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Hegedus

Béla Hegedüs, Budapest HU

Patent application numberDescriptionPublished
20100081668POLYMORPHS OF 5--6-CHLORO-1,3-DIHYDRO-2H-INDOL-2-ONE HYDROBROMIDE AND PROCESSES FOR PREPARATION THEREOF - The present invention provides pharmaceutically applicable compounds and polymorphs belonging to the ziprasidone hydrobromide compound group with antipsychotic effect. The present invention provides hydrobromide polymorphs of 5-{-2-[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]-ethyl}-6-chloro-1,3-dihydro-2H-indol-2-one, ziprasidone of Formula (I) having neuroleptic activity.04-01-2010

Csaba Hegedus, Mako HU

Patent application numberDescriptionPublished
20100287555USING COMPOSITE SYSTEMS TO IMPROVE FUNCTIONALITY - Systems and methods are provided for enabling communication between a composite system providing additional functionality not contained in existing legacy systems and other existing systems using different commands, variables, protocols, methods, or instructions, when data may be located on more than one system. In an embodiment, multiple software layers are used to independently manage different aspects of an application. A business logic layer may be used in an embodiment to facilitate reading/writing operations on data that may be stored locally and/or on external systems using different commands, variables, protocols, methods, or instructions. A backend abstraction layer may be used in an embodiment in conjunction with the business logic layer to facilitate communication with the external systems. A user interface layer may be used in an embodiment to manage a user interface, a portal layer to manage a user context, and a process logic layer to manage a workflow.11-11-2010

Csaba Hegedus, Debrecen HU

Patent application numberDescriptionPublished
20100144919Reactive polymeric nanoparticles (RPNPS) for restoration materials in dentistry - A method is disclosed in which modified and generic dental resins are combined as mixtures with reactive polymeric nanoparticles (RPNPs). Nanoparticles as additives clearly demonstrate that the RPNPs significantly influence the mechanical and shrinkage properties of the matrix and composites.06-10-2010

Erzsébet Hegedüs, Budapest HU

Patent application numberDescriptionPublished
20100267711METHOD OF ENHANCING CELLULAR PRODUCTION OF MOLECULAR CHAPERONE, HYDROXYLAMINE DERIVATIVES USEFUL FOR ENHANCING THE CHAPERONE PRODUCTION AND THE PREPARATION THEREOF - A method of increasing expression of a molecular chaperon by a cell and/or enhancing the activity of a molecular chaperon in cells is provided. The method comprises treating a cell that is exposed to a physiological stress which induces expression of a molecular chaperon by the cell with an effective amount of a certain hydroxylamine derivative to increase the stress. Alternatively, an hydroxylamine derivative can be administrated to a cell before it is exposed to a physiological stress which induces expression of a molecular chaperon by the cell. Preferably, the cell to which an hydroxylamine derivative is administered is an eukaryotic cell. The hydroxylamine derivative corresponds to the formulae (I) or (II).10-21-2010

Gergo Hegedus, Szeged HU

Patent application numberDescriptionPublished
20120100623METHOD OF OLIGONUCLEOTIDE SEQUENCING BY MASS SPECTROMETRY - A computer-implemented method for confirming the nucleotide sequence of an oligonucleotide is provided. In certain embodiments, the method comprises: a) inputting the nucleotide sequence of an oligonucleotide; b) executing an algorithm that provides the predicted molecular formulas of fragments of the oligonucleotide; c) comparing the predicted m/z values of the predicted molecular formulas to experimentally-obtained m/z values obtained by analysis of the oligonucleotide by tandem mass spectrometry to determine if the predicted masses correspond with the experimentally-obtained masses. The method may be used, for example, to confirm the identity of a. oligonucleotide after it is synthesized, i.e., to confirm that it has the expected sequence.04-26-2012

Gyula Julius Hegedus, Langley CA

Patent application numberDescriptionPublished
20080241787DENTAL WEDGES AND METHODS - Improved dental wedge having curved elongate body approximating the anatomical curvature of a tooth undergoing repair to hold the matrix in conformity with the anatomical curvature of said tooth. The wedges comprising a curved elongate body having proximal and distal ends and tapering from the proximal end to the distal end, the elongate body further having a bottom surface, an inside surface and an outside surface opposite the inside surface, the curvature of the elongate body being towards the inside surface, and the bottom surface adjacent the insertion portion being curved upwards relative to the remainder of the bottom surface. The elongate body may be generally triangular in cross-section, and the inside surface is concave and the outside surface is convex transversely to the elongate body.10-02-2008

Lajos Hegedus, Budapest HU

Patent application numberDescriptionPublished
20100076008Pharmaceutical compositions containing plasma protein - The invention is related to water-soluble products and pharmaceutical formulations in solid or liquid form mainly for parenteral use. They consist of or comprise a therapeutically active substance (having low aqueous solubility and a substantial binding affinity to plasma proteins) and a plasma protein fraction in controlled aggregation state, whereby the said active substance and the said protein fraction are bound to each other by way of non-covalent bonds. It also covers processes for the preparation of the product and pharmaceutical formulation by dissolving the water-insoluble active substance in a water-miscible, pharmaceutically acceptable solvent, combining said solution with the aqueous solution of a plasma protein fraction in controlled aggregation state whereby a true solution is obtained containing the said active substance and the said protein fraction bound together by way of non-covalent bonds. Optionally a further pharmaceutically acceptable auxiliary additive—such as a protein aggregation controller and/or a stabilizer—may be present. The organic solvent is eliminated by dialysing, ultrafiltrating, diafiltrating and/or lyophilising. The solid products consisting of the active substance and the protein are also protected. On optional dissolution in water clear, liquid compositions are obtained suitable for direct parenteral or other administration. Method of treatment is also covered. A series of water-insoluble substances is enlisted with appropriate protein fractions to be used.03-25-2010

Patent applications by Lajos Hegedus, Budapest HU

Laszlo Hegedus, Budapest HU

Patent application numberDescriptionPublished
20110288329PROCESS FOR THE PREPARATION OF TRANS 4-AMINO-CYCLOHEXYL ACETIC ACID ETHYL ESTER HCL - The invention relates to a process for the preparation of trans 4-amino-cyclohexil ethyl acetate HCl wherein11-24-2011

Viktor Hegedüs, Wehingen DE

Patent application numberDescriptionPublished
20100272532System and Method for Marking any Non-Living or Living Objects, and Marking Element and Use of Same for Marking any Objects, in particular for Object Control and Object Management - The invention relates to a system and a method for marking any non-living or living objects, in particular medical instruments, implants, structural parts, e.g. tools, machines, items of clothing, jewelry, and many others, and to a marking element and the use of same for marking any objects, in particular for object control and object management. For this purpose, a marking system is proposed that comprises a holding device for the object (10-28-2010