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| 20090068690 | METHODS FOR IDENTIFYING PATIENTS WITH AN INCREASED LIKELIHOOD OF HAVING OVARIAN CANCER AND COMPOSITIONS THEREFOR - Screening methods for identifying patients with an increased likelihood of having ovarian cancer are provided. The screening methods involve the detection of expression of a plurality of biomarkers in a body sample, wherein overexpression of the biomarkers is indicative of an increased likelihood of having ovarian cancer. The screening methods may further comprise a two-step analysis. Biomarkers of interest include genes and proteins that are, for example, involved in defects in DNA replication/cell cycle control, cell growth and proliferation, escape from apoptosis, angiogenesis or lymphogenesis, or the mechanisms of cancer cell motility and invasion. In some aspects of the invention, expression of a biomarker is detected at the protein level using a biomarker-specific antibody or at the nucleic acid level using nucleic acid hybridization techniques. Methods for detecting ovarian cancer in patients are further disclosed herein. Kits for practicing the methods of the invention are further provided. | 03-12-2009 |
| 20090075307 | METHODS FOR IDENTIFYING PATIENTS WITH AN INCREASED LIKELIHOOD OF HAVING OVARIAN CANCER AND COMPOSITIONS THEREFOR - Screening methods for identifying patients with an increased likelihood of having ovarian cancer are provided. The screening methods involve the detection of expression of a plurality of biomarkers in a body sample, wherein overexpression of the biomarkers is indicative of an increased likelihood of having ovarian cancer. The screening methods may further comprise a two-step analysis. Biomarkers of interest include genes and proteins that are, for example, involved in defects in DNA replication/cell cycle control, cell growth and proliferation, escape from apoptosis, angiogenesis or lymphogenesis, or the mechanisms of cancer cell motility and invasion. In some aspects of the invention, expression of a biomarker is detected at the protein level using a biomarker-specific antibody or at the nucleic acid level using nucleic acid hybridization techniques. Methods for detecting ovarian cancer in patients are further disclosed herein. Kits for practicing the methods of the invention are further provided. | 03-19-2009 |
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| 20100005898 | System and method for conditioning and detection of moisture damage in asphalt mixes - An apparatus and method for determination of susceptibility of asphalt concrete materials to moisture damage. An asphalt sample of known bulk specific gravity (density) is placed inside a chamber filled with water, which is capable of heating the sample to a pre-determined temperature. The chamber is pressurized by introduction of air pressure to a flexible membrane that decreases the volume within a chamber containing the sample and water, increasing the pore pressure in the sample. The pressure is then released and allowed to come to ambient pressure. This process is repeated a predetermined number of times (cycles). When a selected number of cycles are complete, the asphalt sample is removed from the chamber and its bulk specific gravity (density) measured again. The difference between the density before and after conditioning is an excellent method of rating the degree at which moisture would deteriorate asphalt samples due to introduction of moisture. The cyclic nature of the increased/decreased pore pressure is observed to significantly decrease bulk specific gravity (density) for poor quality asphalt designs. Furthermore, the sample conditioned by this method can be used for other conventional mechanical test methods, such as tensile strength and modulus determination. Computerized controls are used to automate the procedure and to record and display data from sensors. | 01-14-2010 |
| 20100319211 | Device and Methods for Rapid Drying of Porous Materials - An apparatus and method for quickly drying porous materials. A sealable chamber is connected to a cold trap which is connected to a vacuum pump. A sample is placed inside the sealable chamber. The vacuum pump is turned on and air is evacuated through the cold trap to the vacuum pump. Because evaporation may lower the temperature inside the sealable chamber, an infrared lamp may be used to heat the chamber and sample therein directly or heated air may be allowed to enter the sealable chamber in response to the vacuum created by the vacuum pump. Air may be drawn directly from the sealable chamber to the vacuum pump bypassing the cold trap. A load cell may be placed in the bottom of the sealable chamber to monitor the weight of a sample to determine if the drying process is complete. Other parameters could be used, including the degree of vacuum achieved in the chamber. The cold trap extracts moisture from the system, which eliminates the possibility of damage to the vacuum and creates an added pressure gradient for removal of air from the sealable chamber. Heating the chamber either by introducing heated air or by direct use of infrared heat facilitates drying of the sample and shortens the drying process. | 12-23-2010 |
| 20110214484 | System and Method for Conditioning and Detection of Susceptibility to Moisture Damage in Asphalt Mixes - An apparatus and method for determination of susceptibility of asphalt concrete materials to moisture damage. An asphalt sample of known bulk specific gravity (density) is placed inside a chamber filled with water, which is capable of heating the sample to a predetermined temperature. The chamber is pressurized by introduction of air pressure to a flexible membrane that decreases the volume within a chamber containing the sample and water, increasing the pore pressure in the sample. The pressure is then released and allowed to come to ambient pressure. This process is repeated a predetermined number of times (cycles). When a selected number of cycles are complete, the asphalt sample is removed from the chamber and its bulk specific gravity (density) measured again. The difference between the density before and after conditioning is an excellent method of rating the degree at which moisture would deteriorate asphalt samples due to introduction of moisture. The cyclic nature of the increased/decreased pore pressure is observed to significantly decrease bulk specific gravity (density) for poor quality asphalt designs. Furthermore, the sample conditioned by this method can be used for other conventional mechanical test methods, such as tensile strength and modulus determination. Computerized controls are used to automate the procedure and to record and display data from sensors. | 09-08-2011 |
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| 20080283593 | Compromised Account Detection - Systems and methods are disclosed for identifying a compromised account. A compromised account may be identified by identifying a first unique identifier and associating the unique identifier with a fraud behavior. A second unique identifier may be identified and associated with a fraud behavior as well. The first unique identifier and the second unique identifier may be linked if at least a portion of the fraud behavior of the first unique identifier corresponds to at least a portion of the fraud behavior of the second unique identifier. Information relating to the fraud behavior of the first unique identifier, information relating to the fraud behavior of the second unique identifier, and information relating to the link between the fraud behavior of the first unique identifier and the second unique identifier may be stored in a data file. The first and/or the second unique identifiers may be an Internet protocol address. | 11-20-2008 |
| 20090030756 | Managing Risk Associated with Various Transactions - Systems, methods and consumer-readable media for managing risk associated with various transactions are provided. Such methods may include identifying a consumer-based software application for analysis and classifying the consumer-based software application into a plurality of consumer-facing transactions. Each consumer-facing transaction may be rated according to at least one category or criteria. Further, each rating may be converted into a numeric value. Another aspect of the invention may relate to receiving an identification of a list of threats to each of the consumer-facing transactions. These threats may be categorized into threat categories. The impact of each of the threats may be forecasted. The overall impact of the threats as forecasted may be calculated. Yet another aspect of the invention may relate to receiving an identification of a plurality of threat controls that control at least a portion of the plurality of threats. | 01-29-2009 |
| 20110087495 | SUSPICIOUS ENTITY INVESTIGATION AND RELATED MONITORING IN A BUSINESS ENTERPRISE ENVIRONMENT - Systems, methods, and computer program products are provided for monitoring of financial institution business activity for the purpose of identifying suspicious activities. The embodiments herein described rely on monitoring business activities from many data repositories, some of which are exclusive to financial institution. By monitoring financial business activity for the purpose of identifying suspicious activity or behaviors, bank fraud or other criminal/wrongful activities can be mitigated or otherwise avoided. In addition, the identification of suspicious activities serves to identify the individual(s) associated with the suspicious activities and/or other information related to the individual(s), such as physical location, electronic location, telephone number and the like. | 04-14-2011 |
