Hanke, US
Dennis Hanke, Algonquin, IL US
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20110297034 | Railroad Tie Hardware Removing Apparatus and Methods - A railroad tie hardware removing apparatus and methods are provided. The apparatus includes one or more tool mechanisms each carrying one or more tools. The tools are positionable relative to a mounting structure or tower of a concrete railroad tie to remove the tower therefrom. Once the towers are removed, the tie can be pulled from underneath rails supported by the tie. | 12-08-2011 |
20120024189 | High Rail Excavator - A high rail excavator is provided. The high rail excavator includes at least one high rail mechanism to elevate the high rail excavator relative to the rails of a railroad track. The high rail mechanism is disposed within an envelope of the tracks, thereby increasing the maneuverability and safety of the high rail excavator. The high rail mechanism includes a power control arrangement that integrates with a power supply of the excavator so that an additional power supply dedicated to the high rail mechanism is not required. | 02-02-2012 |
20120211571 | Rail Fastening System - A rail fastening system is provided. The rail fastening system includes a fastener including a baseplate and at least one of clamp. The at least one clamp mounts with the baseplate and extends under a rail of a railroad to abut against a flange of the rail opposite a flange adjacent to the baseplate. Certain embodiments of the fastener include adjustment teeth to finely adjust the positioning of the clamps relative to the baseplate. Certain other embodiments of the fastener include slotted clamps that receive a baseplate. | 08-23-2012 |
Jeffrey Herbert Hanke, Reading, MA US
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20080233116 | Human monoclonal antibodies to CTLA-4 - In accordance with the present invention, there are provided fully human monoclonal antibodies against human cytotoxic T-lymphocyte antigen 4 (CTLA-4). Nucleotide sequences encoding and amino acid sequences comprising heavy and light chain immunoglobulin molecules, particularly contiguous heavy and light chain sequences spanning the complementarity determining regions (CDRs), specifically from within FR1 and/or CDR1 through CDR3 and/or within FR4, are provided. Further provided are antibodies having similar binding properties and antibodies (or other antagonists) having similar functionality as antibodies disclosed herein. | 09-25-2008 |
20080233122 | Human monoclonal antibodies to CTLA-4 - In accordance with the present invention, there are provided fully human monoclonal antibodies against human cytotoxic T-lymphocyte antigen 4 (CTLA-4). Nucelotide sequences encoding and amino acid sequences comprising heavy and light chain immunoglobulin molecules, particularly contiguous heavy and light chain sequences spanning the complementarity determining regions (CDRs), specifically from within FR1 and/or CDR1 through CDR3 and/or within FR4, are provided. Further provided are antibodies having similar binding properties and antibodies (or other antagonists) having similar functionality as antibodies disclosed herein. | 09-25-2008 |
20120045442 | HUMAN MONOCLONAL ANTIBODIES TO CTLA-4 - In accordance with the present invention, there are provided fully human monoclonal antibodies against human cytotoxic T-lymphocyte antigen 4 (CTLA-4). Nucelotide sequences encoding and amino acid sequences comprising heavy and light chain immunoglobulin molecules, particularly contiguous heavy and light chain sequences spanning the complementarity determining regions (CDRs), specifically from within FR1 and/or CDR1 through CDR3 and/or within FR4, are provided. Further provided are antibodies having similar binding properties and antibodies (or other antagonists) having similar functionality as antibodies disclosed herein. | 02-23-2012 |
20120148597 | HUMAN MONOCLONAL ANTIBODIES TO CTLA-4 - In accordance with the present invention, there are provided fully human monoclonal antibodies against human cytotoxic T-lymphocyte antigen 4 (CTLA-4). Nucleotide sequences encoding and amino acid sequences comprising heavy and light chain immunoglobulin molecules, particularly contiguous heavy and light chain sequences spanning the complementarity determining regions (CDRs), specifically from within FR1 and/or CDR1 through CDR3 and/or within FR4, are provided. Further provided are antibodies having similar binding properties and antibodies (or other antagonists) having similar functionality as antibodies disclosed herein. | 06-14-2012 |
20140099325 | HUMAN MONOCLONAL ANTIBODIES TO CTLA-4 - In accordance with the present invention, there are provided fully human monoclonal antibodies against human cytotoxic T-lymphocyte antigen 4 (CTLA-4). Nucleotide sequences encoding and amino acid sequences comprising heavy and light chain immunoglobulin molecules, particularly contiguous heavy and light chain sequences spanning the complementarity determining regions (CDRs), specifically from within FR1 and/or CDR1 through CDR3 and/or within FR4, are provided. Further provided are antibodies having similar binding properties and antibodies (or other antagonists) having similar functionality as antibodies disclosed herein. | 04-10-2014 |
20150104409 | HUMAN MONOCLONAL ANTIBODIES TO CTLA-4 - In accordance with the present invention, there are provided fully human monoclonal antibodies against human cytotoxic T-lymphocyte antigen 4 (CTLA-4). Nucleotide sequences encoding and amino acid sequences comprising heavy and light chain immunoglobulin molecules, particularly contiguous heavy and light chain sequences spanning the complementarity determining regions (CDRs), specifically from within FR1 and/or CDR1 through CDR3 and/or within FR4, are provided. Further provided are antibodies having similar binding properties and antibodies (or other antagonists) having similar functionality as antibodies disclosed herein. | 04-16-2015 |
Jeffrey S. Hanke, Rhinelander, WI US
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20130019728 | Method and apparatus for forming paired stiles and rails - The invention is for a method for making precise pairs of rails and stiles for doors and the apparatus for practicing the method. The method teaches cutting profiles into the perimeter of a workpiece and then cutting the workpiece in two to form two identical rails or stiles. The method teaches the use of a flat and true base having a flat and true fence along which a workpiece is moved into positions to cut profiles in the perimeter of the workpiece and then to cut the workpiece along its centerline into two identical rails or stiles. | 01-24-2013 |
John Hanke, Schertz, TX US
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20090049609 | SYSTEM AND METHOD TO OCCLUDE PATIENT ENTRAPMENT ZONES - A system and method for occluding potential entrapment zones in a bed. The system includes a head-end assembly with a head-end cover enclosing a head-end pad and a pair of reinforcing end members. The system also includes a torso assembly, a leg assembly and a foot-end assembly with covers enclosing pads and reinforcing members. | 02-26-2009 |
20090049614 | SYSTEM AND METHOD TO OCCLUDE PATIENT ENTRAPMENT ZONES - A system and method for occluding potential entrapment zones in a bed. The system includes a head-end assembly with a head-end cover enclosing a head-end pad, and a torso assembly with a pair of covers each enclosing a pair of pads. The system also includes a leg assembly with a cover enclosing pads and a foot-end assembly with covers enclosing pads. The system further includes multiple sets of coupling members that couple the covers together. | 02-26-2009 |
20090144908 | SYSTEM AND METHOD TO OCCLUDE PATIENT ENTRAPMENT ZONES - A system and method for occluding potential entrapment zones in a bed. The system may include a head-end assembly with a head-end cover enclosing a head-end pad, and a foot-end assembly with covers enclosing pads. The system may further include a pair of walls extending between the head-end assembly and the foot-end assembly. The walls may include inflatable members. | 06-11-2009 |
Linda A. Hanke, Phoenix, AZ US
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20110079527 | CONTAINER WRAP AND CONTAINER FORMED THEREWITH - A container has an upstanding sidewall with opposed outer and inner surfaces extending between a bottom, having an upper surface and a lower surface, and an opposed top formed by an upper edge encircling a first opening having a first diameter and that leads to a receptacle formed by and between the upper surface of the bottom and the inner surface of the sidewall. A sheet of thin, flexible material is applied over and across the lower surface of the bottom and the outer surface of the sidewall and over and across the upper edge of the container terminating with a peripheral extremity that extends inboard with respect to the upper edge of the container encircling a second opening having a second diameter less than the first diameter of the first opening and that leads to the receptacle and that is substantially concentric with respect to the first opening. | 04-07-2011 |
Paul Hanke, Urbana, IL US
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20130116138 | PEPTIDE DOMAINS THAT BIND SMALL MOLECULES OF INDUSTRIAL SIGNIFICANCE - Described herein are small peptide domains and consensus sequences that bind small target molecules of industrial importance, e.g., metals such as nickel, β carotene, and isoflavones such as genistein. Also described are fusion proteins containing such binding domains fused to proteins or to peptide domains like GST or GBD that bind other ligands and can be used to immobilize the target binding domain on a support. One class of fusion proteins that is useful in industrial settings are fusions that contain concatemers of target binding domains, which increases the binding equivalents per molecule. | 05-09-2013 |
Paul D. Hanke, Urbana, IL US
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20090053780 | Enzymatic oxidation of HMF - A method of converting hydroxymethylfurfural and is derivative species into hydroxymethylfurfural oxidation products is disclosed. The method includes contacting the hydroxymethylfurfural species in a mixture with an enzyme that oxidizes the hydroxymethylfurfural species while controlling hydrogen peroxide in the mixture. In one exemplary embodiment the enzyme is chloroperoxidase and the hydrogen peroxide is metered into the mixture to predominantly and selectively make at least one of formylfuran carboxylic acid or furan dicarboxylic acid. In another embodiment the enzyme is aryl alcohol oxidase and catalase is included in the mixture to remove unwanted hydrogen peroxide by product and the reaction predominantly makes at least one of dimethylfuran or formylfuran carboxylic acid. When the predominant product is a carboxylic acid or furan dicarboxylic acid, it can be recovered in substantially pure form by acid precipitation. | 02-26-2009 |
20090081740 | PRODUCTION OF AMINO ACIDS FROM SUCROSE IN CORYNEBACTERIUM GLUTAMICUM - Methods and compositions for increased production of amino acids from | 03-26-2009 |
20110045549 | POLYNUCLEOTIDES ENCODING A FEEDBACK RESISTANT ASPARTOKINASE FROM CORYNEBACTERIUM - The invention provides methods to increase the production of an amino acid from | 02-24-2011 |
Stepan Hanke, Lake Orion, MI US
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20150337566 | MOTOR VEHICLE DOOR LOCK ARRANGEMENT - The invention relates to a motor vehicle door lock arrangement with a motor vehicle lock wherein a force transmission chain is provided and wherein an actuation movement may be transmitted via the force transmission chain for opening of the motor vehicle lock, wherein a crash coupling arrangement is provided between two force transmission chain sections, which comprises a deflectable coupling element, wherein the coupling element is at least partly bendable. | 11-26-2015 |
Tomas Hanke US
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20110177115 | VACCINATION REGIMEN - The present invention provides a method of raising an immune response in a subject against an antigen. The method involves the steps of a) administering to the subject a non-atadenoviral vector comprising a nucleic acid encoding the antigen, and b) administering an engineered atadenovirus to the subject, wherein the genome of the engineered atadenovirus encodes the antigen. Step b) is performed after step a). | 07-21-2011 |