Patent application number | Description | Published |
20100068140 | MYELIN DETECTION USING BENZOFURAN DERIVATIVES - The present invention relates to methods for the detection of myelin and a quantitative measurement of its local concentration in a sample using a benzofuran compound or its radioisotope derivatives. In one embodiment a method of myelin detection comprises identifying a subject at risk of or diagnosed with a myelin-associated neuropathy, parenterally administering to the subject the benzofuran compound, or a derivative of the compound, and determining myelination in the subject by detecting binding in the sample. In one embodiment, the invention provides a method of imaging myelinated tissue in a surgical field of mammalian tissue comprising the steps of contacting the surgical site with the benzofuran compound or a radioisotope derivative of the compound, and detecting binding in the surgical site. In yet another embodiment, a method of imaging spinal cord and spinal nerve root tissue is provided comprising the steps of parenteral administration of a radioisotope derivative of the benzofuran compound and detecting the radioisotope derivative within the spinal canal and intervertebral foramen. Methods of quantification of binding of the benzofuran compound or its derivatives are also provided. | 03-18-2010 |
20110305635 | MYELIN DETECTION USING BENZOFURAN DERIVATIVES - The present invention relates to methods for the detection of myelin and a quantitative measurement of its local concentration in a sample using a benzofuran compound or its radioisotope derivatives. In one embodiment a method of myelin detection comprises identifying a subject at risk of or diagnosed with a myelin-associated neuropathy, parenterally administering to the subject the benzofuran compound, or a derivative of the compound, and determining myelination in the subject by detecting binding in the sample. In one embodiment, the invention provides a method of imaging myelinated tissue in a surgical field of mammalian tissue comprising the steps of contacting the surgical site with the benzofuran compound or a radioisotope derivative of the compound, and detecting binding in the surgical site. In yet another embodiment, a method of imaging spinal cord and spinal nerve root tissue is provided comprising the steps of parenteral administration of a radioisotope derivative of the benzofuran compound and detecting the radioisotope derivative within the spinal canal and intervertebral foramen. Methods of quantification of binding of the benzofuran compound or its derivatives are also provided. | 12-15-2011 |
Patent application number | Description | Published |
20140013319 | PROVIDING GUIDANCE FOR SOFTWARE INSTALLATION - A computer receives information from a user, which includes the identity of and installation preferences for the software to be installed on a second computer. Information about the environment of the second computer is gathered by the computer. The computer defines a set of search parameters based on the information received and the environment of the second computer. The computer searches for data stored on storage devices and the Internet. The computer retrieves the data, associated to a second installation of the software on a third computer, which relates to the installation of software on the second computer. The computer generates guidance for installation of the software on the second computer, based on the identity of the software to be installed, installation preferences for the software to be installed, the environment of the second computer, and the data associated to an installation of the software on a third computer. | 01-09-2014 |
20140026130 | PROVIDING GUIDANCE FOR SOFTWARE INSTALLATION - A computer receives information from a user, which includes the identity of and installation preferences for the software to be installed on a second computer. Information about the environment of the second computer is gathered by the computer. The computer defines a set of search parameters based on the information received and the environment of the second computer. The computer searches for data stored on storage devices and the Internet. The computer retrieves the data, associated to a second installation of the software on a third computer, which relates to the installation of software on the second computer. The computer generates guidance for installation of the software on the second computer, based on the identity of the software to be installed, installation preferences for the software to be installed, the environment of the second computer, and the data associated to an installation of the software on a third computer. | 01-23-2014 |