Patent application number | Description | Published |
20090111870 | Angelicae Sinensis Extracts Useful for Treatment of Cancers - An acetone extract, chloroform extract or hexane extract of | 04-30-2009 |
20110165201 | ANTICANCER FORMULATION - This invention relates to a pharmaceutical formulation containing z-butylidenephthalide and a polymer, e.g., a polyanhydride. Also disclosed is use of this formulation to treat tumor. | 07-07-2011 |
20110274664 | HEPATIC PROGENITOR CELLS AND USES THEREOF - Disclosed are cells, compositions, and methods for treating liver diseases. | 11-10-2011 |
20130158108 | USES OF N-BUTYLIDENEPHTHALIDE IN TREATING A LIVER INJURY AND IMPROVING LIVER FUNCTION - Provided is a method for treating a liver injury such as fibrosis, cirrhosis and hepatitis as well as a method for restoring liver function in a subject, which includes administrating to the subject a therapeutically effective amount of n-butylidenephthalide having the formula (I) as an active ingredient, or a pharmaceutically acceptable salt of ester thereof: | 06-20-2013 |
20150216836 | ANTICANCER FORMULATION - This invention relates to a pharmaceutical formulation containing z-butylidenephthalide and a polymer, e.g., a polyanhydride. Also disclosed is use of this formulation to treat tumor. | 08-06-2015 |
Patent application number | Description | Published |
20110178171 | COMPOUNDS FOR CANCER THERAPY - A method of inhibiting the cellular proliferation of at least one selected from the group consisting of androgen dependent prostate cancer cells, androgen independent prostate cancer cells, oral cancer cells, liver cancer cells (hepatoma), and gastric cancer cells in a subject is provided, wherein the method comprises administrating to the subject an effective amount of an active component selected from the group consisting of Z form isochaihulactone (Z-K8) of the following formula (I), E form isochaihulactone (E-K8) of the following formula (II), a pharmaceutically acceptable salt of Z-K8 or E-K8, a pharmaceutically acceptable ester of Z-K8 or E-K8, and combinations thereof: | 07-21-2011 |
20120178803 | METHOD FOR TREATING BRAIN CANCER OR REDUCING TEMOZOLOMIDE-RESISTANCE OF BRAIN CANCER CELLS - Provided is a method for treating brain cancer or reducing temozolomide-resistance of brain cancer cells in a subject, comprising administrating to the subject an effective amount of an active ingredient selected from the group consisting of (Z)-butylidenephthalide of formula (I), a pharmaceutically acceptable salt of (Z)-butylidenephthalide, a pharmaceutically acceptable ester of (Z)-butylidenephthalide, and combinations thereof: | 07-12-2012 |
20130287717 | METHOD FOR IMPROVING SKIN APPEARANCE AND REDUCING HAIR LOSS - A method for improving skin appearance and/or reducing hair loss in a subject is provided. The method comprises administrating to the subject an effective amount of peripheral monocytes, wherein the peripheral monocytes are induced by granulocyte colony stimulating factor (GCSF) or a combination of GCSF and an interleukin relative to GCSF. | 10-31-2013 |
20140045765 | METHOD FOR INHIBITING AUTOPHAGY OF MOTOR NEURONS - A method for inhibiting the autophagy of motor neurons in a subject is provided. The method comprises administrating to the subject an effective amount of an active ingredient selected from the group consisting of a compound of formula (I), a pharmaceutically acceptable salt of the compound, a pharmaceutically acceptable ester of the compound and combinations thereof: | 02-13-2014 |
20140212970 | METHOD AND KIT FOR CULTURING STEM CELLS - A method is provided, including adding a phthalide to a stem cell medium to provide a phthalide-containing medium, and then culturing a stem cell using the phthalide-containing medium. The use of a phthalide in a medium for culturing stem cells optionally maintains the pluripotency of stem cells. The phthalide also enhances the generation efficiency of induced pluripotent stem cells to decrease the culture cost. | 07-31-2014 |
20150056702 | METHOD AND KIT FOR CULTURING STEM CELLS - A method is provided, including adding a phthalide to a stem cell medium to provide a phthalide-containing medium, and then culturing a stem cell using the phthalide-containing medium. The use of a phthalide in a medium for culturing stem cells optionally maintains the pluripotency of stem cells. The phthalide also enhances the generation efficiency of induced pluripotent stem cells to decrease the culture cost. | 02-26-2015 |
20150352213 | METHOD FOR TREATING PANCREATIC CANCER - A method for treating pancreatic cancer is provided. The method comprises administering to a subject in need thereof a therapeutically effective amount of a pharmaceutical formulation, wherein the pharmaceutical formulation comprises (Z)-butylidenephthalide and is substantially free of (E)-butylidenephthalide. | 12-10-2015 |
Patent application number | Description | Published |
20130231555 | IMAGE GUIDED SURGERY APPARATUS AND SYSTEM - An image guided surgery apparatus and system are provided. The image guided surgery system includes an image capturing system, an image scanner, a navigator, a surgical catheter and a surgical probe. The image capturing system has an elongated and flexible working tube for capturing a surface image, a structure image or a dynamic structure image of a tissue during the surgical catheter moving forward to the surgical part, thus determining the type and the structure of the tissue in the front-end of the surgical catheter. Therefore, whether a moving path of the surgical catheter is to at the correct position can be confirmed for reaching a correct surgical site. The surgical catheter assists the surgical probe directly reaching the optimal surgical site for performing a precise positioning surgery. | 09-05-2013 |
20140168654 | FIBER-TYPE IMAGE CAPTURING METHOD AND APPARATUS THEREOF - A fiber-type image capturing apparatus includes a fiber optic, an optical rotating module, an outer tube, an air inlet hole, and an air outlet hole. The optical rotating module is connected to one end of the fiber optic and has a light forward exit and a light lateral exit. The optical rotating module further includes a stator, a rotor, and a light path selector. The stator is fixed correspondingly to the fiber optic. The rotor has a fan blade which is pivotally connected to the stator. The light path selector is installed at the rotor and has a forward scanning path and a lateral scanning path. The outer tube fixes the fiber optic and the optical rotating module. The air inlet hole is disposed at the outer tube and feeds the fan blade with air. The air outlet hole is disposed at the outer tube and vents the air. | 06-19-2014 |
20140271568 | METHOD AND KIT FOR PROVIDING AN INCREASED EXPRESSION OF TELOMERASE, BRAIN-DERIVED NEUROTROPHIC FACTOR, STROMAL CELL-DERIVED FACTOR-1, CXC CHEMOKINE RECEPTOR 4, AND/OR IMMUNE REGULATORY FACTOR OF STEM CELL - A method for providing an increased expression of at least one of telomerase, brain-derived neurotrophic factor (BDNF), stromal cell-derived factor-1 (SDF1), CXC chemokine receptor 4 (CXCR4), and an immune regulatory factor of a stem cell in a subject is provided. The method comprises simultaneously or separately administering to the subject an effective amount of (a) a phthalide and (b) a stem cell. | 09-18-2014 |
20140296871 | SURGICAL GUIDING AND POSITION SYSTEM - The present invention discloses a surgical guiding and positioning system, comprising: a global information device, a local information device, and a computing device. The global information device is capable of collecting an overall information of a surgical site before a surgical procedure begins. The local information device can comprise a surgical device including at least one sensor and provide a real-time information of a section of the surgical site. The computing device is capable of calculating a position data of the surgical device in the surgical site by comparing the overall information and the real-time information. Therefore, the present invention is capable of providing the real-time guidance and monitoring during a surgical procedure so that the surgeon can acquire precise real-time information of the surgical site and perform the surgery efficiently. | 10-02-2014 |
20150306233 | STABLE PHARMACEUTICAL COMPOSITION - A pharmaceutical composition comprising:
| 10-29-2015 |
20160000751 | METHOD FOR TREATING AND/OR DELAYING THE DEGENERATION OF PURKINJE CELLS - A method for treating and/or delaying the degeneration of Purkinje cells in a subject is provided. The method comprises administering to a subject in need thereof a therapeutically effective amount of a medicament, wherein the medicament comprises a phthalide selected from the group consisting of n-butylidenephthalide (BP), a metabolic precursor of BP, a pharmaceutically acceptable salt of a metabolic precursor of BP, a pharmaceutically acceptable ester of a metabolic precursor of BP, and combinations thereof. | 01-07-2016 |