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Hagen Bartossek, Sachsen-Anhalt DE
| Patent application number | Description | Published |
|---|---|---|
| 20110269930 | INCREASED MONOMER CONVERSION IN EMULSION POLYMERIZATION - A method for increasing the monomer conversion in a redox initiated emulsion polymerization has been discovered. The method comprises adding a composition comprising an effective amount of a substituted phenol to the polymerization medium. In this manner, high monomer conversion is obtained and the product has low gel contents and a low amount or no crosslinking. | 11-03-2011 |
Hagen Bartossek, Schkopau DE
| Patent application number | Description | Published |
|---|---|---|
| 20110123746 | OIL EXTENDED RUBBER COMPOSITIONS - The present invention describes a composition comprising a diene-based rubber and at least one cyclo-aliphatic epoxide-based polyether or polyglycol ether. The present invention also describes a composition comprising at least one extending oil and at least one cyclo-aliphatic epoxide-based polyether or polyglycol ether, wherein the at least one extending oil is selected from the group consisting of an aromatic oil, an aliphatic oil, a naphthenic oil, and mixtures thereof. | 05-26-2011 |
| 20110178256 | STYRENE-BUTADIENE POLYMERS WITH STYRENE GRADIENT AND METHODS OF MAKING THE SAME - The invention provides a process for polymerizing a polymer comprising monomeric units derived from styrene and 1,3-butadiene, said process comprising: A) adding less than 60 weight percent of the total amount of the butadiene used in the polymerization, to a reactor comprising the total amount of styrene used in the polymerization and solvent; B) initiator to the reactor, and allowing the reaction to proceed for a time t; C) adding the remaining amount of butadiene to the reactor in two or more separate additions; and wherein for each burtadiene addition, the amount of subsequent butadiene added is less than, or equal to, the amount of butadiene added in the immediately prior addition; and wherein for each butadiene addition, the butadiene is added over a time, t | 07-21-2011 |
Hagen Deyhle, Weissach DE
| Patent application number | Description | Published |
|---|---|---|
| 20110024203 | MOTOR VEHICLE - A hybrid drive for motor vehicle has at least one combustion engine, an electric machine and an electric energy accumulator ( | 02-03-2011 |
Hagen Doepfert, Lindau DE
| Patent application number | Description | Published |
|---|---|---|
| 20120083384 | PLANETARY GEARBOX HAVING NESTED PLANETARY GEAR STAGES - A planetary gearbox, for an automatic transmission of a motor vehicle, comprising two stages, each provided with a sun gear, a ring gear and interposed planetary gears. The ring gear of the first planetary stage also forms the sun gear of the second stage, and the planetary gears of both stages are guided by a common planet carrier, produced from a casting material, which accommodates the planetary gears of the first stage at an axial offset position to the planetary gears of the second stage. The planet carrier is designed as one-piece such that pockets are respectively disposed in the planet carrier for receiving the planetary gears of the first stage at an offset angle, in the circumferential direction, to the pockets for receiving the planetary gears of the second stage, so that it is possible to form the pockets during casting using slides. | 04-05-2012 |
Hagen Dopfert, Lindau DE
| Patent application number | Description | Published |
|---|---|---|
| 20080269004 | Multi-Speed Transmission - The 8-stage transmission possesses one input and one output shaft (AN, AB), four planetary gearsets (RS | 10-30-2008 |
| 20090247348 | PLANETARY TRANSMISSION - A planetary gear set lubricating unit which supplies oil from inside a component adjacent the planetary gear set, via a radial bore and an oil catcher, axially through a bore of a planetary gear bolt to planetary gear bearings. The oil catcher forms a ring-shaped chamber, which can be filled with lubricant, and is arranged beside the planetary carrier approximately over the reference diameter of the planetary bolt. The oil catcher has outlet pipes extending axially to direct oil in the chamber. The oil catcher has ovular radial protrusions arranged such that a maximum radial dimension is close to the bolts and a minimum radial dimension is arranged between adjacent planetary bolts. The radially inner edge of the axial bore of the planetary bolts is radially located between the minimum and maximum dimensions of the protrusions. The chamber is delimited by a cover plate and a gasket. | 10-01-2009 |
Hagen DÖpfert, Lindau DE
| Patent application number | Description | Published |
|---|---|---|
| 20110278132 | PARKING LOCK DEVICE FOR AN AUTOMATIC TRANSMISSION OF A MOTOR VEHICLE - A parking lock device ( | 11-17-2011 |
Hagen Federau, Meersburg DE
| Patent application number | Description | Published |
|---|---|---|
| 20080239270 | OPTICAL ELEMENT MODULE - An optical element module comprising a plurality of module components is provided. The module components comprise an optical element, an optical element holder and a contact element. The optical element has a first coefficient of thermal expansion. The optical element holder holds the optical element via the first contact element and has a second coefficient of thermal expansion, the second coefficient of thermal expansion being different from the first coefficient of thermal expansion. At least one of the module components is adapted to provide at least a reduction of forces introduced into the optical element upon a thermally induced position change in the relative position between the optical element and the optical element holder, the position change resulting from a temperature situation variation in a temperature situation of the plurality of module components. | 10-02-2008 |
| 20110063590 | OPTICAL ELEMENT MODULE - An optical element module comprising a plurality of module components is provided. The module components comprise an optical element, an optical element holder and a contact element. The optical element has a first coefficient of thermal expansion. The optical element holder holds the optical element via the first contact element and has a second coefficient of thermal expansion, the second coefficient of thermal expansion being different from the first coefficient of thermal expansion. At least one of the module components is adapted to provide at least a reduction of forces introduced into the optical element upon a thermally induced position change in the relative position between the optical element and the optical element holder, the position change resulting from a temperature situation variation in a temperature situation of the plurality of module components. | 03-17-2011 |
Hagen Federau, Augsburg DE
| Patent application number | Description | Published |
|---|---|---|
| 20080204689 | Optical module with minimized overrun of the optical element - There is provided an optical module for microlithography. The optical module includes an optical element and a retaining device for holding the optical element. The optical element has (a) a main extension plane, in which it defines a radial direction R and a circumferential direction U, and (b) a free optical diameter and an overrun in the region of its outer periphery. The retaining device contacts the optical element in the region of the overrun, and is formed and/or contacts the optical element in such a manner that the overrun ratio, calculated from the overrun related to a minimum overrun necessary for the production of the optical element, is at most 1.5. | 08-28-2008 |
| 20090147229 | Optical element unit and method of supporting an optical element - There is provided an optical element unit comprising an optical element, a connector element, and an optical element holder. The optical element has a plane of main extension as well as an outer circumference and defines a radial direction. The connector element connects the optical element and the optical element holder, the connector element having a first connector part connected to the optical element at the outer circumference and a second connector part connected to the optical element holder. The first connector part and the second connector part are connected via at least one coupling part, the coupling part being compliant in the radial direction and substantially preventing rotation between the first connector part and the second connector part in a plane substantially parallel to the plane of main extension. | 06-11-2009 |
Hagen Gerecke, Jena DE
| Patent application number | Description | Published |
|---|---|---|
| 20090054387 | Method for preparing 4-[17beta-methoxy-17alpha-methoxymethyl-3-oxestra-4,9-dien-11beta-yl]benz- aldehyde (E)-oxime (asoprisnil) - The present invention relates to a method for the reliable and reproducible preparation of 4-[17β-methoxy-17α-methoxymethyl-3-oxoestra-4,9-dien-11β-yl]benzaldehyde (E)-oxime (asoprisnil) on the pilot and manufacturing scale. Asoprisnil, which is prepared by this method, is distinguished by a very good physical stability and is therefore particularly suitable for the manufacture of solid pharmaceutical forms (tablets, coated tablets, etc.). | 02-26-2009 |
| 20110257142 | METHOD FOR PREPARING 4-[17BETA-METHOXY-17ALPHA-METHOXYMETHYL-3-OXOESTRA-4,9-DIEN-11-BETA-YL]BE- NZALDEHYDE (E)-OXIME (ASOPRISNIL) - The present invention relates to a method for the reliable and reproducible preparation of 4-[17β-methoxy-17α-methoxymethyl-3-oxoestra-4,9-dien-11β-yl]benzaldehyde (E)-oxime (asoprisnil) on the pilot and manufacturing scale. Asoprisnil, which is prepared by this method, is distinguished by a very good physical stability and is therefore particularly suitable for the manufacture of solid pharmaceutical forms (tablets, coated tablets, etc.). | 10-20-2011 |
Hagen Gottlich, Pfafers CH
| Patent application number | Description | Published |
|---|---|---|
| 20110252969 | HOT-TRAP ASSEMBLY FOR TRAPPING UNREACTED GAS BY- PRODUCTS - The present invention provides a hot-trap device ( | 10-20-2011 |
Hagen Graebner, Ingelheim DE
| Patent application number | Description | Published |
|---|---|---|
| 20100215590 | Micronization Method - The invention relates to a method for producing a micronized, virtually anhydrous form of (1α,2β,4β,5α,7β)-7-[(hydroxydi-2-thienylacetyl)oxy]-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.0 | 08-26-2010 |
Hagen Hertsch, Erlangen DE
| Patent application number | Description | Published |
|---|---|---|
| 20090202194 | OPTICAL MEASURING DEVICE FOR DETERMINING TEMPERATURE IN A CRYOGENIC ENVIRONMENT AND WINDING ARRANGEMENT WHOSE TEMPERATURE CAN BE MONITORED - An optical measuring device for determining temperature in a cryogenic environment includes at least one optical waveguide provided with at least one fiber Bragg grating sensor that is interrogated by a light signal. The device includes a light injector that injects light into the at least one fiber Bragg grating sensor, and an evaluation unit that determines a temperature value from the modulated light signal emanating from the at least one fiber Bragg grating sensor. The device includes at least one jacket that non-rigidly encloses the optical waveguide, at least in the region of the at least one fiber Bragg grating sensor. The jacket has a larger coefficient of thermal expansion, at least at cryogenic temperatures, than the optical waveguide. A winding arrangement for use in a cryogenic environment is provided with such a device for temperature monitoring of a conductor of the winding arrangement. | 08-13-2009 |
| 20100208247 | Quality assurance testing for rotor blades of a wind energy installation - To check whether the glass fiber or carbon fiber mats in a rotor blade for a wind energy installation have faults, upward bulges or folds after they have been manufactured, a point or line laser is directed at an angle onto the surface of the rotor blade. From the position of the reflected beam, especially a proportion of the beam that is reflected below the surface of the rotor blade at the mat, the location and form of the mat is deduced and it is determined in a non-destructive manner whether faults, upward bulges or folds are present. | 08-19-2010 |
Hagen Keiner, Muenchen DE
| Patent application number | Description | Published |
|---|---|---|
| 20110168960 | DEVICE AND METHOD FOR CONTROLLING A PRESTRESSING JACK WHEN TENSIONING A TENDON - A device and a method for controlling a clamping press is provided when clamping a tension member as a function of the clamping force of a reference clamping member. The device has a hollow, cylindrical housing, wherein a piston coupled to the reference tension member is supported longitudinally displaceably along an axis. The housing and the piston encompass a pressure chamber that can be acted upon by a pressure medium for performing an axial stroke motion of the piston against the clamping force of the reference tension member by an inlet, and that can be connected by an outlet to the clamping press. The device further comprises a valve unit for controlling the application of the pressure medium to the clamping press, wherein the valve unit can be directly controlled by the stroke motion of the piston. The method according to the invention provides for clamping the tension member as a function of the clamping force of the reference tension member by the cylinder piston unit, the piston thereof holding the reference tension member in a predetermined stress state. When a uniform stress state is achieved in all tension members in the course of clamping the tension member by a clamping press, the inflow of the pressure medium to the clamping press is directly interrupted by the stroke motion of the piston. | 07-14-2011 |
Hagen Kempas, Uberlingen DE
| Patent application number | Description | Published |
|---|---|---|
| 20090027750 | Optical Swiveling Device - An optical swiveling device is specified for imaging and/or projection of an object scene, having a supporting structure, having a detection/transmission unit arranged in the supporting structure, having a pitch frame and having a roll frame, with the pitch frame being mounted in the roll frame such that it can rotate about a pitch axis and with the roll frame being mounted in the supporting structure such that it can rotate about a roll axis. In this case the pitch axis and the roll axis intersect at an intersection angle of less than 90°. First deflection optics are arranged in the pitch frame such that a beam propagating along the pitch axis is deflected in an object-side direction which intersects the pitch axis at the intersection angle, and vice versa, and second deflection optics are arranged in the roll frame such that a beam propagating along the pitch axis is deflected in the direction along the roll axis, and vice versa. | 01-29-2009 |
Hagen Klauk, Stuttgart DE
| Patent application number | Description | Published |
|---|---|---|
| 20080275273 | Method for Synthesizing Long-Chain Phosphonic Acid Derivatives and Thiol Derivatives - A process for synthesizing long-chain phosphonic acid derivatives and thiol derivative is disclosed. One embodiment provides organic compounds which can form a self-assembled monolayer and are obtained by reaction of an olefin with a thiocarboxylic acid and subsequent hydrogenation to give the thiol, or with a phosphite and subsequent hydrolysis to give the phosphonic acid. | 11-06-2008 |
| 20080290337 | Ultrathin Dielectrics and the Application Thereof in Organic Field Effect Transistors - An organic field effect transistor, having a substrate, a source electrode, a drain electrode and a gate electrode and an organic semiconductor material is disclosed. Arranged between the gate electrode and the organic semiconductor material is a dielectric layer (gate dielectric) obtained from a self-assembled monolayer of an organic compound having an anchor group, a linker group, a head group, and an aliphatic orientating group, the anchor group, the linker group, the head group, and the aliphatic orientating group being combined with one another in the order stated. | 11-27-2008 |
| 20080315192 | Integrated Circuit Comprising an Organic Semiconductor, and Method for the Production of an Integrated Circuit - An embodiment of the invention provides an integrated circuit having an organic field effect transistor (OFET) with a dielectric layer. The dielectric layer is prepared from a polymer formulation comprising: about 100 parts of at least one crosslinkable base polymer, from about 10 to about 20 parts of at least one di- or tribenzyl alcohol compound as an electrophilic crosslinking component, from about 0.2 to about 10 parts of at least one photo acid generator, and at least one solvent. Another embodiment provides a semiconductor fabrication method. The method comprises applying the polymer formulation to a surface of a substrate, drying the polymer formulation, crosslinking the polymer formulation after drying, and baking the polymer formulation after crosslinking. | 12-25-2008 |
| 20090066345 | SENSOR HAVING ORGANIC FIELD EFFECT TRANSISTORS - A force sensor based on an organic field effect transistor applied on a substrate is disclosed. In one embodiment, a mechanical force acting on the transistor causes a change in its source-drain voltage or its source-drain current which corresponds to said force and which can in each case be detected as measurement quantity for the acting force, a diaphragm-based pressure sensor that uses a force sensor of this type, a one- or two-dimensional position sensor that uses a multiplicity of force sensors of this type, and a fingerprint sensor that uses a multiplicity of such force sensors. | 03-12-2009 |
Hagen Luckner, Pentling DE
| Patent application number | Description | Published |
|---|---|---|
| 20110215369 | LUMINESCENCE DIODE CHIP - A luminescence diode chip includes a semiconductor layer sequence having an active layer suitable for generating electromagnetic radiation, and a first electrical connection layer, which touches and makes electrically conductive contact with the semiconductor layer sequence. The first electrical connection layer touches and makes contact with the semiconductor layer sequence in particular with a plurality of contact areas. In the case of the luminescence diode chip, an inhomogeneous current density distribution or current distribution is set in a targeted manner in the semiconductor layer sequence by means of an inhomogeneous distribution of an area density of the contact areas along a main plane of extent of the semiconductor layer sequence. | 09-08-2011 |
Hagen Mittelstrass, Bondorf DE
| Patent application number | Description | Published |
|---|---|---|
| 20090126920 | Heat exchanger for a motor vehicle - Disclosed herein is a heat exchanger with tubes ( | 05-21-2009 |
Hagen Schempf, Pittsburgh, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20090266628 | Stair climbing tread hardware for a robot - An easily and quickly reconfigurable robot chassis with at least a pair of forward shafts and a pair of rearward shafts. A wheel is attachable to and removable from each drive shaft. A sprocket is also attachable to and removable from each shaft. A first pair of tracks each extend around opposing forward sprockets and rearward sprockets. A pair of forward track extenders are each removeably attachable to the chassis and each include a forward idler sprocket. A second pair of longer tracks each extend around opposing rearward sprockets, the forward sprockets, and forward idler sprockets. A pair of rearward track extenders are each removeably attachable to the chassis and each include a rearward idler sprocket. A third pair of still longer tracks each extend around opposing rearward idler sprockets, rearward sprockets, forward sprockets, and forward idler sprockets. | 10-29-2009 |
Hagen Schmidt, Hannover DE
| Patent application number | Description | Published |
|---|---|---|
| 20110107806 | DEVICE AND NON-CUTTING SHAPING METHOD FOR INTRODUCING AN OUTSIDE PROFILE INTO A WORKPIECE - A portable handheld device for introducing an external profile into a longitudinal workpiece by noncutting shaping includes a locking element and a profiling tool having a pitchless profile disposed opposite the locking element and disposable at an adjustable angle as a function of a desired lead angle of the external profile within a force transmission plane, wherein the workpiece is disposable and removable between the profiling tool and the locking element, and wherein the profile tool and the locking element are configured to execute a feed movement relative to one another and to be adjustable to a neutral position. | 05-12-2011 |
Hagen Stawitzki, Karlsruhe DE
| Patent application number | Description | Published |
|---|---|---|
| 20090012229 | PARTIALLY AROMATIC COPOLYAMIDES WITH A HIGH CRYSTALLINITY - Semiaromatic semicrystalline thermoplastic polyamide molding compositions, comprising | 01-08-2009 |
| 20100090174 | THERMOPLASTIC MOULDING COMPOSITIONS HAVING IMPROVED DUCTILITY - Thermoplastic molding compositions comprising | 04-15-2010 |
| 20100190934 | METHOD FOR PRODUCING POLYAMIDES - The process for preparing a polyamide based on dicarboxylic acids and diamines has the following stages: | 07-29-2010 |
| 20100190952 | METHOD FOR THE PRODUCTION OF POLYAMIDES IN EXTRUDERS - In a process for preparing a polyamide based on dicarboxylic acids and diamines in an extruder, a solid mixture comprising a monomer mixture composed of 50 mol % of dicarboxylic acid mixture composed of from 60 to 88 % by weight of terephthalic acid and from 12 to 40% by weight of isophthalic acid, in which up to 20% by weight of the dicarboxylic acid mixture may also be replaced by other dicarboxylic acids, and 50 mol % of hexamethylenediamine which may be up to 20% by weight replaced by other C | 07-29-2010 |
Hagen Stuebing, Buedingen DE
| Patent application number | Description | Published |
|---|---|---|
| 20120077430 | TRANSMITTING DEVICE, RECEIVING DEVICE, COMMUNICATION SYSTEM, AND METHOD FOR OPERATING A TRANSMITTING DEVICE AND A RECEIVING DEVICE - A transmitting device is provided for a communication system, which has at least one transmitting antenna, the at least one transmitting antenna being implemented to generate an emission field by emitting electromagnetic waves in an emission region. In addition, the transmitting device has a first ascertainment device, which is implemented to ascertain whether at least one receiving device for receiving the emitted electromagnetic waves, which forms a non-trustworthy receiver, is situated inside the emission region. In addition, the transmitting device has a first adaptation device, which is implemented to adapt an emission field of the at least one transmitting antenna, if at least one receiving device, which forms a non-trustworthy receiver, is ascertained inside the emission region, in such a manner that a field strength of the electromagnetic waves is reduced at the location of the at least one receiving device. | 03-29-2012 |
Hagen Terpitz, Hemhofen/zechem DE
| Patent application number | Description | Published |
|---|---|---|
| 20090072986 | Motion Monitoring - There is described a method for motion monitoring of a machine, comprising a sensor, wherein a sensor signal is transmitted from the sensor to a controller and/or to a drive device, a failsafe controller or drive device being employed as controller or drive device. The controller or drive device comprises three independent monitoring devices in which the sensor signal is formed from a first and a second redundant actual position value. | 03-19-2009 |
Hagen Voelzer, Zurich CH
| Patent application number | Description | Published |
|---|---|---|
| 20090150860 | METHOD AND SYSTEM FOR COMBINING QUALITY ASSURANCE AND MODEL TRANSFORMATIONS IN A BUSINESS-DRIVEN DEVELOPMENT ENVIRONMENT - A system for combining quality assurance and model transformations in a business-driven development environment includes a host system executing a business modeling application, a transformation framework including a transformation programming interface (TPI) and a quality assurance framework executing on top of the business modeling application, and a plurality of transformation plug-in tools in communication with the TPI. The TPI includes options for model access and traversal, model element creation/removal, model element property editing and analysis. The options are applied to the transformations, via the selected transformation plug-in tools, to a business model resulting in a modified business model that conforms to an information technology (IT)-based executable code. The quality assurance framework performs single-entry-single-exit (SESE) fragment decomposition of the modified business model, control-flow analysis, and notification to the user of any detected error conditions, the notification presented to the user with the modified business model via the TPI. | 06-11-2009 |
| 20090187881 | DIFFERENCE LOG PRODUCTION FOR MODEL MERGING - Methods and apparatus are provided for production of a difference log in a data processing system The difference log defines differences between process models defined in system memory. For each of the process models, model structure data provided in memory defines a hierarchy of SESE regions representing the structure of that model. Also provided in memory are model comparison data defining correspondences between elements of the models, and region comparison data defining correspondences between regions of the SESE region hierarchies for the models. The model comparison and region comparison data are analyzed to identify differences between the SESE region hierarchies, and a difference log defining said differences is produced. In preferred systems, the model structure data and the region comparison data is computed for the models, and the difference log has a hierarchical structure corresponding to the structure of the process models. | 07-23-2009 |
| 20100079458 | SYSTEM AND METHOD FOR HIERARCHICALLY DECOMPOSING PROCESS MODEL - A system and associated method for hierarchically decomposing a workflow graph G into a process structure tree PST. The workflow graph G is a two-terminal graph parsed into a tree T having triconnected components. Boundary pairs of all triconnected components in T are computed and fragments are discovered with boundary pairs. T is restructured into PST pursuant to categories of triconnected components in T. PST is deterministic and modular. PST represents a block-based process model that has fine blocks of execution units. PST is computed in time linear to the number of edges in G. | 04-01-2010 |
Hagen Von Briesen, Hünstetten DE
| Patent application number | Description | Published |
|---|---|---|
| 20090029470 | PROCESS AND CULTURING UNIT FOR CULTURING BIOLOGICAL CELLS - A targeted cultivation phase adjustment is provided in a process for the cultivation of cells in which biological cells are cultivated on at least one boundary surface between different, non-solid cultivation phases so that pre-determined cultivation conditions are given. A cultivation apparatus ( | 01-29-2009 |
| 20110308333 | SAMPLE CHAMBER ADAPTER, IN PARTICULAR FOR THE CRYOCONSERVATION OF BIOLOGICAL SAMPLES - An adapter device includes a receptacle including at least one receiving element that detachably secures a sample chamber for cryoconservation of a biological sample, and a coupling device that connects the receptacle to a base section which can be secured in a cooling device, wherein the receiving element is 1) immobile in a holding state at a cryoconservation temperature and secures the sample chamber and 2) at least one of deformable and movable in a release state at a temperature above the cryoconservation temperature so that the sample chamber is detachable from the adapter device or can be inserted into the adapter device. | 12-22-2011 |
Hagen Von Briesen, Hünstetten DE
| Patent application number | Description | Published |
|---|---|---|
| 20090029470 | PROCESS AND CULTURING UNIT FOR CULTURING BIOLOGICAL CELLS - A targeted cultivation phase adjustment is provided in a process for the cultivation of cells in which biological cells are cultivated on at least one boundary surface between different, non-solid cultivation phases so that pre-determined cultivation conditions are given. A cultivation apparatus ( | 01-29-2009 |
| 20110142948 | Nanoparticle Carrier Systems based on Human Serum Albumin for Photodynamic Therapy - Compositions, which are stable in storage, and a method of production of pharmaceutical based nanoparticulate formulations for photodynamic therapy comprising a hydrophobic photosensitizer, human serum albumin (HSA) and stabilizing agent are provided. These nanoparticulate formulations provide therapeutically effective amounts of photosensitizer (PS) for parenteral administration. In particular, tetrapyrrole derivatives can be used as photosensitizers whose efficacy and safety are enhanced by such nanoparticulate formulations. A method of preparing the HSA-based nanoparticles under sterile conditions is also provided. In one of the preferred embodiments of the present invention temoporfin, a hydrophobic PS, is formulated as a nanoparticle for parenteral administration. The formulations are useful for treating hyperplasic and neoplasic conditions, inflammatory problems, and more specifically to target tumor cells. | 06-16-2011 |
| 20110275686 | NANOPARTICLE CARRIER SYSTEMS BASED ON POLY(DL-LACTIC-CO-GLYCOLIC ACID) (PLGA) FOR PHOTODYNAMIC THERAPY (PDT) - Compositions, which are stable in storage, and a method of production of pharmaceutical based nanoparticulate formulations for clinical use in photodynamic therapy comprising a hydrophobic photosensitizer, poly(lactic-co-glycolic) acid and stabilizing agents are provided. These nanoparticulate pharmaceutical formulations provide therapeutically effective amounts of photosensitizer for parenteral administration. In particular, tetrapyrrole derivatives can be used as photosensitizers, whose efficacy and safety are enhanced by such nanoparticulate formulations. It also teaches the method of preparing PLGA-based nanoparticles under sterile conditions. In one of the preferred embodiments of the present invention PLGA-based nanoparticles have a mean particle size less than 500 nm and the photosensitizer is temoporfin, 5,10,15,20-tetrakis(3-hydroxyphenyl)-chlorin (mTHPC). In another embodiment, the photosensitizer 2,3-dihydroxy-5,10,15,20-tetrakis(3-hydroxyphenyl)-chlorin (mTHPD-OH) is formulated as a nanoparticle for parenteral administration. Yet, in another embodiment preferred photosensitizer is 5,10,15,20-tetrakis(3-hydroxyphenyl)-porphyrin (mTHPP). The formulations can be used for treating hyperplasic and neoplasic conditions, inflammatory problems, and more specifically to target tumor cells. | 11-10-2011 |
Hagen Zeißmann, Herrenberg DE
| Patent application number | Description | Published |
|---|---|---|
| 20090320926 | TANK VENTILATION DEVICE AND ASSOCIATED OPERATING METHOD - The present invention relates to a tank ventilation device ( | 12-31-2009 |
Hagen Zimer, Jena DE
| Patent application number | Description | Published |
|---|---|---|
| 20090028495 | ELECTRO-OPTICAL HYBRID CONNECTION ASSEMBLY - An electro-optical hybrid connection assembly provides an optical connection of at least a first optical fiber and a second optical fiber that define a fiber axis and an electrical connection of at least a first electrical conductor and a second electrical conductor. The assembly includes a first connector and a second connector. The first connector includes a first ferrule that encloses the first optical fiber, a centering sleeve surrounding the first ferrule and projecting beyond at least one end of the first ferrule, and at least one electrical plug-in contact connected to the first electrical conductor. The second connector includes a second ferrule enclosing the second optical fiber, and at least one electrical plug-in contact connected to the second electrical conductor. Each of the two optical fibers has a plane fiber end aligned at right angles to the fiber axis and provided with an anti-reflection coating. | 01-29-2009 |
| 20090046752 | GAS-COOLED LASER DEVICE - A gas-cooled laser device includes heat dissipative components, and housing walls made of a heat conducting material, in which one or more of the housing walls are provided with ventilation channels. At least one heat dissipative component is mounted on a plate of a heat conducting material, and the heat conducting plate is connected in a thermally conducting manner with the at least one housing wall that is provided with ventilation channels. The heat dissipative components can include heat dissipative optical components and heat dissipative non-optical components that are respectively arranged on different sides of the plate or are respectively arranged in different compartments on one side of the plate. | 02-19-2009 |
| 20100303105 | GENERATING PULSE TRAINS IN Q-SWITCHED LASERS - The invention relates to methods and systems for generating a pulse train having several individual pulses, wherein the individual pulses have a desired pulse characteristic, by means of a Q-switched solid state laser system, which includes, e.g., a modulator for influencing the pulse characteristic of the individual pulses. The methods include (a) generating individual pulses of a pulse train, each pulse having a pulse characteristic, by applying a temporal initial modulation signal; (b) detecting the pulse characteristic of the individual pulses of the generated pulse train; (c) generating a modified modulation signal in correlation to the detected and the desired pulse characteristic of the individual pulses of the pulse train, and applying the modified modulation signal to the modulator to generate a pulse train with a modified pulse characteristic; (d) repeating step (c) until the modified pulse characteristic fulfills a predetermined termination criterion and then using the modified modulation signal as an optimum modulation signal; and (e) generating a pulse train with the desired pulse characteristic of the individual pulses thereof by applying the optimum modulation signal. | 12-02-2010 |