Patent application number | Description | Published |
20120245137 | ARYL SULPHONE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS - Methods and compounds effective in ameliorating conditions characterized by unwanted calcium channel activity, particularly unwanted N-type and/or T-type calcium channel activity, are disclosed. Specifically, a series of compounds containing aryl sulphone derivatives, as exemplified by Formula (I). | 09-27-2012 |
20130065926 | N-PIPERIDINYL ACETAMIDE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS - Methods and compounds effective in ameliorating conditions characterized by unwanted calcium channel activity, particularly unwanted T-type calcium channel activity are disclosed. Specifically, a series of compounds containing N-piperidinyl acetamide derivatives as shown in formula (1). | 03-14-2013 |
20140113898 | BISARYLSULFONE AND DIALKYLARYLSULFONE COMPOUNDS AS CALCIUM CHANNEL BLOCKERS - The invention relates to bisarylsulfone and dialkylarylsulfone compounds (e.g., compounds according to any of Formulas (I)-(IX) or compounds (1)-(227) of Tables 4 and 5) useful in treating conditions associated with calcium channel function, and particularly conditions associated with N-type calcium channel activity. The invention also relates to pharmaceutical compositions that include these bisarylsulfone compounds, as well methods for the treatment of conditions such as cardiovascular disease, epilepsy, cancer and pain. | 04-24-2014 |
Patent application number | Description | Published |
20120078930 | FRAMEWORK FOR EXTREMELY LARGE COMPLEX OBJECTS (XLCOS) - Provided are techniques for receiving multiple data streams having different data formats. The multiple data streams are converted into an Extremely Large Complex Object (XLCO) file by forming multiple XLCO segments corresponding to the multiple data streams, wherein different data formats are stored in different XLCO segments, and wherein different XLCO segments are different sizes. The XLCO segments of the XLCO are stored in different physical file systems having different operating systems. | 03-29-2012 |
20120297254 | ON DEMAND TRACING OF APPLICATION CODE EXECUTION - On demand tracing of application code execution includes: during the execution of the application code, writing trace statements to a circular trace buffer (at a selected and potentially variable detail level); determining whether a pre-defined trigger event has occurred; in response to determining that the trigger event has occurred, outputting one or more trace statements in the circular trace buffer according to pre-defined trace parameters; determining whether a trigger end event has occurred; and in response to determining that the trigger end event has occurred, terminating the outputting of the trace statements. The trigger event and the trigger end event may be defined by names of application code variables, values for the variables, and operators to be used. The trigger end event may further be defined by a time duration for which trace statements are to be outputted, or a number of trace statements to be outputted. | 11-22-2012 |
20130232381 | ON DEMAND TRACING OF APPLICATION CODE EXECUTION - On demand tracing of application code execution includes: during the execution of the application code, writing trace statements to a circular trace buffer (at a selected and potentially variable detail level); determining whether a pre-defined trigger event has occurred; in response to determining that the trigger event has occurred, outputting one or more trace statements in the circular trace buffer according to pre-defined trace parameters; determining whether a trigger end event has occurred; and in response to determining that the trigger end event has occurred, terminating the outputting of the trace statements. The trigger event and the trigger end event may be defined by names of application code variables, values for the variables, and operators to be used. The trigger end event may further be defined by a time duration for which trace statements are to be outputted, or a number of trace statements to be outputted. | 09-05-2013 |