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Handa, US

James T. Handa, Baltimore, MD US

Patent application numberDescriptionPublished
20110106102Surgical Instrument and Systems with Integrated Optical Sensor - A surgical instrument has a surgical tool that has a proximal end and a distal end, and an optical sensor that has at least a portion attached to the surgical tool. The surgical tool has a portion that is suitable to provide a reference portion of the surgical tool, and the optical sensor has an end fixed relative to the reference portion of the surgical tool such that the reference portion of the surgical tool can be detected along with tissue that is proximate or in contact with the distal end of the surgical tool while in use.05-05-2011
20110125165SYSTEM AND METHOD FOR MACRO-MICRO DISTAL DEXTERITY ENHANCEMENT IN MICRO-SURGERY OF THE EYE - A system for operating within an interior region of the eye, or other organ, includes a delivery channel having a proximal portion located exterior to the eye and a distal portion positionable within the interior region of the eye, wherein the distal portion of the delivery channel defines an outer diameter that is smaller than or equal to about 18 gauge, and a micro-robot extendable from the distal portion of the delivery channel, wherein the micro-robot is remotely operable to change shape within the interior region of the eye.05-26-2011

Kazuko Handa, Bellevue, WA US

Patent application numberDescriptionPublished
20110142844Anti-Extended Type I Glycosphingolipid Antibody, Derivatives Thereof And Use - Human antibodies and antigen-binding portions of those antibodies that specifically bind extended Type I chain glycosphingolipids are provided.06-16-2011

Keith T. Handa, San Clemente, CA US

Patent application numberDescriptionPublished
20110092924CONTROLLING OF MULTIPLE PUMPS - An apparatus for controlling vacuum pressure is provided. The apparatus includes a multiple axis controller, such as a dual axis footpedal, and a processing apparatus, such as an instrument host running software, configured to receive multiple axis data from the multiple axis controller. The apparatus also includes a first pump configured to provide nonzero fluid pressure at a first nonzero fluid pressure level based on a first axis state of the multiple axis controller and a second pump configured to provide nonzero fluid pressure at a second nonzero fluid pressure level based on a second axis state of the multiple axis controller. The processing apparatus causes switching between the first pump and the second pump based on the first axis state and the second axis state of the multiple axis controller.04-21-2011

Masahisa Handa, Berkeley, CA US

Patent application numberDescriptionPublished
20090142261EPHB3-Specific Antibody and Uses Thereof - EphB3-specific antibodies are provided, along with pharmaceutical compositions containing such antibody, kits containing a pharmaceutical composition, and methods of preventing and treating cancer.06-04-2009

Patent applications by Masahisa Handa, Berkeley, CA US

Neerav Handa, Sunnyvale, CA US

Patent application numberDescriptionPublished
20100042518PAYROLL RULES ENGINE FOR POPULATING PAYROLL COSTING ACCOUNTS - Systems and methods are disclosed for using rules to populate a payroll cost account. An embodiment includes receiving a request to create a new payroll rule, displaying a rule creation user interface to a user, receiving a rule definition for the new payroll rule, generating the new payroll rule, and applying the payroll rule to payroll data.02-18-2010
20100198707Replicating Data in Financial Systems - Systems and methods for replicating data communicated over a network. According to one embodiment, among several embodiment, a data replication system includes a first interface table and a first application associated with a first computing system. The first application is configured to transfer data into the first interface table. The data replication system further includes a first replication module, which is also associated with the first computing system. The first replication module is configured to replicate data from the first interface table into a second interface table associated with a second computing system via a network. The data replication system also includes a second application and a second replication module associated with the second computing system. The second application is configured to transfer data into the second interface table. The second replication module is configured to replicate data from the second interface table into the first interface table via the network. Furthermore, the data replication system includes a web service module configured to check the contents of the second interface table before the first application performs a specific processing operation.08-05-2010

Robert J. Handa, Fort Collins, CO US

Patent application numberDescriptionPublished
20100087519USE OF EQUOL FOR TREATING ANDROGEN MEDIATED DISEASES - Equol (7-hydroxy-3(4′hydroxyphenyl)-chroman), the major metabolite of the phytoestrogen daidzein, specifically binds and blocks the hormonal action of 5α-dihydrotestosterone (DHT) in vitro and in vivo. Equol can bind circulating free DHT and sequester it from the androgen receptor, thus altering growth and physiological hormone responses that are regulated by androgens. These data suggest a novel model to explain equol's biological properties. The significance of equol's ability to specifically bind and sequester DHT from the androgen receptor have important ramifications in health and disease and may indicate a broad and important usage for equol in the treatment and prevention of androgen-mediated pathologies. Thus, equol can specifically bind DHT and prevent DHT's biological actions in physiological and pathophysiological processes.04-08-2010

Patent applications by Robert J. Handa, Fort Collins, CO US

Robert J. Handa, Phoenix, AZ US

Patent application numberDescriptionPublished
20100076071USE OF EQUOL FOR TREATING SKIN DISEASES - Equol (7-hydroxy-3(4′hydroxyphenyl)-chroman), the major metabolite of the phytoestrogen daidzein, specifically binds and blocks the hormonal action of 5α-dihydrotestosterone (DHT) in vitro and in vivo. Equol can bind circulating free DHT and sequester it from the androgen receptor, thus altering growth and physiological hormone responses that are regulated by androgens. These data suggest a novel model to explain equol's biological properties. The significance of equol's ability to specifically bind and sequester DHT from the androgen receptor have important ramifications in health and disease and may indicate a broad and important usage for equol in the treatment and prevention of androgen-mediated pathologies of skin and hair. Thus, equol can specifically bind DHT and prevent DHT's biological actions in physiological and pathophysiological processes affecting skin and hair.03-25-2010

Y. Paul Handa, Pittsford, NY US

Patent application numberDescriptionPublished
20090123728Polymer Blends Of Biodegradable Or Bio-Based And Synthetic Polymers And Foams Thereof - The present invention relates to compositions comprising blends of alkenyl aromatic polymers such as styrenic polymers (i.e. PS and HIPS) and bio-based or biodegradable polymers (i.e. PLA, PGA, PHA, PBS, PCL) compatibilized with styrene-based copolymers (i.e. styrene-ethylene-butylene-styrene (SEBS) block copolymers, maleated SEBS, styrene-maleic anhydride (SMA) copolymer, styrene-methyl methacrylate (SMMA) copolymer) or a mixture of two or more styrene-based copolymers such as SEBS and SMA. These novel compositions can be extruded and thermoformed to produce very low density food service and consumer foam articles such as plates, hinged lid containers, trays, bowls, and egg cartons with good mechanical properties.05-14-2009

Patent applications by Y. Paul Handa, Pittsford, NY US