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Hallahan, US
David L. Hallahan, Wilmington, DE US
| Patent application number | Description | Published |
|---|---|---|
| 20090288226 | Method for manipulating growth, yield, and architecture in plants - This invention pertains to a method for manipulating the growth rate and/or yield and/or architecture of a genetically modified plant, as compared to a corresponding wild-type plant. The method relies on over-expression of an endogenous or exogenous gene encoding a cis-prenyltransferase enzyme. In a preferred embodiment, transgenic plants obtained by this method exhibit increased growth rates to maturity, increased seed production, and increased height, siliques, and leave area. | 11-19-2009 |
| 20100034754 | METHOD FOR MAKING INSECT REPELLENT COMPOSITION - Dihydronepetalactone, a minor natural constituent of the essential oil of catmints ( | 02-11-2010 |
Dennis E. Hallahan, Nashville, TN US
| Patent application number | Description | Published |
|---|---|---|
| 20080206130 | IN VIVO PANNING FOR LIGANDS TO RADIATION-INDUCED MOLECULES - A method for identifying a molecule that binds an irradiated tumor in a subject and molecules identified thereby. The method includes the steps of: (a) exposing a tumor to ionizing radiation; (b) administering to a subject a library of diverse molecules; and (c) isolating from the tumor one or more molecules of the library of diverse molecules, whereby a molecule that binds an irradiated tumor is identified. Also provided are therapeutic and diagnostic methods using targeting ligands that bind an irradiated tumor. | 08-28-2008 |
| 20080262286 | SPECIFIC INHIBITION OF CPLA2 ENHANCES THE EFFICACY OF RADIOTHERAPY - A method for increasing the radiosensitivity of a target tissue in a subject is disclosed. In some embodiments, the methods includes administering a cytosolic phospholipase A2 (cPLA | 10-23-2008 |
| 20090041863 | Use of GSK3 inhibitors in combination with radiation therapies - The presently disclosed subject matter relates generally to the fields of molecular biology and medicine. More particularly, it concerns methods involving the use of GSK3 inhibitors in combination with radiation therapies. In some embodiments, administration of a GSK3 inhibitor to a subject results in an amelioration of cognitive decline, toxicity to vascular endothelial cells, and/or neuron death associated with radiation therapy alone. | 02-12-2009 |
| 20090136487 | BMX MEDIATED SIGNAL TRANSDUCTION IN IRRADIATED VASCULAR ENDOTHELIUM - Provided are methods for modulating the proliferation of cells and tissues. In some embodiments, the methods include administering to a subject an effective amount of a modulator of a biological activity of a bone marrow X kinase (Bmx) gene product. Also provided are methods for increasing the radiosensitivity of a target cell or tissue, methods for suppressing tumor growth, methods for inhibiting tumor blood vessel growth, and compositions that include modulators of a biological activity of a bone marrow X kinase (Bmx) gene product. | 05-28-2009 |
| 20100135905 | ASSESSMENT OF CANCER SUSCEPTIBILITY TO MOLECULAR TARGETED THERAPY BY USE OF RECOMBINANT PEPTIDES - A method for assessing cancer susceptibility to molecular targeted therapy. Also provided are methods for in vivo panning of diverse molecules for isolation of targeting ligands that specifically bind an apoptotic cell associated with a responding tumor, targeting ligands identified by the panning methods, and diagnostic and imaging uses therefor. | 06-03-2010 |
Dennis E. Hallahan, St. Louis, MO US
| Patent application number | Description | Published |
|---|---|---|
| 20110213293 | LIGANDS TO RADIATION-INDUCED MOLECULES - A method for identifying a molecule that binds an irradiated tumor in a subject and molecules identified thereby. In some embodiments, the method includes the steps of (a) exposing a tumor to ionizing radiation; (b) administering to a subject a library of diverse molecules; and (c) isolating from the tumor one or more molecules of the library of diverse molecules, whereby a molecule that binds an irradiated tumor is identified. Also provided are targeting ligands that bind an irradiated tumor and therapeutic and diagnostic methods that employ the disclosed targeting ligands. | 09-01-2011 |
Dennis F. Hallahan, Old Lyme, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20100329787 | Corrugated Leaching Chamber with Hollow Pillar Supports - A plastic leaching chamber has an arch shape cross section, corrugations, and one or more hollow pillars extending downwardly within the interior of the chamber, to support the top of the chamber when the chamber is under load during use. Chambers nest within one another to form a stack of chambers for transport or storage. Chambers have peak corrugations which are substantially wider than the intervening valley corrugations. Chambers having different widths and profiles have common size connectors. | 12-30-2010 |
| 20110020065 | Leaching chamber having pillars and wide peak corrugations - A plastic leaching chamber has an arch shape cross section, corrugations, and one or more hollow pillars extending downwardly within the interior of the chamber, to support the top of the chamber when the chamber is under load during use. Chambers nest within one another to form a stack of chambers for transport or storage. Chambers have peak corrugations which are substantially wider than the intervening valley corrugations. Chambers having different widths and profiles have common size connectors. | 01-27-2011 |