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Harold E.
Harold E. Asbridge, Rowlett, TX US
| Patent application number | Description | Published |
|---|---|---|
| 20080252522 | ARRAY ANTENNA AND A METHOD OF DETERMINING AN ANTENNA BEAM ATTRIBUTE - A method of determining one or more attribute of an antenna beam based on measuring phase and/or amplitude differences at different points in a feed network. By using lookup tables based on actual measurements of antenna beam attributes for phase and/or amplitude differences at different points in a feed network computation may be simplified. The method enables a relatively inexpensive control circuit to be employed while providing accurate measurement of antenna beam attributes. | 10-16-2008 |
Harold E. Ayliffe, Salt Lake City, WA US
| Patent application number | Description | Published |
|---|---|---|
| 20100288941 | FLUORESCENCE-BASED PIPETTE INSTRUMENT - An improved pipette tip ( | 11-18-2010 |
Harold E. Ayliffe, Woodinville, WA US
| Patent application number | Description | Published |
|---|---|---|
| 20090189088 | Fluorescence-activated cell detector - An apparatus for detecting particles of interest that are dispersed in a fluid mix, which typically includes other particles. The apparatus typically is associated with an interrogation platform arranged to operate in harmony with an opaque member having an orifice sized to promote single-file travel of the particles there-through. A currently preferred embodiment includes a light pipe configured to impinge stimulation-radiation substantially transverse to a direction of fluid flow through the opaque member. Particles of interest may be tagged using antibody-binding, fluorescing molecules. Stimulation radiation from the source causes the tagged particles to undergo a Stokes-shift emission of fluorescence. The resulting fluorescence is detected by the radiation detector and indicates passage of the particles of interest. One workable opaque member is advantageously included in a thin film assembly carried on a removable and disposable card that is adapted for reception in the interrogation platform. | 07-30-2009 |
| 20090272179 | Thin film particle sensor - A Coulter-style, microfluidic sensor formed by stacking a plurality of substantially non-electrically conductive layers, typically formed from thin polymer films. Certain layers carry patterned electrodes that are arranged to permit their connection to an electrical interrogation circuit. Electrodes may be disposed in a 3-dimensional array in the sensor. A fluid path through the sensor includes an orifice sized to promote single-file travel of particles. The orifice may be defined by a tunnel passing through at least one layer. Particles entrained in an electrolytic carrier fluid may be detected, or otherwise characterized, by interrogation circuitry connected to the sensor. Certain sensors may include portions of a fluid path disposed parallel to the layers. In certain preferred embodiments, the sensor is carried by a cartridge, which is adapted to couple with an interrogation platform. Desirably, such coupling places the sensor in-circuit with operable interrogation electronics, as well as with a fluid-flow control device. Structure included in a cartridge may provide fluid sample loading, routing, and storage capabilities. | 11-05-2009 |
| 20100199788 | INSTRUMENTED PIPETTE TIP - An improved pipette tip ( | 08-12-2010 |
| 20110030888 | METHOD FOR MANUFACTURING A MICROFLUIDIC SENSOR - A method to manufacture microfluidic sensors, typically including componentizing substrate layers One such method includes providing a plurality of layers of material configured to permit their stacking to form at least a first cap layer, a first channel layer, an interrogation layer, and a second channel layer During assembly, ribbon sections of substrate layers are sandwiched to cooperatively align elements through-the-thickness of the sandwich Individual sensors are then removed from the sandwich ribbon A componentizing step includes forming one or more elements for successive sensors spaced along the axial length of a ribbon Certain elements include electrically conductive patterned structures preferably printed onto a substrate using conductive ink and a printing process, sometimes placing material in operable position to conduct electricity through the thickness of at least one nbbon Other elements may include channels, tunnels, and vias that can be machined, stamped, or cut into a ribbon section. | 02-10-2011 |
| 20110162439 | REUSABLE THIN FILM PARTICLE SENSOR - A microfluidic sensor formed by stacking a plurality of substantially non-electrically conductive layers, typically formed from thin polymer films. Certain layers may carry patterned electrodes that are arranged to permit their connection to an electrical interrogation circuit. Electrodes may be disposed in a 3-dimensional array in the sensor. A fluid path through the sensor includes an orifice sized to promote single-file travel of particles. The orifice may be defined by a tunnel passing through at least one layer. Particles entrained in an electrolytic carrier fluid may be detected, or otherwise characterized, by interrogation circuitry connected to certain embodiments of the sensor. Sensors generally include portions of a fluid path disposed parallel to the layers. Sensors may operate under the Coulter principle, and/or Stokes' shift phenomena. In certain embodiments, the sensor may be carried by a cartridge, which is adapted to couple with an interrogation platform. In any case, coupling desirably places the sensor in-circuit with operable interrogation structure, as well as with a fluid-flow control device. Structure included in a cartridge may provide fluid sample loading, routing, and storage capabilities. | 07-07-2011 |
| 20110189650 | MICROFLUIDIC CELL SORTER WITH ELECTROPORATION - A biological particle manipulating device and method of its use. The device includes structure arranged to urge biological particles into substantially single file travel through an interrogation zone. Operable alignment structure nonexclusively include sheathed fluid flow, capillary tubes, an orifice, and fluid microchannels. One or more detector, selected from a plurality of operable such structures, may be employed to sense the presence of a biologic particle in the interrogation zone. Certain exemplary detectors may operate on the Coulter principle, or may detect a Stokes' shift, or side-scatter radiation. Discrimination structure is generally provided to categorize particles as being in one or another sub-population of a mix of biological particles that may be carried in a fluid sample, such as by cell type, size, or the like. Particle manipulating structure is disposed to impose a change on substantially all particles in any selected sub-population while leaving unchanged substantially the remaining sub-population(s). The device may be operated to essentially purify (in a living or viable sense) a sample including biological particles that are carried in a fluid diluent. The device may also be operated to electroporate cells on either a discriminating, or nondiscriminating, basis. | 08-04-2011 |
| 20110189714 | MICROFLUIDIC CELL SORTER AND METHOD - A biological particle sorting device and method of its use. The device includes structure arranged to urge biological particles into substantially single file travel through an interrogation zone. Operable alignment structure nonexclusively include sheathed fluid flow, capillary tubes, an orifice, and fluid microchannels. One or more detector, selected from a plurality of operable such structures, may be employed to sense the presence of a biologic particle in the interrogation zone. Certain exemplary detectors may operate on the Coulter principle, or may detect a Stokes' shift, or side-scatter radiation. Discrimination structure is generally provided to categorize particles as being in one or another sub-population of a mix of biological particles that may be carried in a fluid sample, such as by cell type, size, or the like. Killing structure, such as a laser, is disposed to neutralize all particles in any undesired sub-population while leaving undamaged the desired sub-population(s). The device may be operated to essentially purify (in a living or viable sense) a sample including biological particles that are carried in a fluid diluent. | 08-04-2011 |
Harold E. Ayliffe, Hailey, ID US
| Patent application number | Description | Published |
|---|---|---|
| 20120046883 | PIPETTE INSTRUMENT - A pipette instrument | 02-23-2012 |
Harold E. Bellis, Ii, Garland, TX US
| Patent application number | Description | Published |
|---|---|---|
| 20090015526 | COLOR CONTROL ALGORITHM FOR USE IN DISPLAY SYSTEMS - A color control algorithm compensates variations in the display system so as to maintain color consistency in the projected images on the screen by constructing a color mapping table of the display system to include effects due to the variations and during image display applications, generating inputs of the color mapping table to include the effects due to the variations in the display system. | 01-15-2009 |
| 20090134332 | Infrared Encoded Objects and Controls for Display Systems - A system for displaying images comprises a plurality of light sources, comprising at least one non-visible light source. The system further comprises a spatial light modulator operable to modulate non-visible light from the non-visible light source to encode one or more objects and for presentation on a display. Finally, the system comprises a detector operable to detect at least a portion of the non-visible light presented on the display. | 05-28-2009 |
Harold E. Childers, Ii, Houston, TX US
| Patent application number | Description | Published |
|---|---|---|
| 20090139935 | Ballast Tank Circulation Management System - A method for managing ballast tank circulation system comprising a means for adding one or more halogens in controlled amounts to the water within the ballast tank. Test streams of water from the ballast tank can be analyzed to determine the level of halogens in the test stream to provide a halogen content signal. A controller receives the signal and compares the signal to a set point indicative of the level of halogen desired within the ballast tank to maintain, increase, or decrease the amount of chemical added to the water within the ballast tank in controlled amounts. | 06-04-2009 |
Harold E. Garey, Methuen, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100104880 | BIOCOMPATIBLE POLYMERS POLYMER, TIE-COATS-, METHODS OF MAKING AND USING THE SAME, AND PRODUCTS INCORPORATING THE POLYMERS - Biodurable, biocompatible polymers for coating applications and tie-coat polymers especially useful in tie-coat applications as an intermediate layer between two other layers or coatings or between a surface and a coating applied to that surface are disclosed, together with methods for preparing such biocompatible polymers and tie-coat polymers, methods for using such biocompatible polymers and tie-coat polymers, and products that use or incorporate such biocompatible polymers and tie-coat polymers. The biocompatible polymers generally comprise polyurethane polymers having polycarbonate backbones, and the tie-coat polymers useful with these biocompatible polymers generally comprise polyurea or polyurethane-polyurea polymers. | 04-29-2010 |
Harold E. Gottschalk, Jr., El Cajon, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20110260832 | SECURE VOICE BIOMETRIC ENROLLMENT AND VOICE ALERT DELIVERY SYSTEM - In one embodiment, a method includes enrolling a potential enrollee for an identity-monitoring service. The enrolling includes acquiring personally-identifying information (PII) and capturing a voiceprint. Following successful completion of the enrolling, the potential enrollee is an enrollee. The method further includes, responsive to an identified suspicious event related to the PII, creating an identity alert, establishing voice communication with an individual purporting to be the enrollee, and performing voice-biometric verification of the individual. The voice-biometric verification includes comparing one or more spoken utterances with the voiceprint. Following successful completion of the voice-biometric verification, the individual is a verified enrollee. In addition, the method includes authorizing delivery of the identity alert to the verified enrollee. | 10-27-2011 |
Harold E. Hudson, Ii, Conover, NC US
| Patent application number | Description | Published |
|---|---|---|
| 20110211793 | OPTICAL FIBER ASSEMBLIES - Fiber optic assemblies include subunit cables wrapped in binders. The assemblies have small cross sections and low bend radii while maintaining acceptable attenuation losses. SZ stranding of the subunit cables allows ease of access to the individual cables during installation. | 09-01-2011 |
Harold E. Miller, Upland, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20100163049 | RESPIRATORY MASK - A respiratory mask includes a mask frame, a cushion and a retaining element. The retaining element is embedded within the cushion and is configured to secure the cushion to the mask frame. Forehead pads can be positioned in the mask frame and be adjustable independent of one another and with respect to the mask frame. | 07-01-2010 |
Harold E. Pahlck, Waldwick, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20100028069 | Shaper - A shaper for defining a tip portion of a cosmetic unit that has become worn includes a a shaping surface for smoothing a surface of the tip portion and a slot in the shaping surface. The shaping surface is user-selectably placed in contact with the tip portion. An edge disposed at the slot and is engageable for removing material of the tip portion when the shaping surface is in contact with tip portion. The removed material is passed through the slot. | 02-04-2010 |
Harold E. Pahlick, Waldwick, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20100221294 | Use of Non-Straight Fiber Dispersed in a Composition and Compositions Thereof - Compositions and methods for enhancing, lengthening, volumizing, or concealment of keratinous surfaces or tissue. The compositions comprise non-straight fibers useful for formulating cosmetics, personal care products, and pharmaceutical compositions which are comfortable, durable, and overcome smudging, smearing, flaking, and detachment from keratinous surfaces, thereby resulting in an aesthetically pleasing appearance. | 09-02-2010 |
Harold E. Quicke, Auburn, AL US
| Patent application number | Description | Published |
|---|---|---|
| 20090176648 | Herbicidal Mixture, Comprising an Imidazolinone Herbicide and an Adjuvant - A herbicidal mixture, comprising | 07-09-2009 |
Harold E. Selick, Belmont, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20100104549 | GLUFOSFAMIDE COMBINATION THERAPY - The co-administration of glufosfamide and a glucose lowering drug other than insulin is efficacious in cancer treatment. | 04-29-2010 |
Harold E. Stockton, Jr., Round Rock, TX US
| Patent application number | Description | Published |
|---|---|---|
| 20100242534 | HYBRID CASCADE VAPOR COMPRESSION REGRIGERATION SYSTEM - An exemplary system includes a first heat exchanger immediately after the compressor that provides direct, conduction-based cooling with condensate recovered from the evaporator. A second heat exchanger cools the forced air that passes over the condenser by evaporating recovered condensate, rainwater, and/or city water into the air as it passes through a breathable water-retaining medium. Finally, a third heat exchanger is described that utilizes recovered condensate, rainwater, and/or city water within an insulated enclosure to obtain additional cooling before the condensed refrigerant enters the expansion valve. Various alternative embodiments are described that include variations of each of these heat exchangers. Additionally, several alternative placements of the heat exchangers are disclosed. | 09-30-2010 |
Harold E. Varmus, New York, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20100210649 | PYRIDAZINONES AND FURAN-CONTAINING COMPOUNDS - The present invention is directed to pyridazinone compounds of formula (I) and furan compounds of formula (II), pharmaceutical compositions of compounds of formula (I) and (II), kits containing these compounds, methods of syntheses, and a method of treatment of a proliferative disease in a subject by administration of a therapeutically effective amount of a compound of formulae (I) or (II). Both classes of compounds were identified through screening of a collection of small molecule libraries. | 08-19-2010 |
Harold E. Vincent, Jr., Raleigh, NC US
| Patent application number | Description | Published |
|---|---|---|
| 20100235688 | Reporting And Processing Computer Operation Failure Alerts - Reporting and processing computer operation failure alerts, including deploying on a computer in a computing environment a plurality of alert reporting agents, the computing environment including a plurality of computers including a system management server that monitors the operating conditions of the other computers in the computing environment, the computer also including an alert generator configured to accept registrations of alert reporting agents, to generate alerts of present or pending failure, and to provide the generated alerts to registered alert reporting agents; registering the alert reporting agents with the alert generator; designating a primary alert reporting agent among registered alert reporting agents that communicate alerts to a same system management server; communicating a computer operation failure alert to all registered agents; and communicating, by the primary alert reporting agent only, the alert to the system management server. | 09-16-2010 |