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Heather Aeder, Flourtown, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20090094056 | Systems And Methods For Projecting Sample Store Activities That Are Restricted In Non-Sample Stores - Systems and methods are provided for estimating non-sampled store activities by applying projection factors to sampled store activities taking into account restrictions on non-sampled store activities. The systems and methods adjust data projection factors for managed healthcare plans that have restrictions in non-sampled stores to prevent unrestricted activity under these plans at sample stores from being projected into non-sample stores where such projected activity would be restricted. Conventional sampled-to-non-sampled store projection factors leading to restricted plan activities are reallocated to non-restricted plan activities in the non-sample store based on the historical ratio of such activities observed in sample stores. | 04-09-2009 |
Heather Allderidge, Derby GB
| Patent application number | Description | Published |
|---|---|---|
| 20090260355 | Stirling engine assembly - A Stirling engine assembly comprising a Stirling engine ( | 10-22-2009 |
| 20110025055 | Domestic combined heat and power generation system - A domestic combined heat and power generation system comprising a pair of Stirling engines mounted so that the vibrations of one substantially counteract the vibrations of the other. At least one engine burner heats the heads of the engines. An auxiliary burner provides additional heat. Gas and air are supplied to the engine burner and auxiliary burner controlled by a controller. A heat exchanger recovers heat from the exhaust gases from the engine burner and auxiliary burner and provide a heat output. An electrical output is provided from an alternator of each engine. The engines having a combined electrical power output of less than 2.5 kW. | 02-03-2011 |
Heather Beam-Brennan, Red Bank, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20100016967 | RESORBABLE MEDICAL IMPLANTS AND RELATED METHODS - Biocompatible, resorbable medical implants and related methods are disclosed in which the implant can be made of a collagen matrix for filling a space after partial or total resection of the trapezium bone of the wrist. The resorbable medical implant can include a plurality of surface projections, and the collagen matrix can be folded or spirally wound about itself to form a spiral roll. | 01-21-2010 |
Heather Beck Knowles, Chelmsford, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20110071395 | TRANSESOPHAGEAL AND TRANSNASAL, TRANSESOPHAGEAL ULTRASOUND IMAGING SYSTEMS - A semi-invasive ultrasound imaging system for imaging biological tissue includes a transesophageal probe or a transnasal, transesophageal probe connected to a two-dimensional ultrasound transducer array, a transmit beamformer, a receive beamformer, and an image generator. The two-dimensional transducer array is disposed on a distal portion of the probe's elongated body. The transmit beamformer is connected to the transducer array and is constructed to transmit several ultrasound beams over a selected pattern defined by azimuthal and elevation orientations. The receive beamformer is connected to the transducer array and is constructed to acquire ultrasound data from the echoes reflected over a selected tissue volume. The tissue volume is defined by the azimuthal and elevation orientations and a selected scan range. The receive beamformer is constructed to synthesize image data from the acquired ultrasound data. The image generator is constructed to receive the image data and generate images that are displayed on an image display. Preferably, the image generator is constructed to generate, from the image data, several orthographic projection views over the selected tissue volume. | 03-24-2011 |
Heather Behanna, Chicago, IL US
| Patent application number | Description | Published |
|---|---|---|
| 20100240668 | Myosin Light Chain Kinase Inhibitor Compounds, Compositions and Related Methods of Use - Pyridazinyl compounds, compositions and related methods of use. | 09-23-2010 |
Heather Cumming Rowell, Weymouth, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100146686 | Disposable Non-Woven, Flame-Resistant Coveralls - A non-woven, flame resistant fabric and a disposable coverall made from the fabric. The non-woven, flame resistant fabric is made of a plurality of NOMEX® synthetic fibers, a plurality of KEVLAR® synthetic fibers, and a plurality of electrostatic dissipative fibers. The coverall has an upper section for covering the shoulder, chest, back and abdominal regions of a wearer. The upper section has long sleeves to cover the arms of the wearer and a collar to cover the neck region of wearer. The coverall also has a waist section contiguous with the upper section for covering the waist region of a wearer, and a pair of leg sections for covering the legs of the wearer. Each leg section has an upper portion contiguous with the waist section. The coverall also has a seat section contiguous with the waist section and the upper portions of the leg sections. The coverall has a two-way zipper extending from the collar section to the waist section. | 06-17-2010 |
Heather Dans, Marshfield, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20120132658 | METHOD AND APPARATUS FOR CALIBRATING THERMOMETERS - A calibration device allows accurate and consistent creation of ice baths and aids in the calibration of food safety thermometers. Such devices include a calibration wrench on a cup lid for holding and calibrating a thermometer, a stem thermometer access hole on the cup lid, an insulated cup for holding a substance to be measured, and a liquid crystal reversible temperature label on the cup. | 05-31-2012 |
Heather Degruttola, Newton, NH US
| Patent application number | Description | Published |
|---|---|---|
| 20100004175 | NOVEL BMP-12-RELATED PROTEINS AND METHODS OF THEIR MANUFACTURE - The invention provides novel BMP-12-related proteins, including methods of their manufacture. The proteins include substituted, truncated and substituted-truncated BMP-12-related proteins. The substituted BMP-12-related proteins contain a substitution at one or more oxidation-sensitive methionine residues with non-methionine residues, such as norleucine. The substituted BMP-12-related proteins exhibit normal bioactivity and enhanced resistance to oxidation, relative to the unsubstituted protein. The truncated BMP-12-related proteins exhibit enhanced activity. | 01-07-2010 |
Heather Desaire, Lawrence, KS US
| Patent application number | Description | Published |
|---|---|---|
| 20090311289 | VACCINE - The present invention relates, in-general, to Human immunodeficiency virus (HIV), and in particular to a carbohydrate-based vaccine for HIV and to methods of making and using same. | 12-17-2009 |
| 20110105735 | METHODS OF PRODUCING AND PURIFYING PROTEINS - Methods of producing and purifying proteins that comprise a glycan tag are provided. In some embodiments, a protein may be modified to include a glycan tag so as to facilitate production of the protein, e.g., by promoting protein secretion and/or promoting protein solubility. In some embodiments, the present disclosure provides methods wherein a protein may be modified to include a glycan tag, which may then be used as an affinity tag for purification. | 05-05-2011 |
Heather Eacker, Seattle, WA US
| Patent application number | Description | Published |
|---|---|---|
| 20100293697 | ARTICLE OF CLOTHING - An article of clothing includes a front portion and a rear portion, the rear portion being substantially enclosed across the torso. A location below the waist includes an opening that more readily allows the wearer to eliminate bodily waste. | 11-25-2010 |
Heather Eames, Lansdale, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20100204733 | TRANSCONNECTOR - A transconnector for use in interconnecting a pair of longitudinal spinal rods in a spinal fixation procedure. The transconnector includes a bridge member and first and second spinal rod engaging members. The bridge member may include first and second members, wherein the first and second members are moveably associated with one another so that the distance between the first and second spinal rod engaging members can be adjusted. The first and second spinal rod engaging members include a rod receiving channel for receiving one of the spinal rods therein. The spinal rod engaging members may be articulating in, for example, the yaw and roll positions or non | 08-12-2010 |
Heather Fahlenkamp, Broken Arrow, OK US
| Patent application number | Description | Published |
|---|---|---|
| 20100178676 | METHODS FOR ANTIBODY PRODUCTION - The present invention relates to methods of constructing an integrated artificial immune system that comprises appropriate in vitro cellular and tissue constructs or their equivalents to mimic the normal tissues that interact with vaccines in mammals. The artificial immune system can be used to test the efficacy of vaccine candidates in vitro and thus, is useful to accelerate vaccine development and testing drug and chemical interactions with the immune system. | 07-15-2010 |
Heather Fahlenkamp, Cleveland, OK US
| Patent application number | Description | Published |
|---|---|---|
| 20090011455 | DISEASE MODEL INCORPORATION INTO AN ARTIFICIAL IMMUNE SYSTEM (AIS) - The present invention relates to methods of constructing an integrated artificial immune system that comprises appropriate in vitro cellular and tissue constructs or their equivalents to mimic the tissues of the immune system in mammals. The artificial immune system can be used to test the efficacy of vaccine candidates and other materials in vitro and thus, is useful to accelerate vaccine development and testing drug and chemical interactions with the immune system, coupled with disease models to provide a more complete representation of an immune response. | 01-08-2009 |
| 20100105135 | POROUS MEMBRANE DEVICE THAT PROMOTES THE DIFFERENTIATION OF MONOCYTES INTO DENDRITIC CELLS - Dendritic cells (DCs) for research and clinical applications are typically derived from purified blood monocytes that are cultured in a cocktail of cytokines for a week or more. Because it has been suggested that these cytokine-derived DCs may be deficient in some important immunological functions and might not accurately represent antigen-presenting cell (APC) populations found under physiologic conditions, there is a need for methods that allow the generation of DCs in a more physiologically relevant manner. The present invention comprises a simple and reliable technique for generating large numbers of highly purified DCs, based on a single migration of blood monocytes through endothelial cells that are cultured in, for example, a Transwell® device. The resultant APCs, harvested from the lower Transwell® chamber, resemble other in vitro-generated DC populations in their expression of major histocompatibility (MHC) and costimulatory molecules, ability to phagocytose foreign antigens, and capacity to trigger antigen-specific T cell responses. | 04-29-2010 |
| 20100159443 | DISEASE MODEL INCORPORATION INTO AN ARTIFICIAL IMMUNE SYSTEM (AIS) - The present invention relates to methods for preparing an artificial immune system. The artificial immune system comprises a cell culture comprising a three-dimensional matrix comprising lymphoid tissue, a three-dimensional matrix comprising epithelial and/or endothelial cells, and diseased cells. The artificial immune system of the present invention can be used for in vitro testing of vaccines, adjuvants, immunotherapy candidates, cosmetics, drugs, biologics and other chemicals. | 06-24-2010 |
| 20100184148 | IN VITRO GERMINAL CENTERS - The present invention incorporates germinal centers (GCs) into three-dimensional (3D) engineered tissue constructs (ETCs). In an embodiment, we have incorporated the GC in the design of an artificial immune system (AIS) to examine immune responses to vaccines and other compounds. Development of an in vitro GC adds functionality to an AIS, in that it enables generation of an in vitro human humoral response by human B lymphocytes that is accurate and reproducible, without using human subjects. The invention also permits evaluation of, for example, vaccines, allergens, and immunogens, and activation of human B cells specific for a given antigen, which can then be used to generate human antibodies. In an embodiment of the present invention the function of the in vitro GC is enhanced by placing FDCs and other immune cells in a 3D ETC; FDCs appear more effective over a longer time (antibody production is sustained for up to about 14 days. | 07-22-2010 |
| 20100279277 | METHODS OF EVALUATING A TEST AGENT IN A DISEASED CELL MODEL - The present invention relates to methods of constructing an integrated artificial immune system that comprises appropriate in vitro cellular and tissue constructs or their equivalents to mimic the tissues of the immune system in mammals. The artificial immune system can be used to test the efficacy of vaccine candidates and other materials in vitro and thus, is useful to accelerate vaccine development and testing drug and chemical interactions with the immune system, coupled with disease models to provide a more complete representation of an immune response. | 11-04-2010 |
| 20110171689 | ARTIFICIAL IMMUNE SYSTEM: METHODS FOR MAKING AND USE - The present invention relates to methods of constructing an integrated artificial immune system that comprises appropriate in vitro cellular and tissue constructs or their equivalents to mimic the normal tissues that interact with vaccines in mammals. The artificial immune system can be used to test the efficacy of vaccine candidates in vitro and thus, is useful to accelerate vaccine development and testing drug and chemical interaction with the immune system. | 07-14-2011 |
| 20110250620 | METHODS OF EVALUATING AN IMMUNE RESPONSE TO AN ANTIGEN - The present invention incorporates germinal centers (GCs) into three-dimensional (3D) engineered tissue constructs (ETCs). In an embodiment, we have incorporated the GC in the design of an artificial immune system (AIS) to examine immune responses to vaccines and other compounds. Development of an in vitro GC adds functionality to an AIS, in that it enables generation of an in vitro human humoral response by human B lymphocytes that is accurate and reproducible, without using human subjects. The invention also permits evaluation of, for example, vaccines, allergens, and immunogens, and activation of human B cells specific for a given antigen, which can then be used to generate human antibodies. In an embodiment of the present invention the function of the in vitro GC is enhanced by placing FDCs and other immune cells in a 3D ETC; FDCs appear more effective over a longer time (antibody production is sustained for up to about 14 days. | 10-13-2011 |
| 20110269176 | METHODS FOR ASSAYING RESPONSES TO VACCINES - The present invention incorporates germinal centers (GCs) into three-dimensional (3D) engineered tissue constructs (ETCs). In an embodiment, we have incorporated the GC in the design of an artificial immune system (AIS) to examine immune responses to vaccines and other compounds. Development of an in vitro GC adds functionality to an AIS, in that it enables generation of an in vitro human humoral response by human B lymphocytes that is accurate and reproducible, without using human subjects. The invention also permits evaluation of, for example, vaccines, allergens, and immunogens, and activation of human B cells specific for a given antigen, which can then be used to generate human antibodies. In an embodiment of the present invention the function of the in vitro GC is enhanced by placing FDCs and other immune cells in a 3D ETC; FDCs appear more effective over a longer time (antibody production is sustained for up to about 14 days. | 11-03-2011 |
| 20120009561 | METHODS OF EVALUATING A TEST AGENT IN A DISEASED CELL MODEL - The present invention relates to methods of constructing an integrated artificial immune system that comprises appropriate in vitro cellular and tissue constructs or their equivalents to mimic the tissues of the immune system in mammals. The artificial immune system can be used to test the efficacy of vaccine candidates and other materials in vitro and thus, is useful to accelerate vaccine development and testing drug and chemical interactions with the immune system, coupled with disease models to provide a more complete representation of an immune response. | 01-12-2012 |
Heather Fairhead, Cambridge GB
| Patent application number | Description | Published |
|---|---|---|
| 20100239536 | Modified Bacteriophage Including an Alpha/Beta Small Acid-Soluble Spore Protein (SASP) Gene - Provided is a modified bacteriophage capable of infecting a target bacterium, which bacteriophage includes an α/β small acid-soluble spore protein (SASP) gene encoding a SASP which is toxic to the target bacterium, wherein the SASP gene is under the control of a constitutive promoter which is foreign to the bacteriophage and the SASP gene. | 09-23-2010 |
Heather Ferrea, Tucson, AZ US
| Patent application number | Description | Published |
|---|---|---|
| 20110091897 | COMPOSITIONS COMPRISING NANOMATERIALS AND METHOD FOR USING SUCH COMPOSITIONS FOR HISTOCHEMICAL PROCESSES - Histochemical process compositions comprising at least one nanoparticle in an amount effective to reduce or substantially eliminate the average number of spots per slide that result from a sample staining protocol are disclosed. Various nanoparticles, or combinations thereof, including metals, metal alloys, metal oxides, ceramics, functionalized metals or metalloids, and other miscellaneous nanoparticles, such as carbon nanoparticles and diamond nanoparticles, can be used. The nanoparticle concentration typically is from about 2 parts per million to about 20 parts per million. One embodiment of a disclosed method concerns applying a histochemical process composition to a sample, followed by performing a staining protocol on the sample. Particular embodiments concern dispensing a nanosolution onto a sample using an automated system, heating the sample, and performing a sample staining process. | 04-21-2011 |
Heather Fielder Horton, Nashville, TN US
| Patent application number | Description | Published |
|---|---|---|
| 20110159265 | High Strength and High Elongation Wipes - The present invention provides high strength nonwoven wipe materials and the process of making the materials. The high strength nonwoven wipe materials contain cellulosic fibers, synthetic fibers, or mixtures thereof, with bicomponent fibers and optionally, a binder. The present invention provides a high strength, high elongation, reduced stiffness nonwoven wipe material with superior tensile strength. | 06-30-2011 |
Heather Gornik, Cleveland, OH US
| Patent application number | Description | Published |
|---|---|---|
| 20110040572 | METHOD AND SYSTEM FOR MONITORING AND MANAGING PATIENT CARE - A patient management system includes a patient unit that obtains results data from a patient device and provides for two-way communication between the patient unit and a remote database. The patient unit can communicate with the remote database to obtain encounter instruction data for a given encounter as well as to send response data for the given encounter. A back office system can also access the database to retrieve the patient data for one or more patient users. The back office system can further add or modify encounter instruction data for use during a next encounter at the patient unit. The back office system can also set a dosage for the patient that can be stored in the remote database and retrieved by the patient unit as part of the given encounter. The back office system may also employ a rules engine that can be programmed according to an established protocol and can automatically generate encounter instructions and dosage information for one or more patient. | 02-17-2011 |
Heather Green, Madison, WI US
| Patent application number | Description | Published |
|---|---|---|
| 20100299781 | RESPONSES TO SINGLET OXYGEN - The physiological response of an organism to singlet oxygen is altered by modulating the interaction between an anti-sigma factor, ChrR, and a sigma factor, σ | 11-25-2010 |
Heather Greenstone, Silver Spring, MD US
| Patent application number | Description | Published |
|---|---|---|
| 20090203113 | CHIMERIC PAPILLOMAVIRUS-LIKE PARTICLES - The present invention provides a papillomavirus-like particle, characterized as having conformational epitopes, comprising a papillomavirus L1 product and a papillomavirus L2 fusion product; and related synthetic DNA molecules, host cells, methods and vaccines. | 08-13-2009 |
| 20100172936 | CHIMERIC PAPILLOMAVIRUS-LIKE PARTICLES - The present invention provides a papillomavirus-like particle, characterized as having conformational epitopes, comprising a papillomavirus L1 product and a papillomavirus L2 fusion product; and related synthetic DNA molecules, host cells, methods and vaccines. | 07-08-2010 |
Heather Hane-Karr, Newbury Park, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20100087763 | Hand-held cradle for ball massage - A massage implement is provided that incorporates the use of commonly available golf balls, or other objects of similar dimensions and properties. The massage implement comprises a rigid or semi-rigid housing to hold a golf ball, a cavity to allow such golf ball to move freely within the implement, a comfortable and ergonomically balanced shape, finger impressions for greater control and grip, and other built-in utilities essential to a proper massage and other affiliated uses. | 04-08-2010 |
Heather Himburg, Durham, NC US
| Patent application number | Description | Published |
|---|---|---|
| 20110293574 | Hematopoietic stem cell growth factor - The present invention relates, in general, to stem cells and, in particular, to a hematopoietic stem cell (HSC) growth factor and to methods of using same. | 12-01-2011 |
Heather Hoops, Golden, CO US
| Patent application number | Description | Published |
|---|---|---|
| 20090192389 | INNOVATIVE COMPONENTS FOR AN ULTRASONIC ARC SCANNING APPARATUS - Embodiments of the present invention are directed to various aspects of imaging systems, including permeable and impermeable barriers separating liquid compartments, one of which contains the object to be imaged and the other an ultrasonic transducer, a fluidic bearing between a transducer carriage and guide supporting the carriage, a linear motor for the carriage, and a location sensing device for the carriage. | 07-30-2009 |
Heather Huot Creasy, Gaithersburg, MD US
| Patent application number | Description | Published |
|---|---|---|
| 20120070457 | Polypeptides from neisseria meningitidis - Polypeptides comprising | 03-22-2012 |
Heather Kobzan, Pickering CA
| Patent application number | Description | Published |
|---|---|---|
| 20110131721 | BATHTUB BACK SUPPORT SYSTEMS - A back rest device for a bathtub comprising a rest member having a front surface and a back surface, at least one suction cup, a cover with pockets, and at least one insertable pillow. The rest member is placed against a bathtub back and on a cushioned bathmat that suctions to the floor of the bathtub. The suction cups are attached to the back surface of the rest member to facilitate the attachment of the rest member to the bathtub back. The cover with pockets is attached to the front surface of the rest member and the insertable pillow is placed inside the pockets to create additional comfort. | 06-09-2011 |
Heather Konet, Canton, MI US
| Patent application number | Description | Published |
|---|---|---|
| 20090318069 | CONTACT-FREE VEHICLE AIR VENT - A contact-free air vent flow direction control device includes an air vent, a positioning mechanism, a touch-less motion sensor and a control unit. The air vent has at least one flow control blade configured to move between a plurality of predetermined orientations each corresponding to a direction of air flow from the air vent. The positioning mechanism is operably coupled to the flow control blade. The touch-less motion sensor is configured to detect relative movement of objects proximate the touch-less motion sensor. The control unit is operably connected to the touch-less motion sensor and the positioning mechanism to control operation of the positioning mechanism in order to position the flow control blade in a selected one of the predetermined orientations in response to a corresponding one of a plurality of predetermined movements detected by the touch-less motion sensor. | 12-24-2009 |
| 20120068836 | SYSTEM AND METHOD FOR PRODUCING AN AUDIBLE ALERT FOR A VEHICLE - A method for controlling a vehicle to emanate an audible alert. The method includes determining when the vehicle is operating, and controlling a speaker system in the vehicle to emanate the audible alert outside of the vehicle for a period of time when the vehicle is operating. The audible alert has a sound profile that includes a simultaneous emanation of a first audible frequency component at a first sound pressure level and a second audible frequency component at a second sound pressure level, with the first and second sound pressure levels being greater than a sound pressure level of the sound profile at all other frequencies. The method further includes modulating the first sound pressure level of the first audible frequency component. | 03-22-2012 |
Heather Koshinsky, El Cerrito, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20080220436 | METHODS AND COMPOSITIONS FOR RAPID LIGHT-ACTIVATED ISOLATION AND DETECTION OF ANALYTES - The present invention relates to novel methods for isolating a target molecule from a sample suspected of containing the target molecule. The methods of the present invention utilize solid substrates as a means for capturing, separating, and releasing target molecules, such as chemical or biological compounds. The present invention is specifically directed to novel approaches for capturing, separating and releasing such target molecules. | 09-11-2008 |
| 20100049445 | METHOD AND APPARATUS FOR SEQUENCING DATA SAMPLES - A method for identifying non-host nucleic acid sequence using sequence data. The method of identifying non-host nucleic acid can include sequencing a sample into sequences and associating the sequences with a host genome and then exclude any sequences that are associated with the host genome. The method can then associate the sequences with any known genomes and exclude any sequences that are associated with any known genome. The remaining sequences can be used as seed sequences to assemble a non-host nucleic acid. | 02-25-2010 |
| 20100209909 | ASSAYS BASED ON DETECTION OF PHOTOBLEACHING REACTION PRODUCTS FROM DYE CATALYTIC COMPLEX - The present invention relates to the methods for assaying an analyte comprising a nucleic acid analog binding substrate in a sample, comprising reacting a catalytic complex comprising a nucleic acid analog, a nucleic acid analog specific binding substrate and a light reactive dye with a light stimulus, and detecting the presence or absence or amount of a reaction product of the catalytic complex and light stimulus. The present invention also relates to a method of assaying a nucleic acid analyte in a sample using an analyte-specific reporter complex. The present invention also relates to a method of assaying an analyte in a sample using a reporter molecule. | 08-19-2010 |
| 20110008905 | SYSTEM FOR DETECTING POLYNUCLEOTIDES - The present invention relates to methods for detecting the presence or amount of a target polynucleotide. A polynucleotide, target nucleic acid analog, and dye are combined to form a mixture. The optical property of the dye is observed after the mixture is exposed to a stimulating means. Optionally, after the stimulating means is employed, the mixture is compared to a reference value characteristic of the rate of change in the optical property of the dye in a similar mixture containing a known amount of a target polynucleotide/nucleic acid analog hybrid to determine a relative rate of change in the optical property. The change in a property of the mixture after exposure thereof to a stimulating means or the relative rate of change in the optical property of dye in the mixture is correlated with the presence or amount of the specified target polynucleotide in the sample. | 01-13-2011 |
Heather Lane-Brown, Honeoye Falls, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20090176247 | Determination of sFlt-1:Angiogenic Factor Complex - Methods for determining the presence or amount of a complex comprising a first and second molecular entity are provided, preferably an sFlt-1:PlGF complex. A determination of the presence or amount of the complex can be used in methods for predicting, detecting, monitoring a disease, or guiding therapy in respect to a disease such as vascular, vascular-related disease, cardiac, cardiac-related disease, cancer, cancer-related disease, preeclampsia, and preeclampsia-related disease. Determining sFlt- | 07-09-2009 |
Heather Lindenman, Germantown, TN US
| Patent application number | Description | Published |
|---|---|---|
| 20110301650 | ADJSUTABLE BONE ANCHOR ASEMBLY - A medical implant device has in one embodiment a receiver member for receiving an elongated member, a crown member, an anchor member and a retaining member. An embodiment of the receiver member has an axial opening, a transverse channel, a chamber including at least one substantially flat wall, and a groove. An embodiment of the crown member has at least one substantially flat side. An embodiment of the anchor member has a head with at least one substantially flat surface that may be parallel to the anchor member's longitudinal axis, and an anchoring portion. An embodiment of the retaining member is a substantially flat clip. The crown member and anchor member are inserted into the chamber, and the retaining member is inserted into the groove beneath them. The anchor member may be pivoted substantially in one plane with respect to the receiver member until locked. | 12-08-2011 |
Heather Lindenman, Otterbein, IN US
| Patent application number | Description | Published |
|---|---|---|
| 20110106164 | APPARATUS FOR IMPLEMENTING A SPINAL FIXATION SYSTEM WITH SUPPLEMENTAL FIXATION - An apparatus for implementing a spinal fixation system with supplemental fixation includes a spinal fixation rod assembly and at least one supplemental fixation device. The spinal fixation rod assembly is adapted to provide primary fixation at a plurality of first fixation points by being secured to a plurality of first vertebral components except not into one of the first vertebral components of the plurality that is in a weakened structural condition and located between other of the first vertebral components of the plurality. The supplemental fixation device is adapted to provide supplemental fixation for the assembly at a second fixation point by being secured to a second vertebral component located adjacent to and offset from the one first vertebral component in the weakened structural condition and also to interconnect with the assembly to provide anchorage and thus additional fixation supplemental to the primary fixation. | 05-05-2011 |
Heather Lossing, Hamilton CA
| Patent application number | Description | Published |
|---|---|---|
| 20100126929 | MEMBRANE SUPPORTED BIOFILM APPARATUS AND PROCESS - A membrane supported biofilm apparatus has a plurality of hollow fiber gas permeable membranes in a tank containing water to be treated. The membranes have an outside diameter of about 200 microns or less and occupy between 0.5% and 4% of the tank volume. A biofilm supported on the membranes occupies between about 40% and 80% of the volume of water to be treated in a reactor. The membranes may be oriented generally vertically and a spreader may be located near the bottom of the apparatus to disperse the membranes. Wastewater treatment processes are described. A process to dentrify water or treat oxidized contaminants comprises introducing hydrogen into an inner volume of the membranes to grow autotrophic organisms in the biofilm near the membrane and heterotrophic organism near the water. Another process is operated at a biomass concentration of at least 10 g/L and up to about 40 g/L to maintain a biofilm having a surface area of over 1000 square metres per cubic metre of tank volume. A hybrid process has suspended biomass and a membrane supported biofilm. | 05-27-2010 |
Heather Maecker, Palo Alto, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20080286271 | Methods and Compositions for Modulating Tweak and Fn14 Activity - Agonists and antagonists which modulate the activity of TWEAK and TWEAK receptor are provided. The methods, compositions and kits of the invention may be employed in the treatment of disorders such as cancer and immune-related diseases. | 11-20-2008 |
| 20100203056 | ANTI-PD-L1 ANTIBODIES AND THEIR USE TO ENHANCE T-CELL FUNCTION - The present application relates to anti-PD-L1 antibodies, nucleic acid encoding the same, therapeutic compositions thereof, and their use enhance T-cell function to upregulate cell-mediated immune responses and for the treatment of T cell dysfunctional disorders, including infection (e.g., acute and chronic) and tumor immunity. | 08-12-2010 |
Heather Mccallum-Bayliss, Mclean, VA US
| Patent application number | Description | Published |
|---|---|---|
| 20080312909 | SYSTEM FOR ADAPTIVE MULTI-CULTURAL SEARCHING AND MATCHING OF PERSONAL NAMES - An automated name searching system incorporates an automatic name classifier and a multi-path architecture in which different algorithms are applied based on cultural identity of the query name. The name classifier operates with a preemptive list, analysis of morphological elements, length, and linguistic rules. A name regularizer produces a character based computational representation of the name. A pronunciation equivalent representation such as an IPA language representation, and language specific rules to generate name searching keys, are used in a first pass to eliminate database entries which are obviously not matches for the query name. The methods can also be implemented as a callable set of library routines including an intelligent preprocessor and a name evaluator that produces a score comparing a query name and database name, based on a variety of user-adjustable parameters. The user-controlled parameters permit tuning of the search methodologies for specific custom applications. | 12-18-2008 |
Heather Mccrabb, Kettering, OH US
| Patent application number | Description | Published |
|---|---|---|
| 20110017608 | ELECTROCHEMICAL ETCHING AND POLISHING OF CONDUCTIVE SUBSTRATES - A method for electrochemically etching a metal layer through an etch-resist layer pattern using a non-active electrolyte solution is described. The method is particularly useful in fabrication of advanced fuel delivery systems for land-based power generation turbines and aerospace turbine engines; of components for advanced thermal management in aerospace electronic devices and in cooling channels; of stents used in medicine; and of microchannels for sensors, chemical reactors, and dialysis and the like. In one embodiment of the invention the metal layer is copper and the non-active electrolyte solution is a mixture of sodium nitrate and sodium chloride and a pulse electric current is employed to accomplish the electrochemical etching. | 01-27-2011 |
| 20120091000 | ELECTROLYTIC SYSTEM AND METHOD FOR FILTERING AN AQUEOUS PARTICULATE SUSPENSION - An electrolytic filtration method and apparatus for the concentration and collection of suspended particulates from aqueous solutions is disclosed. The electrolytic cell contains at least an anode and a cathode, and in one embodiment contains a plurality of anodes and cathodes. The electrolytic cell also contains a filter, and in one embodiment the filter is a moving belt filter. While not bound by theory, the electrolytic filtration method and apparatus is based on the electrophoretic movement of algae particles suspended in an aqueous solution away from the filter under the influence of an electric field. In one embodiment the electric field is a pulsed waveform with unidirectional voltage or current pulses. In another embodiment, the electric field is a pulsed waveform with bidirectional voltage or current pulses. | 04-19-2012 |
Heather Mcfelea, Tempe, AZ US
| Patent application number | Description | Published |
|---|---|---|
| 20120085400 | METHODS OF FABRICATING SEMICONDUCTOR STRUCTURES AND DEVICES USING QUANTUM DOT STRUCTURES AND RELATED STRUCTURES - Methods of fabricating photovoltaic devices include forming a plurality of subcells in a vertically stacked arrangement on the semiconductor material, each of the subcells being formed at a different temperature than an adjacent subcell such that the adjacent subcells have differing effective band-gaps. The methods of fabricating also include inverting the structure, attaching another substrate to the second semiconductor material, and removing the substrate. For example, each of the subcells may comprise a III-nitride material, and each subsequent subcell may include an indium content different than the adjacent subcell. Novel structures may be formed using such methods. | 04-12-2012 |
Heather Messal, Marina Del Rey, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20110226828 | PERSONAL ITEM CARRIER - An exercise harness for wearing by a user, including a front piece; a back piece; two shoulder straps a first shoulder strap configured to attach between the front piece and the back piece over the user's left shoulder and a second strap configured to attach between the front piece and the back piece over the user's right shoulder; a chest strap coupled from below to the front piece and the back piece and configured to surround the body of the user and prevent movement of the front piece and back piece during activity of the user; and wherein the front piece and the back piece both include pockets and wherein the length of the straps are designed to position the front piece and the back piece above the waist of the user at about the center of gravity of the user. | 09-22-2011 |
Heather Patisaul, Cary, NC US
| Patent application number | Description | Published |
|---|---|---|
| 20110194679 | Communication Ranking and Organization - Methods and apparatuses are disclosed herein for organizing communication information. Data received associated with a communication is recorded at the communication device. An identifier is associated with the communication. The identifier indicates a unique identity. A call score is calculated for the identifier at the communication device based on the communication. The particular identifier is ranked in a list in accordance with the calculated call score. | 08-11-2011 |
Heather Prattas, Surfside, FL US
| Patent application number | Description | Published |
|---|---|---|
| 20090212083 | DEVICE HOLDER OF A TRANSPORT APPARATUS - A device holder for a transport apparatus having a user storage compartment which includes a main body detachably coupled to the transport apparatus and a device storage compartment disposed on the main body to store a device therein, wherein the main body is coupled to the transport apparatus to provide a line of sight to a user disposed in the user storage compartment. | 08-27-2009 |
Heather Raymon, San Diego, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20090270418 | PYRAZOLE PYRAZINE AMINE COMPOUNDS AS KINASE INHIBITORS, COMPOSITIONS THEREOF AND METHODS OF TREATMENT THEREWITH - Provided herein are Pyrazole Pyrazine Amine Compounds having the following structure: | 10-29-2009 |
| 20120129807 | METHODS OF TREATMENT, IMPROVEMENT AND PREVENTION USING HALOARYL SUBSTITUTED AMINOPURINES - Provided herein are Aminopurine Compounds having the following structure: | 05-24-2012 |
Heather Rohllf, Clifton, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20110305547 | Retractable Tool for Collecting Craft Objects - A retractable herding apparatus comprises a housing, a tap drum, a retractable tape, and a biasing member. The housing has an interior cavity, a sidewall and an opening defined in the sidewall to provide access into the cavity. The tape drum is rotatably disposed in the housing. The retractable tape has a first end and a second end. The first end of the retractable tape is attached to the tape drum. The second end of the retractable tape is attached to the housing proximate the opening in the sidewall. The retractable tape is movable between a fully retracted position and a fully protracted position. The biasing member couples to the tape drum. The biasing member is provided to bias the retractable tape toward the retracted position. | 12-15-2011 |
Heather Savage-Erickson, Memphis, TN US
| Patent application number | Description | Published |
|---|---|---|
| 20100262244 | Metal Coated Implant - A metal coated implant and a method for using the implant for expanding an intervertebral disc space is provided. The implant comprises a polymer substrate and a metallic coating layer wherein the metallic coating layer is attached to the polymer substrate. There metal coated implant further comprising a biocompatible radiolucent polyetheretherketone (PEEK) material, and a metallic coating layer that is a titanium (Ti) or gold (Au) material. The metal coated implant's radiolucent and radiopaque properties enhance a surgeon's ability to distinctly visualize the metal coated implant to thereby better control and maneuver the delivery, insertion, trajectory, position and orientation of the metal coated implant through the patient anatomical environment and into the vertebral disc space. | 10-14-2010 |
Heather Schenck Mortell, Neenah, WI US
| Patent application number | Description | Published |
|---|---|---|
| 20090217442 | PROCESS TO MAKE BOXER SHORTS HAVING A CONTRACTED CROTCH REGION - A pant has a garment shell. The garment shell includes a front region, a back region, a contracted crotch region, side seams connecting the front region to the back region, two leg openings, and hanging legs. At least a portion of each of the front region, the back region, the contracted crotch region and the hanging legs include portions of a single flat web. The hanging legs include no elasticization around a full periphery of the leg openings and are adapted to hang loosely about a wearer's thigh. | 09-03-2009 |
Heather Schmidt, Santa Rosa, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20120083153 | MULTIFUNCTIONAL ACCESSORIES FOR MOBILE DEVICES - A multifunctional accessory for a mobile device, in one example embodiment, comprises an anterior assembly, which includes a plurality of sides and an anterior aperture for viewing and providing access to the mobile device, with the plurality of anterior sides and the anterior aperture forming an anterior recess. The accessory further comprises a posterior assembly including a plurality of posterior sides and a posterior panel, with the plurality of posterior sides and the posterior panel forming a posterior recess, wherein the anterior and posterior recesses accommodate the mobile device. The accessory further comprises a hinge assembly to pivotally couple the anterior assembly and the posterior assembly at one or more of the plurality of anterior sides and the plurality of posterior sides, with the hinge assembly allowing the anterior assembly and the posterior assembly to pivot about each other along one or more edge axes securing the mobile device at an adjustable viewing angle. | 04-05-2012 |
Heather Twin US
| Patent application number | Description | Published |
|---|---|---|
| 20120136000 | TRI-CYCLIC PYRAZOLOPYRIDINE KINASE INHIBITORS - The present invention relates to compounds useful as inhibitors of protein kinase. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders. The invention also provides processes for preparing compounds of the inventions. | 05-31-2012 |
Heather Twin, Denchworth GB
| Patent application number | Description | Published |
|---|---|---|
| 20090291937 | KINASE INHIBITORS - The present invention relates to compounds useful as inhibitors of protein kinase. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders. The invention also provides processes for preparing compounds of the inventions. | 11-26-2009 |
Heather Twin, Wantage GB
| Patent application number | Description | Published |
|---|---|---|
| 20100190765 | DIHYDRODIAZEPINES USEFUL AS INHIBITORS OF PROTEIN KINASES - The present invention relates to compounds useful as inhibitors of protein kinase. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders. The invention also provides processes for preparing compounds of the inventions. | 07-29-2010 |
| 20120071494 | PYRAZOLOPYRIDINE KINASE INHIBITORS - The present invention relates to compounds useful as inhibitors of protein kinase. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders. The invention also provides processes for preparing compounds of the inventions. | 03-22-2012 |
Heather Wighton, Flemington, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20120101817 | SYSTEM AND METHOD FOR GENERATING MODELS FOR USE IN AUTOMATIC SPEECH RECOGNITION - Disclosed herein are systems, methods, and non-transitory computer-readable storage media for generating a model for use with automatic speech recognition. These principles can be implemented as part of a streamlined tool for automatic training and tuning of speech, or other, models with a fast turnaround and with limited human involvement. A system configured to practice the method receives, as part of a request to generate a model, input data and a seed model. The system receives a cost function indicating accuracy and at least one of speed and memory usage, The system processes the input data based on seed model and based on parameters that optimize the cost function to yield an updated model, and outputs the updated model. | 04-26-2012 |