Hartman, PA
Dorothy M. Hartman, Philadelphia, PA US
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20100005967 | METHOD TO SCRUB GREENHOUSE GASES FROM THE ATMOSPHERE - Carbon dioxide, methane, nitrous oxide and three groups of fluorinated gases have been referred to as greenhouse gases and the most offensive gases in contributing to Global Warming This invention comprises the use of Titration and other chemical oxidation—reduction reactions in novel ways to scrub these gases from the Earth's atmosphere. The invention comprises identifying, developing, and spraying base aerosols to neutralize carbon dioxide, nitrous oxide, sulphur dioxide, and similar compounds whose oxides form acids when dissolved in water vapor. Acid-base titrations result in neutralization of the acid and the base. The formation of a salt and water typically are by-products. Salt precipitates such as CACO3—calcium carbonate or limestone settle into the oceans naturally forming limestone deposits which act as homes for microscopic sea life. Carbonic acid which results from CO2 being dissolved in water produces calcium carbonate when treated with a base. The invention proposes that by trials other natural salts may be identified which may safely be precipitated to the earth as it is important that the absorption into the Earth's environment occur with a minimum of deleterious effects. There exists a number of acids and The invention further comprises the novel use of vehicles such as space shuttles or a space station as delivery vehicles. | 01-14-2010 |
George D. Hartman, Landsdale, PA US
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20150132258 | AZEPANE DERIVATIVES AND METHODS OF TREATING HEPATITIS B INFECTIONS - Provided herein are compounds useful for the treatment of HBV infection in a subject in need thereof, pharmaceutical compositions thereof, and methods of inhibiting, suppressing, or preventing HBV infection in the subject. | 05-14-2015 |
George D. Hartman, Lansdale, PA US
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20080207693 | Mitotic Kinesin Inhibitors - The present invention relates to dihydropyrazole compounds that are useful for treating cellular proliferative diseases, for treating disorders associated with KSP kinesin activity, and for inhibiting KSP kinesin. The invention also related to compositions which comprise these compounds, and methods of using them to treat cancer in mammals. | 08-28-2008 |
20080274107 | Tyrosine kinase inhibitors - The present invention relates to compounds which inhibit, regulate and/or modulate tyrosine kinase signal transduction, compositions which contain these compounds, and methods of using them to treat tyrosine kinase-dependent diseases and conditions, such as angiogenesis, cancer, tumor growth, atherosclerosis, age related macular degeneration, diabetic retinopathy, inflammatory diseases, and the like in mammals. | 11-06-2008 |
20080287414 | Mitotic Kinesin Inhibitors - The present invention relates to tricyclic pyrazoles according to Formula (I) that are useful for treating cellular proliferative diseases, for treating disorders associated with KSP kinesin activity, and for inhibiting KSP kinesin. The invention also relates to compositions which comprise these compounds, and methods of using them to treat cancer in mammals. | 11-20-2008 |
20090005418 | Mitotic Kinesin Inhibitors - The present invention relates to dihydroisoxazoles that are useful for treating cellular proliferative diseases, for treating disorders associated with KSP kinesin activity, and for inhibiting KSP kinesin. The invention also relates to compositions which comprise these compounds, and methods of using them to treat cancer in mammals. | 01-01-2009 |
20090118200 | Proline bis-amide orexin receptor antagonists - The present invention is directed to proline bis-amide compounds which are antagonists of orexin receptors, and which are useful in the treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which orexin receptors are involved. | 05-07-2009 |
20090124641 | Mitotic Kinesin Inhibitors - The present invention relates to fluorinated 2-aminomethylquinazolinone derivatives that are useful for treating cellular proliferative diseases, for treating disorders associated with KSP kinesin activity, and for inhibiting KSP kinesin. The invention also related to compositions which comprise these compounds, and methods of using them to treat cancer in mammals. | 05-14-2009 |
20090258852 | Inhibitors of Checkpoint Kinases - The instant invention provides for compounds which comprise benzoisoquinolinones and aza derivatives that inhibit CHK1 activity. The invention also provides for compositions comprising such inhibitory compounds and methods of inhibiting CHK1 activity by administering the compound to a patient in need of treatment of cancer. | 10-15-2009 |
20110224447 | Novel Lipid Nanoparticles and Novel Components for Delivery of Nucleic Acids - The instant invention provides for novel lipid nanoparticles and novel lipid nanoparticle components (specifically cationic lipids) that are useful for the delivery of nucleic acids, specifically siRNA, for therapeutic purposes. | 09-15-2011 |
20140275167 | HEPATITIS B ANTIVIRAL AGENTS - Provided herein are compounds useful for the treatment of HBV infection in man. | 09-18-2014 |
George D. Hartman, Radnor, PA US
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20130251673 | HEPATITIS B ANTIVIRAL AGENTS - The present invention includes a method of inhibiting, suppressing or preventing HBV infection in an individual in need thereof, comprising administering to the individual a therapeutically effective amount of at least one compound of the invention. | 09-26-2013 |
20140179665 | HEPATITIS B ANTIVIRAL AGENTS - The present invention includes a method of inhibiting, suppressing or preventing HBV infection in an individual in need thereof, comprising administering to the individual a therapeutically effective amount of at least one compound of the invention. | 06-26-2014 |
George D. Hartman, Doylestown, PA US
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20140178337 | HEPATITIS B ANTIVIRAL AGENTS - The present invention includes a method of inhibiting, suppressing or preventing HBV infection in an individual in need thereof, comprising administering to the individual a therapeutically effective amount of at least one compound of the invention. | 06-26-2014 |
Helen B. Hartman, Havertown, PA US
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20080299118 | FXR Agonists for the Treatment of Malignancies - Provided are certain methods of treating maligancies with farnesoid X receptor agonists. Also provided are certain methods of inducing RECK gene expression with farnesoid X receptor agonists and methods of reducing at least one feature of a cell with farnesoid X receptor agonists | 12-04-2008 |
Helen Bayes Hartman, Havertown, PA US
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20090137516 | COMPOSITIONS AND METHODS OF TREATING DYSLIPIDEMIA - The invention relates to the treatment of subjects for the purpose of reducing serum LDL, VLDL, triglycerides and fatty acids, by administering agents which reduce the activity of the bile acid pathway component SHP. Methods and pharmaceutical preparations comprising such agents are provided. | 05-28-2009 |
Joshua Hartman, Conshohocken, PA US
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20150120725 | METHOD AND SYSTEM FOR GENERATING A MASTER CLINICAL DATABASE AND USES THEREOF - A method and system for generating a master clinical database from disparate sources, including public databases, private databases, and data from users, correlating the received data, determining a degree of confidence in and requesting and seeking confirmation of any data matched from the correlated data. The invention may identify key time points and users from whom to seek and receive confirmation of correlated data. The invention may be utilized to create a cross-trial, cross-sponsor, clinical master database that maintains appropriate user, subject and data confidentiality and privacy and which may be utilized to facilitate study design collaboration. | 04-30-2015 |
Kevin T. Hartman, York, PA US
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20100200605 | Blow Molded Plastic Container Assembly With Improved Lid Sealing - A plastic container that is preferably formed using a blow molding and trimming process includes a container main body portion and a lid mounting portion. The lid mounting portion includes a sealing flange and a flexible transition portion connecting the sealing flange to the container main body portion. The flexible transition portion preferably has at least one notch defined therein so as to form a hinge permitting downward movement of the sealing flange when a lid is secured on to the container. In another embodiment, more than one notch is provided defining multiple hinges that provide a compound hinge effect in order to reduce stresses on the molded plastic material during use of the container. | 08-12-2010 |
Michael G. Hartman, Lansdale, PA US
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20090266460 | Hub bore mounted central tire inflation valve system - A system and apparatus for installing a central tire inflation (CTI) valve containing member into the hub bore opening of a wheel so as to be in communication with an air passageway hub port in the vehicle hub. Preferably, the CTI valve containing member includes a CTI valve sealed to a hub bore manifold with the hub bore manifold being mounted to the wheel disc and/or the vehicle hub. The hub bore manifold seals against the vehicle hub and the wheel hub bore surface (and/or the front face of the wheel disc). An air passageway in the manifold runs from the vehicle hub port to the CTI valve, and other air passageway(s) connect the CTI valve to the tire interior, such that air can travels from the vehicle hub to and from the tire cavity by way of the manifold and CTI valve. | 10-29-2009 |
20120138202 | Hub Bore Mounted Central Tire Inflation Valve System - A central tire inflation system. The system includes a central tire inflation valve and a hub bore manifold. The hub bore manifold is connected to and surrounds the central tire inflation valve. The hub bore manifold defines first and second air passageways which are in communication with the central tire inflation valve. The hub bore manifold is configured for removable connection to a hub of a vehicle and is also configured to fit within a central opening of a wheel of the vehicle. | 06-07-2012 |
Michael S. Hartman, Sinking Spring, PA US
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20090213580 | LAMP AND ILLUMINATED HARDSCAPE - A lamp and a hardscape structure illuminated by the lamp are disclosed. The lamp is formed from a plate to which a light fixture is attached. The plate may have a flange, a decorative face plate and side panels attached to direct light from the fixture along the hardscape on which the lamp is mounted. Mounting is effected by positioning the plate between discrete hardscape elements that are stacked one atop another. A portion of the plate projects out from the structure allowing the fixture to cast light on the structure surface. A light transmitting cover is also provided. | 08-27-2009 |
20120188751 | LAMP AND ILLUMINATED HARDSCAPE - A lamp and a hardscape structure illuminated by the lamp are disclosed. The lamp is formed from a plate to which a light fixture is attached. The plate may have a flange, a decorative face plate and side panels attached to direct light from the fixture along the hardscape on which the lamp is mounted. Mounting is effected by positioning the plate between discrete hardscape elements that are stacked one atop another. A portion of the plate projects out from the structure allowing the fixture to cast light on the structure surface. A light transmitting cover is also provided. | 07-26-2012 |
20120236547 | LIGHTING ASSEMBLY AND ILLUMINATED DECKING - A lighting assembly for illuminating a deck area having a longitudinally extending base plate having a front side and a back side, a lamp having at least one LED and a circuit board, and a heat sink connected to said circuit board. The lighting assembly and the electrical wire can be hidden from view, providing a more aesthetically pleasing appearance. Furthermore, the lighting system can be installed simultaneously with the deck itself, or afterwards. | 09-20-2012 |
20130308302 | LIGHT FIXTURE AND ILLUMINATED HARDSCAPE - A lamp adapted for mounting on a wall structure having a front face. The lamp includes a plate positionable within an opening in the front face of the wall. The plate has a top side and an underside and a front edge and a back edge. The back edge extends in a substantially semi-circular shape. A flange attached to the front edge of said plate is oriented at an angle relative to the plane of the plate. A light fixture is positioned adjacent the underside of the plate within a perimeter defined by the plate and a surface of the flange. A method of creating an illuminated hardscape is also disclosed. | 11-21-2013 |
20140233222 | LAMP AND ILLUMINATED HARDSCAPE - A lamp and a hardscape structure illuminated by the lamp are disclosed. The lamp is formed from a plate to which a light fixture is attached. The plate may have a flange, a decorative face plate and side panels attached to direct light from the fixture along the hardscape on which the lamp is mounted. Mounting is effected by positioning the plate between discrete hardscape elements that are stacked one atop another. A portion of the plate projects out from the structure allowing the fixture to cast light on the structure surface. A light transmitting cover is also provided. | 08-21-2014 |
Robert A. Hartman, Brigeville, PA US
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20140188499 | HUMAN ACTION MONITOR - Systems and corresponding methodologies that enable continuous, real-time or near real-time monitoring of joint activity of patients who are undergoing physical therapy is provided. A joint's motion patterns can be measured using a six degree of freedom combine accelerometer, magnometer and gyroscope sensors that are placed above and below (or in proximity of) the joint. The data is stored on a data logger that is carried by a patient, e.g., clipped to the patient's belt and can be uploaded onto a website when attached to a computer, e.g., via a USB cord. While portable sensors are available in the market for research or gaming purposes, one key feature of the device is to provide continuous monitoring of the injured joint and electronically relay this information to the therapist, for example, via the designated website. Thus, the therapist is always informed about the patient's joint and could recommend alterations to their treatment plan. | 07-03-2014 |
Thomas W. Hartman, Pittsburgh, PA US
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20140208916 | MANDOLINE SLICER - A food slicer includes a frame for supporting a landing and a runway movable relative to the landing. A cutting blade is secured on an upstream end of the landing. A downstream end of the runway is spaced from an edge of the cutting blade. A separate cutting knife is moveably connected to the frame. An adjustment mechanism connected to the frame adjusts an offset between the cutting blade and the runway. The adjustment mechanism includes spaced apart first and second guide tracks provided on respective first and second movable side members. The guide tracks are configured such that a first movement of the adjustment mechanism moves the downstream end of the runway relative to the cutting blade to adjust a cutting thickness and a second movement of the adjustment mechanism lowers the downstream end of the runway and raises the cutting knife to a working position. | 07-31-2014 |
Todd J. Hartman, Hummelstown, PA US
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20140217079 | SYSTEM FOR SNOW AND ICE REMOVAL - A system for removing frozen precipitation that has accumulated on an upper exterior surface of a road vehicle. In an embodiment, the system includes a hydrophobic and/or low friction sheet attached to an upper exterior surface of the road vehicle. The system may further include a heating array attached to the surface and a power source. | 08-07-2014 |