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Halenbeck
Forgan Robert Halenbeck, San Rafael, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20080242603 | Novel Apo2L and IL-24 Polypeptides, Polynucleotides, and Methods of Their Use - Disclosed are newly identified Interleukin 24 and APO2L splice variant molecules, their polypeptide sequences, and the polynucleotides encoding the polypeptide sequences. Also provided is a procedure for producing such polypeptides by recombinant techniques employing, for example, vectors and host cells, and, for example, heterologous secretory leader sequences. Also disclosed are methods for using such polypeptides and modulators thereof for the treatment of diseases, including cancer, immune diseases, infectious diseases, and ischemic diseases. | 10-02-2008 |
Robert F. Halenbeck, San Rafael, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20080281084 | Formulation, Solubilization, Purification, and Refolding of Tissue Factor Pathway Inhibitor - Compositions are described that are suitable for formulating TFPI. Solubilizers and stabilizers facilitate the preparation of pharmaceutically acceptable compositions of TFPI at various concentrations. | 11-13-2008 |
Robert Forgan Halenbeck, San Francisco, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20080286834 | Leader Sequences For Directing Secretion of Polypeptides and Methods For Production Thereof - The present invention provides leader sequences that are useful for the production of heterologous secretable polypeptides; heterologous secreted polypeptides; nucleic acid constructs that encode such leader sequences and heterologous secreted polynucleotides; vectors that contain such nucleic acid constructs; recombinant host cells that contain such nucleic acid constructs; vectors, polypeptides, and methods of making and using such secreted polypeptides with such heterologous leader sequences. | 11-20-2008 |
| 20110003384 | COMPOSITIONS AND METHODS OF USE FOR MGD-CSF IN DISEASE TREATMENT - Disclosed is a newly identified secreted molecule, identified herein as “monocyte, granulocyte, and dendritic cell colony stimulating factor” (MGD-CSF), the polypeptide sequence, and polynucleotides encoding the polypeptide sequence. Also provided is a procedure for producing the polypeptide by recombinant techniques employing, for example, vectors and host cells. Additionally, procedures are described to modify the disclosed novel molecules of the invention to prepare fusion molecules. Also disclosed are methods for using the polypeptides and active fragments thereof for treatment of a variety of diseases, including, for example, cancer, autoimmune and inflammatory diseases, infectious diseases, and recurrent pregnancy loss. | 01-06-2011 |