| Patent application number | Description | Published |
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| 20100132718 | Occlusion Stent - A device for occluding a target body lumen, comprises a wire structure defining a wire structure lumen extending therethrough and movable between a reduced diameter insertion configuration and an expanded diameter deployed configuration and a basket structure extending across the wire structure lumen and including therein a cell growth promoting agent to promote cell growth across the wire structure lumen to occlude the target body lumen. | 06-03-2010 |
| 20100269838 | MAGNETIC PARTICLES FOR DELIVERING THERAPEUTIC AGENT TO A TARGET LOCATION - A system for delivering therapeutic agent to a target location in a body in accordance with one embodiment is provided comprising a plurality of magnetic particles, each magnetic particle carrying a therapeutic agent, and a magnetic device for attracting the magnetic particles to a target location. The magnetic particles may be delivered by a catheter into a blood vessel upstream from the target location so that they travel toward the target location. A method for delivering therapeutic agent to a target location in a body in accordance with another embodiment comprises providing a plurality of magnetic particles, each magnetic particle carrying a therapeutic agent, placing a magnetic device in a position to attract the magnetic particles to a target location, and allowing the magnetic particles to infuse the target location by the attraction of the magnetic particles to the magnetic device. The therapeutic agent may comprises a therapeutic agent for preventing or treating reperfusion injury, and the step of providing the plurality of magnetic particles may comprise delivering the plurality of magnetic particles through a blood vessel. | 10-28-2010 |
| 20100331760 | BIODEGRADABLE IMPLANT FOR TREATING OR PREVENTING REPERFUSION INJURY - A biodegradable implant for iontophoretic therapeutic agent delivery is provided. The implant comprises a biodegradable battery and at least one biodegradable iontophoresis electrode assembly. The biodegradable battery comprises first and second biodegradable electrodes and a biodegradable polymer electrolyte layer between the first and second biodegradable electrodes. The biodegradable iontophoresis electrode assembly comprises a biodegradable iontophoresis electrode and a charged therapeutic agent. When the biodegradable battery is electrically connected to generate an electric current through the biodegradable iontophoresis electrode assembly, the charged therapeutic agent is delivered by iontophoresis to a target location. The charged therapeutic agent may be a scavenger for reactive oxygen species. The electrical connection of the biodegradable battery may be controlled remotely. | 12-30-2010 |
| 20100331775 | IMPLANTABLE SELF-POWERED BIODEGRADABLE MEDICAL DEVICE TO TREAT OR PREVENT REPERFUSION INJURY - In one embodiment, the present disclosure provides a biodegradable, self-powered medical device for preventing or reducing reperfusion injury, comprising a galvanic cell, the galvanic cell comprising: a first biodegradable electrode member; and a second biodegradable electrode member comprising a biodegradable conductive polymer and an electrode-releasable therapeutic agent, wherein the galvanic cell generates an electric force sufficient to cause the electrode-releasable therapeutic agent to be released from the biodegradable conductive polymer and elute to a target location. The device may further include a reservoir material containing a burst-release therapeutic agent. | 12-30-2010 |
| 20110137155 | DELIVERY DEVICE FOR LOCALIZED DELIVERY OF A THERAPEUTIC AGENT - Therapeutic agent delivery devices and methods for delivering a therapeutic agent to a target location as well as methods for determining the location of a lesion on a vessel wall are disclosed. Various embodiments disclose an expandable member comprising a drug delivery matrix for selectively delivering a therapeutic agent to a lesion on a vessel wall. The drug delivery matrix may comprise one or more sensors and an electroactive polymer for releasing the therapeutic agent. Other embodiments disclose an expandable member comprising a plurality of radially-expanding flexible walls forming a plurality of channels for selectively delivering therapeutic agent to a target area adjacent one or more of the channels. Detecting a lesion may comprise using a plurality of Hall effect sensors disposed on a distal end of a catheter. | 06-09-2011 |
| Patent application number | Description | Published |
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| 20090076591 | Stent Design Allowing Extended Release of Drug and/or Enhanced Adhesion of Polymer to OD Surface - The invention is directed to mechanisms and methods that reduce the delamination of a therapeutic agent from a stent. The mechanisms include holes (channels, wells, and other hole configurations), protrusions, sintered metal cores, clamps/staples, pins, and stainless steel shields. | 03-19-2009 |
| 20100056985 | ELECTROACTIVE POLYMER ACTIVATION SYSTEM FOR A MEDICAL DEVICE - An activation circuit for selectively providing an electrical current to one or more electroactive polymers (EAPs) in a medical device is disclosed. The activation circuit may include a sensor for sensing a measure related to a parameter of an elongated member and/or a balloon of the medical device. The electrical current may be provided to the one or more EAPs according to the sensed parameter of the elongated member and/or the balloon of the medical device. In some cases, the activation circuit may include a comparator for comparing the sensed measure to a threshold to determine when the electrical current is applied to the EAPs. The parameter may be a pressure, a fluid flow, a temperature, and/or other suitable parameter. | 03-04-2010 |
| 20100057174 | ELECTRICALLY CONDUCTIVE PATHWAYS IN MEDICAL DEVICES - Apparatuses, systems, and methods for electrically conductive pathways in medical devices. One embodiment of a medical device can include an elongate polymeric body having a proximal end and a distal end. Discrete particles of an electrically conductive material in the elongate polymeric body can form an electrically conductive pathway that extends at least partially between the proximal end and the distal end of the elongate polymeric body. | 03-04-2010 |
| 20110004297 | TRANSLUMENAL APPARATUS, SYSTEM, AND METHOD - Methods, apparatus, and systems for altering the configuration of a heart valve. Methods, apparatus, and systems include the use of a cord delivered into the heart by a delivery catheter that can be manipulated by a receiving catheter so as to improve the heart valve function. | 01-06-2011 |
