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Harold C. Smith

Harold C. Smith, Rochester, NY US

Patent application numberDescriptionPublished
20090099105Content dependent inhibitors of cytidine deaminases and uses thereof - This invention relates to cytidine deaminase inhibitors (Cytidine deaminase inhibitors) of cytidine deaminases and uses thereof.04-16-2009
20100016253METHODS AND COMPOSITIONS RELATED TO HEIGHTENED APOBEC-1 RELATED PROTEIN (ARP) EXPRESSION - Disclosed are methods and compositions related to determining the status and mechanisms underlying long-term nonprogression of viral infections.01-21-2010
20100029570PEPTIDE AND TREATMENT FOR HIV-1 INFECTION - A compound of the formula X02-04-2010
20100100976METHODS AND COMPOSITIONS RELATED TO APOBEC-1 EXPRESSION - Disclosed are methods and compositions related to APOBEC-1.04-22-2010
20100160174PROTEIN TRANSDUCING DOMAIN/DEAMINASE CHIMERIC PROTEINS, RELATED COMPOUNDS, AND USES THEREOF - Disclosed are compositions for chimeric proteins comprising a protein transduction domain and a deaminase domain, mimetics or analog thereof, and uses of same.06-24-2010
20100197768METHODS AND COMPOSITIONS RELATED TO THE STRUCTURE AND FUNCTION OF APOBEC3G - Disclosed are methods and compositions related to the structure and function of APOBEC3G.08-05-2010
20100297219Methods and Compositions for Modifying Apolipoprotein B mRNA Editing - Products and methods for modifying apolipoprotein B mRNA editing in vivo, reducing serum LDL levels, and treating or preventing an atherogenic disease or disorder are disclosed. Such methods involve the use of a protein including APOBEC-1 or fragments thereof which can edit mRNA encoding apolipoprotein B. The protein including APOBEC-1 can be taken up by cells in the form of a delivery vehicle, such as a liposome or niosome, or directly as a chimeric protein which includes a first polypeptide that includes a protein transduction domain and a second polypeptide that includes APOBEC-1 or a fragment thereof which can edit mRNA encoding apolipoprotein B.11-25-2010
20110152107Drug Screening Via Nanpore Silicon Filters - The invention provides a porous nanoscale membrane. In one embodiment, the membrane can be used as a filtration device to screen agents that disrupt or prevent molecular interactions. In one embodiment, the membrane allows for screening agents that disrupt or prevent molecular interactions using a small sample volume with efficient high-throughput screening applications.06-23-2011

Patent applications by Harold C. Smith, Rochester, NY US

Harold C. Smith, South Rochester, NY US

Patent application numberDescriptionPublished
20090075925Methods and Compositions Related to APOBEC-1 Expression - Disclosed are methods and compositions related to ACF and to APOBEC-1.03-19-2009