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Hafler
David Hafler, Newton, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20110245107 | SELECTIVE DIFFERENTIATION, IDENTIFICATION, AMD MODULATION OF HUMAN TH17 CELLS - The embodiments provide for the modulation of both the differentiation and activity of human TH17 cells. More specifically, human TH17 cell differentiation can modulated by TGF-? and IL-21, and their agonists and antagonists. Function of TH17 cells can be modulated by, for example, BLT1 or podoplanin, and their agonists and antagonists. Additionally, the embodiments provide for the identification of TH17 cells. More specifically, human TH17 cells specifically upregulate BLT1 and podoplanin. | 10-06-2011 |
David A. Hafler, Boston, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100061992 | THERAPEUTIC USES OF TIM-3 MODULATORS - The invention provides novel methods of treating neurological disorders, including neurodegenerative disorders such as MS. The invention also provides novel methods of treating cancers, including glial tumors such as glioblastoma multiforme. The invention further provides vaccines and related uses. | 03-11-2010 |
David A. Hafler, Newton, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090054251 | Diagnosis of Autoimmune Disease - Methods and compositions for diagnosing and treating autoimmune disease, e.g., acute disseminated encephalomyelitis (ADEM), are described. | 02-26-2009 |