Patent application number | Description | Published |
20080230387 | Microfluidic Devices and Methods of Using Same - A variety of elastomeric-based microfluidic devices and methods for using and manufacturing such devices are provided. Certain of the devices have arrays of reaction sites to facilitate high throughput analyses. Some devices also include reaction sites located at the end of blind channels at which reagents have been previously deposited during manufacture. The reagents become suspended once sample is introduced into the reaction site. The devices can be utilized with a variety of heating devices and thus can be used in a variety of analyses requiring temperature control, including thermocycling applications such as nucleic acid amplification reactions, genotyping and gene expression analyses. | 09-25-2008 |
20090176230 | Microfluidic device and methods of using same - A variety of elastomeric-based microfluidic devices and methods for using and manufacturing such devices are provided. Certain of the devices have arrays of reaction sites to facilitate high throughput analyses. Some devices also include reaction sites located at the end of blind channels at which reagents have been previously deposited during manufacture. The reagents become suspended once sample is introduced into the reaction site. The devices can be utilized with a variety of heating devices and thus can be used in a variety of analyses requiring temperature control, including thermocycling applications such as nucleic acid amplification reactions, genotyping and gene expression analyses. | 07-09-2009 |
20090187009 | SCALE-UP METHODS AND SYSTEMS FOR PERFORMING THE SAME - The present invention provides methods of and systems for translating conditions from a small-volume experiment to a larger-volume experiment. | 07-23-2009 |
20100184202 | Thermal Reaction Device and Method for Using the Same - An M×N matrix microfluidic device for performing a matrix of reactions, the device having a plurality of reaction cells in communication with one of either a sample inlet or a reagent inlet through a via formed within an elastomeric block of the device. Methods provided include a method for forming vias in parallel in an elastomeric layer of an elastomeric block of a microfluidic device, the method comprising using patterned photoresist masks and etching reagents to etch away regions or portions of an elastomeric layer of the elastomeric block. | 07-22-2010 |
20110020918 | Microfluidic Assay Devices And Methods - A microfluidic device adapted to perform many simultaneous binding assays including but not limited to immunological experiments, such as ELISA assays, with minimal cross-talk between primary and secondary antibodies. | 01-27-2011 |
20110189678 | Microfluidic Device and Methods of Using Same - A variety of elastomeric-based microfluidic devices and methods for using and manufacturing such devices are provided. Certain of the devices have arrays of reaction sites to facilitate high throughput analyses. Some devices also include reaction sites located at the end of blind channels at which reagents have been previously deposited during manufacture. The reagents become suspended once sample is introduced into the reaction site. The devices can be utilized with a variety of heating devices and thus can be used in a variety of analyses requiring temperature control, including thermocycling applications such as nucleic acid amplification reactions, genotyping and gene expression analyses. | 08-04-2011 |
20130089874 | RECIRCULATING FLUIDIC NETWORK AND METHODS FOR USING THE SAME - The present invention provides a variety of microfluidic devices and methods for conducting assays and syntheses. The devices include a solid substrate layer having a surface that is capable of attaching ligand and or anti-ligand, and an elastomeric layer attached to said surface. Preferred embodiments have deflectable membrane valves and pumps, for example, rotary pumps associated therewith. | 04-11-2013 |
20130171633 | THERMAL REACTION DEVICE AND METHOD FOR USING THE SAME - An M×N matrix microfluidic device for performing a matrix of reactions, the device having a plurality of reaction cells in communication with one of either a sample inlet or a reagent inlet through a via formed within an elastomeric block of the device. Methods provided include a method for forming vias in parallel in an elastomeric layer of an elastomeric block of a microfluidic device, the method comprising using patterned photoresist masks and etching reagents to etch away regions or portions of an elastomeric layer of the elastomeric block. | 07-04-2013 |
20140195103 | ENERGY HARVESTING POWER OUTPUT MEASUREMENT APPARATUS AND METHODS FOR CYCLING - The present teachings provide apparatus and methods for measuring the power output of a person, such as a cyclist. According to various embodiments, while measuring the power output, the present teachings provide for the harvesting of the input energy to provide electrical power to the apparatus. Among others, embodiments are described wherein power measurements are obtained from the drive train of a bicycle by making use of piezoelectric element(s) capable of producing electricity when deformed by applied forces. In addition, telemetry information of the applied forces can be obtained with the use of an inertial measurement unit. | 07-10-2014 |