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Hao Li

Hao Li, Brookline, MA US

Patent application numberDescriptionPublished
20090253694Fused hetrocyclic compounds - This invention provides fused heterocyclic compounds, pharmaceutical compositions of the compounds, and methods of using the compounds for the treatment of, inter alia, IL-12 related disease and disorders.10-08-2009
20110059893COMPOUNDS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS - The invention relates to compounds of structural formula (I):03-10-2011
20110195094TRIAZOLE COMPOUNDS THAT MODULATE HSP90 ACTIVITY - The present invention relates to substituted triazole compounds and compositions comprising substituted triazole compounds. The invention further relates to methods of inhibiting the activity of Hsp90 in a subject in need thereof and methods for preventing or treating hyperproliferative disorders, such as cancer, in a subject in need thereof comprising administering to the subject a substituted triazole compound of the invention, or a composition comprising such a compound.08-11-2011
20110319447TRIAZOLE COMPOUNDS THAT MODULATE HSP90 ACTIVITY - The present invention relates to substituted triazole compounds and compositions comprising substituted triazole compounds. The invention further relates to methods of inhibiting the activity of Hsp90 in a subject in need thereof and methods for preventing or treating hyperproliferative disorders, such as cancer, in a subject in need thereof comprising administering to the subject a substituted triazole compound of the invention, or a composition comprising such a compound.12-29-2011

Patent applications by Hao Li, Brookline, MA US

Hao Li, Chandler, AZ US

Patent application numberDescriptionPublished
20090058257ACTIVELY CONTROLLED DISTRIBUTED BACKLIGHT FOR A LIQUID CRYSTAL DISPLAY - A liquid crystal display includes a field emission backlight (03-05-2009
20090102350FIELD EMITTER SPACER CHARGE DETRAPPING THROUGH PHOTON EXCITATION - A method and apparatus for neutralizing the charge on a spacer (04-23-2009
20090191334FORMING AN ELECTROWETTING MODULE HAVING A HYDROPHILIC GRID - A method of forming a matrix of electrowetting pixels includes forming a patterned layer of electrodes (07-30-2009
20090237374TRANSPARENT PRESSURE SENSOR AND METHOD FOR USING - A material (09-24-2009
20090297703INDUCED PHASE COMPOSITE TRANSPARENT HARD COATING - A method of forming a protective layer on a substrate (12-03-2009
20110050394SYSTEMS AND METHODS FOR PRESSURE-BASED AUTHENTICATION OF AN INPUT ON A TOUCH SCREEN - Systems and methods are provided for authenticating an input on a touch screen. A method comprises obtaining one or more pressure metrics for an input by a user on a touch screen that is being proffered as that of a known user. Each pressure metric corresponds to a pressure applied to the touch screen by the user at a respective impression location of the input. The method further comprises authenticating the user as the known user based at least in part on the one or more pressure metrics.03-03-2011
20110050588METHODS AND APPARATUS FOR PRESSURE-BASED MANIPULATION OF CONTENT ON A TOUCH SCREEN - Methods and apparatus are provided for manipulating content displayed on a touch screen utilizing a transparent pressure-sensing touch panel. A method comprises displaying content on the touch screen and obtaining one or more pressure metrics for an input gesture on the transparent pressure-sensing touch panel. Each pressure metric corresponds to pressure (or force) applied to the transparent pressure-sensing touch panel by a respective impression of the input gesture. The method further comprises adjusting the displayed content on the touch screen in response to the input gesture, wherein the displayed content is adjusted based on to the one or more pressure metrics for the input gesture.03-03-2011
20110227836TRANSPARENT FORCE SENSOR AND METHOD OF FABRICATION - A transparent force sensor for use in touch panel displays (touch screens) and method for fabricating the same are disclosed. The transparent force sensor is capable of detecting touch by measuring local pressure applied by a touch input to a display area of the touch screen.09-22-2011
20110273394METHODS AND APPARATUS FOR A TRANSPARENT AND FLEXIBLE FORCE-SENSITIVE TOUCH PANEL - Methods and apparatus are provided for a transparent and flexible pressure-sensing touch panel. The touch panel includes a flexible and substantially transparent composite layer (e.g., a plurality of conductive particles within a polymeric matrix) such that the resistivity of the composite layer is a function of applied force, and such that the touch panel may be manipulated to conform to a non-planar surface, such as a non-planar display screen.11-10-2011
20120026124TOUCH SCREEN RENDERING SYSTEM AND METHOD OF OPERATION THEREOF - A touch-screen display apparatus, the apparatus may include first and second sheets having opposed major surfaces and a size and shape defined by a periphery. The periphery may be defined by opposed ends and opposed edges. The first and second sheets may each have a conductive pattern including a pair of opposed busbars and a plurality of traces electrically coupled to, and extending between, corresponding pairs of opposed busbars. The transparent force sensing (TFS) sheet may have opposed major surfaces and a variable resistance which is related to a force exerted upon one or more of its major surfaces. The TFS sheet may be situated between the first and second sheets. The apparatus may also include one or more separation portions situated between the TFS sheet and the first or second sheet to bias the TFS sheet apart from the first or second sheet.02-02-2012

Patent applications by Hao Li, Chandler, AZ US

Hao Li, Munich DE

Patent application numberDescriptionPublished
20110032045OSCILLATOR CIRCUIT - The invention relates to an oscillator circuit comprising: a VCO core having an output terminal for providing an oscillatory output signal thereat and having a supply terminal for receiving a supply voltage from a voltage supply, a subsequent circuit coupled to the VCO core's output terminal and having a supply terminal for receiving a supply voltage from the voltage supply. According to the invention, a decoupling member is arranged between the VCO core's supply terminal and the subsequent circuit's supply terminal for preventing high-frequency signals generated by the subsequent circuit at its supply terminal from entering the VCO core. The decoupling member may comprise a transmission line the length of which is one quarter wavelength associated with a second-harmonic oscillation.02-10-2011
20110043401VOLTAGE-CONTROLLED OSCILLATOR AND RADAR SYSTEM - A voltage-controlled oscillator circuit comprises an output terminal for providing an oscillatory output signal thereat, a first inductor, a varactor, and a negative-resistance element. The varactor's capacitance is a function of a tuning potential applied at a first terminal of the varactor. A bias branch is present for coupling a second terminal of the varactor to a bias potential. The bias branch comprises a second inductor or a transmission line. The bias branch may comprise a transmission line the length of which is one quarter wavelength associated with the resonance frequency of the voltage-controlled oscillator circuit. A radar system including a VCO circuit is further disclosed.02-24-2011
20110128080VOLTAGE CONTROLLED OSCILLATOR (VCO) CIRCUIT WITH INTEGRATED COMPENSATION OF THERMALLY CAUSED FREQUENCY DRIFT - A voltage controlled oscillator circuit comprises a VCO resonator circuit having a first plurality of varactors for varying a frequency of the VCO resonator circuit the VCO resonator circuit being symmetrical with respect to VCO circuit ground and providing a signal having a frequency, the frequency depending on a tuning voltage applied to the first plurality of varactors, and a second plurality of varactors for compensating a drift of the frequency depending on a compensation voltage, a temperature sensor circuit sensing an ambient temperature of the VCO resonator circuit and providing a temperature dependent signal, and a temperature compensation circuit providing the compensation voltage depending on the temperature dependent signal. Furthermore, a phase locked loop (PLL) circuit, an automotive radar device and a method for compensating a frequency drift of a VCO resonator circuit are presented.06-02-2011

Hao Li, Shanghai CN

Patent application numberDescriptionPublished
20090171290INFUSION DEVICE FOR INFUSING MULTIPLE MEDICAMENTS AT DIFFERENT SPEEDS AND METHOD - An infusion device comprises a pump having first and second chambers that are sealed by a penetrable membrane; an injection catheter comprises a first passageway which is connected to the first chamber; and an expandable elastic pouch which is mounted to the injection catheter and is connected to the second chamber through inlet holes defined in a wall of the second passageway. The expandable elastic pouch further connects an outlet port of the injection catheter through some outlet holes which are also defined in the wall. Medicaments are filled into the chambers and can either be directly injected through to the first passageway, or transmitted to the elastic pouch. The elastic pouch is expanded, and accordingly, a pressure is induced on the medicament to effectively continuous deliver the medicament for a given period of time.07-02-2009
20100138729Pseudorandom binary sequence checker with control circuitry for end-of-test check - Control circuitry is coupled between an error event output and a data input of a pseudorandom binary sequence (PRBS) checker. The control circuitry is configured to switch between a first operating state in which a received PRBS signal is applied to the data input of the PRBS checker and a second operating state in which an error signal is applied to the data input of the PRBS checker, responsive to detection of a designated condition of the PRBS checker. In an illustrative embodiment, the designated condition is an end-of-test condition indicating that the PRBS checker has completed a test involving the received PRBS signal.06-03-2010
20110028900INFUSION DEVICE FOR INFUSING MULTIPLE MEDICAMENTS AT DIFFERENT SPEEDS - An infusion device includes a pump forming front and rear chambers for receiving medicaments therein. The medicaments supplied from the two chambers are respectively transmitted into an elastic reservoir forming first and second lumens through first and second passageways. Then, the medicaments are infused into a person through a catheter which defines one passageway toward the human body. The first passageway is in fluid communication with the front chamber and second lumen. The second passageway is in fluid communication with the rear chamber, the first lumen, and the second lumen. By making the diameter of a second hole which connects the first lumen and second lumen smaller than a first hole which connects the first passageway and the first lumen, the medicament from the second chamber can be infused into patient with a low concentration.02-03-2011

Patent applications by Hao Li, Shanghai CN

Hao Li, Etobicoke CA

Patent application numberDescriptionPublished
20100331227HYDROGEN PEROXIDE BASED CLEANING, SANITIZING, DEODORIZING AND SCALE INHIBITING SOLUTION - An environmentally friendly hydrogen peroxide cleaning and sanitizing solution is disclosed that may be used for cleaning, deodorizing, sanitizing and scale inhibiting in toilets and urinals in washroom and toilet areas. The solution also has the added benefit of eliminating odours and reducing corrosion in the washroom plumbing. The present cleaning and sanitizing solution consists of distilled water, hydrogen peroxide, a surfactant, a hydrogen peroxide stabilizer, a chelating agent, and corrosion inhibitors. The pH of the cleaning and sanitizing solution is greater than 6.0, and typically about 6.0 to about 8.0. The present cleaning, sanitizing, deodorizing and scale inhibiting solution is distributed to the washroom fixtures by means of refillable pump systems commonly known in the art.12-30-2010

Hao Li, Columbia, MO US

Patent application numberDescriptionPublished
20090283424SENSOR ELECTRODE AND METHOD FOR THE ELECTROCHEMICAL DETECTION OF NUCLEOTIDES - A sensor electrode for the detection of nucleotides in a biological sample is described. The sensitivity of the electrode is enhanced by the nanostructured sensor architecture that increases the available surface area of the electrode. The electrode detects nucleotides using standard electrochemical methods.11-19-2009
20100273129Atmospheric Non-Thermal Gas Plasma Method for Dental Surface Treatment - The provision of dental restorations can be improved by generating a cold atmospheric plasma inside the mouth of the patient and then applying that cold atmospheric plasma onto a dental restoration site. The dental restoration site can be composed of either or both of dentin and enamel. Further, the provision of dental restorations can also be improved by introducing a dental adhesive onto a dental restoration site and treating it with a cold atmospheric plasma.10-28-2010

Hao Li, Acton, MA US

Patent application numberDescriptionPublished
20100173413PYRIDINE COMPOUNDS - This invention features compounds of formula (I):07-08-2010

Hao Li, Cambridge, CA US

Patent application numberDescriptionPublished
20100104584GENES INVOLVED IN MITOCHONDRIAL BIOGENESIS - The invention discloses suitable gene and polypeptide targets for the development of new therapeutics to treat, prevent or ameliorate conditions associated with mitochondrial dysfunction. The invention also relates to methods to treat, prevent or ameliorate said conditions and pharmaceutical compositions therefor, as well as to a method to identify compounds with therapeutic usefulness to treat conditions associated with mitochondrial dysfunction.04-29-2010

Hao Li, Shenzhen City CN

Patent application numberDescriptionPublished
20090154177HINGE FOR A LAMP - A lamp hinge includes a first connector and a second connector pivotally connecting with the first connector. The first connector is formed on an upper end of a lamp pole and defines a circular chamber therein. The second connector is for connecting with a lamp head. Two arced engaging portions are formed on the second connector and are pivotally received in the chamber. The arced engaging portions are distributed in a same annulus and define a first arced gap and a second arced gap therebetween, adapted for providing passage of electric wires of the lamp. The first arced gap is communicated with a central hole of a mounting portion of the second connector. The second arced gap is communicated with a recessed portion of the lamp pole. The second arced gap is longer than five twelfths of a perimeter of the annulus where the arced engaging portions are distributed.06-18-2009
20090161375HINGE FOR A LAMP - A lamp hinge includes a first connector and a second connector pivotally connecting with the first connector. The first connector defines a circular groove therein. The second connector has a pivotal portion pivotally engaging the first connector, and a mounting portion connecting with a lamp head of the lamp. The pivotal portion defines a curved groove therein. The mounting portion defines a central hole therein. A plurality of ball bearings are movably sandwiched between the pivotal portion and the first connector and received in the circular groove and the curved groove. The ball bearings separate the first connector from the second connector a space. Two neighboring ball bearings define a gap therebetween, for providing passage of the electric wires of the lamp therethrough. The gap communicates with the central hole of the mounting portion of the second connector.06-25-2009
20090262542LED LAMP HAVING AN IMPROVED WATERPROOFING STRUCTURE - An LED lamp includes a heat sink, and a plurality of LED modules attached to the heat sink. The heat sink includes a base and a plurality of fins extending from the base. The LED modules each include a substrate plate thermally attached to the base of the heat sink and a plurality of LEDs mounted on the substrate plat. A housing includes a frame surrounding the base of the heat sink, and cooperates with the heat sink to define a first cavity between the frame and the base of the heat sink. A first waterproof gasket is received in the first cavity and surrounds the base of the heat sink. A hood covers over the LEDs of the LED modules and contacts the frame of the housing. A second cavity is defined among the hood, the frame of the housing and the body. A second waterproof gasket is received in the second cavity.10-22-2009

Hao Li, San Diego, CA US

Patent application numberDescriptionPublished
20090124540Anti-adhesion composites and methods of use thereof - Described herein are composites that inhibit or reduce adhesion between two or more tissues. Also described herein are methods of using the composites.05-14-2009

Hao Li, Poing DE

Patent application numberDescriptionPublished
20110285575INTEGRATED CIRCUIT COMPRISING FREQUENCY GENERATION CIRCUITRY FOR CONTROLLING A FREQUENCY SOURCE - An integrated circuit comprises frequency generation circuitry for controlling a frequency source for an automotive radar system. The frequency generation circuitry comprises a Phase Locked Loop (PLL) arranged to generate a control signal for controlling the frequency source, a fractional-N divider located within a feedback loop of the PLL, and frequency pattern control logic operably coupled to the fractional-N divider and arranged to control the fractional-N divider, by way of a frequency control signal, such that the PLL generates a Frequency Modulated Continuous Wave (FMCW) control signal.11-24-2011

Hao Li, Decatur, GA US

Patent application numberDescriptionPublished
20120107902Processes For Forming Amide Bonds And Compositions Related Thereto - The disclosure relates to methods for producing amide bonds and reagents related thereto. In some embodiments, the disclosure relates to methods of producing an amide comprising mixing an O-silylated thionoester and an amine under conditions such that an amide is formed. In another embodiment, the disclosure relates to mixing a thiolacid, a silylating agent, and an amine under conditions such that an amide is formed.05-03-2012