Haydee
Haydee Blanco Fuente, Las Arenas ES
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20100004285 | POLYMORPH OF 4-[2-[4-[1-(2-ETHOXYETHYL)-1H-BENZIMIDAZOLE-2-YL]-1-PIPERIDINYL]ETHYL]-al- pha alpha-DIMETHYL-BENZENEACETIC ACID - Crystalline form 1 4-[2-[4-[1 -(2-ethoxyethyl)-1H-benzimidazole-2-yl]-1-piperidinyl]-ethyl]-αα-dimethyl-benzeneacetic acid of formula (I) is described, procedures for its preparation, pharmaceutical formulae containing crystalline form 1 and the use of crystalline form 1 to treat allergic reactions and pathological processes mediated by histamine in mammals such as man. | 01-07-2010 |
Haydee De Clippeleir, Hamme BE
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20140083936 | METHOD AND APPARATUS FOR WATER TREATMENT USING SCREENS - An apparatus and method for selecting, retaining or bioaugmenting solids in an activated sludge process for improving wastewater treatment using screens. The screens can be used to separate and retain solids based on size, compressibility or shear resistance. The screens are used to separate and select slow growing organisms, faster settling organisms, or materials added to absorb, treat or remove constituents in the activated sludge process. A swapping screen arrangement provides another means of selecting various particles. The exposed shear rate or time, particle compression, or SRTs can be adjusted manually and/or automatically in response to detected readings from an instrument such as a spectrophotometer or other optical approaches to optimize selection of organisms. The present disclosure may be configured as an activated sludge system operated at different solids residence times (SRT) for different solids fractions allowing slow growing organisms to get established in competition with faster growing organisms or aggregates thereof. | 03-27-2014 |
Haydee De Clippeleir, Washington, DC US
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20150376043 | METHOD AND APPARATUS FOR WASTEWATER TREATMENT USING EXTERNAL SELECTION - A method and an apparatus for biological wastewater treatment that includes a biological selector and a physical selector. The apparatus comprises an internal biological reactor where wastewater and recycled biomass are combined to provide a high substrate and high electron acceptor gradient for generating morphological biomass features that favor granule formation over floc and filament formation, and an external gravimetric or external screen selector operating on the biomass waste stream for collecting and retaining densified biomass aggregates including dense granule selection and for wasting lighter filaments and flocs. In the method and apparatus, particles may be added to provide cores to promote the formation of aggregates encapsulating the seeded particles. The particles may be added as various materials, for example, in the bioreactor, to initiate or seed the formation of a granule, that could then be separated by or integrated with either the external gravimetric or external screen selector. Further, organisms may be selected for biological phosphorus removal, denitrifying methane oxidizers, biological sulfur or sulfide oxidation, methanogenesis. | 12-31-2015 |
Haydee Geronimo Perez, Ciudad De La Habana CU
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20080312139 | Use of Pharmaceutical Composition Containing Epidermal Growth Factor (EGF) for Diabetic foot Amputation Prevention - The invention relates to the use of Epidermal Growth Factor (EGF) in a preferably-Injectable pharmaceutical composition which is administered by means of infiltration into and around chronic cutaneous ischaemic lesions in order to prevent diabetic foot amputation. Said composition can be administered to recently-created surgical surfaces damaged by the effect of acute reperfusion with oxygenated blood following prolonged ischaemia, thereby preventing further surgical procedures and favouring the preservation of the extremity. The aforementioned composition can be used to improve (i) the cell microenvironment, thereby increasing the reparative and defensive capacity and viability of the is tissues and (ii) the cicatrisation of cutaneous ischaemic lesions, thereby stimulating cell proliferation. The invention is suitable for use in human, veterinary and experimental medicine, specifically in vascular angiology and surgery, dermatology, burn treatment and reconstructive surgery and geriatric medicine. Said composition can be used for recalcitrant ulcers which are associated with lesions in the macro and/or microvasculature, patients with inadequate lymphatic and/or venous return and ulcers or other lesions which are difficult to cicatrise and/or heal. | 12-18-2008 |
20090136511 | Interleukin-15 Antagonist Peptide - Current invention is related to the molecular pharmacology branch particularly to a peptide belonging to the Interleukin-15 sequence (IL-15) which is able to inhibit IL-15 biological activity, analogues or mimetic of such peptides. In the current invention it is shown that the peptide inhibits both IL-15-induced T cells proliferation upon binding to the IL15 receptor α subunit (IL15Rα) and TNFα-mediated apoptosis. | 05-28-2009 |
20110251140 | PEPTIDE ANTAGONIST OF INTERLEUKIN-15 ACTIVITY - The present invention is related to the field of molecular immunology, particularly to a peptide derived from the sequence of interleukine-15 (IL-15), wherein said peptide was optimized to inhibit the biological activity of this molecule. In the present invention, it is shown that this peptide inhibits IL-15-induced T cell proliferation, Tumor Necrosis Factor α (TNFα) induction and the expression of IL-8 and IL-6 by the IL-15 receptor a subunit (IL-15Rα), all these effects mediated by the binding of the peptide to the IL-15Rα. The invention is also related to the use of the peptide to treat pathologies where the abnormal expression of IL-15 or IL-15Rα is related to the course of the disease, such as rheumatoid arthritis (RA) and prostate cancer. | 10-13-2011 |
Haydee Martorell Pena, St. Andrew De Llavaneres ES
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20110108579 | PUMP RETENTION COLLAR AND METHODS FOR USING THE SAME - A pump retention collar for assembling a pump on a bottle may be made of a plastic or resin material and may be configured to fit any number of pump sizes, bottle sizes, or bottle neck finishes such that one collar may be used interchangeably with numerous production configurations. | 05-12-2011 |