| Patent application number | Description | Published |
|---|
| 20090280138 | PEPTIDE - The present invention relates to peptide epitopes of 5T4 antigen and their use in immunotherapy. In particular, the present invention relates to any one of the peptide epitopes as described herein as well as their use in diagnosis and therapy of cancer. | 11-12-2009 |
| 20100124534 | IMMUNOTHERAPEUTIC METHOD - The present invention provides a method of monitoring the efficacy of an immunotherapy in a mammalian subject, wherein the subject has been administered an immunotherapy, wherein the immunotherapy comprises a viral vector containing a polynucleotide encoding an antigen, wherein the viral vector is capable of transducing cells in the mammalian subject to cause the cells to express the antigen; the method comprising:
| 05-20-2010 |
| 20120039943 | FACTORS - A method for determining a prognosis for benefit for a cancer patient receiving immunotherapy treatment involving (a) measuring a level of platelets and haemoglobin in a sample from the cancer patient, and (b) comparing the level of platelets in the sample to a reference level of platelets and comparing the level of haemoglobin in the sample to a reference level of haemoglobin, wherein a lower level of platelets and higher level of haemoglobin in the sample correlates with increased benefit to the patient. | 02-16-2012 |
| Patent application number | Description | Published |
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| 20090276767 | Computer System and a Method of Deploying an Application in a Computer System - A computer system has a runtime environment (e.g. Java) and a deployment unit (e.g. in a Spring framework layer) arranged to deploy the application into the runtime environment. The application comprises bundles (e.g. OSGi bundles) with manifest metadata having export statements defining exported packages. The deployment unit comprises a receiver unit to receive the bundles, an extractor unit to examine the metadata and extract the export statements, a converter unit to convert each of the export statements into a corresponding import statement, and a creator unit to add a synthetic bundle having the import statements inserted in its metadata. The deployment unit sets a thread context class loader to delegate class loading to a class loader of the synthetic bundle. Thus, at runtime, classes of the application are only loaded when they are explicitly exported packages as defined by the synthetic bundle. | 11-05-2009 |
| 20090276769 | Computer System and a Method of Deploying an Application in a Computer System - A computer system has a runtime environment (e.g. Java) and a deployment system (e.g. a Spring framework layer) arranged to deploy an application into the runtime environment. The application comprises bundles (e.g. OSGi bundles or JSR modules) each with manifest metadata defining dependencies for the respective bundle. A deployment management unit refers to one or more personality specific deployers to determine which of the bundles have a specific personality from a predetermined set of personality types. The personality specific deployers transform the respective personality-specific bundles by inserting one or more additional dependencies into the metadata of the bundle according to their personality type. The deployment management unit applies one or more operations to all of the plurality of bundles, including installing each of the bundles ready for deployment and deploys those bundles not having a specific personality type. The personality specific deployers deploy the personality-specific bundles according to their respective personality types. | 11-05-2009 |
| 20100138818 | Computer System and Method for Resolving Dependencies in a Computer System - A computer system and a method are disclosed for use in automatically deploying an application program to execute with one or more library resources. The computer system includes a deployment unit which deploys the application program into a runtime execution environment. When a predetermined trigger condition is detected, the deployment unit clones a first library resource to create a clone, transforms the application to depend upon the clone and resolves the dependencies of the application using the clone. In one embodiment, the trigger condition relates to a pinning situation, whereby a library upon which the application program depends cannot be wired to the application program to resolve the dependency. Here, the clone now satisfies that dependency. In another embodiment, the trigger condition is a mandatory cloning property that requires the library to be cloned. The mandatory cloning property may also be user-specified through a user interface. | 06-03-2010 |
| 20100138825 | Computer System and Method for Configuring an Application Program in a Computer System - A computer system which configures an application program to execute with one or more resources is disclosed. The computer system includes a configuration unit to configure the application program for deployment into a runtime execution environment. The application program is divided into a plurality of bundles and the configuration unit examines the bundles individually to determine a bundle environment for each bundle based on dependencies of that bundle on the one or more resources. The configuration unit selects one or more conventions, which provide templates of configuration for a relevant resource, according to the determined bundle environment, and the configuration unit automatically generates a system configuration from the selected conventions and adds the generated system configuration to the application program, whereby the dependencies of the application program upon the resources are configured based on at least the automatically generated system configuration. | 06-03-2010 |
| 20100186013 | Controlling Access to a Shared Resource in a Computer System - A computer system and method are provided that control access to shared resources using a plurality of locks (e.g. mutex locks or read-write locks). A locking unit grants the locks to a plurality of threads of execution of an application in response to lock access requests. A guardian unit monitors the lock access requests and records the locks that are granted to each of the threads. The guardian unit selectively blocks the lock access requests when, according to a predetermined locking protocol, a requested lock must not be acquired after any of the locks which have already been granted to the requesting thread. | 07-22-2010 |
