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Hammond, MA
Charles Hammond, Burlington, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20110021513 | MODULATORS OF INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE - The present invention relates to modulators of IRAK kinase and provides compositions comprising such modulators, as well as methods therewith for treating conditions or diseases mediated by or associated with IRAK kinase. | 01-27-2011 |
Charles E. Hammond, Billerica, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090148396 | BIOCOMPATIBLE BIODEGRADABLE FUMAGILLIN ANALOG CONJUGATES - Fumagillin analog polymer conjugates, methods of making fumagillin analog polymer conjugates, compositions comprising a polymer conjugate of a fumagillin analog, and methods for treating cancer, or treating angiogenic diseases comprising administering to a subject in need thereof an effective amount of a polymer conjugate of a fumagillin analog, are described. Also described are novel fumagillin analogs, methods of making fumagillin analogs, compositions comprising at least one fumagillin analog, and methods for treating cancer, or treating angiogenic diseases comprising administering to a subject in need thereof an effective amount of a fumagillin analog. | 06-11-2009 |
| 20100305149 | Polyal Drug Conjugates Comprising Variable Rate-Releasing Linkers - Polyal-Drug conjugates comprising a variable rate-releasing linker are described along with methods of making such conjugates. Uses for such Polyal-Drug conjugates is also described. | 12-02-2010 |
Matthew Patrick Hammond, Boston, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100128369 | Optical Package Comprising an Adjustable Lens Component Coupled to a Multi-Directional Lens Flexure - An optical package is provided comprising a lens system, the lens system comprising an adjustable lens component, a plurality of magnetic elements, and a multi-directional lens flexure. The adjustable lens component is mechanically coupled to a lens mounting portion of the multi-directional lens flexure. The magnetic elements comprise at least one fixed magnetic element and at least one motive magnetic element. The arrangement of the fixed and motive magnetic elements relative to each other forms a first fixed/motive element pair and a second fixed/motive element pair. The motive magnetic element of each fixed/motive element pair is mechanically coupled to a motive portion of the multi-directional lens flexure. The structure of the multi-directional lens flexure and the arrangement of the fixed/motive element pairs is such that non-orthogonal repulsive or attractive magnetic force vectors generated between magnetic elements of the respective fixed/motive element pairs generate movement of the adjustable lens component through orthogonal components x, y along X and Y axes of the X-Y optical reference frame. | 05-27-2010 |
Paula T. Hammond, Newton, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20080311177 | Self Assembled Films for Protein and Drug Delivery Applications - Provided are systems for controlled release of proteins from decomposable thin films constructed by layer-by-layer deposition. Such films generally comprise alternating layers of polymers and proteins, and may further comprise additional layers of polyions. In some embodiments, decomposable thin films and methods of using such films allow proteins to be released over an extended period of time and/or retention of as much as 100% of function of released protein. | 12-18-2008 |
| 20090197138 | Highly Conducting Solid State Ionics for Electrochemical Systems and Methods of Fabricating Them Using Layer-by-Layer Technology - Herein are disclosed methods, and compositions produced using them, to assemble highly conducting, hydrolytically stable polymer electrolyte films from commercially-available, water-soluble polymers using layer-by-layer assembly technology. In certain embodiments, these films can be used for electrochemical device applications which require an ion-conducting material to operate. For example, the power efficiency of any electrochemical device with a solid polymer electrolyte layer can be increased by this technology by virtue of the low ionic resistance of these layer-by-layer assembled thin film electrolytes. Specifically, direct-methanol operated fuel cells (DMFCs) should benefit remarkably, as the described technology offers very high conductivity values at fully hydrated conditions with low fuel (methanol) crossover. | 08-06-2009 |
| 20100003499 | Automated layer by layer spray technology - The present invention comprises an automated apparatus capable of spray depositing polyelectrolytes via the LbL mechanism with minimal or no human interaction. In certain embodiments, the apparatus sprays atomized polyelectrolytes onto a vertically oriented substrate. To counteract the effects of irregular spray patterns, the substrate is preferably slowly rotated about a central axis. In certain embodiments, the apparatus also includes a forced pathway for the droplets, such as a pathway created by using a vacuum. In this way, a thicker or three-dimensional substrate can be coated. In certain embodiments, the apparatus is designed so as to be scalable. Thus, through the use of multiple instantiations of the apparatus, a large or irregularly shaped substrate can be coated. Rolls of textile can therefore be coated using the apparatus. Additionally, the present invention includes a method to uniformly coat a substrate, such as a hydrophobic textile material, using aqueous solutions of polyelectrolytes. | 01-07-2010 |
| 20100130082 | Highly Reactive Multilayer Assembled Coating of Metal Oxides on Organic and Inorganic Substrates - One aspect of the invention relates to a method of preparing metal oxide coated substrates for various potential applications, and the coated substrate formed thereby. | 05-27-2010 |
| 20110097419 | Poly(Propargyl-L-Glutamate) and Derivatives Thereof - A process of the present invention is directed toward conducting highly selective, high yield post-polymerization reactions on polypeptides to prepare functionalized polypeptides. In certain embodiments, the polypeptides can be prepared by ring opening polymerization of N-carboxyanhydrides. In certain embodiments, the post-polymerization reaction is a “click chemistry” reaction. In certain embodiment, the “click chemistry” reaction is a triazole-forming reaction involving an alkyne on the polypeptide and an azide. | 04-28-2011 |
Richard Hammond, Cambridge, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100264995 | RF Circuits Including Transistors Having Strained Material Layers - Circuits for processing radio frequency (“RF”) and microwave signals are fabricated using field effect transistors (“FETs”) that have one or more strained channel layers disposed on one or more planarized substrate layers. FETs having such a configuration exhibit improved values for, for example, transconductance and noise figure. RF circuits such as, for example, voltage controlled oscillators (“VCOs”), low noise amplifiers (“LNAs”), and phase locked loops (“PLLs”) built using these FETs also exhibit enhanced performance. | 10-21-2010 |
Tyler Christian Hammond, Arlington, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20110189718 | Systems And Methods For Segregating Mixed Material Streams - The invention relates to methods and systems of detecting useful material in a mixed solid, liquid and/or gaseous material stream. The methods include defining a value range requirement for at least one parameter of interest of useful material to be selected from the material stream, passing the material stream through at least one detector adapted to measure the parameter of interest of the material stream, and separating the material stream into useful material and residue based on the measured parameter. The systems comprise at least one detector adapted to measure a parameter of interest of the material stream passing therethrough; and at least one separator for separating the material stream into useful material and residue based on the measured parameter after passing through the detector. The system may further comprise treaters, processors, and controllers. | 08-04-2011 |