagent.08-19-2010

Heike Gregorius, Koblenz DE

Patent application numberDescriptionPublished
20090030166Preparation of supported catalyst systems containing reduced amounts of aluminoxanes - The present invention relates to a process for preparing a catalyst solid for olefin polymerization, comprising a finely divided support, an aluminoxane and a metallocene compound, which comprises: a) firstly combining the finely divided support with the aluminoxane and subsequently b) adding the reaction product of a metallocene compound with at least one organometallic compound to the modified support, catalyst solids obtainable by this process, catalyst systems comprising these catalyst solids, their use for the polymerization of olefins and a process for the polymerization of olefins.01-29-2009
20090124770Supported Metal Alkyl Compound and Process for the Polymerization of Olefins in Its Presence - The present invention relates to pulverulent solids obtainable by reaction of a metal alkyl compound of a divalent or higher-valent metal and a finely divided support which on its surface bears functional groups which can form a chemical bond between the metal atom of the metal alkyl compound and the surface of the support, wherein the particles of the finely divided support have particle diameters of less than 1000 nm and less than 5% by weight of the metal alkyl compound is extractable in a single extraction of the pulverulent solid with 20 ml of heptane per gram of solid at 50° C. In addition, the invention relates to a process for preparing the pulverulent solids, a catalyst composition for the polymerization of olefins which comprises the pulverulent solids and polymerization processes using the catalyst composition.05-14-2009

Patent applications by Heike Gregorius, Koblenz DE

Heike Grewenig, Ledbury GB

Patent application numberDescriptionPublished
20100260919REDUCED FAT CHOCOLATE - The present invention provides a reduced fat chocolate composition comprising erythritol. In one embodiment the chocolate composition is characterised in that it has a total fat content of from 15 wt % to 24.9 wt %. In another embodiment the chocolate composition comprising erythritol is characterised in that it has a total fat content of from 15 wt % to 26 wt % and does not comprise inulin or fructo oligosaccharide (FOS). A process for the preparation of the chocolate composition is provided, said process having processing parameters similar to those for high fat chocolate.10-14-2010
20110014350CHOCOLATE COMPOSITION - The present invention provides a chocolate composition comprising erthyritol and one or more ingredients selected from maltodextrin, a high protein ingredient, maltitol and polydextrose. Erythritol may be used in place of some or all of the sucrose normally employed in a chocolate composition and thereby provide a chocolate composition having a reduced sugar and/or calorie content chocolate. A process for the preparation of the chocolate composition is also provided.01-20-2011

Heike Guder, Wiesloch DE

Patent application numberDescriptionPublished
20100287135CAPTURING OLAP ANALYSIS THREAD AS REFRESHABLE BUSINESS INTELLIGENCE DATA - Described herein are methods and systems for capturing OLAP analysis thread and transferring the data into a data visualization tool. According to one aspect, OLAP analysis step queries and the corresponding results are recorded and transferred to a data visualization tool. In another aspect, the data in the data visualization tool may be refreshed without affecting the data format.11-11-2010

Heike Heckroth, Wuppertal DE

Patent application numberDescriptionPublished
201000359006-Arylmethyl-substituted pyrazolopyrimidines - The invention relates to novel 6-arylmethyl-substituted pyrazolopyrimidines, process for their preparation and their use for producing medicaments for improving perception, concentration, learning and/or memory.02-11-2010
201100657306-CYCLYLMETHYL-AND 6-ALKYLMETHYL-SUBSTITUTED PYRAZOLEPYRIMIDINES - The invention relates to novel 6-cyclylmethyl- and 6-alkylmethyl-substituted pyrazolopyrimidines, process for their preparation and their use for producing medicaments for improving perception, concentration, learning and/or memory.03-17-2011

Patent applications by Heike Heckroth, Wuppertal DE

Heike Hugenberg, Langenfeld DE

Patent application numberDescriptionPublished
20100285965METHODS OF IMPROVING PLANT GROWTH - The invention relates to the use of at least one compound selected from the class of the enaminocarbonyl compounds for enhancing plants' intrinsic defenses and/or for improving plant growth and/or for enhancing the resistance of plants to plant diseases which are caused by fungi, bacteria, viruses, MLOs (11-11-2010

Heike Huscher, Berlin DE

Patent application numberDescriptionPublished
20100200888Silicon-Based Sub-Mount for an Opto-Electronic Device - A package for an optoelectronic device (e.g., a light emitting device such as a LED) includes a sub-mount including a silicon substrate having a thickness in the range of 350 μm-700 μm. The optoelectronic device is mounted on a die attach pad on the front-side surface of the substrate. Feed-through metallization in one or more via structures electrically couples the die attach pad to a contact pad on the back-side surface of the substrate.08-12-2010

Heike Idink, Esslingen DE

Patent application numberDescriptionPublished
20090222104ASYMMETRIC FORMATION OF PROSTHETIC COMPONENTS FOR THE MANIPULATION AND SUPPRESSION OF NATURAL FREQUENCIES - A hip joint prosthesis for implantation in the femur of a patient, wherein the shaft can be coupled with a ball head which in turn can be inserted rotatably in the hemispherical recess of a socket insert. To avoid squeaking the shaft is formed asymmetrically in its outer and/or inner geometry and/or material composition.09-03-2009
20090259318ASYMMETRIC FORMATION OF SOCKETS AND/OR SOCKET INSERTS FOR THE MANIPULATION AND SUPRESSION OF NATURAL FREQUENCIES - A socket or socket insert for a hip joint prosthesis, the shaft of which can be coupled with a ball head which in turn can be inserted in a rotatable manner in the hemispherical recess of the socket insert wherein the shaft can be implanted in the femur and the socket insert can be implanted directly or via a hip socket in the pelvic bone. To avoid squeaking, the socket and/or the socket insert are asymmetrically in their inner or outer geometries.10-15-2009

Heike Ilias, Wedemark DE

Patent application numberDescriptionPublished
20080258413Level Control System for a Vehicle, and Method for Operating a Level Control System for a Vehicle - A level control system for a vehicle includes a pressure generator (10-23-2008
20080288138Method for Controlling the Quantity of Air in a Self-Contained Air Supply System for a Chassis - In order to simplify air flow control in a self-contained air supply system, an average control speed is calculated on the basis of a defined movement of the air springs (11-20-2008

Heike Klesper, Bergisch Gladbach DE

Patent application numberDescriptionPublished
20100308307METHOD FOR PRODUCTION OF AN ORGANIC LIGHT EMITTING DIODE OR OF AN ORGANIC SOLAR CELL AND ORGANIC LIGHT EMITTING DIODES OR SOLAR CELLS PRODUCED THEREWITH - The present invention relates to an electronic device. Examples for such an electronic device are an optical detector, a laser diode, a field-quenching device, an optical amplifier, an organic solar cell or an organic light emitting diode.12-09-2010

Heike Kluson-Hesslinger, Freiberg DE

Patent application numberDescriptionPublished
20100032356Fuel Filter of an Internal Combustion Engine - A fuel filter of an internal combustion engine has a filter housing with a housing base body of cast metal and at least one lid. Screws are provided for attaching the at least one lid to the housing base body. A lid seal seals the at least one lid relative to the housing base body. The housing base body has screw receptacles for the screws and a seal seat for the lid seal. The screws are self-tapping screws. The screw receptacles and the seal seat are formed by casting technology without after machining.02-11-2010
20100032360Fuel Filter of a Motor Vehicle - A fuel filter of a motor vehicle is designed to be mounted in a traveling direction of the motor vehicle and has a filter housing with a housing base body. The housing base body has a front side facing in the traveling direction. The front side of the housing base body has an external, integrally formed rib structure configured and adapted as impact protection.02-11-2010
20110017657Filter Device, Especially Liquid Filter - A filter device comprises a hollow cylindrical filter element in a filter housing. The fluid that is to be purified is to radially flow through the filter element. The interior of the filter element forms an axial flow chamber for the fluid. An end plate is arranged on the front side of the filter element. An annular neck, onto which a sealing element is injection-molded, is connected to the end plate.01-27-2011

Heike Kniel, Heppenheim DE

Patent application numberDescriptionPublished
20090023749POLYMORPHIC FORMS OF 1-'4-(5-CYANOINDOL-3-YL)BUTYL-4-(2- -CARBAMOYLBENZOFURAN-5-YL) PIPERAZINE HYDROCHLORIDE - The invention relates to new crystalline modifications of the hydrochloride of 1-[4-(5-cyanoindol-3-yl)butyl]-4-(2-carbamoyl-benzofuran-5-yl)-piperazine, crystalline modification of the dihydrochloride of 1-[4-(5-cyanoindol-3-yl)butyl]-4-(2-carbamoyl-benzofuran-5-yl)-piperazine and amorphous 1-[4-(5-cyanoindol-3-yl)butyl]-4-(2-carbamoyl-benzofuran-5-yl)-piperazine hydrochloride which are suitable in particular for the preparation of solid medicaments for the treatment or prevention of depressive disorders, anxiety disorders, bipolar disorders, mania, dementia, substance-related disorders, sexual dysfunctions, eating disorders, obesity, fibromyalgia, sleeping disorders, psychiatric disorders, cerebral infarct, tension, for the therapy of side-effects in the treatment of hypogonadism, secondary amenorrhea, premenstrual syndrome and undesired puerperal lactation.01-22-2009
20100016332POLYMORPHIC FORMS OF 1-'4-(5-CYANOINDOL-3-YL) BUTYL-4-(2-CARBAMOYLBENZOFURAN-5-YL)PIPERAZINE HYDROCHLORIDE - The invention relates to new crystalline modifications of the hydrochloride of 1-[4-(5-cyanoindol-3-yl) butyl]-4-(2-carbomyl-benzofuran-5-yl)-piperazine, crystaline modification of the dihydrochloride of 1-[4-(5-cyanoindol-3-yl) butyl]-4-(2-carbomyl-benzofuran-5-yl)-piperazine and amorphous 1-[4-(5-cyanoindol-3-yl)butyl]-4-(2-carbamoyl-benzofuran-5-yl)-piperazine hydrochloride which are suitable in particular for the preparation of solid medicaments for the treatment or prevention of depressive disorders, anxiety disorders, bipolar disorders, mania, dementia, substance-related disorders, sexual dysfunctions, eating disorders, obesity, fibromyalgia, sleeping disorders, psychiatric disorders, cerebral infarct, tension, for the therapy of side-effects in the treatment of hypogonadism, secondary amenorrhea, premenstrual syndrome and undesired puerperal lactation.01-21-2010

Heike Launhardt, Freiburg DE

Patent application numberDescriptionPublished
20080201804Protein Production - The present invention relates to a method for producing heterologous glycosylated proteins in non-animal eukaryotic cells such as in transformed bryophyte, yeast, ciliate or algae cells. In particular, the method relates to a method for producing glycosylated proteins comprising animal glycosylation patterns—comprising sialic acid residues—, such as pharmaceutical proteins for use in mammals, e.g. humans, in bryophyte cells such as those of 08-21-2008
20100050292Galactosyltransferase - The invention discloses DNA molecules encoding galactosyltransferases, recombinant host cells, tissues or organisms comprising dysfunctional galactosyltransferase gene(s), recombinant host cells, tissues or organisms comprising an introduced functional galactosyltransferase gene, methods for the production of proteins therewith, methods for the production of galactosyltransferase and vectors and uses thereof.02-25-2010

Heike Mertsching, Sindelfingen DE

Patent application numberDescriptionPublished
20100015704PROCESS FOR THE ENRICHMENT OF MELANOCYTES BY MEANS OF MODIFIED SURFACES - The present invention relates to processes for obtaining melanocytes from a cell suspension, in particular from an epidermal cell suspension, by means of a culture vessel, wherein at least a part of the surface of the culture vessel facing the culture space, is modified, in particular functionalized, in particular by means of a low-pressure plasma process. Furthermore, the present invention relates to culture vessels which are modified, in particular functionalized, in particular by means of a low-pressure plasma process and are suitable for obtaining melanocytes and the use of such culture vessels for obtaining melanocytes.01-21-2010
20100120145THREE-DIMENSIONAL BIOCOMPATIBLE SKELETON STRUCTURE CONTAINING NANOPARTICLES - The invention relates to a cell culture system comprising a three-dimensional, biocompatible frame structure and biocompatible nanoparticles, a method for the cultivation of cells, and the preparation of cells or cell products and tissues per se by means of such a cell culture system.05-13-2010
20100216239ISOLATED NATURE-IDENTICAL COLLAGEN - The present invention concerns isolated collagen, the method for its production, and isolation of the collagen from collagen-containing tissues, as well as the use of the isolated collagen in a biomatrix as an in vitro test system, tissue replacement or organ replacement.08-26-2010
20100315628ARRANGEMENT AND METHOD FOR ANALYSIS OF BIOLOGICAL SAMPLES - The invention lies in the technical field of cell biology and transplantation medicine. It concerns devices and methods for rapid and noninvasive analysis or checking of biological samples, especially for sterility control, for characterization of infectious particles and microorganisms contained in the biological sample and for characterization of tissue cells and transplants. The main areas of application of the invention are biotechnological production of pharmacological active ingredients and therapeutic agents as well as transplantation medicine.12-16-2010

Heike Miertsch, Hamburg DE

Patent application numberDescriptionPublished
20090208437GLYCOPYRROLATE IN COSMETIC PREPARATIONS - Glycopyrronium bromide, derivatives and/or isomers thereof in combination with one or more active substances selected from a list of substances as recited in the claims and/or in the form of a W/Si emulsion, an O/W gel, a soap gel stick, and/or a surfactant-containing cleansing formula, and corresponding cosmetic preparations, in particular deodorant/antiperspirant preparations.08-20-2009

Heike Petrul, Berlin DE

Patent application numberDescriptionPublished
20090081207High affinity human and humanized anti-alpha5beta1 integrin function blocking antibodies with reduced immunogenicity - The present invention relates to recombinant human or humanized polypeptides which bind to α5β1 integrin with high affinity and blocking function. Further, diagnostic and pharmaceutic applications of the potypeptides are disclosed.03-26-2009
20090137002ANTI EPHB4 ANTIBODIES AND ANTIBODY FRAGMENTS - The invention concerns antibodies and antibody fragments, specifically recognising the EphB4 receptor comprising heavy chains and light chain, comprising light and heavy CDR's, and their use as medicament for the treatment of pathological angiogenesis, in particular cancer therapy.05-28-2009

Heike Pfistner, Ludwigshafen DE

Patent application numberDescriptionPublished
20090186231PROCESS FOR COATING PLASTIC OR METAL SURFACES - A method of coating surfaces of plastic or metal, which comprises treating the plastic or metal surface in question with an aqueous dispersion comprising 07-23-2009
20100178310AQUEOUS FORMULATION AND PROCESS FOR THE IMPREGNATION OF NON-LIVING-MATERIALS IMPARTING A PROTECTIVE ACTIVITY AGAINST PESTS - A formulation for the impregnation of non-living-materials, preferably textile materials, comprising at least a pesticide and a polymeric binder comprising as monomers at least ethylene and an unsaturated carboxylic acid, process for impregnating such materials and the use of such impregnated materials as mosquito-nets and for the protection of plants and other goods.07-15-2010
20100266792COMPOSITE MATERIALS AND METHOD FOR PRODUCTION THEREOF - Composite materials comprising at least one natural fiber, at least one thermoplastic polymer, and at least one random copolymer having a molar mass M10-21-2010
20100291231Compositions as Wound Sealant - The present invention relates to compositions which, in sprayable or form, are suitable as wound sealants for woody plants. The invention also relates to a method of protecting woody plants from infection with phytopathogenic fungi, in particular ESCA infection, using such wound sealants.11-18-2010
20110089075METHOD FOR COATING GLASS, POLYETHYLENE OR POLYESTER CONTAINERS, AND SUITABLE AQUEOUS FORMULATIONS FOR SAID COATING METHOD - A method of coating containers made of glass, polyethylene or polyester by treatment with a substantially paraffin-free aqueous formulation comprising 04-21-2011
20110130318ENZYME COMPOSITION COMPRISING ENZYME CONTAINING POLYMER PARTICLES - The present invention relates to an enzyme composition comprising enzyme containing polymer particles, which is useful for detergent compositions, in particular for liquid detergent compositions. In these enzyme containing particles, the particles comprise i) at least one enzyme, and ii) at least one polymer P, which is selected from homo- and copolymers having a backbone, wherein the C—C-backbone carries carboxylgroups, which may be present in the acidic form or in the neutralized form, and wherein the C—C-backbone comprises hydrophobic repeating units.06-02-2011

Patent applications by Heike Pfistner, Ludwigshafen DE

Heike Prenz, Dresden DE

Patent application numberDescriptionPublished
20090142916APPARATUS AND METHOD OF MANUFACTURING AN INTEGRATED CIRCUIT - On aspect is a method to manufacture an integrated circuit including a reshaping process of the wafer edge region and an apparatus to perform the reshaping process.06-04-2009

Heike Radeke, Dedham, MA US

Patent application numberDescriptionPublished
20090258901LIGANDS FOR MONOAMINE RECEPTORS AND TRANSPORTERS, AND METHODS OF USE THEREOF - One aspect of the present invention relates to heterocyclic compounds. A second aspect of the present invention relates to the use of the heterocyclic compounds as ligands for various mammalian cellular receptors, including dopamine, serotonin, or norepinephrine transporters. The compounds of the present invention will find use in the treatment of numerous ailments, conditions and diseases which afflict mammals, including but not limited to addiction, anxiety, depression, sexual dysfunction, hypertension, migraine, Alzheimer's disease, obesity, emesis, psychosis, schizophrenia, Parkinson's disease, inflammatory pain, neuropathic pain, Lesche-Nyhane disease, Wilson's disease, and Tourette's syndrome. An additional aspect of the present invention relates to the synthesis of combinatorial libraries of the heterocyclic compounds, and the screening of those libraries for biological activity, e.g., in assays based on dopamine transporters.10-15-2009

Heike SchÄcke, Berlin DE

Patent application numberDescriptionPublished
20080200519TETRAHYDRONAPHTHALENYLAMIDES, A PROCESS FOR THEIR PRODUCTION AND THEIR USE AS ANTI-INFLAMMATORY AGENTS - The present invention relates to the compounds of formula I,08-21-2008
200901375645-[(3,3,3-Trifluoro-2-hydroxy-1-arylpropyl)amino]-1H-quinolin-2-ones, A Process for Their Production and Their Use as Anti-inflammatory Agents - The present invention relates to compounds of formula I,05-28-2009
201000163385-[(3,3,3-Trifluoro-2-hydroxy-1-arylpropyl)amino]-1-arylquinolin-2-ones, a Process for their Production and their Use as Anti-inflammatory Agents - The present invention relates to compounds of formula I,01-21-2010
20100298311TETRAHYDRONAPHTHALENE DERIVATES, PROCESS FOR PREPARING THEM AND THEIR USE AS ANTIINFLAMMATORY AGENTS - The invention relates to multiply substituted tetrahydronaphthalene derivatives of the formula (Ia)11-25-2010

Patent applications by Heike SchÄcke, Berlin DE

Heike Schaecke, Berlin DE

Patent application numberDescriptionPublished
20080227820CYCLIC PHENYL-SUBSTITUTED INDAZOLS, A PROCESS FOR THEIR PRODUCTION AND THEIR USE AS ANTI-INFLAMMATORY AGENTS - The present invention relates to the compounds of formula I,09-18-2008
20100144742MULTIPLY-SUBSTITUTED TETRAHYDRONAPHTHALENE DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND THEIR USE AS ANTI-INFLAMMATORY AGENTS - The invention relates to multiply-substituted tetrahydronaphthalene derivatives of formula (I)06-10-2010

Patent applications by Heike Schaecke, Berlin DE

Heike Schauerte, Munchen DE

Patent application numberDescriptionPublished
20080275063Inhibitors of protein kinases - The present invention provides new compounds. The compounds are useful as CDK5 inhibitors, and accordingly they can be included in pharmaceutical compositions for treating any type of pain, inflammatory disorders, immunological diseases, proliferative diseases, infectious diseases, cardiovascular diseases and neurodegenerative diseases.11-06-2008
20090221581Methods of treating pain - The invention relates to methods of treating any type of pain comprising the administration of an effective amount of at least one inhibitor of cyclin-dependent kinases.09-03-2009
20100168144INHIBITORS OF PROTEIN KINASES - The present invention relates to inhibitors of cyclin-dependent kinases and therapeutic applications thereof. Furthermore, the invention relates to methods of preventing and/or treating any type of pain, inflammatory disorders, immunological diseases, proliferative diseases, infectious diseases, cardiovascular diseases and neurodegenerative diseases comprising the administration of an effective amount of at least one inhibitor of cyclin-dependent kinases. formula (I).07-01-2010
20100184780INHIBITORS OF PROTEIN KINASES - The present invention provides new compounds. The compounds are useful as CDK5 inhibitors, and accordingly they can be included in pharmaceuticals compositions for treating any type of pain, inflammatory disorders, immunological diseases, proliferative diseases, infectious diseases, cardiovascular diseases and neurodegenerative diseases. formula (I).07-22-2010
20100184789INHIBITORS OF PROTEIN KINASES - The present invention relates to inhibitors of cyclin-dependent kinases and therapeutic applications thereof. Furthermore, the invention relates to methods of preventing and/or treating any type of pain, inflammatory disorders, immunological diseases, proliferative diseases, infectious diseases, cardiovascular diseases and neurodegenerative diseases comprising the administration of an effective amount of at least one inhibitor of cyclin-dependent kinases.07-22-2010

Patent applications by Heike Schauerte, Munchen DE

Heike Schirmer-Ditze, Dusseldorf DE

Patent application numberDescriptionPublished
20080261852Bleach Reinforcer Combination for Use in Washing and Cleaning Agents - The performance of peroxide compounds, in particular when associated with bleaches for washing ink stains out of textiles, can be improved by a composition comprising: (i) a peroxygen-containing bleaching agent, (ii) a bleach activator selected from the group consisting of amide bleach activators, sulfonyl phenyl ester bleach activators, quaternary nitrogen substituted acetonitrile bleach activators, and mixtures thereof, and (iii) a compound selected from the group consisting of ligands corresponding to the general formula (I), bleach catalysts corresponding to the general formula (II), and mixtures thereof:10-23-2008
20100180388Ironing Pad Comprising a Solid Stain Treatment Composition - The invention relates to an ironing pad comprising a cover and a solid stain treatment composition. The solid stain treatment composition is produced from a solid material reversibly solidifying a fluid and a fluid stain treatment agent. The invention relates to a method for treating a stain on a textile fabric having such an ironing pad, the ironing pad being placed on the stain, and heat and/or pressure being applied to the ironing pad.07-22-2010
20100186268Ironing Pad Comprising Liquid Stain Treatment Agent - The invention relates to an ironing pad comprising a solid material (07-29-2010

Patent applications by Heike Schirmer-Ditze, Dusseldorf DE

Heike Schirmer-Ditze, Duesseldorf DE

Patent application numberDescriptionPublished
20090183317Detergent or Treatment Agent Portion - A dimensionally stable, single-piece detergent or treatment agent portion having a weight of at least 50 g, having a system for controlling the solubility of the detergent or treatment agent. In washing, treating, or rinsing cycles of a washing machine for textiles, a maximum 50 wt % of the detergent or treatment agent portion dissolves or disperses in municipal water (16° d) at a maximum temperature of 20° C. as dissolves or disperses in municipal water (16° d) at a temperature of 50° C., enabling targeted release of the active substances in the portion during the cycles of a washing or treating program using heated water.07-23-2009
20090192069Washing or Cleaning Composition with Size-Optimized Active Bleaching Ingredient Particles - A bleaching agent, as well as a bleach-intensifying transition metal complex compound, incorporated in shelf-stable fashion into agents made up of multiple powder components. A solid washing detergent or cleaning agent containing particulate alkali percarbonate having an average particle size in the range from 1.0 to 2.0 mm, and particles that contain a bleach-intensifying transition metal complex compound, having an average particle size in the range from 0.8 mm to 1.6 mm.07-30-2009

Heike Schluckwerder, Salmendingen DE

Patent application numberDescriptionPublished
20110100684METHOD FOR MANUFACTURING AN ELECTRICAL CONDUCTOR BY APPLYING AT LEAST ONE PASTE, IN PARTICULAR A THICK-FILM PASTE - A method for manufacturing an electrical conductor by applying at least one paste, in particular a thick-film paste, to a substrate by a dispensing operation, wherein the paste is applied in at least one strand.05-05-2011

Heike Schluckwerder, Stuttgart DE

Patent application numberDescriptionPublished
20090169900Ceramic Resistor Element or Sensor Element - A ceramic resistor element or sensor element includes a ceramic substrate, which is exposable to a gas atmosphere containing carbon compounds, the ceramic substrate being provided with a coating. The coating includes copper, cerium and/or vanadium.07-02-2009

Heike Schmidt, Obersulm DE

Patent application numberDescriptionPublished
20100059240METHOD FOR TIGHTENING A SCREW CONNECTION AND SCREW DRIVING TOOL - Disclosed is a method for screwing in and tightening a screw connection (03-11-2010

Heike SchÖne, Elsvra DE

Patent application numberDescriptionPublished
20100126891PACKAGING DEVICE AND PACKAGING SYSTEM FOR ESSENTIALLY FLAT OBJECTS, FOR EXAMPLE LITHIUM-ION CELLS - Packaging device (05-27-2010

Heike Schuchmann, Stutensee DE

Patent application numberDescriptionPublished
20080220071Aqueous Suspensions of Poorly Water-Soluble and Water-Insoluble Active Ingredients and Drying Powder Produced Therefrom - Aqueous suspensions comprising: (a) at least one sparingly water-soluble or water-insoluble active agent in the form of nanoparticulate particles; (b) at least one whey component selected from the group consisting of whey proteins, whey protein hydrolysates, and mixtures thereof; and (c) at least one sucrose fatty acid ester having an HLB value of 10 to 18; processes for preparing such aqueous suspensions; powders and oil-miscible compositions prepared therefrom and uses therefore.09-11-2008
20100324211METHOD FOR THE HIGH-PRESSURE DISPERSION OF REACTIVE MONOMERS - The object of the invention is a method for the dispersion of reactive monomers, wherein a monomer emulsion (12-23-2010

Heike Sederoff, Raleigh, NC US

Patent application numberDescriptionPublished
20080280358Synthetic Peptides that Cause F-Actin Bundling and Block Actin Depolymerization - Synthetic peptides derived from sucrose synthase, and having homology to actin and actin-related proteins, sharing a common motif, useful for causing acting bundling and preventing actin depolymerization. Peptides exhibiting the common motif are described, as well as specific synthetic peptides which caused bundled actin and inhibit actin depolymerization. These peptides can be useful for treating a subject suffering from a disease characterized by cells having neoplastic growth, for anti-cancer therapeutics, delivered to subjects solely, or concomitantly or sequentially with other known cancer therapeutics. These peptides can also be used for stabilizing microfilaments in living cells and inhibiting growth of cells.11-13-2008

Heike Smula, Heidenheim DE

Patent application numberDescriptionPublished
20100192800BOGIE FOR A RAIL VEHICLE WHICH HAS A DRIVE - The invention relates to a bogie for a locomotive08-05-2010

Heike Suthaus, Walzbachtal-Joehlingen DE

Patent application numberDescriptionPublished
20080201182Method for determining an aggregated forecast deviation - In the method for determining an aggregated forecast deviation, deviations are aggregated in a predefined environment at all reference points in time and are incorporated into an error determination. Using this method, the aggregated forecast deviation for a product is determinable so that this product may be made available in a sufficient quantity. The method is thus suitable, e.g., for disposition planning, warehouse management, or warehousing products of all types.08-21-2008

Heike Wagner, Heidelberg DE

Patent application numberDescriptionPublished
20090306024Combination preparations of o-acetylsalicylic acid salts - The present invention relates to a fixed combination comprising a salt of o-acetylsalicylic acid with a basic amino acid as component A and an HMG-CoA reductase inhibitor as component B, a medicament comprising this combination and a process for its production.12-10-2009

Heike Wessendorf, San Francisco, CA US

Patent application numberDescriptionPublished
20090023131CIRCUIT ARRANGEMENT FOR INJECTING NUCLEIC ACIDS AND OTHER BIOLOGICALLY ACTIVE MOLECULES INTO THE NUCLEUS OF HIGHER EUCARYONTIC CELLS USING ELECTRICAL CURRENT - The invention relates to a novel circuit arrangement for electrotransfection or electrofusion, which enables the transportation of DNA and/or other biologically active molecules to the nucleus of higher eukaryotic cells or the fusion of cells, independent of cell division and with reduced cell mortality.01-22-2009
20110117654BUFFER SOLUTION FOR ELECTROPORATION AND A METHOD COMPRISING THE USE OF THE SAME - A method for introducing biologically active molecules into animal or human cells using an electric current includes suspending the cells and dissolving the biologically active molecules in a buffer solution including HEPES and at least 10 mmol×105-19-2011

Patent applications by Heike Wessendorf, San Francisco, CA US

Heike Williams, Schwabenheim DE

Patent application numberDescriptionPublished
20100179205Composition for Enhanced Antiparasitic Activity - The invention relates to antiparasitic compositions comprising a combination of atipamezole or its pharmaceutically acceptable salt and amitraz and their use in a method to control ectoparasite infestations on animals.07-15-2010
20110059988ISOXAZOLINE COMPOSITIONS AND THEIR USE AS ANTIPARASITICS - This invention relates to methods for controlling parasitic infestations of animals and their environments, and, more particularly, to methods using isoxazolines to control parasites in or on animals or in their environments, as well as treat parasitoses of animals. The isoxazolines include 4-(isoxazolinyl)-benzamides (specifically, substituted 4-(5-(halomethyl)-5-phenylisoxazolin-3-yl)-benzamides) and 4-(isoxazolinyl)-benzothioamides (specifically, substituted 4-(5-(halomethyl)-5-phenyl-isoxazolin-3-yl)-benzothioamides). This invention also relates to compositions comprising the isoxazolines for use in such methods, the use of the isoxazolines to make medicaments for use in such methods, and kits comprising the isoxazolines for carrying out such methods. This invention further relates to the use of the isoxazolines as medicaments, particularly medicaments that can be used in the above-referenced method.03-10-2011

Heike Ziebarth, Berlin DE

Patent application numberDescriptionPublished
20080220418Method For Providing Dna Fragments Derived From An Archived Sample - Aspects of the present invention relate to compositions and methods for providing DNA fragments from an archived sample (e.g., paraffin-embedded and/or fixed-tissue biopsies, etc). Particular aspects provide methods whereby high yields of DNA are isolated as well as a substantial portion of the DNA consists of long DNA fragments, and where the isolated genomic DNA is free of associated or cross-linked contaminants like proteins, peptides, amino acids or RNA. The methods are facile, cost-effective, an are characterized by high reproducibility and reliability. Particular aspects provide methods for providing DNA fragments derived from an archived sample, wherein the yield of DNA before, for example, an amplification step is at least 20%, and amplicons up to a length of about 1,000 base pairs are amplifiable. 09-11-2008